And it's not all: For an exceptional new product, an exceptional new casing!
We designed new boxes that we will gradually deploy to replace our old metal boxes. 4 designs will be randomly used for each product!
Spirochrome
@spirochrome.com
2.3K followers 4.1K following 115 posts
Our main focus is to offer innovative tools for live cell fluorescence imaging to the scientific community. spirochrome.com
![Live-cell confocal imaging of histone H2B type-2E-Hpep11 CRISPR KI cell lines after 2-hours labeling with the specified CA- ligand [100 nM]. Images were taken with optimal image acquisition parameter for each dye. Scale bar: 50 μm.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:uf4m7zlmcjlg2biwn4s2k32y/bafkreibozn5fz6sgeksqrz3vmy6uiydtnvwmb5my7r3xecko2erokryn3a)
![(a) Confocal laser scanning microscopy (CLSM) and STED images of mitochondria in U2OS cells coexpressing cpHaloΔ3 and TOM20-Hpep, either overexpressed or endogenously tagged. Scale bar: 1 μm. Pixel intensities scaled according to reference bar. (b) Representative CLSM, STED images of the CRISPR/Cas9 KI cells expressing TOM20 tagged with intact HaloTag (upper) or Hpep11 (bottom). (c) Intensity profiles along mitochondrial tubules (red and blue lines in b). Scale bar: 2 μm. (d) Representative CLSM and STED images of endogenous Hpep11-tagged clathrin with cpHaloΔ3 coexpression. Scale bar: 10 μm (overview) and 2 μm (magnification). (e) Representative CLSM, STED
images of endogenously tagged tubulin beta 4B with Hpep11. Scale bar: 10 μm (overview) and 2 μm (magnification). (f) Intensity profiles along tubulin filaments (red and blue lines in e) Means ± s.d. of the filament diameters were calculated as full width at half maximum (FWHM) from n=20 microtubule filaments, ≥ 2 images. A slight increase in cytosolic signal was noted in cells tagged with split-HaloTagat TUBB4B, compared to cells tagged with the full-length HaloTag, which may result from the presence of unbound but labeled cpHaloΔ3. All images were acquired after labeling with CA-SiR [100 nM] for one hour.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:uf4m7zlmcjlg2biwn4s2k32y/bafkreielty6fex37xy4caechbw5ebo3eypyiyvxxhkigeazd5gmy6tvlay)
