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Marcel S. Kehl

@mskehl.bsky.social
350 followers 630 following 20 posts

Oxford Postdoc in the Staresina Lab | Sleep | Memory | Human Olfaction & Single Neurons

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Reposted by Marcel S. Kehl
Scott Cairney @sacairney.bsky.social · 28/09/2026
Fully funded PhD studentship investigating sleep’s role in forgetting unwanted memories at my lab at @yorkpsychology.bsky.social, starting in September 2027. Funding includes UK home fees and a 3-year tax-free stipend (~£22K per year). Please share widely www.findaphd.com/phds/project...
findaphd.com
Forgetting unwanted memories during sleep at University of York on FindAPhD.com
PhD Project - Forgetting unwanted memories during sleep at University of York, listed on FindAPhD.com
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Sander van Bree @sandervanbree.bsky.social · 12/08/2026
Excited to share our preprint! w/ @martinhebart.bsky.social To understand how primates visually process objects in the world, we rely on both research in human and macaque IT. But what representations of object space are actually shared between them? biorxiv.org/content/10.6... Quick thread 🧵
biorxiv.org
Shared and Distinct High-Dimensional Object Spaces in Human and Macaque Inferotemporal Cortex
Human and macaque studies of inferotemporal cortex (IT) have shaped our understanding of object vision, yet the extent of their representational alignment and the precise nature of this correspondence...
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Esteban @estebanbt.bsky.social · 05/08/2026
Summer Preprint Alert 🔥🚨 Breathing isn't just for oxygen; it’s a rhythmic pacemaker for the sleeping brain. Our new preprint shows that the respiratory cycle actually gates memory reactivation during NREM sleep! 🧠😴💨 👇🧵(1/8)
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Alana Darcher @alanadarcher.bsky.social · 30/07/2026
🎉 *extremely* excited to share our human single neuron + movie dataset is out in #ScientificData! 📄 Human neuron activity during an 83-minute movie from 2,286 neurons and 29 patients 🔗https://www.nature.com/articles/s41597-026-07955-0 1st public dataset from @humansingleneuron.bsky.social!🧵
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Neil Burgess @neilburgess10.bsky.social · 01/07/2026
Ever wondered how the hippocampal cognitive map is read-out? @changmin-yu.bsky.social @zilong-ji.bsky.social with Jake & John, show that, during navigation, theta sweeps indicate remembered goal-directions (cf. current/next movements or perceptual targets) 1/2 www.nature.com/articles/s41...
Decoded locations from place cell firing sweep towards a remembered goal location during each theta cycle irrespective of the current movement or head direction
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Liz Siefert @lizsiefert.bsky.social · 29/06/2026
New preprint! We show low arousal states promote hippocampal ripple genesis in sleep and wake. This bridges rodent work, where ripples predominate during sleep, with human studies reporting ripples during active behavior, identifying low arousal as a common mechanism www.biorxiv.org/content/10.6...
biorxiv.org
Arousal state modulates human hippocampal ripples
Hippocampal ripples are transient, high-frequency oscillations linked to memory replay and consolidation. Ripples are well-characterized in rodents to occur during periods of behavioral inactivity (i....
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Sophia Wilhelm @sophiawilhelm.bsky.social · 28/06/2026
🔔 Our new preprint is out! Here we asked whether sleep spindles - a hallmark NREM rhythm linked to plasticity and memory - changes how well latent working memory representations can be accessed after a nap.
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 28/06/2026
Sleep spindles enhance latent working memory representations www.biorxiv.org/content/10.64898/20…
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acausse.bsky.social @acausse.bsky.social · 08/06/2026
🧵 How does the human brain turn experiences into memories? During my four years of PhD at Oxford, I investigated this question through a collaboration between Oxford, Toulouse, and Paris, recording directly from the human brain during a relational memory task.
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Pin-Chun Chen @pinchunc.bsky.social · 18/05/2026
🔔 Preprint: “Hippocampal ripples evoke a stereotyped cortical response followed by spindle-mediated network synchronization.” Combining iEEG+scalp EEG during sleep, we show that hippocampal ripples leave a decodable cortical fingerprint and are followed by brain-wide spindle synchronization!
doi.org
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Martin Hebart @martinhebart.bsky.social · 17/05/2026
I'm proud to say we are releasing LAION-fMRI, a densely sampled 7T fMRI dataset of natural images, with very broad stimulus sampling for testing countless hypotheses and for deeply exploring brain representations. The dataset is now available at laion-fmri.hebartlab.com What does LAION-fMRI offer? 🧵
laion-fmri.hebartlab.com
LAION-fMRI - a 7T fMRI dataset of human vision
LAION-fMRI (LfMRI / LAION MRI dataset): 5 subjects, 25,052 launch-release natural images, 165 acquired 7T fMRI sessions with single-trial GLMsingle betas, retinotopy, localizers, and diffusion.
