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Hessam Akhlaghpour

@thehessam.bsky.social
345 followers 170 following 45 posts

Check out my blog: lifeiscomputation.com and my personal website: www.akhlaghpour.info

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Reposted by Hessam Akhlaghpour
Sam Gershman @gershbrain.bsky.social · 04/04/2025
Bridging computation and representation in associative learning: gershmanlab.com/pubs/Gershma...
gershmanlab.com
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Hessam Akhlaghpour @thehessam.bsky.social · 02/04/2025
Just out by Ellen Lau: How single-neuron computation matters for cognitive neuroscience doi.org/10.21428/8e6...
doi.org
How single-neuron computation matters for cognitive neuroscience
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Reposted by Hessam Akhlaghpour
Arula Ratnakar @arula-ratnakar.bsky.social · 28/03/2025
Future Tense Fiction Magazine asked me to write a short scifi story for them, which would be paired with a response from a scientist. Inspired by work from Cristopher Moore, @thehessam.bsky.social & @lenoreblum.bsky.social I wrote "Coda" And Cristopher Moore wrote the response essay! Links below:
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Reposted by Hessam Akhlaghpour
Evelina Tutucci @anilevetu.bsky.social · 16/03/2025
From the Besse's lab. #RNAbiology #RNAlocalization #spatialbiology www.nature.com/articles/s41...
nature.com
Axonal RNA localization is essential for long-term memory - Nature Communications
Axonal transcriptomes have been characterized, but their regulation and role in neuronal circuits remain unclear. Here authors uncover activity-dependent RNA localization in axons important for memory...
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Reposted by Hessam Akhlaghpour
Jason Shepherd @jasonsynaptic.bsky.social · 17/02/2025
Feels weird to promote science right now but here’s a new review/opinion piece from the lab where we outline new insights about how Arc mediates long lasting synaptic plasticity and memory formation. 🧪🧠 kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
kwnsfk27.r.eu-west-1.awstrack.me
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Reposted by Hessam Akhlaghpour
Ipshita Zutshi @ipshitaz.bsky.social · 09/01/2025
It’s an incredible feeling to see something you’ve poured your heart into come to life. This work was born from my curiosity about hippocampal “cognitive tuning.” Our interpretation of the environment depends on our actions, constantly evolving as we pursue our goals www.nature.com/articles/s41...
nature.com
Hippocampal neuronal activity is aligned with action plans - Nature
Using high-density electrophysiological recordings, how internally generated cell assemblies are updated by action plans to meet external goals is explored.
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Reposted by Hessam Akhlaghpour
Philipp Brand @pbrand.bsky.social · 08/01/2025
I'm thrilled to be opening my own lab this Fall at the @maxplanck.de MPI for Brain Research in Frankfurt. The lab is going to investigate the neuronal and genetic underpinnings of behavioral evolution. We are hiring on all levels. Don't hesitate to share widely and reach out if interested.
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Reposted by Hessam Akhlaghpour
Wallace Marshall @wallaceucsf.bsky.social · 02/12/2024
Where does pattern come from inside cells? in this revised preprint, @aralbright.bsky.social Shows that regionalization of mRNA in a Stentor cell depends on dynein motors and the microtubule cytoskeleton doi.org/10.1101/2023...
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Reposted by Hessam Akhlaghpour
David Colaço @davidcolaco.bsky.social · 02/12/2024
@jonathannajenson.bsky.social and I will discuss @thehessam.bsky.social's work in the next session of our International Memory Reading Group
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Reposted by Hessam Akhlaghpour
Gualtiero Piccinini @gualtiero.bsky.social · 02/12/2024
@thehessam.bsky.social speculates that universal computation implemented by RNA is behind memory and cognition. It's a cool idea, though probably wrong. 1/
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Reposted by Hessam Akhlaghpour
Nicole Rust @nicolecrust.bsky.social · 02/12/2024
I admire trainees stepping up like this to talk about the big questions. @thehessam.bsky.social does a terrific job here talking about the nature of memory storage (synaptic vs not).
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Hessam Akhlaghpour @thehessam.bsky.social · 27/11/2024
I almost forgot how in the old twitter days, we could have productive exchanges in the comments. It’s happening again for me on bluesky - where I walk away from a discussion with learning something new to look up!
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Reposted by Hessam Akhlaghpour
PessoaBrain @pessoabrain.bsky.social · 27/11/2024
𝗪𝗵𝗮𝘁 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻 𝗶𝗺𝗽𝗹𝗲𝗺𝗲𝗻𝘁𝘀 𝘂𝗻𝗶𝘃𝗲𝗿𝘀𝗮𝗹 𝗰𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻? Maybe not neurons, perhaps RNA?? Great episode of Brain Inspired with Hessam Akhlaghpour. Do dynamical systems and/or RNNs implement universal computation? This discussion alone would be worth having. #neuroscience braininspired.co/podcast/199/
braininspired.co
BI 199 Hessam Akhlaghpour: Natural Universal Computation | Brain Inspired
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Hessam Akhlaghpour @thehessam.bsky.social · 26/11/2024
Since my early postdoc years, whenever my hands were busy with experiments but my mind was free, I’d listen to Brain Inspired. I would have been thrilled to know that I’d be on Paul’s show in the future, discussing what I think is the most exciting problem in biology. braininspired.co/podcast/199/
braininspired.co
BI 199 Hessam Akhlaghpour: Natural Universal Computation | Brain Inspired
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The Transmitter @thetransmitter.bsky.social · 26/11/2024
Could the brain’s computational abilities extend beyond neural networks to molecular mechanisms? Listen to Paul Middlebrooks's latest "Brain Inspired" podcast, in which he talks with @thehessam.bsky.social about how universal computation may have evolved via RNA mechanisms: bit.ly/4eQ4Idc
thetransmitter.org
Hessameddin Akhlaghpour outlines how RNA may implement universal computation
Could the brain’s computational abilities extend beyond neural networks to molecular mechanisms? Akhlaghpour describes how natural universal computation may have evolved via RNA mechanisms.
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Reposted by Hessam Akhlaghpour
Melanie Mitchell @melaniemitchell.bsky.social · 21/10/2024
New post on my Substack: aiguide.substack.com/p/the-llm-re...
aiguide.substack.com
The LLM Reasoning Debate Heats Up
Three recent papers examine the robustness of reasoning and problem-solving in large language models
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Hessam Akhlaghpour @thehessam.bsky.social · 13/10/2024
Are transformers/LLMs actually Turing-complete? (i.e., capable of computing anything a standard programming language can compute) I look at 16 papers on the subject. My conclusion is that, despite the claims, no one has proved this yet. lifeiscomputation.com/transformers...
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Hessam Akhlaghpour @thehessam.bsky.social · 02/07/2024
I need someone to make a comic where people decide the best way to solve a problem is to create an AI far smarter than them and have that solve it. Then that AI, being very smart, decides to create another smarter AI. This goes on recursively, forever, and nothing gets solved.
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