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Taylor priest

@taylorpriest.bsky.social
520 followers 357 following 208 posts

NOMIS-ETH fellow at Institute of Microbiology and Center of Origin and Prevalence of Life, ETH Zurich | microbial ecologist interested in diversification, evolution and mobile genetic elements | Parent of a beautiful Briard | food and fitness enthusiast

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Taylor priest @taylorpriest.bsky.social · 06/10/2026
Our new preprint is out! We show that genomically discrete and ecologically cohesive subspecies are a common feature in the global ocean microbiome, and represent a fundamental level at which ecological and evolutionary forces act to shape microbial diversity www.biorxiv.org/content/10.6...
biorxiv.org
Genomically and ecologically cohesive subspecies as biologically meaningful units in the global ocean microbiome
Microbial diversity is organised into operationally defined species. However, it remains unclear whether these, or finer-scale groups represent biologically meaningful units in natural communities. He...
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Microbiome Research Lab, ETH Zürich @microbiomeresearch.bsky.social · 06/10/2026
What is the fundamental level at which ecology and evolution shape microbial diversity? Our new preprint shows that genomically discrete and ecologically cohesive subspecies are a common feature in the global ocean microbiome - www.biorxiv.org/content/10.6...
biorxiv.org
Genomically and ecologically cohesive subspecies as biologically meaningful units in the global ocean microbiome
Microbial diversity is organised into operationally defined species. However, it remains unclear whether these, or finer-scale groups represent biologically meaningful units in natural communities. He...
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Taylor priest @taylorpriest.bsky.social · 26/09/2026
Congrats Lauren 🥳very nice study!
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Lauren Queiss @lqueiss.bsky.social · 24/09/2026
What happens when two viruses coinfect the same host? Check out the first publication of my PhD, where we describe two new viruses from an extremophilic system! www.nature.com/articles/s42...
nature.com
Two coinfecting archaeal viruses provide insights into virus-virus interactions - Communications Biology
Communications Biology - Two coinfecting archaeal viruses provide insights into virus-virus interactions
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Taylor priest @taylorpriest.bsky.social · 26/09/2026
Very cool work!
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Taylor priest @taylorpriest.bsky.social · 26/09/2026
Cross-feeding enables robust coexistence between four bacterial species pnas.org/doi/10.1073/pnas.2607664123
pnas.org
Cross-feeding enables robust coexistence between four bacterial species | PNAS
Resource supply is generally considered a dominant driver of microbial diversity. Here, using a four-species bacterial consortium, we asked whether...
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Evgenii Protasov @evgenii-protasov.bsky.social · 30/08/2026
Synergistic degradation of fucoidans in the ocean #microbiology #algae #polysaccharides #MicroSky @nature.com www.nature.com/articles/s41...
nature.com
Synergistic degradation of fucoidans in the ocean - Nature
Efficient degradation of fucoidans depends on complementary bacterial guilds that cooperatively break backbone and side-chain sugars, revealing a conserved, globally relevant mechanism that shapes mar...
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Noah Houpt @noahhoupt.bsky.social · 25/08/2026
Thrilled to see this project officially published in ISMEJ! We showed that filamentous prophages frequently acquired repressor mutations causing hyperactivity which, in turn, drove the evolution of phage resistance with pleiotropic consequences. academic.oup.com/ismej/advanc...
academic.oup.com
Mutations in filamentous bacteriophages spark eco-evolutionary feedbacks in Pseudomonas aeruginosa
Abstract. Microbial populations strongly shape their environment, which can re-route adaptation toward organism-generated fitness optima. However, the cond
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Taylor priest @taylorpriest.bsky.social · 25/08/2026
🚨Interested in methane cycling or carbon flow in sediments? In our new paper, we establish a link between... polysaccharide degradation 🔗fermentation🔗methanogenesis🔗methane oxidation... In anoxic lake sediments academic.oup.com/ismecommun/a... Congrats to @bledinadede.bsky.social for leading this
academic.oup.com
Active microbial communities and their extrachromosomal elements link organic matter degradation to methane cycling in anoxic sediments
Abstract. Anaerobic carbon transformation in freshwater sediments drives substantial methane emissions globally, yet the microbial taxa linking complex car
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Taylor priest @taylorpriest.bsky.social · 23/08/2026
A nice perspective piece that touches upon ecological turnover and evolutionary change, how this manifests in microbiomes and how we are trying to assess this in time-series data journals.asm.org/doi/10.1128/...
journals.asm.org
Rethinking evolutionary inference in metagenomic time series | mSystems
A common expectation in modern microbiome research is that microbes evolve rapidly (1). Whether in response to pollution, climate change, or host interaction, it is often assumed that high turnover ra...