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Tobias Ackels @tobiasackels.bsky.social · 12/05/2026
🚨 Preprint alert! 🚨 How does the olfactory bulb transform overlapping sensory inputs into representations that are easier to distinguish? New study by Sina Tootoonian, Yikai Yang, @andreas-t-schaefer.bsky.social @crick.ac.uk and myself.‬ www.biorxiv.org/content/10.6... A short 🧵 below
biorxiv.org
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Datta Lab @dattalab.bsky.social · 29/04/2026
Excited to see our paper describing a stereotyped receptor map for smell (led by @davidhbrann.bsky.social ) out in the world! See below for short thread with open access link to paper www.nytimes.com/2026/04/29/s...
nytimes.com
Scientists Unveil ‘Long Lost’ Map for Smell
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PLOS Biology @plosbiology.org · 13/04/2026
How do experiences reshape our internal representations of the world? @bstaresina.bsky.social &co show that learning sequential experiences reshapes how the #brain represents what we see; a post-learning nap strengthens these predictive changes @plosbiology.org 🧪 plos.io/4dJGwMC
Emergence of Successor Representations and Experimental Design. Top: Example of how sequence learning and sleep might change neural representations. Upon encountering a Welsh Corgi, the brain primarily represents the current stimulus entity. If the Corgi is part of a recurring temporal sequence (Corgi → Girl → House), subsequent stimuli (Girl and House) might be integrated into the Corgi representation. Post-learning sleep might provide an opportunity for the brain to replay learned experiences and thereby further strengthen successor representations. Upon post-sleep exposure to a Corgi image (right), brain activation patterns might reflect both the current stimulus (Corgi) as well as learned successors (Girl, House). Faded images indicate weaker representations. Middle: Timeline of the experiment. Participants first completed a perceptual task, followed by a sequence learning task (Memory Arena). Memory for the learned sequence was then assessed both before and after a period of sleep. Finally, participants completed the perceptual task again. Bottom left: Memory Arena sequence design. Participants (N = 26) were tasked with learning the spatiotemporal structure of 50 images. These images belonged to five distinct categories (letter strings, scenes, objects, faces, and body parts) and were organized into 10 subsequences of five images each, following one of two fixed category orders: (i) letter string, scene, object, face, or (ii) object, scene, letter string, face, with body part images randomly inserted to obscure the primary category sequences. The two subsequence types were counterbalanced across participants. Bottom right: Memory Arena location design. The Arena was spatially organized into five principal ‘slices’, with each slice corresponding to one of the five main image categories.
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 02/04/2026
Decomposing representational drift across wake and sleep www.biorxiv.org/content/10.64898/20…
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 31/03/2026
Sleep ripples drive single-neuron reactivation for human memory consolidation www.biorxiv.org/content/10.64898/20…
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Marcel S. Kehl @mskehl.bsky.social · 31/03/2026
🔔PREPRINT: Sleep ripples drive single-neuron reactivation for human memory consolidation 1/9: How does sleep support human memory consolidation? To test this, we recorded hundreds of neurons in the human medial temporal lobe (MTL) across learning, wakefulness, and sleep. doi.org/10.64898/202...
doi.org
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Tobias Ackels @tobiasackels.bsky.social · 22/02/2026
One week left to apply!
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 14/02/2026
A learning-evoked slow-oscillatory architecture paces population activity for offline reactivation across the human medial temporal lobe www.biorxiv.org/content/10.64898/20…
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lucakaemmer.bsky.social @lucakaemmer.bsky.social · 26/01/2026
Finally out in eLife!! "Early foveal cortex predicts the features of saccade targets through feedback from higher cortical areas." elifesciences.org/articles/107...
elifesciences.org
Feedback of peripheral saccade targets to early foveal cortex
Low-level features of peripheral saccade targets are fed back to early foveal retinotopic cortex in a signal that resembles activation elicited by direct foveal presentation.
