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Andrew Routh

@andrewrouth.bsky.social
1.3K followers 651 following 1 posts

Molecular virologist | Deep-sequencer | Institute Investigator at Scripps Research | Co-founder and CSO at ClickSeq Technologies | 🇬🇧 in 🇺🇸 | He/him | Dad

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Reposted by Andrew Routh
The Menachery Lab @themenacherylab.bsky.social · 10/12/2025
New paper from our lab on CoV recombination in @natcomms.nature.com: www.nature.com/articles/s41... Collaboration w/ @andrewrouth.bsky.social, the work led by @tommygottago.bsky.social & Yani provides insights into #SARS2 recombination & immune induction. Some takeaways for the TLDR crowd (1/13)
nature.com
SARS-CoV-2 EndoU-ribonuclease regulates RNA recombination and impacts viral fitness - Nature Communications
Known to augment host innate immunity, Zhou and Ahearn et al. shows that a SARS-CoV2 NSP15 mutant also increases viral recombination and reduces sub-genomic message. Results articulate a novel role fo...
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Reposted by Andrew Routh
Kristian G. Andersen @kgandersen.bsky.social · 10/04/2025
I could literally quote every single sentence of this commentary, so I'm not going to - just read the whole thing. And thanks, Dr. Bieniasz, for saying it as it is and showing true leadership. We need that from more scientists and scientific leaders. www.theguardian.com/commentisfre...
theguardian.com
We are witnessing the destruction of science in America | Paul Darren Bieniasz
If we stay on this administration’s course, future life-saving medicines may never be invented
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Reposted by Andrew Routh
Scripps Research @scripps.edu · 10/04/2025
If someone—or something—is infected with both #birdflu (H5N1) and seasonal flu (H1N1), the viruses can swap genes through reassortment. Scientists are watching closely, as this genetic shuffle could create a new strain with unpredictable traits—like easier human transmission. More: ow.ly/aoeA50VxSwG
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Reposted by Andrew Routh
Asher Leeks @asherleeks.bsky.social · 28/03/2025
Can we use social evolution to fight pathogens? @asgriffin.bsky.social and I review the evidence for 'cheat therapy' in bacteria and viruses... 🧪🦠 #socialviruses #evosky #virosky 1/3
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Reposted by Andrew Routh
Kay Choi Lab @kaychoi-lab.bsky.social · 13/03/2025
How does enterovirus protease specifically recognize its viral RNA genome? Hint: It takes two! Our first post on bluesky - Happy to share our new publication. Structure of coxsackievirus cloverleaf RNA and 3C protease dimer establishes its RNA-binding mechanism www.science.org/doi/10.1126/...
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