Peroxiredoxin 1 (PRDX1) is a highly conserved, thiol-dependent peroxidase that rapidly scavenges reactive oxygen species to modulate redox signaling. PRDX1-null mice exhibited genomic instability, sho...

Peroxiredoxin 1 (PRDX1) is a highly conserved, thiol-dependent peroxidase that rapidly scavenges reactive oxygen species to modulate redox signaling. PRDX1-null mice exhibited genomic instability, sho...

New methods allow scientists to use a powerful technique known as cryo-EM to examine proteins that have been difficult to study so far.

Targeting two proteins that cancer cells rely on to sustain their metabolism and DNA repair capabilities can double the survival rate of mice with lung cancer tumors. Cross referencing with data from ...

In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.

Metabolic pathways fuel tumor progression and resistance to stress conditions including chemotherapeutic drugs, such as DNA damage response (DDR) inhi…

Drinking alcohol raises the risk of developing seven types of cancer, according to a new advisory from U.S. Surgeon General Vivek Murthy.

📢🧬I have a postdoc position open for people with experience using QM/MM on biosystems! Do not hesitate to apply if you're interested in investigating the…

Three senior figures at the US National Institutes of Health explain why the agency remains committed to supporting basic science and research.

In vivo metastasis modeling and CRISPR screening identify mediators of ovarian cancer metastasis to distant organs, highlighting the dual functions of unsaturated lipids in promoting extravasation and colonization.

The experience with PARP inhibitors provides evidence of the clinical utility of synthetic lethality, whereby the simultaneous presence of two specific alterations is required for antitumour activity....

A scientist simulated the contents of the ice giant worlds, and found that a fluid layer may explain each planet’s strange magnetic field.