ALT: The Mandalorian: This Is The Way

Protein language models have excelled at modeling individual proteins, but extending these capabilities to protein complexes remains a major challenge. MSA Pairformer, a parameter-efficient protein la...

Age of Epochs II. Contribute to sokrypton/aoe development by creating an account on GitHub.

AlphaFold 3 inference pipeline. Contribute to sokrypton/alphafold3 development by creating an account on GitHub.

Because all known living organisms are made from at least 20 canonical amino acids, the feasibility of life using a more simplified alphabet remains unclear. In this work, we leveraged computational d...

Nature Methods - AF2BIND is a logistic regression model trained on AlphaFold2 pair features to predict small-molecule binding-site residues in proteins, without multiple sequence alignments,...

Protein structure-based homology detection has been revolutionized by deep learning methods that can rapidly search massive databases. However, current structural search tools often miss proteins rela...

Protein-protein interactions (PPIs) drive virtually all biological processes, yet most PPIs have not been identified and even more remain structurally unresolved. We developed a two-step computational...