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Amelie Stein

@amelierocks.bsky.social
1.8K followers 892 following 96 posts

Scientist. Mom. Coffee snob. Protein nerd.

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Amelie Stein @amelierocks.bsky.social · 20/04/2026
Academia in a nutshell
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Amelie Stein @amelierocks.bsky.social · 26/01/2026
Big congratulations to Aleksandra Panfilova who defended her PhD last week! Aleks has been teasing apart models of protein interactions and consequences of mutations on these, preprint coming soon! She’s now looking for new opportunities in Estonia, so reach out to hear if you’re hiring 😊
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Amelie Stein @amelierocks.bsky.social · 19/01/2026
Annika raises many good points about the challenges with (not) “just putting the slides online”
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Amelie Stein @amelierocks.bsky.social · 25/11/2025
So looking forward to this meeting!
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Yury Bykov @yurabykov.bsky.social · 20/11/2025
Junior professor position at the University of Kaiserslautern! Our Department of Biology is seeking a colleague working with microalgae. This is a wonderful place to do wonderful science with great people! Please, repost :) Further details: jobs.rptu.de/jobposting/1...
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Amelie Stein @amelierocks.bsky.social · 20/11/2025
T’is the season When I scrape ice Off my saddle
Bike saddle covered in thousands of frozen droplets. Green grass and brown leaves in the background.
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Pause @ Real Scientists DE @realscientists.de · 19/11/2025
🧵 Thread👇 Heute Nachmittag im Fokus: Wissenschaftliche Karrierewege An der Uni wird oft nur das Karriereziel Professur diskutiert, aber der Weg dahin ist schwer, wenig planbar und die anderen Berufsoptionen sehr vielfältig (und zumeist sogar besser).
media.tenor.com
spongebob is writing on a piece of paper with a pen .
ALT: spongebob is writing on a piece of paper with a pen .
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Dr. Jey McCreight 🏳️‍⚧️🧬 @jeymccreight.bsky.social · 16/11/2025
I lament all the research and writing I never got to do because I was too busy fighting sex pests and institutionalized misogyny
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Oded Rechavi @odedrechavi.bsky.social · 14/11/2025
Adding citations of people who might review the paper
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 10/11/2025
One of my science heroes, Joan Brugge, talks about how science funding cuts are slowing their work on breast cancer prevention--share this widely www.facebook.com/60minutes/vi...
facebook.com
439K views · 15K reactions | Harvard researcher Joan Brugge says her work has the potential to prevent breast cancer, but she was notified last spring that her federal funding was terminated. “It was ...
Harvard researcher Joan Brugge says her work has the potential to prevent breast cancer, but she was notified last spring that her federal funding was terminated. “It was just like a gut punch. My...
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Amelie Stein @amelierocks.bsky.social · 08/11/2025
Fall is beautiful, even on gray days 🍂 🍁
Path by a creek strewn with leaves Ducks on the creek
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Meade Krosby @meadekrosby.bsky.social · 07/11/2025
Thinking only of Rosalind Franklin today, and what was stolen from her (and so many other female scientists alongside her).
science.org
Rosalind Franklin and the damage of gender harassment
Spurred by a recent report on sexual harassment in academia, our columnist revisits a historical case and reflects on what has changed—and what hasn’t
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Amelie Stein @amelierocks.bsky.social · 07/11/2025
My 11yo is more active in her Teams chats than I am in mine.
