Reposted by Vishal MohanakrishnanEVBO @evborg.bsky.social · 23/06/2026EVBO congratulates our board members, Katrien de Bock and Taija Mäkinen, on receiving their ERC Advanced Grants! 0123
Reposted by Vishal Mohanakrishnanpipsasaharinen.bsky.social @pipsasaharinen.bsky.social · 15/06/2026Glad to see @jci.org featuring our study on endothelial RTK/integrin crosstalk—where ANGPT2 simultaneously engages two receptors! Big thanks to @johannaivaska@bsky.social and all co-authors and funders. @HelsinkiUniMed @helsinkiuni doi.org/10.1172/JCI1... #vascularbiologydoi.org JCI - Inactive β1-integrin acts as a junctional scaffold for angiopoietin/TIE2/FOXO1 signaling 063
Reposted by Vishal MohanakrishnanOndine Cleaver @ondinecleaver.bsky.social · 28/05/2026Calling all vascular biologists! Join us for cutting edge science at #Angioscience26 in gorgeous Seeon, Bavaria. Awesome speakers, intimate setting, many talks from abstracts. Deadline June 15th to register! vwfb.de/start/regist... 0169
Reposted by Vishal MohanakrishnanJournal of Experimental Medicine @jem.org · 01/06/2026Irena Roci et al. @petrovalab.bsky.social show that the water channel AQP1 sustains lymphatic endothelial cell migration under osmotic stress, establishing tissue #osmolarity as a key biophysical determinant of postnatal #lymphangiogenesis. rupress.org/jem/article/... #lymphatics #AQP1 072
Reposted by Vishal MohanakrishnanHans schoofs @hansschoofs.bsky.social · 18/05/2026Happy to share that our latest work on VEGFR2 in lymphatic endothelium is published @natcomms.nature.com “VEGFR2 is required for VEGF-C–VEGFR3–PI3Kα-mediated sprouting lymphangiogenesis” tinyurl.com/47bns9pp This project has been a long journey for the lab @taijamakinenlab.bsky.social , A thread. 1249
Reposted by Vishal MohanakrishnanMax Planck Institute for Molecular Biomedicine @mpi-muenster.bsky.social · 04/03/2026We are offering 5 Postdoc Positions within the Max Planck Postdoc Program! Take advantage and apply by April 13, 2026 to the positions in the labs of @ralfhadams.bsky.social, @ruibenedito.bsky.social and @katemiro.bsky.social. Link to our website: www.mpi-muenster.mpg.de/max-planck-p... 186
Reposted by Vishal MohanakrishnanMax-Planck-Gesellschaft @maxplanck.de · 02/03/2026The Max Planck #PostdocProgram offers top emerging talents a range of attractive measures and opportunities. The current call for applications is open from March 1st until April 13th, 2026. Please share or consider applying! 🙏 www.mpg.de/en/max-planc... #careerinscience #sciencecareer 04438
Reposted by Vishal MohanakrishnanNature @nature.com · 22/02/2026Veins in the skull can rearrange their borders to accommodate patrolling immune cells go.nature.com/4tLrKulgo.nature.comHow ‘skull drains’ keep the brain safe from damage and pathogensNature - Veins in the skull can rearrange their borders to accommodate patrolling immune cells, a strange behaviour called ruffling. 05312
Reposted by Vishal MohanakrishnanEVBO @evborg.bsky.social · 09/02/2026Job alert: eur04.safelinks.protection.outlook.com?url=https%3A...eur04.safelinks.protection.outlook.comPostdoctoral and doctoral positions to study Immune–Endothelial Interfaces - European Vascular Biology OrganisationPostdoctoral and Doctoral positions are available in the newly established Finnish Centre of Excellence in Immune–Endothelial Interfaces (IMMENs), composed of four research groups: Dr. Taija… 033
Reposted by Vishal MohanakrishnanMakinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · 22/01/2026Thrilled to kick off our Centre of Excellence on Immune–Endothelial Interfaces (IMMENs), funded by the Research Council of Finland, with the first meeting in Helsinki! Great to start this journey with Kari Vaahtomeri, Cecilia Sahlgren and Guillaume Jacquemet @guijacquemet.bsky.social. 1374
Reposted by Vishal MohanakrishnanPetrova Lab – Vascular and Tumor Biology @petrovalab.bsky.social · 22/01/2026Our new study is out! 🎉 Driven by MD‑PhD Ludivine Bersier, our work shows how chemotherapy‑induced gut injury creates a systemic “chemomemory” that protects against colorectal cancer (CRC) liver metastasis. 🔗 doi.org/10.1038/s414... 🧵 Thread 👇 1123
