Sign in

Drug Discovery Unit, University of Dundee

@ddu-dundee.bsky.social
369 followers 527 following 89 posts
PostsRepliesMedia
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 17/09/2026
Happy New Paper Day! We're excited to share this @natchembio.nature.com on #SmallMoleculeInhibitors of NorA, an efflux pump that is an important mediator of #antibioticresistance in #MRSA. It pumps antibiotics out , lowering their concentration in the cell. doi.org/10.1038/s415...
doi.org
Small-molecule inhibitors block NorA efflux by conformational trapping - Nature Chemical Biology
Multidrug efflux pumps expel antibiotics, contributing to antibiotic resistance. Now, high-throughput screening and structural characterization reveal an inhibitor of Staphylococcus aureus efflux pump...
112
Reposted by Drug Discovery Unit, University of Dundee
Guðjón Ólafsson @godjohn.bsky.social · 15/07/2026
A fully funded PhD position is now open in my lab at the University of Iceland. We are looking for an ambitious researcher to join us in Reykjavik, Iceland to work on targeted protein degradation. Interested? You are welcome to contact me or check out: 🔗https://euraxess.ec.europa.eu/jobs/452601
086
Reposted by Drug Discovery Unit, University of Dundee
Manu De Rycker @mdr-ddu.bsky.social · 01/06/2026
Our #Trypanosoma cruzi single-cell atlas paper is now available online! Great work by Ross Laidlaw and Marta Garcia Sanchez, and excellent collaboration with Thomas Otto! rdcu.be/flOWR @ddu-dundee.bsky.social, @dundeeuni.bsky.social #single-cell, #Chagas, #atlas, #trypanosome, #scRNA-seq 🧪🔬
rdcu.be
Trypanosoma cruzi cell atlas as a single-cell resource for understanding parasite population heterogeneity and differentiation
Nature Communications - Here, Laidlaw, Garcia Sanchez and colleagues present a single-cell atlas for Trypanosoma cruzi, an important protozoan pathogen, providing insights into cell heterogeneity,...
086
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 26/05/2026
Hi sky-pals! We here at DDU towers hope you are keeping cool in these hot May days! Let's continue our #BookReviews as part of #WomensHealthMonth, give you something to read over your lunch break! Today we're reading Meghan Rabbitt’s The New Rules of Women’s Health #DDUat20
141
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 22/05/2026
Happy Friday y'all! Hope you all had a good week. We've got some more #BookReviews for you for #WomensHealthMonth. This morning we are talking about "Invisible Women - Exposing data bias in a world designed for men" by @ccriadoperez.bsky.social #DDUat20 #HealthEquity #WomenInSTEM #InvisibleWomen
132
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 21/05/2026
Morning skypals! Tea-break time seems like a good time for a book review - how about it? We will start with Medical Bondage, by Deirdre Cooper Owens, an American historian & reproductive rights activist #womenshealthmonth #DDUat20 #BookReview
131
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 18/05/2026
NHS urged to update website after renaming polycystic ovary syndrome (as polyendocrine metabolic syndrome (PMOS) - missing from the headline) #womenshealthmonth #DDUat20 #PMOS www.theguardian.com/society/2026...
theguardian.com
NHS urged to update website after renaming polycystic ovary syndrome
Charity says absence of new name polyendocrine metabolic syndrome (PMOS) could cause confusion
011
Reposted by Drug Discovery Unit, University of Dundee
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 18/05/2026
Mycobacteriophage TM4 requires XylR for successful infection in Mycobacterium smegmatis mc2155 www.biorxiv.org/content/10.64898/20…
031
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 18/05/2026
Good morning skypals! We hope you all have a relaxing weekend and are looking forward to a great week! This week we have some excellent book reviews to share for #WomensHealthMonth What have you got coming up?