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Amelie Stein @amelierocks.bsky.social · 28/10/2025
Danish design cup
Royal Copenhagen cup filled with Lego
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Pedro Beltrao @pedrobeltrao.bsky.social · 28/10/2025
Looks like OpenFold3 has been formally released in a public "preview". Not quite on parity with AlphaFold3 on a few benchmarks shown, in particular for antibody interactions. All info on the github link. I am sure we will hear more about this from the developers github.com/aqlaboratory...
github.com
GitHub - aqlaboratory/openfold-3: OpenFold3: A fully open source biomolecular structure prediction model based on AlphaFold3
OpenFold3: A fully open source biomolecular structure prediction model based on AlphaFold3 - aqlaboratory/openfold-3
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 27/10/2025
The UNC Department of Biology is seeking a Director of Biology Teaching Labs, a key leadership role overseeing our undergraduate laboratory program. 1/n Learn more and apply here: unc.peopleadmin.com/postings/308...
unc.peopleadmin.com
Director of Biology Teaching Labs
The Director of Biology Teaching Labs provides leadership and direction in the management of the Biology Department's undergraduate laboratories and will be responsible for the undergraduate laborator...
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Mark Hamill @markhamillofficial.bsky.social · 27/10/2025
I have a very bad feeling about this...
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Laura Howes @laurahowes.bsky.social · 25/10/2025
Alternatively, lads, might be worth thinking about supporting the German car industry to remain viable in the future rather than locking them into a dying business model. But sure, you go off...
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Amelie Stein @amelierocks.bsky.social · 20/10/2025
Airplane sunrise is the reward for early departures. Looking forward to European RosettaCon 2025!
Blazing colourful sunrise seen through an airplane window
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Amelie Stein @amelierocks.bsky.social · 13/10/2025
Kiel
Kiel Marina, sail boatsPlanters along the marina Threemaster behind a large tree
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Izzy Jayasinghe @ijayas.bsky.social · 09/10/2025
Ah, a classic moment of @nature.com recognizing the scientific contributions of both genders: man and machine.
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Marcel Dickmanns | 🌿❄️🔬 @madic.bsky.social · 07/10/2025
You can get MSAs directly from AlphaFold DB now (alphafold.ebi.ac.uk). I also missed the FoldSeek implementation, which lets you search for structurally similar proteins direktly. This saves some clicking around. Neat!
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Andrew Iwaniuk @evoneuro.bsky.social · 09/10/2025
As I tell my students, if you arrived at a simple answer in biology you have done one of two things: arrived at the wrong answer or asked the wrong question
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Amelie Stein @amelierocks.bsky.social · 09/10/2025
Kindergarten teacher asks what I teach (biological sequence analyses), I try to explain. She turns to the 3yo and asks „What do you want to be when you grow up?“ Prompt and confident answer: „A butterfly 🦋!“
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Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 07/10/2025
The proteasome-substrate-shuttle protein UBQLN2 contains—like other quality control system proteins—a long region devoid of lysine (a lysine desert) Martin Grønbæk-Thygesen (from @rhp-lab.bsky.social) et al show that introducing K here causes ubiquitylation and degradation doi.org/10.1101/2025...
Fig. 1 – UBQLN2 is a conserved lysine-depleted protein. (A) Sequence comparison of
UBQLN2 orthologs in the indicated species. Intrinsically disordered regions in human
UBQLN2 based on MobiDB are shown as a blue bar. The domain organization based on the
SMART database is marked. Lysine residues are marked as black squares. (B) ESM-2
predictions of all possible single amino acid substitutions of human UBQLN2 presented as a
heat map. The wild-type residues are marked in blue. ESM-2 scores close to zero (light
yellow colors) indicate that the amino acid substitution is compatible with the ESM-2
language model, whereas negative scores (dark orange colors) indicate that the variant is
incompatible with the ESM-2 model. The domain organization (based on SMART) is aligned
above the map. Note that substitutions to lysine or cysteine in general appear detrimental, in
particular downstream of the UBL domain. (C) The AlphaFold2 predicted structured of
human UBQLN2 (AF-Q9UHD9-F1) (left panel). The UBL domain is colored blue, and the
UBA domain is colored orange and the STI1 regions green. Zoom in on the UBL domain
(right panel) with the lysine residues highlighted as stick representations and colored based
on the relative accessible surface area (rASA, dark red exposed; grey, buried).
