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Lynda Coughlan

@virusnerdette.bsky.social
845 followers 824 following 28 posts

Irish virologist/vaccinologist @UMmedschool @UMCVD, Associate Prof, viruses, adenoviral vectors, influenza, vaccines, immunology, scicomm, STEM

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Reposted by Lynda Coughlan
Alex Guseman @alexguseman.bsky.social · 21/08/2026
Come be my colleague! We are hiring a structural biologist. I have thoroughly enjoyed starting my career here and both department(s) are full of exceptional scientists. apol-recruit.ucsd.edu/JPF04589
apol-recruit.ucsd.edu
Assistant Professor in Structural Biochemistry
University of California, San Diego is hiring. Apply now!
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Alex Guseman @alexguseman.bsky.social · 11/08/2026
Im looking for a postdoc to help with protein engineering efforts. If you know who could be a good fit send them my way! see details below:
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Reposted by Lynda Coughlan
Nature @nature.com · 20/08/2026
The US National Science Foundation will award about 30% fewer new research grants this fiscal year than in the last one, Nature has learnt. go.nature.com/3UcGoNW
go.nature.com
Exclusive: NSF set to issue lowest number of new grants in four decades
The US science-funding agency is withholding $1 billion of its budget so that the money can go to a special White House project.
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Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 29/06/2026
There is no excuse for Bill Cassidy voting to confirm RFK Jr. and convincing others to do so. Tens of thousands of expert healthcare professionals and scientists opposed this, and he ignored us because he thought it would benefit him. Now he wants to wash his hands. But we will NEVER forget.
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Dan Baldassarre @evornithology.bsky.social · 21/06/2026
Brutal grant-witness.us/posts/2026-0...
grant-witness.us
The NSF is on Track for its Worst Year in Generations – Grant Witness
Throttling of science funding is utterly unprecedented and radical when compared to the past 50 years.
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 03/06/2026
I have often been critical of the leadership @aaas.org but they just took action on the new OMB rules that will politicize science, speaking out and notifying members. I hope all take the time to follow their advice, contact Congress, and most important, post a comment www.aaas.org/news/aaas-st...
Dear Mark,

Yesterday, AAAS spoke out against a damaging proposal from the U.S. Office of Management and Budget (OMB) that would jeopardize future scientific discoveries and breakthroughs by bringing politics into the heart of scientific evaluation and priority setting and rejecting the will of Congress and the American people.

The proposed rule forgets what has made America the world’s R&D leader for generations. Among many bad policy choices, the most damaging is that it would prioritize politics over merit by enabling OMB budget analysts to override scientific peer review to decide what science is worth funding. If this rule is implemented, Americans' hopes for future cures, national security, and economic strength will rely on the scientific sensibilities of the Director of OMB, the nation’s chief bureaucrat. We must speak out against this with all of our voices.

You can find my full statement here and an editorial from Science Editor-in-Chief Holden Thorp here. For further details on the proposed rule, read the ScienceInsider article.

The proposed rule is laid out over more than 400 pages. The public comment period is open until July 13 and it will take some time to fully assess the rule’s possible impacts. AAAS is already working to prepare a thoughtful, strong, and strategic official comment to OMB. In addition, we are putting all of our resources to work in public and behind the scenes to push back on this outrageous overreach.

The process for rulemaking gives all of us an opportunity to comment in the regulatory process and speak up in the political process. Here are three valuable actions for you to take:

Let your representatives in Congress know that this proposed rule is bad for everyone – not just scientists. Tell them your concerns about putting political appointees who lack the necessary expertise in charge of science and research funding decisions and the potential impact on our hopes for future cures, national security, and American jobs.
Respo…
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J. Craig Venter Institute @jcvi.org · 30/04/2026
It is with great sadness that we announce J. Craig Venter has died. 🧪🧬 www.jcvi.org/media-center...
jcvi.org
J. Craig Venter, genomics pioneer and founder of JCVI and Diploid Genomics, Inc., dies at 79
La Jolla, California—April 29, 2026—The J. Craig Venter Institute (JCVI) announced that J. Craig Venter, Ph.D., the Institute’s founder, board...
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Jenna Norton @jenna-m-norton.bsky.social · 30/04/2026
Sharing this screen grab from a friend at NIH (with permission). This is a checklist program officers have to complete before a grant can be awarded. The first question: "Is this grant All Clean/Clear in the NIH Text analysis Tool?" 🧵1/3
Screen grab of an NIH grants checklist showing the first question is: "1. Is this grant All Clean/Clear in the NIH Text analysis Tool?"
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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 29/04/2026
"I suspect that the scientists who complain about 40% of their time taken up with non-science tasks are referring to the grant chase. The amount of time devoted to writing and submitting grant after grant after grant...The strangling of scientific productivity is because of the grant chase."
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Helen Branswell 🇨🇦 @helenbranswell.bsky.social · 25/04/2026
The world of influenza science has lost one of its giants. Nancy Cox, who led #CDC's flu division for years & worked assiduously to improve global flu surveillance, died Thursday. I learned a ton from Nancy Cox. RIP. www.statnews.com/2026/04/25/n...
statnews.com
Nancy Cox, a CDC veteran and a stalwart in global flu research, dies at 77
Nancy Cox, a CDC veteran who for decades was a global leader in influenza research, has died at 77.
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Jenna Norton @jenna-m-norton.bsky.social · 22/04/2026
NIH is not okay. @nytimes.com highlights how grant-making & ability to obligate funding is at risk from staff shortages and time consuming screening processes designed to censor research to align with the administration's political ideology. www.nytimes.com/2026/04/22/s... Some highlights:
nytimes.com
Pace of N.I.H. Funding Slows Further in Trump’s Second Year
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Joshua Weitz @joshuasweitz.bsky.social · 22/04/2026
The review and award process is also subject to new constraints. For example: multiyear funding has reduced award rates significantly, such that more labs face funding cliffs that could lead to permanent lab closing and an accelerated brain drain. substack.com/home/post/p-...
substack.com
Moving the Goalposts at NIH
NIH funding data reveals dramatic shifts in award rates last year even for highly ranked proposals – yet another warning sign for the state of American science.
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Joshua Weitz @joshuasweitz.bsky.social · 22/04/2026
Despite Congress' rejection of the FY 2026 budget, scientists and institutions are increasingly under threat as ideology rather than evidence shapes funding and policy decisions for science and medical research. bsky.app/profile/lena...
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Joshua Weitz @joshuasweitz.bsky.social · 22/04/2026
Today, our #SCIMaP team released an impact analysis of the White House proposed FY 2027 NIH and NSF budgets. Bottom-line: if enacted, cuts to science and medical research would lead to $35B in economic losses and 150,000 lost jobs in communities all across the US. scienceimpacts.org 🧵
Landing page for scienceimpacts.org
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c0nc0rdance @c0nc0rdance.bsky.social · 11/02/2024
It's International Women in Science Day ♀️, and I want to talk briefly about Rosalind Franklin. A conventional choice for unconventional reasons: Dr. Franklin was one of the FIRST STRUCTURAL VIROLOGISTS. Let's talk about her work outside of the Crick & Watson debacle.
Rosalind Elsie Franklin was an English chemist and X-ray crystallographer whose work was central to the understanding of the molecular structures of DNA (deoxyribonucleic acid), RNA (ribonucleic acid), viruses, coal, and graphite.

Description:  Dr. Franklin looks across a checkered table at everyday objects.  I think this is in a cafe or a breakroom.  Since we know this is Paris, this photo is likely from 1946?With all she did to make Watson and Crick's discovery possible, Rosalind Franklin was essentially "a de facto collaborator," says Lynne Osman Elkin.
Novartis Foundation

