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The Menachery Lab

@themenacherylab.bsky.social
1.7K followers 303 following 144 posts

A coronavirus lab looking for low hanging pebbles and shiny fruit. Emory University

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The Menachery Lab @themenacherylab.bsky.social · 3h
Post grant submission me is pretty annoyed with pre grant submission me. Going to be late on. .. everything.
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🌬Breeze @cool-summer-breeze.bsky.social · 24/09/2026
This is the Stolen Neighbors Quilt. Each of the 11,000 squares represents a person taken by ICE in Minnesota.
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The Menachery Lab @themenacherylab.bsky.social · 16/09/2026
A new/old SARS-CoV-2 paper for us is now at in @natcomms.nature.com www.nature.com/articles/s41... We submitted first in 2023 and due to a variety of reasons, it is now out, in 2026. The manuscript details our look into conserved SARS-CoV-2 Omicron mutations outside the receptor binding domain.
nature.com
Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection - Nature Communications
Spike mutations in SARS-CoV-2 Omicron variants impact vaccine-mediated protection. In this study, the authors identify mutations that also alter spike cleavage and virus entry and that these Omicron m...
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The Menachery Lab @themenacherylab.bsky.social · 09/09/2026
Our new paper on #SARSCoV2 antagonism of stress granule (SG) responses is now out in JVI: journals.asm.org/doi/10.1128/... The work shows that disrupting motifs in NSP3 & Nucleocapsid activates SGs, attenuates viral replication, reduces disease, & offers a new approach to attenuate CoVs (1/4).
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Tulilab.com @tulilab.bsky.social · 20/08/2026
Reposting again! Deadline is coming up!
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American Society for Virology @amersocvirology.bsky.social · 27/07/2026
Vineet Menachery shuffles the viral deck, diving into recombination and host selection as drivers of viral evolution. Also, do coronaviruses wear visors? #asv2026
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Connor G G Bamford @connorggbamford.bsky.social · 07/07/2026
Please share 🚨 We have a postdoc position open on avian influenza virus tracking and genomics across natural to develop an early-warning system to protect human and animal health hrwebapp.qub.ac.uk/tlive_webrec...
hrwebapp.qub.ac.uk
Job profile
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The Menachery Lab @themenacherylab.bsky.social · 19/06/2026
New paper from our lab on #SARSCoV2 antagonism of stress granule (SG) responses: www.biorxiv.org/content/10.6... Work shows that disrupting 2 key viral motifs that antagonize SGs attenuates viral replication, disease, & may offer a new approach to attenuate CoV infection. A short thread (1/6).
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c t @whatulysses.bsky.social · 18/06/2026
can't argue with this.
screenshot from a pop-up window received after downloading Microsoft Office. It features a yellow triangle with an exclamation point and the text, "'Microsoft Teams' is damaged and can't be opened. You should move it to the Trash."
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American Society for Virology @amersocvirology.bsky.social · 09/06/2026
ASV is alarmed by the US HHS to suspend and debar Dr. Ralph Baric from federal funding. Read our open letter below:
Open letter from ASV to protest US HHS actions against Dr. Ralph Baric.
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Lisa Gralinski @lisagralinski.bsky.social · 13/05/2026
Bullshit is nicer than anything I have to say about this constant harassment. www.science.org/content/arti...
science.org
Virologist accused of starting COVID-19 will fight U.S. ban on funding
HHS memo says Ralph Baric had a “pattern of deception” in describing virus studies long before pandemic
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The Menachery Lab @themenacherylab.bsky.social · 11/05/2026
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Markus Eichhorn @markuseichhorn.bsky.social · 07/05/2026
Bingo! Do I win a prize now?
Comic strip titles self-sabotaging academic habits that feel normal, featuring nine panels.
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Tim Sheahan @timothysheahan.bsky.social · 07/05/2026
SARS-CoV-2 without proofreading are sad and weak viruses. out now in #mBio #lovevirology journals.asm.org/doi/10.1128/...
journals.asm.org
Loss of nsp14-exonuclease activity impairs the replication, proofreading, fitness, and pathogenesis of SARS-CoV-2 | mBio
Coronaviruses (CoV) are important human pathogens causing hundreds of millions of infections and millions of deaths over the past 20 years. The study of how these viruses multiply and cause disease id...
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The Menachery Lab @themenacherylab.bsky.social · 28/04/2026
Much of the highest risks (severe disease, death) of COVID-19 is over for most. Do people still need to vaccinate for COVID each year? The article below interviews a number of scientists and researchers including myself. We all acknowledge the risk has diminished, but much still remains unknown.
