iiinova — where your digital self keeps evolving

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Rhein-Main-Universitäten @rheinmainunis.bsky.social · 02/10/2026

🎉 WIR HABEN ES GESCHAFFT: Die Allianz der #RheinMainUniversitäten (RMU) aus @goetheuni.bsky.social, @unimainz.bsky.social & @tuda.bsky.social wird ab 2027 im Rahmen der #Exzellenzstrategie als #Exzellenzverbund gefördert: www.rhein-main-universitaeten.de/news/rhein-m... @dfg.de @wissenschaftsrat.de

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Goethe-Universität Frankfurt @goetheuni.bsky.social · 25/09/2026

Weil’s so schön war: Noch ein kleiner Videorückblick aufs #ScienceFestival! 🎬 Vor knapp einer Woche gab’s auf dem Roßmarkt Wissenschaft zum Anfassen und Entdecken. Danke an alle, die mitgemacht, gefragt, gestaunt und erklärt haben! 🔬 #Frankfurt #FrankfurtAlliance

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Gabrijela Dumbović @gabrijelad.bsky.social · 09/09/2026

⏳ Intron retention spans distinct lifetimes. While many retained introns were resolved rapidly, a substantial population persisted for hours. These long-lived retained introns were enriched in transcripts encoding regulators of mitosis, cell cycle, DNA repair and genome maintenance.

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Heilemann Lab @heilemannlab.bsky.social · 15/09/2026

👉🏻 this project was driven — enthusiastically and excellently — by Olivia Jacobs (Robert Tampé group) and Tanja Menche @heilemannlab.bsky.social, and in collaboration with TRON Mainz. @goetheuni.bsky.social @scale-cluster-ffm.bsky.social @crc1507.bsky.social #DNAPAINT #superresolution #MHC

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SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · 09/07/2026

🤖🦠We're looking for computational scientists, AI engineers, biomolecular modelers, image-analysis researchers, HPC engineers, data stewards, and visualization developers to help build the first Digital Twins of subcellular architecture! 🤝 Combine expertise is welcomed!

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SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · 09/07/2026

🚀 We're hiring! Join the founding Digital Twin Team at the SCALE Cluster of Excellence @goetheuni.bsky.social Apply by: 31 August 2026 For more information: scale-frankfurt.org/wp-content/u... Full position description: scale-frankfurt.org/wp-content/u... Descriptions below 🧵:

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Kurianlab @kurianlab.bsky.social · 19/06/2026

Seminar Alert *Lineage Tracing and Disease modeling in human embryos* Rio Sugimara, Hong Kong University When: 26. 06. 2026, 15:00 Where: H22-2, Medical faculty, Goethe University Frankfurt @riosugimura.bsky.social @cpi-exstra.bsky.social @goetheuni.bsky.social @scale-cluster-ffm.bsky.social

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Max Planck Institute of Biophysics @mpibp.bsky.social · 26/06/2026

1/3: We are excited to share a new study by Maarten Tuijtel from @becklab.bsky.social, published in eLife. 🔬 🎉 The work addresses a key question in cryo-electron tomography: how to best distribute the limited electron dose across a tilt series while balancing angular sampling and image quality. 💥

Cryo-EM images showing sample structures at tilt increments from 1 to 10 degrees, with resolution patterns and measured values in nanometers.

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Michaela Müller-McNicoll @mixmue.bsky.social · 17/06/2026

How can a splicing factor bind to thousands of exons but regulate only a few of them? In our new preprint, we show that SRSF6 resolves this paradox through two distinct binding modes. @lab-nmr.bsky.social & @julianvonehr.bsky.social. Check it out: www.researchsquare.com/article/rs-9...

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Max-Planck-Gesellschaft @maxplanck.de · 10/06/2026

Congratulations, Erin Schuman! The director at the Max Planck Institute for Brain Research receives the #KavliPrize 2026 in the field of #neuroscience 🎉 @kavlifoundation.org @mpibrain.bsky.social

Erin Schuman investigates the cellular mechanisms and neural circuits that underpin information processing and storage in the brain. Her laboratory focuses on the molecular and cellular processes that govern protein synthesis and degradation in nerve cells and their synapses.

