Applying dynamical systems theory to single-cell data can provide a detailed picture of the cellular states observed during cell fate decisions. This study presents a dynamic landscape analysis (DLA) ...

A new AI for Biological Discovery Seminar Series, presented by the Francis Crick Institute.

In cell biology, computational models of biological systems range from minimal representations with a handful of parameters to whole-cell simulations tracking thousands of molecular species across a c...

snRNA-seq reveals shoot stem cell heterogeneity and traces their differentiation into primary stem cell types.

How rigid a tissue is coordinates a crucial period of cell patterning, ensuring that embryos develop the right shape and organise their cell layers correctly at the same time.

a truly interdisciplinary workshop

Applications are invited for a Research Assistant position in the group of Dr Sarah Robinson at the Sainsbury Laboratory Cambridge University. The successful applicant will be part of a group that inv...

Postdoc Pönisch Lab

Nature Reviews Genetics - In this Perspective, Maizels and Briscoe discuss the limitations of current models of gene regulatory networks and outline solutions to harness data abundance without...

Assurez-vous que votre profil candidat soit correctement renseigné avant de postuler

Benzinger et al. develop a chemo-optogenetic system for precise spatiotemporal control of morphogen production in vitro. Using light-controlled Sonic hedgehog expression, they recapitulate neural tube...

Jaxley is a versatile platform for biophysical modeling in neuroscience. It allows efficiently simulating large-scale biophysical models on CPUs, GPUs and TPUs. Model parameters can be optimized with ...

RESYDE: Re-engineering symmetry breaking in development and evolution. A consortia of plant scientists from Europe and Australia has been awarded a prestigious research grant from the ERC, which will ...

The authors present a computational framework that leverages mechanical force inference and spatial transcriptomics to enable analyses of the interplay between the transcriptomic and mechanical state.