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The Menachery Lab @themenacherylab.bsky.social · 23/03/2026
Congrats to Angel & Elias as they defended their theses (not thesi apparently) last week at UTMB. They did a great job & we look forward to pubs from both (hint, hint) as they wrap up. Both published their work recently on SARS2: FCS tinyurl.com/2pw3dr4m & Stress Granules tinyurl.com/ujxfcu5d
Picture of Angel after defensePictures with PIs and Angel after defensePicture of Elias after defensePicture of Elias with Pis after defense
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The Menachery Lab @themenacherylab.bsky.social · 13/02/2026
Great regional conference for virologist in the southeast. Abstract due next week.
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The Menachery Lab @themenacherylab.bsky.social · 02/02/2026
"This is pitiful. A thousand people freezing their butts off waiting to worship a rat. What a hype. Groundhog Day used to mean something in this town. They used to pull the hog out, and they used to eat it. You're hypocrites, all of you!"
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Tim Sheahan @timothysheahan.bsky.social · 14/01/2026
Our new preprint on #SARSCoV2 nsp14 #exonuclease function in replication fidelity and fitness. ExoN- viruses are attenuated in vitro and in vivo but w/o #interferon signaling replication is largely restored! Suggests nsp14 plays a role in innate antagonism in vivo www.biorxiv.org/content/10.6...
biorxiv.org
Loss of nsp14-exonuclease activity impairs the replication, proofreading, fitness and pathogenesis of SARS-CoV-2
Coronaviruses (CoVs) replicate their RNA genomes with increased fidelity than other RNA viruses, a mechanism mediated by the proofreading and recombination activities of the exoribonuclease domain of ...
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The Menachery Lab @themenacherylab.bsky.social · 14/01/2026
Our paper on the role of #SARSCoV2 NSP3 in stress granule control is now out in JVI. Reposting our original BioRXIV thread on the summary. journals.asm.org/doi/10.1128/...
journals.asm.org
Key residues in SARS-CoV-2 NSP3 hypervariable region are necessary to modulate early stress granule activity | Journal of Virology
Stress granules play a key role in host-antiviral defenses, and viruses have developed strategies to antagonize their activity. For SARS-CoV-2, the virus has two proteins that antagonize stress granul...
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I-75 Scientist @flscitriguy.bsky.social · 29/12/2025
Excellent news. The NIGMS Building Undergraduate Research Training (BURT) T34 NOFO is published. First due is Feb 25th, for December 26 funding. This condenses previous UG NOFOs so reach out to email/previous PO if you have Qs. files.simpler.grants.gov/opportunitie...
files.simpler.grants.gov
PAR-26-033: NIGMS Institutional Biomedical Undergraduate Research Training (BURT) Program (T34)
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Yiyang (Tommy) Zhou @tommygottago.bsky.social · 19/12/2025
The very first @nanoporetech.com MinION library of @themenacherylab.bsky.social at Emory! So far so good! I've been missing Nanopore for a while! Merry Christmas!
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Mehle Lab @mehlelab.bsky.social · 19/12/2025
🧵 Thread on our new @natcomms.nature.com paper: TLDR -- ADP-ribosylation inhibits viral replication and represents a previously under-appreciated arm of innate immunity during flu infection. Read along for the details…. (1/11) www.nature.com/articles/s41...
nature.com
Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection - Nature Communications
Influenza A virus infection causes a dramatic upregulation of ADP-ribosylation that as part of the cellular antiviral response, a process that is counteracted by the viral NS1 protein.
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Chris Morran @themorrancave.bsky.social · 19/12/2025
When Hannah’s pharmacy began filling her tacrolimus prescription with a generic version, the lung transplant patient didn't know something very important: Months earlier, an FDA-commissioned study concluded that this generic was not equivalent to the brand drug -- and that her life was at risk.
propublica.org
Fighting for Breath: The FDA’s Lax Generic Drug Rules Put Her Life at Risk
Lung transplant patient Hannah Goetz’s life depended on the generic version of the critical drug tacrolimus. It was supposed to be equivalent to the brand-name medication — but the FDA doesn’t always ...