Dr. Franklin looks to her right, wearing a dark necklace and broad-yoked shirt or blouse.  She has short dark hair and eyebrows, and has a look of sharp intelligence, with an edge of weariness.
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Jenna Norton @jenna-m-norton.bsky.social · 17/04/2026
This is a handy little website if you want to keep track of how things are going with science funding. sciencespending.org#overview
sciencespending.org
Tracking Science Spending
Track federal science spending at NIH, NSF, DOE, NASA, and USDA. Monitors obligation rates and award activity against historical averages using official budget data.
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Michael Baym @baym.lol · 17/04/2026
I’m looking for an automated way to read others’s scientific data without giving credit or acknowledgement, and also claim full credit for insights from it. And I want it to have a fitting name OAI: say no more
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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 15/04/2026
As a recipient of federal grants from #NIH (for now! 😭) that funds research in my lab, I'd like to sincerely thank American taxpayers on #TaxDay for investing in scientific research that lays the foundation for medical and technological innovation in this country and keeps us ALL safe and healthy
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Jeremy Berg @jeremymberg.bsky.social · 09/04/2026
Some great (but not surprising to me) news! "The Trump administration will not be asking the Supreme Court to take up its fight to slash federal support for funding that the nation’s science enterprise relies on for basic operating costs." www.statnews.com/2026/04/08/t... 1/2
statnews.com
Trump administration drops court fight to cap NIH payments for research overhead costs
The Trump administration will not be asking the Supreme Court to take up its fight to slash NIH support for research indirect costs
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Thelonevirologist @thelonevirologist.bsky.social · 13/03/2026
Polymerase trapping as the mechanism of H5 highly pathogenic avian influenza virus genesis www.science.org/doi/10.1126/...
science.org
Polymerase trapping as the mechanism of H5 highly pathogenic avian influenza virus genesis
Highly pathogenic avian influenza viruses (HPAIVs) derive from H5 and H7 low pathogenic avian influenza viruses (LPAIVs). Although insertion of a furin-cleavable multibasic cleavage site (MBCS) in the...
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Reposted by Lynda Coughlan
Max Kozlov @maxkozlov.bsky.social · 13/03/2026
I got excited when I saw that NIH might have received its first apportionment from OMB today. Alas, it's for ARPA-H. OMB still has not given NIH a dime for non-salary, non-emergency expenses from the spending bill that was signed into law on Feb 3.
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AJ te Velthuis @ajtevelthuis.bsky.social · 12/03/2026
Transient RNA structures play a key role in the emergence of highly pathogenic avian influenza viruses! Great to see this collaboration with Mathis Funk, Mathilde Richard, Stephen Cusack, and others in @science.org www.science.org/doi/10.1126/...
science.org
Polymerase trapping as the mechanism of H5 highly pathogenic avian influenza virus genesis
Highly pathogenic avian influenza viruses (HPAIVs) derive from H5 and H7 low pathogenic avian influenza viruses (LPAIVs). Although insertion of a furin-cleavable multibasic cleavage site (MBCS) in the...
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Reposted by Lynda Coughlan
Alt CDC (they/them) @altcdc.altgov.info · 09/03/2026
💉 Where can you find accurate information on vaccines❓ ✅ American Academy of Pediatrics (AAP): downloads.aap.org/AAP/PDF/AAP-... ✅ Medical societies: cmss.org/programs-and... ✅ CIDRAP for in-depth evidence review: vaxintegrity.cidrap.umn.edu/evidence-rev...
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Jeremy Berg @jeremymberg.bsky.social · 09/03/2026
@joshuasweitz.bsky.social recently posted this graph that shocked but did not surprise me. This graph is based on data recently release by NIH report.nih.gov/nihdatabook/... 2/20
Graph of award probability of R01 from NIH factbook as a function of review rank percentile. Fiscal year 2025 is a significant departure, with lower award probabilities at all scores <40 and significant departures from norm, where even being in the top 10% is no longer a nearly certain indicator of success.
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Joshua Weitz @joshuasweitz.bsky.social · 07/03/2026
The data is in: the NIH goalposts have shifted. What were once almost certain fundable scores have become coin flips and what used to be likely grants have become aspirational, leading to fewer awards. Another manifestation of how HHS policies have led to fewer awards and less science.
Graph of award probability of R35 and R01 from NIH factbook as a function of review rank percentile. As is apparent, 2025 is a significant departure, with lower award probabilities at all scores <40 and significant departures from norm, where even being in the top 10% is no longer a nearly certain indicator of success.

