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Viejo-Borbolla Lab

@viejoborbolla.bsky.social
41 followers 45 following 25 posts
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 11/10/2025
Back at home after two days of great science in the 18 Mini Herpesvirus Workshop and 1st and only HHV-65 Symposium, celebrating Harmut Hengel’s birthday. @lucasmendesm.bsky.social and @ninaplueckebaum.bsky.social presented exciting results showing how herpesviruses modulate the immune response
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Cell Press @cellpress.bsky.social · 06/10/2025
Congratulations to the 2025 #NobelPrize in Physiology or Medicine winners Drs. Mary Brunkow, Fred Ramsdell, & Shimon Sakaguchi for their discoveries concerning peripheral immune tolerance. View their related research published in #CellPress journals: spkl.io/63325AVK2R
Tile reading "The Nobel Prize in Physiology or Medicine: Read our related articles" Cell Press braned with a NObel Prize medal diplayed on the right hand side.
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AAUP @aaup.org · 06/10/2025
Michel DeGraff, a tenured professor of linguistics at MIT, discusses how his proposal to teach a class on language & decolonization in Haiti, Israel, and Palestine was denied. He faced significant repercussions: he was removed from his department, had a pay raise withheld, and his salary frozen.
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Memorial Sloan Kettering Cancer Center @mskcancercenter.bsky.social · 28/07/2025
New in @natbiotech.nature.com: a team led by scientists at MSK and ‪University of Toronto have developed a new platform to facilitate the study of RNA-biding proteins (RBPs) across hundreds of species of plants, insects, and animals.
nature.com
A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function - Nature Biotechnology
RNA-binding motifs in eukaryotic proteins are presented in a comprehensive resource.
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 03/08/2025
In the last day of the #IHW2025 Josi Schenk funded by @resist-cluster.bsky.social gave a great explanation on how VZV modulates One Carbon metabolism in epithelial cells. Inhibition of this pathway blocked VZV, HSV-1 and HSV-2 infection, providing novel ways to target these viruses
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 29/07/2025
Nina Plückebaum gave a great talk at the #IHW2025 showing the results of a bindings screen performed with the RL11 protein family of #human_cytomegalovirus and 80% of all human single transmembrane proteins revealing a novel viral strategy to modulate natural killer cell activity
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 26/07/2025
Today there were many interesting talks at #IHW2025, including one from Nadine Brückner who gave a great talk in the VZV Satellite Workshop exploring how VZV is repressed during infection of neuron-like cells.
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 25/07/2025
On my way to the #IHW2025 in Berlin. Looking forward to meeting many friends and colleagues and to learn more about herpesviruses
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 28/06/2025
Last Sunday we went hiking in the Deister, nice hills close to Hannover. It was a very nice day despite the heat.
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International Cytokine & Interferon Society (ICIS) @cytokinesociety.bsky.social · 10/06/2025
Don't forget 📆 Abstract deadline for poster or oral presentations is June 18. Please repost to your network to spread the word! More info or register at seattle.cytokinesociety.org
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1kr5ur43m.bsky.social @1kr5ur43m.bsky.social · 03/06/2025
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 23/05/2025
It was a great experience to participate and present our data in the last GRC viruses and cells conference organized by @sesmalab.bsky.social. Looking forward to more exciting science and collaborations!
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 23/05/2025
Wonderful news! This will allow @resist-cluster.bsky.social to better understand why some individuals are highly susceptible to infectious diseases while others aren’t. Thanks to everyone involved in the application and evaluation process!
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 13/05/2025
Don’t miss the @resist-cluster.bsky.social seminar by @richstanton.bsky.social this coming Thursday!
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Exzellenzcluster RESIST @resist-cluster.bsky.social · 08/05/2025
We are very much looking forward to the two lectures on Wednesday (!), 14 May from 12.30 pm by Prof. Donna Neumann and Prof. Robert Kaletja, University of Wisconsin-Madison. Come in large numbers to lecture hall Q at the MHH! We will offer snacks at 12.00 PM www.resist-cluster.de/en/veranstal...
resist-cluster.de
RESIST Seminar guest lectures by Prof. Neumann and Prof. Kaletja
Exciting topics, interestingly presented: Every first and third Thursday (except during school holidays), RESIST scientists or top-class researchers from external institutions present their topics at ...
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 08/05/2025
Thanks @beatesodeiklab.bsky.social for your kind words. It was a great experience talking about SPR in the “How to…” seminar series organized by the ACHIEVE Academy of the @gesvirologie.bsky.social. I especially enjoyed the discussion part of the event
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Nature @nature.com · 30/03/2025
"This is my home - I really love my country. But a lot of my mentors have been telling me to get out, right now" 75% of US scientists who answered our poll are considering relocating. Read the full story: go.nature.com/3QS4TLC
A graphic entitled "so long, farewell". It reads: "Many of the 1608 respondents who answered the question below in a Nature survey said that the election of Donald Trump as president had affected their future plans."