121
Reposted by Drug Discovery Unit, University of Dundee
Chemistry World @chemistryworld.com · 14/05/2026
The difference between isoleucine and valine is not that great, which made isoleucine the ideal target for substitution, but simply replacing isoleucine with valine didn’t work as well as hoped. Read on: www.chemistryworld.com/news/strippe...
chemistryworld.com
Stripped down bacterium functions with one less amino acid than the rest of life on Earth
Deep learning models used to understand how isoleucine could be replaced in proteins without disrupting their structures
043
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 13/05/2026
Got a science shaped hole in your Monday evening? Why not pop along to #PintofScience! Rosie Street-Jeakings & Christopher Bailey are both talking about #malaria research. Get your tickets at the link! pintofscience.co.uk/event/drugs-...
pintofscience.co.uk
Drugs and Bugs: The Fight for Global Health
Why does disease only target certain people? How do we make new treatments for that disease? Does your postcode alter the treatment you get? These are all …
012
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 12/05/2026
#womenshealthmonth #threepillarsofwomenshealth
101
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 12/05/2026
Congratulations to Prof Doreen Cantrell on her election to US-based National Academy of Sciences @nasonline.org #WomenInScience www.biodundee.co.uk/science-city...
biodundee.co.uk
Dundee scientist recognised with top international honour | Welcome to Bio-Dundee
A pioneering University of Dundee academic has received international recognition after being elected to one of the world’s foremost scientific institutions.
022
Reposted by Drug Discovery Unit, University of Dundee
Wellcome Sanger Institute @sangerinstitute.bsky.social · 12/05/2026
Women’s health has long been underfunded and understudied. This Women’s Health Month, see how our researchers are using genomics to uncover new insights to improve outcomes for women worldwide. Read more: sangerinstitute.blog/2026/05/12/way…
The Pelvic Matters team with their zine.
032
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 12/05/2026
In March 2025, we hosted an #Endometriosis Networking Workshop with experts from across the field. We’re excited to share the resulting white paper! A huge thanks to all who contributed to these vital discussions. Read here: www.linkedin.com/posts/possib... #DrugDiscovery #WomensHealth #DDUat20
linkedin.com
Possible Strategies for Drug Discovery for Endometriosis | Drug Discovery Unit, University of Dundee
In March 2025, we convened an Endometriosis Networking Workshop, bringing together academics, clinicians, industry leaders, and venture capitalists to collaboratively explore how we can advance drug d...
002
Reposted by Drug Discovery Unit, University of Dundee
Biochemical Society @biochemsoc.bsky.social · 11/05/2026
Final call for anyone interested in an opportunity to join our editorial boards and journals! Applications lose at midday today, 11 May 2026. Help shape the future of Society publishing, we are looking forward to hearing from you. Apply here for our current Spring cycle: ow.ly/1VvK50YXcH7
Top view of five people collaborating around a table with laptops and papers, promoting editorial board opportunities at Biochemical Society.
We're looking for people to become our Associate Editors and Editorial Board members. Open for applications. Visit our website to apply
001
Reposted by Drug Discovery Unit, University of Dundee
PrecisionLife @precisionlife.bsky.social · 08/05/2026
New data presented at #EEC2026 identified and validated novel reproducible genetic risk factors associated with endometriosis across UK & US patient cohorts. 🎥 Watch the presentation: precisionlife.com/womens-healt... 📜 Read the preprint: www.medrxiv.org/content/10.1... #WomensHealthMonth
precisionlife.com
Endometriosis Genetic Risk Factors Identified and Validated
Watch Krystyna Taylor present PrecisionLife’s validation of genetic risk factors for endometriosis using combinatorial analysis.
011
Reposted by Drug Discovery Unit, University of Dundee
Alzheimer's Association @alzassociation.bsky.social · 02/05/2026
Almost two-thirds of Americans with Alzheimer's are women. By adopting these healthy habits, we can all protect our brain health: alz.org/healthyhabits. #WomensHealthMonth
052
Reposted by Drug Discovery Unit, University of Dundee
AAMC @aamc.org · 06/05/2026
When Elizabeth Blackwell became the first woman in the U.S. to earn an MD in 1849, her male classmates didn’t expect her to change medicine forever. This #WomensHealthMonth, explore what Blackwell’s legacy can teach us, 175+ years later.
aamc.org
A Lady Alone: The story of Elizabeth Blackwell, MD, the first female physician in the United States
Admitted to medical school on a whim, Blackwell became a dominant force in the fight for women’s health care and for the education of women physicians.