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Kurianlab @kurianlab.bsky.social · 28/05/2026

Seminar Alert: *Prof. Elena Conti* 'RNA exosome complex: Molecular Mechanisms of RNA degradation in health and disease' When: 18.06.2026, 14:00 Where: Haus 22-1 (lecture hall H22-1), Neiderad Campus (Uni KliniK), Goethe University RT🙏 @scale-cluster-ffm.bsky.social @goetheuni.bsky.social

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Gabrijela Dumbović @gabrijelad.bsky.social · 22/05/2026

Our lab is expanding! We are looking for a PhD candidate interested in RNA localization & targeting as part of the newly funded TRR440 smART: specific mRNA targeting. An exciting opportunity to work on RNA biology & innovative approaches in a collaborative environment. For details shorturl.at/RjyhE

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SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · 13/05/2026

Congratulations to all authors! 👏 Pos Lab: www.theposlab.de Frangakis Lab: frangakis.biophysik.org

theposlab.de

PosLab

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SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · 13/05/2026

Using cryo-EM, X-ray crystallography, simulations, and functional assays, the team shows how BDM91531 blocks the pump’s conformational cycling, offering a blueprint for designing next-generation efflux pump inhibitors.

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SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · 13/05/2026

In a new collaborative study, SCALE researchers and partners from France and Italy uncover how BDM91531, a high-affinity inhibitor, targets the AcrAB–TolC efflux pump in bacteria such as E. coli and Klebsiella pneumoniae.

lnkd.in

This link will take you to a page that’s not on LinkedIn

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Goethe-Universität Frankfurt @goetheuni.bsky.social · 15/04/2026

Der neue UniReport 1/2026 ist da 📰 Unter anderem mit dem Auftakt des Exzellenzclusters @scale-cluster-ffm.bsky.social, Poetikvorlesungen, Nachrufen auf Jürgen Habermas und einer Story mit vier Wegen aus dem Ukraine-Krieg. 👉 Jetzt lesen: www.unireport.info/aktuelle-aus....

Hand hält eine Ausgabe der Zeitung „UniReport“ (Nr. 1.26) vor einem unscharfen Hintergrund mit Bäumen, Weg und blauem Himmel mit Wolken; auf der Titelseite ist eine farbige Illustration sowie mehrere Artikelankündigungen sichtbar.

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Heilemann Lab @heilemannlab.bsky.social · 04/02/2026

🔬we have been playing with 'an old tool from (DNA) chemistry' 🧪 and used that for DNA-based confocal/super-res microscopy ... these are the last recordings for the revision and were recorded last night ... 🙏 thanks to R1 for this suggestion:

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Goethe-Universität Frankfurt @goetheuni.bsky.social · 16/01/2026

Goethe University now has a state-of-the-art scanning electron microscope with nanomanipulator 🤩. It enables precise nanobiopsies of biological samples and is a key technology for the Cluster of Excellence @scale-cluster-ffm.bsky.social. 🔗 Read more: aktuelles.uni-frankfurt.de/english/a-vi...

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IMPRS on Cellular Biophysics @imprs-cbp.bsky.social · 14/01/2026

🌟 PhD positions at IMPRS-CBP! Applications open from Jan 23 – Mar 11. Fully funded PhDs in cellular biophysics at @mpibp.bsky.social , @goetheuni.bsky.social l and @unimainz.bsky.social . 👉 imprs-cbp.mpg.de #phd #biophysics #imprs_cbp

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Goethe-Universität Frankfurt @goetheuni.bsky.social · 12/01/2026

🧪 Forschende der Goethe-Uni haben das Enzym Fettsäuresynthase neu programmiert, um nachhaltige Fettsäuren ohne #Palmöl zu produzieren. Durch gezielte Veränderungen können nun kürzere Kettenlängen hergestellt werden. 🔗 Mehr: aktuelles.uni-frankfurt.de/forschung/de... @scale-cluster-ffm.bsky.social

Foto einer Palmölplantage. Darauf der Text "Designer-Enzyme statt Palmöl. Forschende der Goethe-Universität Frankfurt haben einen innovativen Ansatz entwickelt, um Fettsäuren nachhaltig zu produzieren."