Reposted by Vishal MohanakrishnanBen Hogan @benjhogan.bsky.social · 21/01/2026We’re delighted to see this out today! Latest work from the lab reveals insights into the evolution of brain immunity and the developmental and evolutionary plasticity of lymphatic endothelial cells. www.nature.com/articles/s41...nature.comConvergent evolution of scavenger cell development at brain borders - NatureTranscription factor osr2 is identified as a specific marker and regulator of mural lymphatic endothelial cell (muLEC) differentiation and maintenance, and muLECs and border-associated macrophages sha... 137625
Reposted by Vishal MohanakrishnanEMBO @embo.org · 11/10/2025We have asked the new EMBO Members to tell us about themselves and what makes it so compelling to work in #science today. 🧪 In the eighth video of the series, EMBO Members tell us what part of their #research process they enjoy the most and why. #LifeSciences 0104
Reposted by Vishal MohanakrishnanNature Cardiovascular Research @natcardiovascres.nature.com · 15/07/2025❤️Our July issue is out❤️Discover an Angiopoietin-TIE2-dependent circuit promoting venous malformations, complex disease modelling in cardiac organoids, regulation of cardiac homeostasis by methyonil tRNA synthetase, and more! www.nature.com/natcardiovas... 0115
Reposted by Vishal MohanakrishnanMakinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · 01/07/2025I am honoured to be elected as a Member of EMBO and look forward to contributing to its mission and community! 5214
Reposted by Vishal MohanakrishnanMakinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · 25/05/2025Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations. Read our work in @natcardiovascres.nature.com by Marle Kraft et al. rdcu.be/enhSTrdcu.beAngiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformationsNature Cardiovascular Research - Kraft et al. identify TIE2 activation as a key driver of PIK3CA-related venous malformations and demonstrate that inhibiting TIE2 signaling can suppress the growth... 1198
Reposted by Vishal MohanakrishnanKarina Yaniv @karinayaniv.bsky.social · 25/03/2025📢 #GRC_Angiogenesis program is up! We have an amazing lineup of speakers ready to dive into the "social life" of vessels! How they engage with their neighbors, how they connect, and why they break up! Plus we have ~15 slots available for short talks! Apply (link 👇) and see you in Newport in July! 12115
Reposted by Vishal MohanakrishnanHao Yin @haoyin.bsky.social · 21/03/2025Not every organ ages the same🤠 With Age, Skull bone marrow Vasculature+HSPC Expand & ⏫ contribution to peripheral leukocyte Skull BM expands with Pregnancy CML PTH Stroke @bikohcello.bsky.social @vishalmkrishnan.bsky.social @ralfhadams.bsky.social @nature.com 2024 www.nature.com/articles/s41... 0164
Vishal Mohanakrishnan @vishalmkrishnan.bsky.social · 20/03/2025I am a bit biased, but check out the beautiful work and thread by @hansschoofs.bsky.social @taijamakinenlab.bsky.social on why lymphatic endothelial cells have their jigsaw puzzle-like shape 😍😍😍 051
Reposted by Vishal MohanakrishnanSara Wickstrom @sarawickstrom.bsky.social · 15/02/2025My lab at the Max Planck Institute for Molecular Biomedicine in Muenster, Germany offers postdoc positions in stem cell mechanobiology. www.mpi-muenster.mpg.de/departments/... drop me an emailmpi-muenster.mpg.deCell and Tissue Dynamics (Wickström) 08064
Reposted by Vishal MohanakrishnanEVBO @evborg.bsky.social · 04/02/2025#EVBOSummerSchool 2025: Please help spread the news! 10-11 June 2025 | Biomedicum Helsinki, Finland Registration will open soon. Stay tuned! The summer school will be preceded by the excellent and free-of-charge Wihuri Research Symposium on Cardiovascular Biology! More info buff.ly/42I9fvY 077
Reposted by Vishal MohanakrishnanHao Yin @haoyin.bsky.social · 31/01/2025Type R capillary #EndothelialCell in Bone Cav1+ Efnb2+Flt4-Emcn+ B/w Sinusoid EC & Artery 👉Close to trabecular🦴 osteoprogenitor osteoclast 👉Angiocrine SEMA7A+ ⏫by #Aging anti-osteoporosis therapy @vishalmkrishnan.bsky.social l @ralfhadams.bsky.social #NatCellBio 2024 www.nature.com/articles/s41... 243
Reposted by Vishal MohanakrishnanNature @nature.com · 13/01/2025Blood vessels in the brain rhythmically constrict and dilate to drive waves of cleansing fluid through the organ go.nature.com/3PwtwN2go.nature.comHow the brain cleans itself during deep sleepBlood vessels in the brain rhythmically constrict and dilate to drive waves of cleansing fluid through the organ. 07924