It then shows the question: "Are you a US researcher who is considering leaving the country following disruptions to science prompted by the Trump administration?"
An orange bar shows 75.3% respondents said yes. A blue bar shows 24.7% respondents said no.
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Nature @nature.com · 30/03/2025
An immigration crackdown in the United States is rattling the global research community, with high-profile detentions and deportations of academics stoking fears even for travellers with valid entry documents. go.nature.com/3FG63rf
go.nature.com
‘Anxiety is palpable’: detention of researchers at US border spurs travel worries
Nature - Several high-profile incidents in the past month have scientists on edge.
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Thiago Carvalho @cyrilpedia.bsky.social · 28/03/2025
'Among those NIH-funded projects are more than 100 clinical trials that now may be forced to halt abruptly, agency officials told me. And those officials expect further orders to cancel hundreds more.'
theatlantic.com
The NIH’s Most Reckless Cuts Yet
Ending clinical trials with no warning can put patients at risk.
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Nature @nature.com · 29/03/2025
🧪 A paralysed man can stand on his own after receiving an injection of neural stem cells to treat his spinal cord injury go.nature.com/4jaZ3RB
go.nature.com
Paralysed man stands again after receiving ‘reprogrammed’ stem cells
Nature - Another man also regained some movement, but two others experienced minimal improvement.
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Nathan Kalman-Lamb @nkalamb.bsky.social · 29/03/2025
Hundreds of international students have just received an email telling them their visas have been revoked. The ‘justification’ is campus activism or social media posts. timesofindia.indiatimes.com/world/us/hun...
The biggest reason government officials aren't giving any specifics about the criteria by which these arrests and deportations are selected, is that the criteria is "pro-Israel think-tanks and advocacy organizations created lists of troublesome individuals and gave them to us."
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WHO @who.int · 29/03/2025
At least 95% measles vaccine coverage is needed in all communities to prevent #measles and stop outbreaks. The only way to prevent measles? Two doses of measles vaccine. Let’s close the gap and keep measles away!
At least 95% vaccine coverage of 2 doses is needed to stop measles outbreaks.
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Doctors Without Borders @doctorswithoutborders.org · 28/03/2025
Terrible news today of a powerful Myanmar earthquake that shook communities across Southeast Asia. Our staff working in Myanmar and Thailand are safe and accounted for. Swift and unhindered access to the affected areas is critical. More here: www.doctorswithoutborders.org/latest/msf-r...
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Matt Novak @paleofuture.bsky.social · 29/03/2025
No food or supplies have been allowed into Gaza in over three weeks
wfp.org
Hunger looms again in Gaza as WFP food stocks begin to run out | World Food Programme
GAZA, Palestine – Hundreds of thousands of people in Gaza are again at risk of severe hunger and malnutrition as humanitarian food stocks in the Strip dwindle and borders remain closed to aid. Meanwhi...
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Constant Screaming @ajaxsinger.bsky.social · 18/03/2025
We are very close to a near cure for two of the highest-mortality cancers we know: glioblastoma and pancreatic cancer. These are both mRNA based treatments which are losing their funding during stage I and II trials. Thousands will die needlessly because of this motherfucker and his lies.
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Nature @nature.com · 22/03/2025
A measles outbreak in the United States is growing, with no end in sight. We asked specialists how bad things could get. go.nature.com/4kOtwXe
go.nature.com
Measles is surging in the US: how bad could it get?
Nature - Researchers flag groups that should get an extra dose of measles vaccine as case numbers continue to rise in Texas and neighbouring states.
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Jenny Fields @jenniefields.bsky.social · 22/03/2025
This broke my heart when I entered the bookstore. I was compelled to take a photo because I can’t believe we’re here. Thank you Barnes & Noble in Wareham, Massachusetts for placing it as first table when you walk in.
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 23/03/2025
It is essential to keep funding the NIH
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Beate Sodeik @beatesodeiklab.bsky.social · 19/03/2025
Discussions on bird flu in the US. 🤨 If it’s not human and animal health for you, if it’s not ethics for you, it’s at least economics. 🤷🏻‍♀️
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Helen Branswell 🇨🇦 @helenbranswell.bsky.social · 19/03/2025
The former head of PEPFAR pleads for the preservation of the lifesaving program. @cohenjon.bsky.social speaks with John Nkengasong. www.science.org/content/arti...
science.org
Outgoing head of heralded U.S. global HIV/AIDS program urges Trump to reverse cuts
John Nkengasong, who had helmed PEPFAR since 2022, says “history will remember we showed humanity”
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Lucas Mendes-Monteiro @lucasmendesm.bsky.social · 18/03/2025
Excited to share an Opinion piece that I wrote with my supervisor, @viejoborbolla.bsky.social, now published in Trends in Immunology! We discuss how viral IFNγ-binding proteins might provide mechanistic insights into uncoupling IFNγ-mediated gene expression. www.sciencedirect.com/science/arti...
