Subgroup analyses can inform whether intervention effects differ systematically across participants, but they are prone to false-positive findings, low power, and selective reporting. Stepped-wedge cl...

In this pragmatic trial, rTKR as delivered in routine practice was more costly than cTKR and did not provide a clinically meaningful patient benefit at 12 months after randomisation. The two groups ha...

Central data monitoring involves activities performed by trial staff to improve the quality, integrity, and reliability of trial processes and data co…

People receive rehab only three to four days a week in hospital – and one to two days once they are discharged, data suggests The NHS is failing stroke patients and limiting their chances of recovery because of a shortage of rehabilitation care staff, health leaders have said. More people are surviving strokes than ever before in the UK. But their hopes of getting better are being dashed because of a lack of physiotherapists and other specialist staff, according to the Chartered Society of Physiotherapy and the Association of Chartered Physiotherapists in Neurology. Continue reading...

Results from a review of a new osteoarthritis pathway for hip and knee patients shows faster access to care, improved patient outcomes and major cost savings across two pilot sites.

Objectives To identify and prioritise research uncertainties regarding the assessment, management and rehabilitation of patients with problematic hip replacements through a national Priority Setting P...

We know that there’s a huge amount to do, so we need to prioritise.  We will be focusing on some key themes for support for our current plan period (which you can find in our Strategic Framework 2025-...

Disruption and uncertainty in the US are leading many clinical trials to consider other countries for participation. Jennifer Lutz , Neha Bhatt , and Flynn Murphy report on the changing landscape—and ...

Background Anterior glenohumeral instability is a common issue, particularly among young and active individuals. Arthroscopic Bankart repair is an effective surgical method for achieving long-term sho...

BMC Musculoskeletal Disorders - This systematic review and meta-analysis aimed to compare postoperative gait and functional outcomes between the Hardinge approach (HA) and the posterolateral...

This narrative review presents five observations concerning 0 to 10 pain Visual Analog Scale (VAS)/Visual Numeric Scale (VNS) scores in routine care patients with primary diagnoses of rheumatoid arth...

BMC Musculoskeletal Disorders - We aimed to conduct a qualitative prospective preference assessment (PPA) to assess participants’ willingness to enroll in a planned randomized controlled...

Oxford Trauma and Emergency Care at Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), along with the Critical Care Research Team at Nuffield Department of Clinic...

Introduction The Latarjet procedure is the mainstay treatment in high-demand patients with substantial glenoid bone loss or after failed capsulolabral repairs. Patients typically return to sport (RTS)...

The ‘ISSHOOs (Identifying Social factors that Stratify Health Opportunities and Outcomes) in pain research’ project endeavoured to address the paucity and inconsistency of equity-relevant, socio-demog...

Numerous studies have assessed the adherence of published systematic reviews to the PRISMA 2020 statement. We aimed to summarise the characteristics and methods of development of the tools used to ass...

Background Patient-reported outcome measures (PROMs) are increasingly used to assess treatment effectiveness in various domains from the patients’ perspective. This systematic review aimed to identify...

Background Total ankle replacement (TAR) has evolved considerably over the past five decades as an alternative to arthrodesis for the management of end-stage ankle osteoarthritis. While early TAR desi...

Knee cartilage defects are common and often encountered during arthroscopy, with an incidence of 60–66%. The aim of this study was to determine current strategies in the surgical and non-surgical mana...