Axonal transcriptomes have been characterized, but their regulation and role in neuronal circuits remain unclear. Here authors uncover activity-dependent RNA localization in axons important for memory...

Cortical areas differ in their patterns of connectivity, cellular composition, and functional architecture. Spike trains, on the other hand, are commonly assumed to follow similarly irregular dynamics...

Using high-density electrophysiological recordings, how internally generated cell assemblies are updated by action plans to meet external goals is explored.

Could the brain’s computational abilities extend beyond neural networks to molecular mechanisms? Akhlaghpour describes how natural universal computation may have evolved via RNA mechanisms.

Three recent papers examine the robustness of reasoning and problem-solving in large language models