Data source: https://report.nih.gov/nihdatabook/report/302
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Jenna Norton @jenna-m-norton.bsky.social · 20/02/2026
Check this out straight from the NIH website, acknowledging that multiyear funding was likely responsible for a 20% decrease in early stage investigators. And that it was expected. A strange approach for someone so committed to the next generation of scientists. grants.nih.gov/news-events/...
Screenshot from an NIH website reading: "Table 1 shows the number of principal investigators (PIs) applying for or receiving an R01-equivalent grant in FYs 2021 to 2025, disaggregated by career stage. NIH supported 1,423 and 1,144 ESIs in FYs 2024 and 2025, respectively. The decrease seen in FY 2025 may likely be due in part to NIH implementing a requirement to use 50% of its remaining competing Research Project Grant (RPG) funds (starting in June 2025) for full-year funded competing RPGs, which was expected to lead to fewer awards and support fewer researchers overall."
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Jeremy Berg @jeremymberg.bsky.social · 17/02/2026
New and competitive renewal awards. The number of awards is 569 compared with more than 2200 through the same date in earlier fiscal years. All ICs have now made awards except for NIAAA, NCCIH, NLM, FIC, and OD. NEI (Eye Institute) made its first award during the new period. 3/4
A line graph shown the number of NIH new and competitive awards funded for fiscal year 2026 (through 2/13/26) compared with fiscal years 2021-2025. The fiscal year 2026 is lagging well behind with only 569 awards made through 2/13/26 compared to >2000 for previous fiscal years.
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Erik Karlsson @eakarlsson.bsky.social · 11/07/2025
**JOBS ALERT** The Virology Unit at @PasteurCambodia hiring 1 Scientist and 2 Postdocs to join our fast-moving, field-connected, research-driven team on emerging viruses and zoonoses. 🧪🧬🥼🦠🔬🐓💉🦇😷 Limited time to apply — and we need people to start ASAP.**👇
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Erik Karlsson @eakarlsson.bsky.social · 14/02/2026
First human #H5N1 case of 2026 in #Cambodia: a 30-year-old man from Kampot province. Sequencing, virus isolation & animal investigations ongoing. Dead chicken at home before onset. Patient has since recovered. 🦠💉😷🐓🥼🔬🧪 Sequencing, contact tracing, and poultry investigations ongoing.
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Prof Gavin Yamey MD MPH @gavinyamey.bsky.social · 13/02/2026
Right wing chaos agent Jay Bhattacharya strikes again—making the US less prepared for the next pandemic One of the most important national centers for studying infectious diseases, based at the NIH, is no longer allowed to study pandemic preparedness or bio defense😨 www.nature.com/articles/d41...
nature.com
Exclusive: Key US infectious-diseases centre to drop pandemic preparation
Staff members have been instructed to scrub this topic and ‘biodefense’ from the agency’s website.
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Kai Kupferschmidt @kakape.bsky.social · 13/02/2026
“Staff members at the United States’s premier infectious-disease research institute have been instructed to remove the words “biodefense” and “pandemic preparedness” from the institute’s web pages, according to e-mails Nature has obtained.” www.nature.com/articles/d41...
nature.com
Exclusive: Key US infectious-diseases centre to drop pandemic preparation
Staff members have been instructed to scrub this topic and ‘biodefense’ from the agency’s website.
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Prof Sheena Cruickshank @sheencr.bsky.social · 27/01/2026
Moderna have announced that they won't run new phase three trials now with massive impacts for new vaccine development- why- its because of RFK Jr and his anti-vaccine campaigns and cancelling mRNA vaccine research which affect the sales the company can then make 🧪🧵 #PublicHealth
biospace.com
Moderna Won’t Run Phase III Vaccine Trials as Skepticism Grows in US: Bloomberg
Growing opposition to vaccines in the U.S., driven by recent government policy changes, makes it difficult to see a return on investment in vaccine development, Moderna CEO Stéphane Bancel said this w...
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Max Kozlov @maxkozlov.bsky.social · 22/01/2026
🚨 New from me: Grant review at more than half of NIH's institutes could be frozen by the end of the year. That's because crucial NIH grant-review panels are slated to be empty at those institutes by Jan 2027. A wonky bureaucratic problem with big implications. A short 🧵
nature.com
Exclusive: key NIH review panels due to lose all members by the end of 2026
Thirteen of the agency’s advisory councils, which must review grant applications before funding is awarded, are on track to have no voting members.
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Jeremy Berg @jeremymberg.bsky.social · 02/12/2025
New York Times article on science funding with some depressing but familiar curves with interactive graphics. www.nytimes.com/interactive/...
nytimes.com
The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine (Gift Article)
A quiet policy change means the government is making fewer bets on long-term science.
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Drug Monkey @drugmonkey.bsky.social · 24/11/2025
NIH extends the Oct-Nov deadlines to Dec 8, 2025 drugmonkey.wordpress.com/2025/11/24/n...
