iiinova — where your digital self keeps evolving

Reposted by Will Hooper

Jesse Boehm @boehmjesse.bsky.social · 05/08/2026

Hot off the press in Nature! After 10 years, 2,780 patients and 300+ scientists, today we announce the Human Cancer Models Initiative (HCMI) release of 665 organoids and other next generation models! All models and data available to accelerate cancer drug discovery! @nature.com rdcu.be/fx3I3

rdcu.be

A compendium of next-generation patient-derived models for diverse cancers

Nature - The international collaboration of the Human Cancer Models Initiative presents a comprehensive resource of next-generation cancer models from 2,780 donors with 25 cancer types and...

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Reposted by Will Hooper

New York Genome Center @nygenome.org · 05/08/2026

We're proud to share this important work, with contributions from NYGC scientists, Nicolas Robine, William Hooper, Tim Chu, and Jennifer Shelton. This transformative resource will help advance cancer research and accelerate scientific discovery @nicorobine.bsky.social x.com/CSHL/status/...

x.com

Cold Spring Harbor Laboratory (@CSHL) on X

The next generation of cancer research models has arrived. An international consortium led by CSHL and @NorthwellHealth has developed more than 150 organoid models representing actual patient tumors s...

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Reposted by Will Hooper

Nicolas Robine 🇪🇺🇫🇷🇺🇸 @nicorobine.bsky.social · 05/05/2026

⚠️Preprint alert⚠️: we set up Polyethnic-1000 at @nygenome.org to study the molecular basis of cancer disparities. One striking example is endometrial cancer, with much higher mortality in patients of African ancestry.

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Reposted by Will Hooper

Nicolas Robine 🇪🇺🇫🇷🇺🇸 @nicorobine.bsky.social · 14/03/2026

Despite the obvious superiority of fresh-frozen material for genomics, many samples are still stored in FFPE and remain challenging to characterize with Whole-genome sequencing. But here comes our solution:

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Reposted by Will Hooper

Hadley Wickham @hadley.nz · 11/06/2025

Happy 18th birthday ggplot2! #rstats

Balloon wall art inspired by the ggplot2 hex sticker. The display features a hexagonal frame made of black balloons, filled with white balloons inside and surrounded by a background of light and dark blue balloons. A line graph with black balloon segments and round coloured nodes runs across the centre, and the word “ggplot2” is spelled out in black balloon letters below the chart.

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Reposted by Will Hooper

Alex @alexpellancheng.bsky.social · 11/04/2025

What happens when sequencing costs go ⏬ ? Imagination and new opportunities go ⏫ @landau.bsky.social Let's look at what you can do when you perform deep WGS on cfDNA for cancer detection. Our recent work with the @UltimaGenomics platform 🧵👇 Lets goooo!! rdcu.be/ehkUb

rdcu.be

Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling

Nature Methods - This work integrates duplex sequencing with cost-effective Ultima sequencing to enhance the accuracy of whole-genome circulating cell-free DNA profiling.

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Reposted by Will Hooper

Nicolas Robine 🇪🇺🇫🇷🇺🇸 @nicorobine.bsky.social · 31/03/2025

New publication from my @nygenome.org group, in close collaboration with @wcmenglanderipm.bsky.social colleagues Jones Nauseef, Juan-Miguel Mosquera! A complex phylogeny of lineage plasticity in metastatic castration resistant prostate cancer www.nature.com/articles/s41...

nature.com

A complex phylogeny of lineage plasticity in metastatic castration resistant prostate cancer - npj Precision Oncology

npj Precision Oncology - A complex phylogeny of lineage plasticity in metastatic castration resistant prostate cancer

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Reposted by Will Hooper

bioRxiv Genomics @biorxiv-genomic.bsky.social · 24/02/2025

Sequencing by Expansion (SBX) -- a novel, high-throughput single-molecule sequencing technology www.biorxiv.org/content/10.1101/202…

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Reposted by Will Hooper

bioRxivpreprint @biorxivpreprint.bsky.social · 23/02/2025

Lancet2: Improved and accelerated somatic variant calling with joint multi-sample local assembly graph www.biorxiv.org/content/10.1101/202…

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Reposted by Will Hooper

Prasad Jallepalli, MD, PhD @prasad.bsky.social · 14/02/2025

www.nytimes.com/2025/02/14/o... An eloquent defense of American science by Harold Varmus, a Nobel Prize winning scientist during his days at UCSF, former director of the NIH and NCI, and former President of Memorial Sloan Kettering Cancer Center (full disclosure — it’s where I work)

nytimes.com

Opinion | American Science is Under Attack (Gift Article)

The Trump administration hobbles research and endangers the public health.

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Reposted by Will Hooper

Nicolas Robine 🇪🇺🇫🇷🇺🇸 @nicorobine.bsky.social · 10/02/2025

Petition to Reverse the NIH Indirect Cost Cap. Sign and Circulate. Mobilize. Organize. chng.it/LS57Nk7r6k

chng.it

This campaign needs you now

Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)

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