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Emmanuele Severi @emmseveri.bsky.social · 20/08/2026
#microsky #phagesky T7’s phospho-bombing of host proteins overcomes (-whelms) E. coli #phage defence mechanisms www.nature.com/articles/s41...
nature.com
Pervasive phosphorylation by phage T7 kinase disarms bacterial defences - Nature
The T7 bacteriophage deactivates bacterial defence systems through T7K phosphorylation of nearly all host and phage proteins during infection.
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Taylor priest @taylorpriest.bsky.social · 06/08/2026
Huge fan of this! A new stats package (DABEST) brings estimation graphics to multi group comparisons, focusing on effect sizes, confidence Intervals and bootstrap-based uncertainties. Its time to move on from ANOVA www.nature.com/articles/s41...
nature.com
Getting over ANOVA: estimation graphics for multi-group comparisons - Nature Methods
Nature Methods - Getting over ANOVA: estimation graphics for multi-group comparisons
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Cameron Thrash @jcamthrash.bsky.social · 30/07/2026
Declining coccolithophore blooms in the North Atlantic and Western Barents Sea www.science.org/doi/full/10.... #jcampubs 🌊
science.org
Declining coccolithophore blooms in the North Atlantic and Western Barents Sea
Satellite observations reveal substantial decreases in coccolithophore blooms across the North Atlantic and Barents Sea.
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Taylor priest @taylorpriest.bsky.social · 14/07/2026
Microbial anaerobic digestion communities converge on metabolic functions and metabolite profiles despite variability in taxonomic composition - academic.oup.com/ismej/articl...
academic.oup.com
Environmental selection constrains metabolic network architecture despite taxonomic turnover in anaerobic digestion communities
Abstract. Microbial ecosystems often sustain stable metabolic functions despite pronounced taxonomic turnover, yet the mechanisms underlying such reproduci
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Taylor priest @taylorpriest.bsky.social · 29/06/2026
Mobile genetic elements shape microbial diversity and functions in thawing permafrost soils www.nature.com/articles/s41...
nature.com
Mobile genetic elements shape microbial diversity and functions in thawing permafrost soils - Nature Microbiology
An 8-year soil meta-omic time series shows how mobile genetic elements shape permafrost microbial diversity and impact a range of functions, including carbon and nutrient cycling.
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Simon Roux @simrouxvirus.bsky.social · 29/06/2026
🚨New paper alert 🚨 Here we tried to leverage an (incredible) metagenome time-series to better understand MGE diversity and activity in soil across decade(s). @scbagby.bsky.social has an amazing thread about this work with all the details - bsky.app/profile/scba...
nature.com
Mobile genetic elements shape microbial diversity and functions in thawing permafrost soils - Nature Microbiology
An 8-year soil meta-omic time series shows how mobile genetic elements shape permafrost microbial diversity and impact a range of functions, including carbon and nutrient cycling.