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Bernhard Staresina @bstaresina.bsky.social · 19/01/2026
Last week to apply! Cognitive Neuroscience Research Laboratory Manager at @oxexppsy.bsky.social (with links to @oxcin.bsky.social and @ox.ac.uk) www.jobs.ac.uk/job/DPZ833/c...
jobs.ac.uk
Cognitive Neuroscience Research Laboratory Manager at University of Oxford
Check out jobs.ac.uk for opportunities in professional services, including Cognitive Neuroscience Research Laboratory Manager. Apply today and learn more about the role.
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Fabian Schwimmbeck @fabian31415.bsky.social · 18/01/2026
How are memories consolidated during sleep? Excited to share another preprint: hippocampal SWRs route memory content to the cortex via interregional co-reactivation of concept cells, optimized by slow-oscillation–spindle coupling. With the great @tschreiner.bsky.social @humansingleneuron.bsky.social
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Nature @nature.com · 13/01/2026
Nature research paper: Distinct neuronal populations in the human brain combine content and context go.nature.com/4jCecge
go.nature.com
Distinct neuronal populations in the human brain combine content and context - Nature
Single-neuron recordings in humans reveal largely separate content and context neurons whose coordinated activity flexibly places memory items in context.
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Liset M. de la Prida @lmprida.bsky.social · 18/12/2025
What is a 🧠 ripple? See our @cellpress.bsky.social perspective on ripple diversity and the grammar of memory replay: connecting key pieces from current work across the field. 👉🏼 www.sciencedirect.com:5037/science/arti...
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Esteban @estebanbt.bsky.social · 04/12/2025
I'm happy to share my debut as first-author with the recent publication of our article in #JNeurosci: www.jneurosci.org/content/earl... Big thanks again to @tschreiner.bsky.social and the whole team who made this possible! 🧠🌬️
jneurosci.org
Respiration shapes the neural dynamics of successful remembering in humans.
Respiration has been shown to impact memory retrieval, yet the neural dynamics underlying this effect remain unclear. Here, we investigated how respiration shapes both behavioral and neural expression...
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Bernhard Staresina @bstaresina.bsky.social · 24/11/2025
Well done Pin-Chun! Thanks also to @oxexppsy.bsky.social, @oxcin.bsky.social, and @erc.europa.eu
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Alana Darcher @alanadarcher.bsky.social · 14/11/2025
How is the semantic content of a movie processed by our brains? 🧠🎬 We decode characters, events, & other features and investigate how populations and single neurons represent movie features. Check my poster @sfn.org #sfn25! Sat. Nov 15, 6:45-8:45pm, Hall E, poster S5 Wed. Nov 19, 9-10am, poster NN5
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Randolph Helfrich @randolph-helfrich.bsky.social · 10/11/2025
New work from the lab published in @cp-neuron.bsky.social by @jonasterlau.bsky.social and Jan Martini. We describe that trial-by-trial variability indexes recurrent connectivity across the cortical hierarchy, which supports reliable and flexible coding www.cell.com/neuron/abstr... (1/4)
cell.com
Structure in noise: Recurrent connectivity shapes neural variability to balance perceptual and cognitive demands in the human brain
Does neural variability reflect random noise or a feature that benefits adaptive behavior? Using intracranial recordings in humans, Terlau et al. demonstrate that neural variability results from the r...
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Yvonne Chen @yvonnechen.bsky.social · 05/11/2025
My Lab @unlv.edu is recruiting motivated students interested in human memory and brain research! Learn #EEG, #fMRI, and data analysis while exploring how we remember 🧠 📧 DM me or check out #PhD program www.unlv.edu/degree/phd-n... & www.unlv.edu/psychology/g... Plus, Vegas is a fun place to live!🤟
unlv.edu
Doctor of Philosophy - Neuroscience
This interdisciplinary Ph.D. program provides coursework and research training in neuroscience, with research mentoring spanning a range of different dimensions (basic to applied/clinical neuroscience...
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Martin Hebart @martinhebart.bsky.social · 04/11/2025
Please repost! I am looking for a PhD candidate in the area of Computational Cognitive Neuroscience to start in early 2026. The position is funded as part of the Excellence Cluster "The Adaptive Mind" at @jlugiessen.bsky.social. Please apply here until Nov 25: www.uni-giessen.de/de/ueber-uns...
View from your office onto Giessen and surrounding villages.
