Reposted by Hessam AkhlaghpourSam Gershman @gershbrain.bsky.social · 04/04/2025Bridging computation and representation in associative learning: gershmanlab.com/pubs/Gershma...gershmanlab.com 04512
Hessam Akhlaghpour @thehessam.bsky.social · 02/04/2025Just out by Ellen Lau: How single-neuron computation matters for cognitive neuroscience doi.org/10.21428/8e6...doi.orgHow single-neuron computation matters for cognitive neuroscience 081
Reposted by Hessam AkhlaghpourArula Ratnakar @arula-ratnakar.bsky.social · 28/03/2025Future Tense Fiction Magazine asked me to write a short scifi story for them, which would be paired with a response from a scientist. Inspired by work from Cristopher Moore, @thehessam.bsky.social & @lenoreblum.bsky.social I wrote "Coda" And Cristopher Moore wrote the response essay! Links below: 2218
Reposted by Hessam AkhlaghpourEvelina Tutucci @anilevetu.bsky.social · 16/03/2025From the Besse's lab. #RNAbiology #RNAlocalization #spatialbiology www.nature.com/articles/s41...nature.comAxonal RNA localization is essential for long-term memory - Nature CommunicationsAxonal transcriptomes have been characterized, but their regulation and role in neuronal circuits remain unclear. Here authors uncover activity-dependent RNA localization in axons important for memory... 04514
Reposted by Hessam AkhlaghpourJason Shepherd @jasonsynaptic.bsky.social · 17/02/2025Feels weird to promote science right now but here’s a new review/opinion piece from the lab where we outline new insights about how Arc mediates long lasting synaptic plasticity and memory formation. 🧪🧠 kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...kwnsfk27.r.eu-west-1.awstrack.me 912616
Reposted by Hessam AkhlaghpourIpshita Zutshi @ipshitaz.bsky.social · 09/01/2025It’s an incredible feeling to see something you’ve poured your heart into come to life. This work was born from my curiosity about hippocampal “cognitive tuning.” Our interpretation of the environment depends on our actions, constantly evolving as we pursue our goals www.nature.com/articles/s41...nature.comHippocampal neuronal activity is aligned with action plans - NatureUsing high-density electrophysiological recordings, how internally generated cell assemblies are updated by action plans to meet external goals is explored. 518347
Reposted by Hessam AkhlaghpourPhilipp Brand @pbrand.bsky.social · 08/01/2025I'm thrilled to be opening my own lab this Fall at the @maxplanck.de MPI for Brain Research in Frankfurt. The lab is going to investigate the neuronal and genetic underpinnings of behavioral evolution. We are hiring on all levels. Don't hesitate to share widely and reach out if interested. 2114150
Reposted by Hessam AkhlaghpourWallace Marshall @wallaceucsf.bsky.social · 02/12/2024Where does pattern come from inside cells? in this revised preprint, @aralbright.bsky.social Shows that regionalization of mRNA in a Stentor cell depends on dynein motors and the microtubule cytoskeleton doi.org/10.1101/2023... 315242
Reposted by Hessam AkhlaghpourDavid Colaço @davidcolaco.bsky.social · 02/12/2024@jonathannajenson.bsky.social and I will discuss @thehessam.bsky.social's work in the next session of our International Memory Reading Group 183
Reposted by Hessam AkhlaghpourGualtiero Piccinini @gualtiero.bsky.social · 02/12/2024@thehessam.bsky.social speculates that universal computation implemented by RNA is behind memory and cognition. It's a cool idea, though probably wrong. 1/ 1112
Reposted by Hessam AkhlaghpourNicole Rust @nicolecrust.bsky.social · 02/12/2024I admire trainees stepping up like this to talk about the big questions. @thehessam.bsky.social does a terrific job here talking about the nature of memory storage (synaptic vs not). 4266
Hessam Akhlaghpour @thehessam.bsky.social · 27/11/2024I almost forgot how in the old twitter days, we could have productive exchanges in the comments. It’s happening again for me on bluesky - where I walk away from a discussion with learning something new to look up! 060
Reposted by Hessam AkhlaghpourPessoaBrain @pessoabrain.bsky.social · 27/11/2024𝗪𝗵𝗮𝘁 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻 𝗶𝗺𝗽𝗹𝗲𝗺𝗲𝗻𝘁𝘀 𝘂𝗻𝗶𝘃𝗲𝗿𝘀𝗮𝗹 𝗰𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻? Maybe not neurons, perhaps RNA?? Great episode of Brain Inspired with Hessam Akhlaghpour. Do dynamical systems and/or RNNs implement universal computation? This discussion alone would be worth having. #neuroscience braininspired.co/podcast/199/braininspired.coBI 199 Hessam Akhlaghpour: Natural Universal Computation | Brain Inspired 5358
Hessam Akhlaghpour @thehessam.bsky.social · 26/11/2024Since my early postdoc years, whenever my hands were busy with experiments but my mind was free, I’d listen to Brain Inspired. I would have been thrilled to know that I’d be on Paul’s show in the future, discussing what I think is the most exciting problem in biology. braininspired.co/podcast/199/braininspired.coBI 199 Hessam Akhlaghpour: Natural Universal Computation | Brain Inspired 0174
Reposted by Hessam AkhlaghpourThe Transmitter @thetransmitter.bsky.social · 26/11/2024Could the brain’s computational abilities extend beyond neural networks to molecular mechanisms? Listen to Paul Middlebrooks's latest "Brain Inspired" podcast, in which he talks with @thehessam.bsky.social about how universal computation may have evolved via RNA mechanisms: bit.ly/4eQ4Idcthetransmitter.orgHessameddin Akhlaghpour outlines how RNA may implement universal computationCould the brain’s computational abilities extend beyond neural networks to molecular mechanisms? Akhlaghpour describes how natural universal computation may have evolved via RNA mechanisms. 0359
Reposted by Hessam AkhlaghpourMelanie Mitchell @melaniemitchell.bsky.social · 21/10/2024New post on my Substack: aiguide.substack.com/p/the-llm-re...aiguide.substack.comThe LLM Reasoning Debate Heats UpThree recent papers examine the robustness of reasoning and problem-solving in large language models 3323
Hessam Akhlaghpour @thehessam.bsky.social · 13/10/2024Are transformers/LLMs actually Turing-complete? (i.e., capable of computing anything a standard programming language can compute) I look at 16 papers on the subject. My conclusion is that, despite the claims, no one has proved this yet. lifeiscomputation.com/transformers... 4315
Hessam Akhlaghpour @thehessam.bsky.social · 02/07/2024I need someone to make a comic where people decide the best way to solve a problem is to create an AI far smarter than them and have that solve it. Then that AI, being very smart, decides to create another smarter AI. This goes on recursively, forever, and nothing gets solved. 130