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Cameron Thrash @jcamthrash.bsky.social · 29/06/2026
Cyanobacterial flocculation as a defence against bacterial predation academic.oup.com/ismej/advanc... #jcampubs
academic.oup.com
Cyanobacterial flocculation as a defence against bacterial predation
Abstract. Many cyanobacteria are capable of flocculation: the formation of floating linked assemblages of many thousands of cells. Flocculation is a highly
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Taylor priest @taylorpriest.bsky.social · 21/06/2026
In marine microbial studies, we typically filter seawater through a 0.22 micron filter...have you ever wondered how many cells and of what taxa pass through these filters ? This study provides some new insights on this - onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
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Taylor priest @taylorpriest.bsky.social · 15/06/2026
Very nice study integrated metagenomics, metatranscriptomics and geochemistry to gain insights into microbial communities and methane production in a temperate wetland ecosystem - journals.asm.org/doi/10.1128/... #MicroSky #MicroEco #EcoEvo
journals.asm.org
Mapping the soil microbiome functions shaping wetland methane emissions | mSystems
Soil microbial ecology is increasingly recognized as essential to climate mitigation, but realizing its full potential requires shifting from static genome inventories to dynamic assessments of microbial activity. This study shows that methane-cycling microbes exhibit stable, depth-stratified expression patterns, even in response to major redox and flooding shifts, undermining assumptions that water-table manipulations common in wetland management can alone reduce methanogenesis. Instead, methane cycling is shaped by spatially organized, transcriptionally active networks involving not only methanogens but also methanotrophs, fermenters, and iron reducers. These findings expose the limitations of genome-only models and highlight the need for soil diagnostics that capture in situ activity. Together, we provide a foundation for developing activity-based microbiome tools, embedding microbial functions into Earth system models, and designing interventions that move beyond “single-lever” strategies and instead work with the structure and dynamics of microbial communities as complex, layered systems.
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Brian J. Enquist @bjenquist.bsky.social · 11/06/2026
Fifty years since a simple equation described the chaos of biology 🧪🌐 www.nature.com/articles/d41...
nature.com
Fifty years since a simple equation described the chaos of biology
An exploration of chaos theory in population dynamics showed that unpredictable systems can often be modelled using surprisingly simple mathematics.
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Taylor priest @taylorpriest.bsky.social · 11/06/2026
How is the diversity of microbes structured across the global oceans ? Check out our latest paper, spearheaded by @jonas-bio.bsky.social and Dominic Eriksson, that addresses this - www.cell.com/cell-host-mi...
cell.com
Variations in the latitudinal diversity gradients of the ocean microbiome
Eriksson et al. conduct a global marine microbiome diversity analysis and demonstrate how the surface ocean latitudinal diversity gradient is disproportionately shaped by a few species-rich taxa. Mask...
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Taylor priest @taylorpriest.bsky.social · 11/06/2026
Very happy to have been given the opportunity to contribute to this great study on the spatial structuring of microbial biodiversity in the oceans #MicroSky #Microecoevo www.cell.com/cell-host-mi...
cell.com
Variations in the latitudinal diversity gradients of the ocean microbiome
Eriksson et al. conduct a global marine microbiome diversity analysis and demonstrate how the surface ocean latitudinal diversity gradient is disproportionately shaped by a few species-rich taxa. Mask...
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Jonas Schiller @jonas-bio.bsky.social · 10/06/2026
Our new paper „Variations in the latitudinal diversity gradients of the ocean microbiome“ was just published in @cp-cellhostmicrobe.bsky.social 🥳 We present a global analysis of prokaryotic #biodiversity in the surface and mesopelagic layers of the ocean 🦠🌊 www.cell.com/cell-host-mi...
cell.com
Variations in the latitudinal diversity gradients of the ocean microbiome
Eriksson et al. conduct a global marine microbiome diversity analysis and demonstrate how the surface ocean latitudinal diversity gradient is disproportionately shaped by a few species-rich taxa. Mask...
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Joshua Weitz @joshuasweitz.bsky.social · 29/05/2026
Viruses are highly abundant in the oceans, but there is one place you won't typically find them: in global ocean ecosystem models... until now. Introducing "vDarwin", an explicit integration of viruses into the MITgcm/Darwin global ecosystem framework: www.biorxiv.org/content/10.6... a 🧵
Integration of a model of viral lysis, shunt and shuttle in a large scale ocean circulation model. (A) Schematic of the large scale ocean circulation model (MITgcm): major surface ocean circulation patterns and the schematic of the advection/diffusion are represented. Note that vertical grid spacing increases with depth (i.e., layers become thicker). (B) Simplified ecosystem represented in the study. For simplicity nitrogen remineralization to nitrite and nitrate and mortality fluxes to DOM and POM are not represented. (C) Schematic of the vDarwin ecosystem model integrated in the large scale circulation model. It represents a simplification of the ecosystem presented in (B) assuming that N is the limiting nutrient. It includes the growth of a single phytoplankton type, viral lysis, zooplankton grazing, the viral shunt and shuttle and remineralization (note that remineralizing bacteria are not explicitly represented).