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Marcel S. Kehl @mskehl.bsky.social · 27/10/2025
🚨Preprint: Semantic Tuning of Single Neurons in the Human Medial Temporal Lobe 1/8: How do human neurons encode meaning? In this work, led by Katharina Karkowski, we recorded hundreds of human MTL neurons to study semantic coding in the human brain: doi.org/10.1101/2025...
doi.org
Semantic Tuning of Single Neurons in the Human Medial Temporal Lobe
The Medial Temporal Lobe (MTL) is key to human cognition, supporting memory, emotional processing, navigation, and semantic coding. Rare direct human MTL recordings revealed concept cells, which were ...
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 27/10/2025
Semantic Tuning of Single Neurons in the Human Medial Temporal Lobe www.biorxiv.org/content/10.1101/202…
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 22/08/2025
Hippocampal stimulation reveals causal role of persistent neural activity in human working memory www.biorxiv.org/content/10.1101/202…
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Tim Guth @timaguth.bsky.social · 11/08/2025
Excited to share our new paper on theta-phase locking of single neurons during human spatial memory: www.nature.com/articles/s41... With @lukaskunz.bsky.social, Joshua Jacobs, and our colleagues from the University of Freiburg
Neuronal theta-phase locking increased during periods of elevated theta power, when aperiodic activity exhibited steeper slopes, and when clear theta oscillations were detected. Theta-phase locking was similarly strong during the successful and unsuccessful encoding and retrieval of memories. Some neurons changed their preferred theta phases between encoding and retrieval.
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Olivia Christiano @oliviachristiano.bsky.social · 19/07/2025
How reliable is OPM-MEG, and how does it compare to other neuroimaging modalities? 🤔 In a new preprint with ‪@s-michelmann.bsky.social‬, we evaluate the reliability of OPM-MEG within & between individuals, and compare it to fMRI & iEEG during repeated movie viewing. 🧠 📄 doi.org/10.1101/2025...
doi.org
Reliability and signal comparison of OPM-MEG, fMRI & iEEG in a repeated movie viewing paradigm
Optically pumped magnetometers (OPMs) offer a promising advancement in noninvasive neuroimaging via magnetoencephalography (MEG), but establishing their reliability and comparability to existing metho...
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Nature Human Behaviour @nathumbehav.nature.com · 09/07/2025
In this Article, Paluch et al. show that unattended working memory items, as well as attended ones, are encoded in persistent activity in the medial temporal lobe. @jankaminski.bsky.social www.nature.com/articles/s41...
nature.com
Unattended working memory items are coded by persistent activity in human medial temporal lobe neurons - Nature Human Behaviour
Paluch et al. show that unattended working memory items, as well as attended ones, are encoded in persistent activity in the medial temporal lobe.
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Martin Hebart @martinhebart.bsky.social · 23/06/2025
What makes humans similar or different to AI? In a paper out in @natmachintell.nature.com led by @florianmahner.bsky.social & @lukasmut.bsky.social, w/ Umut Güclü, we took a deep look at the factors underlying their representational alignment, with surprising results. www.nature.com/articles/s42...
nature.com
Dimensions underlying the representational alignment of deep neural networks with humans - Nature Machine Intelligence
An interpretability framework that compares how humans and deep neural networks process images has been presented. Their findings reveal that, unlike humans, deep neural networks focus more on visual ...
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Xianhui He @xianhuihe.bsky.social · 16/06/2025
How does our brain learn that thunder follows lightning? We don't just remember two separate events; we build a predictive model to anticipate the world. My research dives into this very question: how we learn and predict the order of events. 🧵👇 1/9 #neuroscience #memory #sleep
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Marcel S. Kehl @mskehl.bsky.social · 16/06/2025
How does sequence learning reshape item representations? We found that the brain incorporates high-level successor representations even outside the sequence task. This process is supported by slow-wave sleep. Great work by @xianhuihe.bsky.social and the team! www.biorxiv.org/content/10.1...
biorxiv.org
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 16/06/2025
Sleep strengthens successor representations of learned sequences www.biorxiv.org/content/10.1101/202…
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Brice Bathellier @bathellierlab.bsky.social · 15/06/2025
New study of the lab showing that sleep preserve sound representations geometry in the auditory cortex but intermittently blocks the transfer of sensory information, possibly to provide both opportunities for surveillance and offline processing. www.biorxiv.org/content/10.1...
