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Tom Samuels

@thomashasamuels.bsky.social
2.1K followers 325 following 21 posts

NIHR Academic Clinical Fellow in Infectious Diseases @ UCL and soon to be NIHR Doctoral Fellow @ UCL. Infection diagnostics, data science and predictive modelling.

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Tom Samuels @thomashasamuels.bsky.social · 30/04/2025
A novel personalised mortality risk prediction tool for HIV-associated cryptococcal meningitis could lead to future treatment stratification trials - less intensive regimens for less unwell patients? Our new manuscript. www.thelancet.com/journals/lan... #IDsky #HIV #GlobalHealth #meningitis #fungal
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Tom Samuels @thomashasamuels.bsky.social · 30/04/2025
Very excited to share our new piece of work in the Lancet Global Health @lancetgh.bsky.social – Periskope-CM, a set of personalised risk prediction tools for HIV-associated cryptococcal meningitis mortality: www.thelancet.com/journals/lan... #IDsky #HIV #GlobalHealth #meningitis #fungal 1/8
thelancet.com
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Tom Samuels @thomashasamuels.bsky.social · 16/02/2025
Fantastic piece of work by @richarddriley.bsky.social and others - this is the next step we need to be taking when we report the performance of clinical prediction models.
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Onisillos @onisillos.bsky.social · 17/01/2025
New research article in The Lancet Microbe Assessment of MpoxPlex, a high-throughput and multiplexed immunoassay: a diagnostic accuracy study www.thelancet.com/journals/lan... #IDSky #ClinMicro #ViroSky #Mpox #OpenAccess #OA
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 15/01/2025
🆕💫 Analysis of AMBITION RCT Individuals started ART w/in 2 wks before presenting with cryptococcal meningitis, presumably active cryptococcal infection, have higher mortality, whereas those presenting on ART for > =2 wks have a more favorable prognosis #idsky academic.oup.com/cid/advance-...
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Gabriele Pollara @gpollara.bsky.social · 15/01/2025
Interesting to #IDSky & #ClinMicro
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Hilda Bastian @hildabast.bsky.social · 28/12/2024
Ever wonder about the basis for fear-mongering & conspiracy theories about mRNA vax? Wish you had a place to go when someone cites "proof"? I've got you covered! In my latest @plos.org I buckle up for the waves of anti-vax muck likely to come in 2025. 1/2 absolutelymaybe.plos.org/2024/12/28/g...
absolutelymaybe.plos.org
Getting Ready for More mRNA Vaccine Fear-Mongering: A Compendium - Absolutely Maybe
Recently, I wrote about a depressingly successful campaign against the introduction of a next generation Covid vaccine in Japan. It is a…
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Tom Samuels @thomashasamuels.bsky.social · 28/12/2024
Great piece in the Lancet Microbe from colleagues at HTD and RIPL about the vaccinating for dengue in travellers! 👏🏻 www.thelancet.com/journals/lan... Full details of how to go about it all for Uk travellers in the excellent Green Book travelhealthpro.org.uk/media_lib/ml... #IDSky #ViroSky
thelancet.com
New dengue vaccine for UK travellers: recommended only for those with a previous infection
Dengue virus is the most abundant and rapidly spreading arbovirus worldwide. 390 million dengue infections are estimated to occur annually, of which approximately 25% are symptomatic.1 Climate change and urbanisation have contributed to the spread of the vectors (Aedes mosquitoes) and enabled sustained transmission in regions that were previously not affected.2 Although the burden of the disease is largely confined to Asia and central or south America, autochthonous spread has been increasing in central and southern Europe.
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Gabriele Pollara @gpollara.bsky.social · 18/12/2024
Potential delivery of some antibiotics too? Clearly there may be some significant issues with volume of fluid to be delivered subcutaneously! #OPAT #IDSky #clinmicro #AMR
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Michael Bazaco @mcbazacophd.bsky.social · 18/12/2024
Fatal Case of Crimean-Congo Hemorrhagic Fever, Portugal, 2024 #IDSky #EpiSky
wwwnc.cdc.gov
Fatal Case of Crimean-Congo Hemorrhagic Fever, Portugal, 2024
Fatal Crimean-Congo Hemorrhagic Fever, Portugal
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Tom Samuels @thomashasamuels.bsky.social · 06/12/2024
Our letter about HLH in murine typhus has just been published in the Journal of Infection! doi.org/10.1016/j.ji.... Many thanks to my co-authors, with a special mention to Sophie Skarbek, Sana Sharrack, and @jamesmeiring.bsky.social for all your efforts 🙏
doi.org
Redirecting
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Mahdad Noursadeghi @mnoursad.bsky.social · 01/12/2024
Hi @mattfrieman.bsky.social - TL;DR - our key conceptual advance is that different blood transcriptional biomarkers discriminate early and late phases of infection as a result of cell-specific epigenetic regulation and have important translational applications for respiratory virus infections:
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James Greenan-Barrett @jgreenanbarrett.bsky.social · 01/12/2024
Check out our paper on RNA biomarkers in COVID-19 MX1 expression occurred early in infection before PCR detection…potential role to stratify treatment #IDSky
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BK. Titanji @boghuma.bsky.social · 21/11/2024
Poignant frontline perspective of a #Rwandan physician responding to the recent #marburg outbreak. It is well worth a read. We are are two weeks into the 42 day countdown to declaring the outbreak over🤞🏾. These brave HCPs kept us safe. #medsky #idsky 🧪 www.nejm.org/doi/full/10....
nejm.org
Fight or Flight — Facing the Marburg Outbreak in Rwanda | NEJM
Having diagnosed two ICU patients with the first known cases of Marburg virus disease in Rwanda, a physician must prioritize limiting spread, despite pleas for transfer from the patients’ families.
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Tom Samuels @thomashasamuels.bsky.social · 21/11/2024
Fantastic session at #Medplus in the @rcphysicians.bsky.social today chairing cases from the Imported Fever Service with Sarah Logan. Thanks a bunch to all our panelists and speakers, you were all brilliant. If you’re at Med+ or joining online and missed it, do watch it back!
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