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Marie C. Schölmerich @mschoelmerich.bsky.social · 28/05/2026
We think that EET may be an overlooked respiratory strategy in peatlands with implications for CH₄ emissions. Preprint: tinyurl.com/5d7p4cwn Congrats to @gfiorito.bsky.social and the whole team: @taylorpriest.bsky.social @bledinadede.bsky.social, Hanna Zehnle et al.! #MicroSky #Microbiology
tinyurl.com
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Taylor priest @taylorpriest.bsky.social · 28/05/2026
While I feel so lucky to have had great supervisors so far, this is, unfortunately, not commonplace!
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Taylor priest @taylorpriest.bsky.social · 28/05/2026
Therefore, I think it is your responsibility as a supervisor to do everything you can to make sure that you're creating a supportive and constructive environment that will allow individuals to learn and grow in the way that best suits them!
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Taylor priest @taylorpriest.bsky.social · 28/05/2026
supervision is at the core of every person's journey in science, and has a significant influence not only on the perspectives that we develop, the opportunities we are exposed to and our career paths but also on our mental health.
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Taylor priest @taylorpriest.bsky.social · 28/05/2026
Unfortunately, the largest supervisory roles are designated solely based on scientific merit without a consideration for how such individuals may be as supervisors, role models and, ultimately, leaders. Which is pretty crazy, considering that...
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Taylor priest @taylorpriest.bsky.social · 28/05/2026
A survey of 2600 early-career researchers provides insights into good and bad practices of supervision - www.biorxiv.org/content/10.6... So valuable! I think supervision is, unfortunately, largely an after thought in scientific research...🧵
biorxiv.org
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Susie Grigson @susiegriggo.bsky.social · 20/05/2026
Beyond thrilled that our paper ‘Co-migration of hundreds of microbial species over metres drives selection and promotes non-motile hitchhikers’ has been accepted in Nature Communications! 🎉🦠 (1/n) www.nature.com/articles/s41...
nature.com
Co-migration of hundreds of microbial species over metres drives selection and promotes non-motile hitchhikers - Nature Communications
Migration of microbial communities is poorly understood. Here, the authors use a meso-tube assay to show that hundreds of microbial species co-migrate over metre scales via chemotaxis, which restructu...
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Leigh Anne Riedman @fossils.bsky.social · 20/05/2026
Excited to say that my new paper with @maxlechte.bsky.social (and others not on bluesky) has come out in @nature.com! Study of sediments, geochemistry and fossils from rocks 1.75 to 1.4 billion years old indicate that the oldest known #eukaryotes were aerobic and benthic! #protists rdcu.be/fjNgL
rdcu.be
Early fossil eukaryotes were benthic aerobes
Nature - Integrated palaeontological, sedimentological and geochemical analyses of ancient rocks from Australia show that early eukaryotes were largely restricted to oxygenated benthic habitats,...
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Taylor priest @taylorpriest.bsky.social · 16/05/2026
Well damn, thats certainly a different use. Very cool!
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Taylor priest @taylorpriest.bsky.social · 14/05/2026
Very interesting read and great study - Genome wide sweeps creat ecological units in the human gut microbiome #MicroSky #Microevo #Microbiome www.nature.com/articles/s41...
nature.com
Genome-wide sweeps create ecological units in the human gut microbiome - Nature
Genome-wide selective sweeps commonly occur in the human gut microbiome and can spread across the world within decades to produce epidemic-like population structures.
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Taylor priest @taylorpriest.bsky.social · 04/05/2026
A new method for inference and tracking the transmission of strains in metagenomes #MicroSky #MicroEco www.nature.com/articles/s41...
nature.com
Strain-level transmission inference across multi-kingdom metagenomic data using TRACS - Nature Microbiology
The TRACS algorithm tracks bacteria, viruses and parasites in metagenomic or population sequencing data, detecting microbial transmission even when multiple strains coexist within a host.
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Samir Giri @isamirgiri.bsky.social · 24/04/2026
Cool paper👇 In a microbial community, each species changes its proteome (what proteins it expresses) to do a more specialised metabolic job, so overall functional overlap between species goes down...