biorxiv.org
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Thomas Schreiner @tschreiner.bsky.social · 09/06/2025
Born from a collaboration with @danlikesbrains.bsky.social ’s team, this project shows how your breathing shapes brain excitability across the entire wake–sleep cycle. Huge shoutout to everyone involved — go check it out! 💥 #neuroskyence
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Katrijn Schruers @katschruers.bsky.social · 21/05/2025
Just published my first paper! Really grateful to everyone at the plasticity lab @oxcin.bsky.social who made this possible. huge thanks to my co-authors — couldn’t have done it without you. If you want to check it out: 📄 paper: www.nature.com/articles/s41...
nature.com
Sleep regularity index as a novel indicator of sleep disturbance in stroke survivors: a secondary data analysis - Scientific Reports
Scientific Reports - Sleep regularity index as a novel indicator of sleep disturbance in stroke survivors: a secondary data analysis
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Tobias Ackels @tobiasackels.bsky.social · 18/05/2025
🚨 Preprint alert! 🚨 Can mice estimate the distance to an odour source? New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself. Spoiler alert: Yes, they can! Read the paper here: bit.ly/43A9tF9 Short 🧵 below
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Tamara Gedankien @gedankien.bsky.social · 14/05/2025
Hi Bluesky! First post here. Kicking things off with a new preprint. 🧠 Using human iEEG + pharmacology, we asked: is hippocampal theta required for retrieval? Turns out it’s not. Instead, it may reflect a reinstated encoding mode. Thread below. www.biorxiv.org/content/10.1...
biorxiv.org
Cholinergic blockade reveals role for human hippocampal theta in encoding but not retrieval
Cholinergic dysfunction is a hallmark of Alzheimer's disease and other memory disorders. Yet, the neurophysiological mechanisms linking cholinergic signaling to memory remain poorly understood. In thi...
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Bernhard Staresina @bstaresina.bsky.social · 29/04/2025
New paper out in SLEEP @sleepjournals.bsky.social! In his study, Jude Thom shows how cortical regions excited by tDCS before sleep express more spindles during subsequent sleep. doi.org/10.1093/slee... @oxexppsy.bsky.social @oxcin.bsky.social @ukri.org
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Esteban @estebanbt.bsky.social · 24/04/2025
Very excited to share the first preprint of my PhD thesis! Together with @tschreiner.bsky.social, we investigated how respiration coordinates signature neural expressions of successful remembering during memory retrieval. 🫁🧠 🧵(1/8)
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Marc Spehr @marcspehr.bsky.social · 22/04/2025
www.jneurosci.org/content/45/1... Excited to see this out (now in print). A fantastic collaboration by former student Rudolf Degen and current PhD student Victoria Switacz, who did an amazing job closing the deal on this one. Give it a read if you like, but beware - it's nerdy ephys at its best.
jneurosci.org
Ca2+-Activated Ion Channels Exert Opposite Effects in Different Signaling Compartments of Vomeronasal Sensory Neurons
In most mammals, conspecific chemical cues that drive innate social and sexual behavior are detected by the vomeronasal organ (VNO) and processed in the accessory olfactory bulb (AOB). Chemosensory st...
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Adrien Peyrache @apeyrache.bsky.social · 14/04/2025
🚨new paper alert Blind mice use stereo olfaction, comparing smells between nostrils, to maintain a stable sense of direction. Blocking this ability disrupts their internal compass. Kudos to @kasumbisa.bsky.social! Another cool chapter of the Trenholm-Peyrache collab😉 www.nature.com/articles/s41...
nature.com
Stereo olfaction underlies stable coding of head direction in blind mice - Nature Communications
Stereo olfaction involves comparing odor differences between the two nostrils. Here, using neuronal recordings and a behavioral test, the authors demonstrate that blind mice use stereo olfaction to fo...
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Daniel S. Kluger @danlikesbrains.bsky.social · 11/04/2025
Great and comprehensive review by Adriano Tort and colleagues on respiratory involvement in both rodent and human brain activity. Can't help but be intrigued by the complexities of time scales, mechanisms, and behavioural relevance. Long and exciting road ahead. 🧠🟦 www.nature.com/articles/s41...
nature.com
Global coordination of brain activity by the breathing cycle - Nature Reviews Neuroscience
Synchrony between neuronal activity and the respiratory cycle has been observed in numerous brain regions and across many species. Tort et al. discuss the mechanisms by which brain activity is modulat...
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