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Ryan Langlois @langloislab.bsky.social · 15/12/2025
Put a perspective piece together on how fever may have driven the evolution of antiviral genes: rupress.org/jem/article/...
rupress.org
Does fever drive the evolution of antiviral genes? | Journal of Experimental Medicine | Rockefeller University Press
Fever is an evolutionary conserved response to pathogens. In this Perspective, Langlois hypothesizes that antiviral genes are selected for their function a
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Prof Peter Hotez MD PhD DSc(hon) @peterhotezmdphd.bsky.social · 13/12/2025
Frankenstein
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Chris Brooke @christopherbrooke.bsky.social · 12/12/2025
Check out @lizthayer.bsky.social's new preprint exploring factors that influence cell-to-cell heterogeneity in interferon (IFN) induction potential!
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Priya Shah @whatthefugacity.bsky.social · 12/12/2025
Are you an early career researcher applying to faculty positions this cycle? My #1 piece of advice is to keep an open mind about what the right department looks like. You might be surprised. journals.asm.org/doi/10.1128/...
journals.asm.org
On professional mutualism: a blueprint for early-career virologists | Journal of Virology
As virologists, we are constantly studying symbiosis. Viruses are obligate intracellular parasites and symbionts as a result. Symbiotic virus-host relationships can be antagonist, neutral, or mutualistic for the host (1). It is these mutualistic relationships that are perhaps the most curious. How can a virus, which uses cellular resources, benefit a host? It all depends on context and the right conditions for mutualism to emerge. However, we should not stop at understanding virus-host mutualism from a scientific perspective. We should also consider mutualistic symbiotic relationships in our careers. The right conditions for professional mutualism in virology may surprise you.
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The Menachery Lab @themenacherylab.bsky.social · 10/12/2025
New paper from our lab on CoV recombination in @natcomms.nature.com: www.nature.com/articles/s41... Collaboration w/ @andrewrouth.bsky.social, the work led by @tommygottago.bsky.social & Yani provides insights into #SARS2 recombination & immune induction. Some takeaways for the TLDR crowd (1/13)
nature.com
SARS-CoV-2 EndoU-ribonuclease regulates RNA recombination and impacts viral fitness - Nature Communications
Known to augment host innate immunity, Zhou and Ahearn et al. shows that a SARS-CoV2 NSP15 mutant also increases viral recombination and reduces sub-genomic message. Results articulate a novel role fo...
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The Menachery Lab @themenacherylab.bsky.social · 25/11/2025
A new preprint from our group on control of stress granules (SGs) by #SARSCoV2. Working with Jakob Nilsson's group, we identified key residues in SARS2 NSP3 critical for binding FMRP proteins & disrupting SGs formation. www.biorxiv.org/content/10.1...
biorxiv.org
Key residues in SARS-CoV-2 NSP3 hyper variable region are necessary to modulate early stress granule activity.
Antagonism of the host responses that limits viral replication is critical to the success of infection. Recently, we identified that the hypervariable region (HVR) of SARS-CoV-2 NSP3 binds to FXR1 and...
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The Menachery Lab @themenacherylab.bsky.social · 13/11/2025
A nice honor to be named to Clarivate’s Highly Cited Researchers for 2025. The recognition is a testament to all the hard work my research group and our collaborators have done over the years. news.emory.edu/stories/2025...
news.emory.edu
Nine Emory faculty recognized among world’s most influential researchers in 2025 | Emory University | Atlanta GA
Nine Emory faculty members are among the list of the world's most influential and highly cited researchers for 2025, as compiled by the data analytics firm Clarivate.
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Tim Sheahan @timothysheahan.bsky.social · 06/11/2025
New #coronavirus #postacute lung pathogenesis paper from my friend Dr. John Powers is up at @asm.org JVI. journals.asm.org/doi/10.1128/... Confusing as to why this link shows a rotund blue bird. #PASC #SARSCoV2 #Omicron #LoveVirology #JVI #ASM #virology
journals.asm.org
Mouse-adapted SARS-CoV-2 Omicron BA.5 infection induces post-acute lung fibrosis in BALB/c mice | Journal of Virology
To best combat the evolving landscape of SARS-CoV-2 variants of interest and variants of concern, the development of effective small animal models is of critical importance. Herein, we describe the de...
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The Lustgarten Foundation @lustgarten.org · 01/10/2025
NIH will spend its full $48B budget — but multi-year funding means fewer projects, record-low grant success, and a warning for U.S. science.👉 lfdn.org/3KOs2hT 💜Learn how you can support NIH funding: www.lustgarten.org/forging-ahead #ResearchMatters
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The Menachery Lab @themenacherylab.bsky.social · 12/09/2025
Feels like everything has moved slow since restarting here at Emory last year, but glad to have been nominated by my new peers and selected for this recognition. med.emory.edu/about/facult...