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Taylor priest @taylorpriest.bsky.social · 24/04/2026
Yeah good point! Metabat2 doesn’t do that to my knowledge. I agree that it would have been nice for them to emphasise the quality of the LR results, especially given that the field is slowly progressing in that direction
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Taylor priest @taylorpriest.bsky.social · 23/04/2026
I think we're almost there for lower complexity communities! Still have a way to go for more complex communities though, which will require much deeper sequencing and continued development of LR assembly algorithms. Recently developed tools (myloasm & meta-mdbg) are showing promise
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Cameron Thrash @jcamthrash.bsky.social · 23/04/2026
Our first collaboration with the Levine lab! Defining metabolic niches for marine microbial heterotrophs www.science.org/doi/full/10.... #jcampubs 🌊
science.org
Defining metabolic niches for marine microbial heterotrophs
Understanding carbon cycling requires simplifying bacterial diversity into functional groups defined by genetic signatures.
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Taylor priest @taylorpriest.bsky.social · 23/04/2026
It is impressive, but perhaps expected. I would anticipate much longer contigs in the LR data, which would be richer in information for a binning algorithmn. I reckon the chimeric contigs in SR MAGs are likely short and fragmented
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Taylor priest @taylorpriest.bsky.social · 23/04/2026
Absolutely, that is no surprise at all. We only measure contamination based on single copy markers, and they can easily underestimate true contamination.
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Taylor priest @taylorpriest.bsky.social · 23/04/2026
#MicroSky #MicrobiomeSky
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Microbiome Research Lab, ETH Zürich @microbiomeresearch.bsky.social · 23/04/2026
How diverse are E. coli capsules? In collaboration with @mucosalimmunology.bsky.social we mapped this uncharted diversity in >66k genomes with a new tool, kTYPr, paving the way to capsule-targeted therapies and vaccines www.nature.com/articles/s41... @eth-microbiology.bsky.social
nature.com
In silico typing maps the natural diversity of Escherichia coli transporter-dependent capsules - Nature Microbiology
Escherichia coli ABC transporter-dependent capsule gene analysis alongside the development and application of the kTYPr in silico capsule typing tool uncovers E. coli capsule diversity across environm...
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Taylor priest @taylorpriest.bsky.social · 23/04/2026
Maybe I missed it, but it is also unclear from the description of chinerism, how much is derived from different strains of the same species and different species? The former is what we expect - MAGs represent sample level populations
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Taylor priest @taylorpriest.bsky.social · 20/04/2026
I think a major problem we have in science is the undervaluation of statistics. The expectation is that you run a test and show that p<0.05, but im my opinion that is not adequate and we need to do better!
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Taylor priest @taylorpriest.bsky.social · 20/04/2026
In addition to this, you should always look at the effect size (i.e. the magnitude of difference or effect) and view this in the context of what it means biologically
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Taylor priest @taylorpriest.bsky.social · 20/04/2026
When interpreting p values, it's important to understand a) p values are continuous values, they measure the departure of a test statistic away from the null, b) with large datasets, the chance that you will receive p<0.05 is very high, not necessarily because there is a significant difference...
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Taylor priest @taylorpriest.bsky.social · 20/04/2026
It is crazy that in 2026, major research findings published in high impact journals are still being built on a dichotomous view of p-values without any consideration of effect sizes or biological context! Just because you get p < 0.05 that doesn’t mean it is biologically significant....
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Taylor priest @taylorpriest.bsky.social · 19/04/2026
Seasonality drives temporal niche partitioning of pelagic prokaryotes academic.oup.com/ismej/articl...
academic.oup.com
Seasonality drives temporal niche partitioning of pelagic prokaryotes
Abstract. Prokaryote seasonality is well documented in lakes, coastal areas, and inland seas, yet microbial annual periodicity in diverse open ocean settin
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Evgenii Protasov @evgenii-protasov.bsky.social · 19/04/2026
Illuminating the newly produced viruses within the virosphere with bioorthogonal noncanonical amino acid tagging and single-virus genomic sequencing technologies #microbiology #virus #viruses #MicroSky @isme-microbes.bsky.social doi.org/10.1093/isme...
doi.org
Illuminating the newly produced viruses within the virosphere with bioorthogonal noncanonical amino acid tagging and single-virus genomic sequencing technologies
Abstract. Marine viruses impact biogeochemical cycles through cell lysis, releasing organic matter and nutrients that fuel ocean productivity. Identifying
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