From today, all new submissions to Nature that are published will be accompanied by referees’ reports and author responses — to illuminate the process of producing rigorous science.

Abstract. Plants are essential for life as we know it on Earth. They oxygenate the atmosphere, regulate the climate, and comprise much of the primary produ

Single-cell RNA sequencing and spatial transcriptomic approaches reveal major expression changes in outer root cell types when grown in soil versus gel conditions, and also uncover how root tissu...

A MYB transcription factor acts as a regulator to prevent degradation of a key component of the iron deficiency response involved in maintaining iron homeo

Prof David Liu is among the winners of 2025’s ‘Oscars of science’, with honours also going to researchers for landmark work on multiple sclerosis, particle physics and ‘skinny jabs’

Osborne et al. show that the angiosperm-specific PRC2 subunit VRN2 is enriched in hypoxic regions of the Arabidopsis shoot, where it is required for stable deposition of H3K27me3 in key PIF4 target ge...

Osborne et al. show that the angiosperm-specific PRC2 subunit VRN2 is enriched in hypoxic regions of the Arabidopsis shoot, where it is required for stable deposition of H3K27me3 in key PIF4 target ge...

Proteins operate through ligand and solvent interactions governed by thermodynamics, yet the enthalpy-entropy trade-offs that guide their functional evolution remain poorly understood. The LacI/GalR f...

Studies on climate change and South Africa are also on the latest list of grants to be terminated, according to updated documents obtained by Nature.

Following an international search, Professor Cristóbal Uauy has been appointed as the next Director of the John Innes Centre. Professor Uauy is internationally recognised for his significant…

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

The Melt (Membrane localization using temperature) protein translocates to the plasma membrane upon temperature shift. Melt variants with a range of switching temperatures enable straightforward therm...

Biomolecular condensates are membraneless organelles that concentrate proteins and nucleic acids. One of the primary components of condensates is mult…

Stress granules, cellular structures essential for stress response, require poly(ADP-ribose) as a multivalent scaffold. Here, the authors show that disrupting poly(ADP-ribose) binding to PARP13 alters...

Plants are able to sense and remember heat stress. An initial priming heat stress enables plants to acclimate so that they are able to survive a subsequent higher temperature. The heatshock transcription factors (HSFs) play a crucial role in this process, but the mechanisms by which plants sense heat stress are not well understood. By comprehensively analyzing the binding targets of all the HSFs, we find that HSFs act in a network, with upstream sensory acting in a transcriptional cascade to activate downstream HSFs and protective proteins.

Plants are able to sense and remember heat stress. An initial priming heat stress enables plants to acclimate so that they are able to survive a subsequent higher temperature. The heatshock transcription factors (HSFs) play a crucial role in this process, but the mechanisms by which plants sense heat stress are not well understood. By comprehensively analyzing the binding targets of all the HSFs, we find that HSFs act in a network, with upstream sensory acting in a transcriptional cascade to activate downstream HSFs and protective proteins.

Population mutation rates are highly flexible and evolvable under extreme stress conditions, matching changes in selective pressure to avoid extinction of the entire population.