032
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 10/05/2026
Relevant to #WomensHealthMonth!
043
Reposted by Drug Discovery Unit, University of Dundee
Nature @nature.com · 10/05/2026
Experienced researchers are less likely to produce ‘disruptive’ science than are those just starting their careers, finds an analysis of scientific papers published by 12.5 million researchers over 60 years go.nature.com/3Pb1lqg
go.nature.com
Early-career researchers do more ‘disruptive’ science than veterans
Nature - Analysis of papers from millions of scientists shows that older researchers tend to stick with ideas from their past.
14613
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 04/05/2026
We would like to say in advance, for the purposes of these posts "women's health" encompasses people who were assigned female at birth. This is a scientific classification not a sociological one and nothing in here negates the lived experiences of trans people. #WomensHealthMonth
120
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 04/05/2026
Good morning sky-friends! We hope you are well on this lovely #mayday bank holiday! May is #WomensHealthMonth and we have lots of interesting things we want to talk about!
041
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 25/04/2026
"Since 2010, the DDU malaria team, working with academic and industry partners, has been dedicated to discovering new medicines to treat and prevent malaria. One major success has been the discovery of Cabamiquine (DDD498)..." #NowWeCanNowWeMust #WorldMalariaDay #Research #EndMalaria #DDUAT20
232
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 25/04/2026
“Over the past two years, we have also been working with @novartis.bsky.social to develop a new drug aimed at stopping malaria relapses. These relapses are caused by a form of malaria that can hide in the liver for months or even years after infection..." #NowWeCanNowWeMust #WorldMalariaDay
221
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 25/04/2026
Children under five and pregnant women are the most at risk from malaria, accounting for the majority of the approximately 600,000 deaths each year worldwide. #NowWeCanNowWeMust #WorldMalariaDay #EndMalaria #GlobalHealth #HealthEquity #DrugDiscovery #InfectiousDiseases #PublicHealth #DDUAT20
133
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 23/04/2026
#ICYMI here is @mdr-ddu.bsky.social talking about Chagas Disease #DrugDiscovery for #WorldChagasDisease www.youtube.com/watch?v=TIj3...
youtube.com
World Chagas Disease Day | Dr Manu De Rycker on Chagas Drug Discovery
YouTube video by Drug Discovery Unit Dundee
031
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 15/04/2026
ICYMI yesterday... Here is @mdr-ddu.bsky.social's blog post on the importance of continuing the fight against #ChagasDisease #drugdiscovery #GlobalHealth www.sfc.ac.uk/inside-the-u...
sfc.ac.uk
Inside the University of Dundee’s long‑term fight against Chagas disease - Scottish Funding Council
World Chagas Disease Day acts as a reminder of a global health challenge that often goes unnoticed. Manu De Rycker shares what his team are doing to combat this disease.
010
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 14/04/2026
Because in diseases like Chagas, leaving even a single parasite behind isn’t an option. At DDU, we developed a washout assay to determine if compounds can achieve complete parasite clearance. #DrugDiscovery #NTD #ChagasDisease #GlobalHealth #ScientificInnovation #NeglectedDiseases #Research
An image of intracellular parasites that have been labelled so they are visible.
032
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 14/04/2026
By bringing together expertise from DDU, @uofwa.uw.edu, & @dndi.org, we’re working to turn scientific potential into real progress against #ChagasDisease. Tackling #neglecteddiseases takes more than innovation—it takes #collaboration. #DrugDiscovery #GlobalHealth #WorldChagasday
One conversation. One shared goal.
 
From a conference in Bolivia to a global collaboration, teams at DDU, the University of Washington, and DNDi are working together to develop new treatments for Chagas disease.
042
Reposted by Drug Discovery Unit, University of Dundee
Scottish Funding Council @scotfundcouncil.bsky.social · 14/04/2026
World Chagas Disease Day acts as a reminder of a global health challenge that often goes unnoticed. In our latest blog, Manu De Rycker from the @dundee.ac.uk shares what his team are doing to combat this disease. #ChagasDisease www.sfc.ac.uk/inside-the-u...
sfc.ac.uk
Inside the University of Dundee’s long‑term fight against Chagas disease - Scottish Funding Council
World Chagas Disease Day acts as a reminder of a global health challenge that often goes unnoticed. Manu De Rycker shares what his team are doing to combat this disease.