drugmonkey.wordpress.com
NIH extends the Oct-Nov deadlines to Dec 8, 2025
The NIH has issued a Notice (NOT-OD-26-012) which expands upon the prior warning (NOT-OD-26-005) about extending the current submission deadlines. It seems to be quite comprehensive. All grant appl…
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Monica Bettencourt-Dias @monicabettencourt.bsky.social · 22/11/2025
Last call! Applications for the @crg.eu International PhD Programme 2025 in beautiful Barcelona close next week! Join us and our inspiring colleagues at the CRG - an exceptional environment for discovery, creativity, and scientific growth. Apply here: www.crg.eu/en/content/t...
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BNO News (Health) @health.bnonews.com · 22/11/2025
BREAKING: Man from Washington state dies after being infected with H5N5 bird flu
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Marc Veldhoen @marcveld.bsky.social · 21/11/2025
How does MDPI keep stuffing their journals? By cold emailing random scientists about “special issues” in fields they’ve never worked in, but hey, who needs expertise when the business model is volume? 1/2
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Ed Hutchinson @socialinfluenza.bsky.social · 17/11/2025
If you'd like to celebrate the biology of viruses - or the fight against viral diseases - this winter, try out our free and updated #VirusSnowflake designs. Please share, and if you have any photos of Virus Snowflakes in your area it would be lovely to see them! cvr-engagement.co.uk/virus-snowfl...
A flurry of snowflakes with text reading 'Virus Snowflakes: a collection of paper art viruses by Ed Hutchinson - Download now!' along with the logo of the MRC-University of Glasgow Centre for Virus Research
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Ariane Briegel @arianebriegel.bsky.social · 18/11/2025
Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...
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Drug Monkey @drugmonkey.bsky.social · 15/11/2025
Notes on NIH matters as the government opens up again drugmonkey.wordpress.com/2025/11/14/n...
drugmonkey.wordpress.com
Notes on NIH matters as the government opens up again
A tweet from someone apparently positioned to know claimed the damage totals from the government shutdown amounted to 379 study sections postponed, within which 24,380 NIH grant applications were s…
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Harmit Singh Malik @harmitmalik.bsky.social · 07/11/2025
When people celebrate the individual genius of folks in science, they should also mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)
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c0nc0rdance @c0nc0rdance.bsky.social · 07/11/2025
Her role as one of the first structural virologists is underappreciated.
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The Royal Society @royalsociety.org · 07/11/2025
Born #OnThisDay in 1867 was Marie Skłodowska–Curie, the first woman to win a Nobel Prize, the only woman to win twice and the only person to win a Nobel Prize in two disciplines: Physics for her work on radioactivity, and Chemistry for her discovery of radium and polonium. #WomenInSTEM
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Gregg Gonsalves @gregggonsalves.bsky.social · 02/11/2025
Some charts for those who don't know the extent of the US public (and private) investment in research (particularly in biomedical research) compared to other countries and institutions. The destruction of the US' scientific institutions has global implications.
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Jack Kennedy @jackkennedy.ie · 31/10/2025
No social plans tonight but I might head out onto the balcony in a bit and start screaming "DID YOU KNOW HALLOWEEN IS IRISH ORIGINALLY?" as loud as I can
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Alt CDC (they/them) @altcdc.altgov.info · 29/10/2025
Before October ends, it’s worth reminding folks of the importance of breast cancer screening. Mammograms are recommended for 👻🐝 >40 and folks of all ages with higher risk of breast cancer. Everyone (even you, men!) should do self-examinations ~1x per month.
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Crawford Kilian @crof.bsky.social · 10/10/2025
www.cidrap.umn.edu/avian-influe...
cidrap.umn.edu
Flurry of H5N1 activity noted in commercial poultry, wild birds
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Vaughn Cooper @vscooper.micropopbio.org · 23/09/2025
🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine. 1) MMG (my dept): fundamental research in med micro 2) Peds ID / I4Kids institute 3) Center for Vaccine Research 🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
linkedin.com
Faculty Professor Associate - Full-Time | Vaughn Cooper
We are recruiting Faculty microbiologists in three (3) different, complementary, and collaborative areas at the University of Pittsburgh associated with the School of Medicine. 1) Fundamental researc...
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Lynda Coughlan @virusnerdette.bsky.social · 23/09/2025
Finally got some good grant news last week as Cosette's F31 was awarded (only 5 months after submitting JIT & 10 months after receiving a fundable score 😱). Better late than never I guess! Congrats Cosette, we are super proud of you & thankful to fantastic co-mentors/collaborators🎉
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