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Elizabeth Wood, PhD @lizbwood.bsky.social · 06/10/2025
For every Nobel that goes to a criminally under-recognized woman scientist (Brunkow, Karikó), or fails to go (Candy Lee), a week of mourning and reform for an academic system wherein you can do Nobel-prize-worthy-work and still end up without a conceivable path to being a professor.
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Amelie Stein @amelierocks.bsky.social · 05/10/2025
Fun & action the local science museum #experimentarium
Small child standing by a goods transport model (essentially a very large rolling ball sculpture), next to a sign labelled København, putting orange balls onto the rails.
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Irina Bezsonova @irinabezsonova.bsky.social · 03/10/2025
This October I’m drawing one molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social Day 2/31 Prompt WEAVE N-terminal domain of a Fibrion - a building block of silk fiber produced by silkworms. Pdb: 3UA0 Next prompt is CROWN and I would love your suggestions!
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Amelie Stein @amelierocks.bsky.social · 03/10/2025
Some interesting thoughts on the Perspective Harper Raiken and I wrote over the summer
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Dr. Jens Foell @jensfoell.de · 23/03/2024
I don’t know who wrote this, but it’s absolutely perfect
• X-Men is about civil rights. If you didn't get that, you didn't get X-Men.
• Black Panther is about civil rights. If you didn't get that, you didn't get
Black Panther.
• Captain America literally fought the Nazis. He is the embodiment of fighting the alt-right. If you didn't get that, you didn't get Captain America.
• The Empire in Star Wars is fascist. The Rebel alliance is Anti-Fascist. If you didn't get that, you didn't get Star Wars.
• The Punisher isn't meant to be a role model for police or armed forces.
So much so that the writers of The Punisher made him actively speak out against it in a comic. If you didn't get that, you didn't get The Punisher.
• Deadpool is queer. He's pansexual. Fact. If you didn't get that you didn't get Deadpool.
• Star Trek is about equality for all genders, races, and sexualities. As early as the mid-60s it was taking a pro-choice stance and defending women's right to choose. One of its clearest themes is accepting different cultures and appearances
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Sarah Shammas @sarahshammas.bsky.social · 01/10/2025
Why are transcription factors disordered? Come join us in Oxford as a postdoc and we'll find out together! Help publish 3 mature projects, AND develop cool new single molecule fluorescence binding assays! biophysics transcription protein:DNA interactions my.corehr.com/pls/uoxrecru...
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Amelie Stein @amelierocks.bsky.social · 01/10/2025
Recruiting the next generation of bioinformatics students
Small child wearing a large blue t-shirt with “Bioinformatik” in big letters. Face covered with a heart for privacy.
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Greifflab @victorgreiff.bsky.social · 28/09/2025
We’re recruiting a PhD Fellow in Computational Systems Immunology. Work on large-scale immune receptor datasets and develop computational models in close collaboration with experimental labs. Apply here: www.jobbnorge.no/en/available...
jobbnorge.no
PhD Fellowship in Computational Systems Immunology (286608) | University of Oslo
Job title: PhD Fellowship in Computational Systems Immunology (286608), Employer: University of Oslo, Deadline: Wednesday, October 15, 2025
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Dr. Kat Napaaqtuk❄️ @napaaqtuk.bsky.social · 27/09/2025
Interesting episode of short wave about the origin of endometriosis. I really appreciate that they end with how uncertainty in NIH funding affects the future of their work. www.npr.org/2025/09/26/n...
npr.org
What causes endometriosis? Scientists are closer to finding out : Short Wave
Since the age of nine or ten, Katie Burns has had debilitating pain from endometriosis, a condition where tissue resembling the uterine lining grows outside the uterus. For years, Katie was in the dar...
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John Lees @johnlees.bacpop.org · 17/09/2025
The EMBL PhD programme is open until 13th October (entry ~Sep 2026): www.embl.org/about/info/e... We have three positions in microbial genomics at EMBL-EBI, including one in my group. Please do apply, or if you know anyone that would be interested pass on to them
embl.org
EMBL International PhD Programme – Unique in the world and waiting for you!