065
Reposted by Drug Discovery Unit, University of Dundee
Immunopaedia @immunopaedia.bsky.social · 14/04/2026
Observed on April 14, World Chagas Disease Day shines a light on a often “silent” but impactful neglected tropical disease: Chagas disease. Today is a reminder of the importance of addressing neglected diseases and support affected communities. #WorldChagasDiseaseDay #ChagasDisease
001
Reposted by Drug Discovery Unit, University of Dundee
Unitaid @unitaid.bsky.social · 14/04/2026
On World Chagas Disease Day, Unitaid highlights the importance of screening for Chagas disease. Too often, people are diagnosed late or not at all. Through SafeStart+, we are integrating screening into antenatal care. Learn more: ow.ly/9Tsa50YI5lH
ow.ly
Eliminating vertical transmission of HIV, hepatitis B, syphilis, and Chagas disease - Unitaid
021
Reposted by Drug Discovery Unit, University of Dundee
WHO @who.int · 14/04/2026
Today is World #ChagasDisease Day. For too long, women have been stigmatized for a disease they didn't choose. Most were infected the same way as everyone else by insect transmission, contaminated food, or other routes. It's time to replace stigma with support. 🧡 Learn more 👉 bit.ly/4cIYv4I
Graphic showing a seated woman with her head down, alongside text reading: “For too long, women have been blamed as a source of Chagas disease.” An icon of the insect vector appears beside her. A red banner at the bottom reads: “It’s time to shift the story.”
06021
Reposted by Drug Discovery Unit, University of Dundee
Journal of Experimental Biology @jexpbiol.bsky.social · 07/04/2026
We are calling for Reviews, Commentaries or research papers for our upcoming Special Issue: The Integrative Biology of Reproduction, covering the entire reproductive process, from mate selection, mating and egg-laying or pregnancy through to parental care bit.ly/3ZT42hY
A card announcing the call for papers stating 'Special Issue: The Integrative Biology of Reproduction Guest Editors: Etya Amsalem, Tony D. Williams and Kathryn Wilsterman. Submission deadline: 30 June 2026' with the Journal of Experimental Biology logo and the logo for the Special Issue containing an egg cell surrounded by eight sperm cells. The eighth sperm, on the top right, is penetrating the egg.
055
Reposted by Drug Discovery Unit, University of Dundee
Derek Lowe @dereklowe.bsky.social · 16/03/2026
Some good news: the most effective drug ever found against sleeping sickness (curative in one oral dose!) is being rolled out:
science.org
The Best Weapon Yet Against Sleeping Sickness
07521
Reposted by Drug Discovery Unit, University of Dundee
UK Research and Innovation @ukri.org · 17/03/2026
We're hosting a virtual town hall on 24 Mar, 3-4pm, where our CEO, Professor Sir Ian Chapman, will outline UKRI's upcoming five-year strategy & new mission. He'll be joined by an executive panel and a Q&A will follow. Registration closes 23 Mar, 5pm. Register here⬇️
forms.office.com
Microsoft Forms
0919
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 30/01/2026
Want to see what we do up close? Sign up for the tour and networking event with us and #biodundee. See the link for details and tickets! #DDUat20 www.eventbrite.co.uk/e/drug-disco...
eventbrite.co.uk
Drug Discovery Unit Tour and Networking
BioDundee is delighted to kick of the year of celebrations for #DDUat20 with Networking and a guided tour of the Drug Discovery Unit.
023
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 30/01/2026
Today is World Neglected Tropical Diseases Day. The Neglected Tropical Diseases (NTDs) are a group of diseases that affect >1 billion people worldwide (~1 in 8 people). Despite this number, treatments and diagnostics are often unsafe and unsuitable, if they even exist. www.who.int/health-topic...
who.int
Neglected tropical diseases -- GLOBAL
Neglected tropical diseases (NTDs) are a diverse group of 20 conditions that are mainly prevalent in tropical areas, where they mostly affect impoverished communities and disproportionately affect wo...