Recognition of being selected for Emory School of Medicine Research Appreciation Day 2025
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The Menachery Lab @themenacherylab.bsky.social · 09/09/2025
I wish my all my students labeled their figures as well as my daughter.
Hand drawn picture with a legend
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jamelle @jamellebouie.net · 29/08/2025
there is no question in my mind that rfk jr is the most dangerous person in this administration and that his eugenicist ideology threatens the lives of millions of people www.advocate.com/politics/dem...
advocate.com
RFK Jr.’s damage to the CDC is ‘past the point of no return,’ Dr. Demetre Daskalakis warns
“The CDC you knew is over,” the infectious diseases doctor told The Advocate. “Unless someone takes radical action, there is nothing there that can be salvaged.”
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Marc Veldhoen @marcveld.bsky.social · 28/08/2025
What the CDC lost: a closer look at the top-ranking officials who have quit HHS Secretary RFK Jr. says agency suffers from ‘malaise,’ but departed officials had deep expertise Knowledge, experience and talent lost due to political ideology.
statnews.com
What the CDC lost: a closer look at the top-ranking officials who have quit
Here is a closer look at the top-ranking officials who resigned from the CDC this week.
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Demetre Daskalakis @drdemetre.bsky.social · 28/08/2025
Enough is enough. The health of the country is in danger. Read our resignation letters: insidemedicine.substack.com/p/breaking-n...
insidemedicine.substack.com
Breaking News: Read three top CDC officials' resignation emails.
The end of an era.
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Eric Columbus @ericcolumbus.bsky.social · 28/08/2025
Wow
The recent shooting at CDC is not why I am resigning. My grandfather, who l am named after, stood up to fascist forces in Greece and lost his life doing so. I am resigning to make him and his legacy proud. I am resigning because of the cowardice of a leader that cannot admit that HIS and his minions' words over decades created an environment where violence like this can occur. I reject his and his colleagues' thoughts and prayers, and advise they direct those to people that they have not actively harmed.
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Journal of Experimental Medicine @jem.org · 15/08/2025
#WomenInSTEM becoming independent: People should feel free to be themselves and do great science. We asked ten women researchers about their science and the process of setting up a lab as an independent researcher: rupress.org/jem/article/...
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The Menachery Lab @themenacherylab.bsky.social · 12/08/2025
www.wabe.org/man-fired-18...
wabe.org
Man fired 180 shots, breaking 150 windows, in CDC attack
The man who attacked the CDC headquarters in Atlanta on Friday fired more than 180 shots into the campus and broke about 150 windows, with bullets piercing “blast-resistant” windows and […]
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The Menachery Lab @themenacherylab.bsky.social · 11/08/2025
Spent the weekend here reflecting & reconnecting. A sorrowful few days thinking of what was lost. The CDC is ubiquitous to our community. An attack on us all. Officer David Rose died protecting us. Take a moment to support & share efforts for the family he left. www.gofundme.com/f/7xahr9-off...
gofundme.com
Donate to Officer Rose's Official GoFundMe, organized by Mrs Rose
Officer David Rose was more than a dedicated public servant - He was a loving father, a dev… Mrs Rose needs your support for Officer Rose's Official GoFundMe
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The Menachery Lab @themenacherylab.bsky.social · 08/08/2025
Lab members in ATL are all accounted and safe.
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The Menachery Lab @themenacherylab.bsky.social · 16/07/2025
#ASV2025 is where you run into a Nobel Laureate at the bar late at night and they wish you a happy birthday. My birthday is in March. But thanks. Happy birthday @lakdawalalab.bsky.social
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The Menachery Lab @themenacherylab.bsky.social · 14/07/2025
Recycling an old twitter thread for #ASV2025: Heading to #ASV2023. One of my favorite meetings in virology. My new students asked me for some tips on how to approach the meeting, so I thought I’d share some thoughts on scientific networking
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Dr. Kat Napaaqtuk❄️ @napaaqtuk.bsky.social · 20/06/2025
A short thread about the people in my lab who will present posters and give rapid talks at #ASMmicrobe: 🧵
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pucksandviruses.bsky.social @pucksandviruses.bsky.social · 20/06/2025
Excited for the recipient of the @ASM Elizabeth O. King Lecturer Award at this year’s #ASMMicrobe.
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