Reposted by @twotwotwo.bsky.social
“Individuals in the lowest genetic risk decile with high social burden exhibited prevalence comparable to or exceeding that in the highest genetic risk decile with low social burden.”
cell.com
Considering social risk alongside genetic risk for bipolar disorder in the All of Us Research Program
Polygenic risk scores capture only a fraction of bipolar disorder liability. This
multi-ancestry study of 115,275 All of Us participants demonstrates that social risk
factors confer substantial explan...