132
Reposted by Drug Discovery Unit, University of Dundee
Maggie Chapman (she/her) @maggiechapman.bsky.social · 30/01/2026
🤝 Catering partner sought for Dundee pilot: Nourish Scotland is looking for an experienced hospitality business or organisation for #PublicDiner trial. 🗣️ The project offers a subsidy of £240,000 to local businesses and organisations, plus research and partnership support. 1/2
144
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 27/01/2026
As part of our #20thBirthday celebrations, we hear from our cofounders Sir Mike Ferguson and Alan Fairlamb #ScienceNeverStops www.youtube.com/watch?v=_Skb...
youtube.com
DDU at 20 | Founders Sir Michael Ferguson & Alan Fairlamb on Past, Present and Future
YouTube video by Drug Discovery Unit Dundee
041
Reposted by Drug Discovery Unit, University of Dundee
Sam Hobbs @hobbslabutah.bsky.social · 22/01/2026
Hello world! I am excited to announce my lab is open at the University of Utah in the Department of Biochemistry. We are looking for scientists at all levels interested in studying host-virus interactions in both bacteria and animals. Come join us in beautiful Utah! (photo is 10 steps from lab)
67531
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 23/01/2026
It's our Birthday!!
044
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 31/10/2025
Science is pretty! Seems like a great time to find out about the incredible impact that #HenriettaLacks had on modern science!
030
Reposted by Drug Discovery Unit, University of Dundee
Manu De Rycker @mdr-ddu.bsky.social · 31/10/2025
Hot off the press: our Target Product Profile to support the development of new medicines to treat #cryptococcal disease: www.sciencedirect.com/science/arti... #cryptococcus, #drugdiscovery, #meningitis @ddu-dundee.bsky.social, @gsk.bsky.social, @dndi.org and many others 🧪
sciencedirect.com
Target product profile and discovery and development path for novel cryptococcal disease treatments
Cryptococcus neoformans and Cryptococcus gattii are World Health Organization critical and medium priority pathogens, respectively. These mainly impac…
064
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 23/10/2025
Good morning sky-friends! We have exciting news today! Our head of biology Dr @mdr-ddu.bsky.social has been awarded the WH Pierce Global Impact in Microbiology Prize by @amiposts.bsky.social as part of their International Horizon Awards drugdiscovery.dundee.ac.uk/news/dr-manu...
drugdiscovery.dundee.ac.uk
Drug Discovery Unit - Dr Manu De Rycker recognised with global honour
Dr Manu De Rycker has been named as the newest winner of the WH Pierce Global Impact in Microbiology Prize.
042
Reposted by Drug Discovery Unit, University of Dundee
Manu De Rycker @mdr-ddu.bsky.social · 16/09/2025
#Chagas disease remains very neglected, and not only in the US, in spite of an estimated 8 million people being infected with T. cruzi. We, and our collaborators, aim to develop new medicines, but this is becoming increasingly challenging due to lack of funding. www.theguardian.com/us-news/2025...
theguardian.com
‘Kissing bug’ disease should be treated as endemic in US, scientists say
People in at least eight states have been infected with Chagas, new report says, amid low awareness of disease
123
Reposted by Drug Discovery Unit, University of Dundee
UNLEASH @unleash-as.bsky.social · 17/09/2025
Good morning Bluesky! We have reached the end of our UNLEASH meeting and are all preparing to head home. We are full of enthusiasm and renewed purpose, and we look forward to keeping you all updated on our work! Tell us - what do you want to know about us? #SciComm #RNA #Splicing
032
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 16/09/2025
Good morning Sky-Friends! Our own @biochemtrix.bsky.social (and occasional poster!) is in Germany at the #Unleash consortium meeting. They are joining us here in the sky @unleash-as.bsky.social so follow along to find out about #AlternativeSplicing!
160
Reposted by Drug Discovery Unit, University of Dundee
Manu De Rycker @mdr-ddu.bsky.social · 27/08/2025
Great opportunity to join our multi-partner collaboration to develop much needed new #antifungal drugs! #jobs, #drugdiscovery, #Cryptococcus, #Candida @mrccmm.bsky.social @ddu-dundee.bsky.social @labwyllie.bsky.social @glaxosmithkline.bsky.social
032