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 19/03/2025
It was fun to write this Opinion piece together with @lucasmendesm.bsky.social where we suggest strategies to modify interferon gamma to improve its potential applications in the clinic. Just published at @cp-trendsimmuno.bsky.social !
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 10/03/2025
Great talk by @lucasmendesm.bsky.social at the meeting of the @gesvirologie.bsky.social showing how glycoprotein C expressed by varicella zoster virus modulates the activity of interferon gamma!
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 07/03/2025
With this skin organoid model presented by Manja Czech-Sioli she can monitor cell-specific responses to virus infections in a 3D context. Great work! Looking forward to collaborate with Manja studying VZV infection of skin and neuronal organoids in @deep-dv-for5200.bsky.social
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 07/03/2025
Great talk by @josephineschenk.bsky.social at the @gesvirologie.bsky.social meeting in Hamburg! 👏👏👏
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 04/03/2025
Looking forward to learning about #virology and meeting many friends and colleagues @gesvirologie.bsky.social
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Nature @nature.com · 03/03/2025
Repeated threats to research funding and the mass firings of federal workers have pushed some scientists to take on unfamiliar roles as activists, speaking at rallies, calling legislators and forming new pressure groups. go.nature.com/4bt2EI8
go.nature.com
US science is under threat ― now scientists are fighting back
Researchers are organizing protests and making their voices heard as Trump officials slash funding and lay off federal scientists.
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 04/03/2025
We are on our way to the meeting of the German Society for Virology @gesvirologie.bsky.social. If you’re attending, don’t miss the talks by @lucasmendesm.bsky.social, @josephineschenk.bsky.social and @ninaplueckebaum.bsky.social, as well as Nadine Brückner’s poster
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Eric Topol @erictopol.bsky.social · 01/03/2025
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 28/02/2025
Congratulations George and Katja!
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 28/02/2025
Congratulations to @kreylab.bsky.social for this great work. And thanks for bringing us on board! Always a pleasure to work with you
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Kreylab @kreylab.bsky.social · 26/02/2025
Happy to see this study published, a great collaboration between structural, molecular and clinical virology labs! We describe neutralizing antibodies targeting the Hepatitis E virus capsid protein that distinguish between infectious particles and antibody decoy. www.nature.com/articles/s41...
nature.com
Broadly neutralizing antibodies isolated from HEV convalescents confer protective effects in human liver-chimeric mice - Nature Communications
HEV-specific antiviral treatment is still lacking. Here, the authors functionally and structurally characterize broadly neutralizing antibodies isolated from HEV convalescent individuals and show that...
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 25/02/2025
Really awful news for science and society
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The New York Times @nytimes.com · 24/02/2025
Roberta Flack, the magnetic singer and pianist who was one of the most popular artists of the 1970s, died on Monday at 88. Flack was known for her majestic anthems like “Killing Me Softly” and “The First Time Ever I Saw Your Face.” nyti.ms/4h1KzSh
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Nature @nature.com · 21/02/2025
Update: A block on NIH's new policy to slash billions of dollars of research-overhead costs has been extended by a federal judge. The block was set to expire Monday. go.nature.com/3XgyvWn
go.nature.com
‘Devastating’ cuts to NIH grants by Trump’s team put on hold by US judge
The ruling temporarily halts a policy slashing research overhead costs in 22 states, which filed a lawsuit against the biomedical agency.
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Science Magazine @science.org · 21/02/2025
Already bruised by the Trump administration’s first round of firings of federal workers, employees at NIH faced more bad news. NIH’s 27 institute directors were told this week that the agency must cut staffing back to 2019 levels, or at least 10% below its 2024 tally. scim.ag/3EP8gjy
scim.ag
More NIH job cuts coming? Agency's scientists already reeling after week of firings
NIH is appealing loss of some lab leaders among in-house research program while bracing for the next actions from the Trump administration
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Viejo-Borbolla Lab @viejoborbolla.bsky.social · 20/02/2025
Happy to share our publication in #PlosPathogens investigating repression of varicella zoster virus in neuron-like cells: journals.plos.org/plospathogen... Thanks to @dandepledge.bsky.social and other colleagues for their contribution!
journals.plos.org
Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone deposition
Author summary Varicella zoster virus (VZV) establishes latent infection exclusively in human neurons. This phase of infection is characterized by restricted viral gene expression, lack of detectable ...
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Jeff (Hot Type) Jarvis @jeffjarvis.bsky.social · 08/02/2025
Their aim is nothing short of a new Dark Ages. Anti-science, anti-education, anti-democracy, in favor of needless human suffering. NIH cuts billions of dollars in biomedical funding, effective immediately www.washingtonpost.com/health/2025/...
washingtonpost.com
NIH cuts billions of dollars in biomedical funding, effective immediately
The move halts a large slice of money for most universities and research institutions virtually overnight, imperiling vital research in everything from cancer to heart disease.
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