Mitochondrial tricarboxylic acid (TCA) cycle metabolites have emerged as critical regulators of immunity and inflammation beyond their canonical metab…

A preprint by Lunger et al. reports macrophage engineering through constitutively active synthetic cytokine receptors to induce polarization states that are unobtainable with natural cytokine receptor...

A preprint by Lunger et al. reports macrophage engineering through constitutively active synthetic cytokine receptors to induce polarization states that are unobtainable with natural cytokine receptor...

Nature Immunology - Jena, Qu et al. show that mannadjuvant, a formulation of fungal mannan and aluminum hydroxide, increases the magnitude, durability and breadth of the response elicited by...

Type III interferons are essential immune mediators playing pleiotropic roles during health and disease. In this review, we highlight the molecular and cellular pathways that lead to the production of...

Petrov et al. identify an age-dependent shift in interferon signaling during SARS-CoV-2 infection, with older individuals favoring a STAT3-driven inflammatory response. This mechanistic insight helps ...

Vollzeit | 16.04.2025 | BIH Berlin Mitte