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Amelie Stein @amelierocks.bsky.social · 21/09/2025
Job opportunities at an absolutely amazing place for molecular biology 🧫
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Amelie Stein @amelierocks.bsky.social · 21/09/2025
Almost done, just need to add a bit of background.
Partially complete 1500 piece puzzle of an underwater scene. Large sea turtle and some rocks done, lots of water missing.
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Amelie Stein @amelierocks.bsky.social · 20/09/2025
Different supervision task today 🍿
Gloved hands scooping popcorn out of a big popcorn machine
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Amelie Stein @amelierocks.bsky.social · 18/09/2025
Deadline extended - last chance, second edition!
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Amelie Stein @amelierocks.bsky.social · 18/09/2025
Cool project with the Pless lab on disease-associated variants in a membrane protein, NALCN, that needs to be in complex to function. Most of our computational work was done by PhD student Aleks Panfilova.
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Bjørn Panyella Pedersen @bjornppedersen.bsky.social · 16/09/2025
Interested in structural biology, membrane proteins, biophysics and working to understand hormone transport in plants?☘️🔬👩‍🔬🧪 We have an open PhD position: - 3 years fully funded. - Details and application link: www.linkedin.com/posts/plant-... Please repost 💚
linkedin.com
🚀 Exciting PhD opportunity in structural biology & plant science! 🌱 PhD Position – Structural and Functional Studies of Plant Membrane-Protein Transporters 📍 Molecular Biology & Genetics -… ...
🚀 Exciting PhD opportunity in structural biology & plant science! 🌱 PhD Position – Structural and Functional Studies of Plant Membrane-Protein Transporters 📍 Molecular Biology & Genetics - Aarhus Un...
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Anthony Gitter @anthonygitter.bsky.social · 11/09/2025
The journal version of "Biophysics-based protein language models for protein engineering" with @philromero.bsky.social is live! Mutational Effect Transfer Learning (METL) is a protein language model trained on biophysical simulations that we use for protein engineering. 1/ doi.org/10.1038/s415...
doi.org
Biophysics-based protein language models for protein engineering - Nature Methods
Mutational effect transfer learning (METL) is a protein language model framework that unites machine learning and biophysical modeling. Transformer-based neural networks are pretrained on biophysical ...
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Amelie Stein @amelierocks.bsky.social · 08/09/2025
🎯
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FMI science @fmiscience.bsky.social · 08/09/2025
🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬 Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
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Amelie Stein @amelierocks.bsky.social · 08/09/2025
One of those days when Copenhagen is trying to play San Francisco 🌫️ Fortunately we got to keep the trains.
Tall building vanishing in fog, train tracks with train approaching
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Decay @decay.rantspace.org · 06/09/2025
"We can and should reject that AI output is ‘good enough,’ not only because it is not good, but also because there is inherent value in thinking for ourselves."
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Ben Engel @cellarchlab.com · 26/08/2025
BIG NEWS!! We will be hiring a new professor with 25 years of endowed funding at the @biozentrum.unibas.ch @unibas.ch, focused on using biophysics and structural biology to explore climate-related fundamental science topics. Come start an innovative research cluster with us! 🧪🔬🧶🧬🌾🌍
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Amelie Stein @amelierocks.bsky.social · 04/09/2025
Successfully taught my first bioinformatics class in Danish 🇩🇰 Based on feedback, the most helpful bit was rather language-Independent, when I said that affine gap scores are kinda like Affinity in Magic The Gathering 🧙‍♀️ 📜
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Amelie Stein @amelierocks.bsky.social · 01/09/2025
A very relatable rant on why manuscript revisions can be frustrating. And it doesn’t even mention „you should have cited these 7 tangentially related articles, all written by the same author“ 📜
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Amelie Stein @amelierocks.bsky.social · 31/08/2025
This is where German clearly was much easier. To this day I can find myself in an English audiobook and realise „oh that’s how you pronounce it“ 😅
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