Humans can combine symbols to generate new meanings. Here, we studied the regional neural mechanisms that might make this possible. We asked participa…

ALT: a black cat is sitting in the snow with the words still waiting below it .

The neural mechanisms of multiple-item working memory are not well understood. In the current study, we address two competing hypotheses about the neural basis of sequential working memory: neural sub...

A core function of visual working memory (WM) is to sustain mental representations of recent visual inputs, thereby bridging moments of experience. This is thought to occur in part by recruiting early...

The Medial Temporal Lobe (MTL) is key to human cognition, supporting memory, emotional processing, navigation, and semantic coding. Rare direct human MTL recordings revealed concept cells, which were ...

Nature Communications - Eye movements during scene viewing are tied to grid-like codes in the entorhinal cortex. Grid signals are specific to later remembered scenes, covary with activity in...

A core function of visual working memory (WM) is to sustain mental representations of recent visual inputs, thereby bridging moments of experience. This is thought to occur in part by recruiting early ‘sensory’ cortical regions, via flexible fronto-parietal mechanisms. The nature of visual cortex activity during WM has been elusive, but new evidence suggests that early WM representations can transform from a sensory-like code into a format that is shaped by task context and optimized for behavior. Here, we review evidence for transformations in visual cortical WM coding, the various forms they take, and their functional importance. Visual cortex may be an active workspace during WM, where flexible and ‘good enough’ WM representations serve to interface with perception and action.

The role of the hippocampus in resolving memory interference has been greatly elucidated by considering the relationship between the similarity of visual stimuli (input) and corresponding similarity o...

The neural grid code has been proposed to provide a mechanism for generalization and transfer of relational knowledge between situations enabling rapid adaptation of behavior in novel circumstances. H...

Neurons that respond emergently to illusory contours drive pattern completion in V1. Pattern completion in lower cortical areas may therefore mediate perceptual inference by selectively reinforcing ac...

Increasing working memory (WM) load incurs behavioral costs, and whether the neural constraints on behavioral costs are localized (i.e., emanating from the intraparietal sulcus) or distributed across ...

Author summary Why do some people forget faster than others? This study investigates individual differences in long-term memory forgetting by linking them to patterns of brain connectivity. Although m...

When people recall a movie, their eye movements and brain activity resemble those observed during the viewing. These behavioral and neural reactivations are linked through a common process, likely ref...

Humans can implicitly learn about multistep sequential relationships between events in the environment from their statistical co-occurrence. Theore...

Removing irrelevant information from working memory (WM) can free cognitive resources and reduce interference with current task goals. Beyond these...

Author summary In everyday life, we focus on what matters—like finding our car keys on a messy desk—by sending signals from higher control brain areas to earlier sensory brain areas. These “top-down” ...

Attention flexibly modulates sensory contents in working memory, but the dynamics of motor content modulation in working memory remain unclear. This study shows that brain representations of both sens...

Navigating the environment involves engaging with multiple objects, each activating specific neuronal populations. When objects appear together, these populations compete. Classical attention theories...

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Magnetoencephalographic recordings revealed a direct neural signature of serial dependence, that is, an attractive bias of current toward previous representations, which emerged at late, post-encoding...

The hippocampus is thought to encode the content of stimuli, but how it does so is unknown. The authors show that when hippocampal spiking variability tracks the abstract building blocks of individual...