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Alex

@alexpellancheng.bsky.social
91 followers 278 following 27 posts

ohhhmics | Associate Professor at ETSmtl & CRCHUM | 🐶🧬☕️ 🐥 pellanchenglab.github.io/#join

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Alex @alexpellancheng.bsky.social · 14/08/2025
Highly accurate sequencing OR high throughput? We refuse to choose. Introducing ppmSeq, a method built to deliver both. Our latest from the @landau.bsky.social lab with Ultima Genomics 👀👀👀 See ⬇️ for a primer on the next frontier of genomics www.biorxiv.org/content/10.1...
biorxiv.org
Paired plus-minus sequencing is an ultra-high throughput and accurate method for dual strand sequencing of DNA molecules
Distinguishing real biological variation in the form of single-nucleotide variants (SNVs) from errors is a major challenge for genome sequencing technologies. This is particularly true in settings whe...
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Alex @alexpellancheng.bsky.social · 11/04/2025
What happens when sequencing costs go ⏬ ? Imagination and new opportunities go ⏫ @landau.bsky.social Let's look at what you can do when you perform deep WGS on cfDNA for cancer detection. Our recent work with the @UltimaGenomics platform 🧵👇 Lets goooo!! rdcu.be/ehkUb
rdcu.be
Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling
Nature Methods - This work integrates duplex sequencing with cost-effective Ultima sequencing to enhance the accuracy of whole-genome circulating cell-free DNA profiling.
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