Reposted by Vishal MohanakrishnanGeert Carmeliet @geertlab.bsky.social · 13/01/2025Big congratulations to Shauni Loopmans for her excellent PhD research, now online in @natmetabolism.bsky.social. This study reveals that the pentose phosphate pathway in #chondrocytes is crucial for ER redox homeostasis and cell survival rdcu.be/d5Q65 (1/3)rdcu.beThe pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytesNature Metabolism - Loopmans et al. show that the pentose phosphate pathway in chondrocytes provides reducing power to ensure proteostasis necessary for bone lengthening. 35212
Reposted by Vishal MohanakrishnanStylianos Lefkopoulos (he/him) @slefkopoulos.bsky.social · 31/12/2024Aaaaand finally: #NCB2024 In November, @ralfhadams.bsky.social & co identified a distinct subset of post-arterial #capillaries, termed type R, which contribute to trabecular #bone formation in the diaphysis and respond to anti-#osteoporosis treatments. www.nature.com/articles/s41...nature.comSpecialized post-arterial capillaries facilitate adult bone remodelling - Nature Cell BiologyMohanakrishnan et al. identify a distinct subset of post-arterial capillaries, termed type R. They show that type R capillaries contribute to trabecular bone formation in the diaphysis and respond to ... 0102
Reposted by Vishal MohanakrishnanOndine Cleaver @ondinecleaver.bsky.social · 02/12/2024Pleased to share the work of Mitzy Cowdin and others in our lab showing the requirement for the Hippo pathway kinases Lats1 and 2 for endothelial sensing of hemodynamic flow and for vascular remodeling during embryogenesis 🎉🧪 www.biorxiv.org/content/10.1...biorxiv.orgLats1/2 are essential for developmental vascular remodeling and biomechanical adaptation to shear stressBlood vessels in mammalian embryos develop from initial aggregates of endothelial cell (EC) progenitors, which coordinate the opening and stabilization of central vascular lumens, all while under prog... 35019
Reposted by Vishal MohanakrishnanJohanna Joyce @johannajoyce.bsky.social · 25/11/2024Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve #gender #equality? We discuss various strategies in this #Cell Commentary #WomeninSTEM www.cell.com/cell/fulltex... 🧵 1/ 361192596
Reposted by Vishal MohanakrishnanStylianos Lefkopoulos (he/him) @slefkopoulos.bsky.social · 23/11/2024🥂Congratulations to @ralfhadams.bsky.social @vishalmkrishnan.bsky.social & co for their new Open Access study in our journal (@naturecellbiology.bsky.social) identifying type R #capillaries and showing their role in trabecular #bone formation in the diaphysis. www.nature.com/articles/s41...nature.comSpecialized post-arterial capillaries facilitate adult bone remodelling - Nature Cell BiologyMohanakrishnan et al. identify a distinct subset of post-arterial capillaries, termed type R. They show that type R capillaries contribute to trabecular bone formation in the diaphysis and respond to ... 1142
Reposted by Vishal MohanakrishnanNature Cell Biology @natcellbio.nature.com · 21/11/2024💫NEW: @ralfhadams.bsky.social & co identify a distinct subset of post-arterial #capillaries, termed type R. They show that type R capillaries contribute to trabecular #bone formation in the diaphysis and respond to anti- #osteoporosis treatments. www.nature.com/articles/s41...nature.comSpecialized post-arterial capillaries facilitate adult bone remodelling - Nature Cell BiologyMohanakrishnan et al. identify a distinct subset of post-arterial capillaries, termed type R. They show that type R capillaries contribute to trabecular bone formation in the diaphysis and respond to ... 0183
Vishal Mohanakrishnan @vishalmkrishnan.bsky.social · 19/11/2024Bone remodeling is traditionally driven by osteoblasts and osteoclasts, but our study reveals a third essential player: "Type R capillaries". 🦴🔬😍 Excited to share my PhD work from Ralf H. Adams lab, now published in @natureportfolio.bsky.social Nature Cell Biology. www.nature.com/articles/s41... 1348
Reposted by Vishal MohanakrishnanSébastien Gauvrit @sebgauvrit.bsky.social · 18/11/2024Here's a starter pack focusing on cardiovascular research. I'm sure the pack is incomplete. If you'd like to be added to the list, please let me know! go.bsky.app/SgaGkv5 263019