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Goethe-Universität Frankfurt @goetheuni.bsky.social · 12/01/2026

🧪 Researchers at Goethe University have reprogrammed the enzyme fatty acid synthase to produce sustainable fatty acids without #palm#oil. Through targeted modifications, shorter chain lengths can now be produced. 🔗 More: aktuelles.uni-frankfurt.de/english/from... @scale-cluster-ffm.bsky.social

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SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · 12/01/2026

🚀 Giersch International Conference & SCALE Kick-Off on Digital Twins is coming up! 🗓️ March 2–5, 2026 | 📍 Frankfurt Main Experts in digital twins & structural cell biology come together to discuss, challenges & future directions in biology.

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SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · 19/12/2025

Application deadline: 18 January 2026 For details and application instructions, visit: berufungsportal.uni-frankfurt.de Further information about SCALE can be found at: scale-frankfurt.org @mpibp.bsky.social @mpibrain.bsky.social @proloewe.bsky.social @unimainz.bsky.social @FIAS

berufungsportal.uni-frankfurt.de

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SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · 19/12/2025

⏰Call for Applications - Join Our Team and Help Shape Our Cluster @goetheuni.bsky.social and the Cluster of Excellence SCALE - Subcellular Architecture of Life are seeking 3 highly motivated scientists to join a vibrant and innovative research community on Campus Riedberg. Share with your network!

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Max Planck Institute of Biophysics @mpibp.bsky.social · 17/12/2025

Vault particles, a 40-year cell biology mystery, associate with membranes at the nuclear envelope and ER—revealing a new functional axis for these conserved complexes @kgeissler.bsky.social @yuningwang.bsky.social @jpkreysing.bsky.social @Becklab.bsky.social: www.biorxiv.org/content/10.6...

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Melanie McDowell @melaniemcdowell.bsky.social · 16/12/2025

The last chapter from my postdoc days is finally online! We solve structures of the ER membrane O-mannosyltransferase Pmt4 and uncover a functionally important cytosolic binding site for the Dol-P-Man substrate lipid - allosteric regulation or a long sought after Dol-P-Man flippase?? 🔄 rdcu.be/eUJfb

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Ben Barad @baradlab.com · 12/12/2025

Holy cow the Zhou lab at UCLA is cooking with Isonet 2 - www.biorxiv.org/content/10.6... Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet

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Miao Yu @miao-yu.bsky.social · 13/12/2025

How liquid-like is the nuclear pore barrier?🍝𖣐 Our new preprint shows that FG-NUPs exhibit nanosecond-scale, liquid-like mobility in living cells. 💧⚡O-GlcNAcylation and an importin-β gradient keep the FG network liquid-like, reconciling nuclear pore complex models.

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Kurianlab @kurianlab.bsky.social · 11/12/2025

Before you decorate the tree, come decorate your RNA next Thursday, 4 pm, 18.12.2025 Our last RNA event before the holidays. Also:Glühwein&snacks Registration: rmu-rna-salon.idloom.events/2-rmu-rna-sa... Please share @mixmue.bsky.social @cpi-exstra.bsky.social @scale-cluster-ffm.bsky.social

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Michaela Müller-McNicoll @mixmue.bsky.social · 28/11/2025

It’s out 🥳🥳. Amazing new insights into Paraspeckles by SMART 3D STED imaging. Paraspeckles can be polar and fuse and have an interesting loop that contacts the nucleoplasm. Kudos to @heilemannlab.bsky.social, Sjoerd Stallinga and Bernd Rieger.

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Heilemann Lab @heilemannlab.bsky.social · 28/11/2025

Exceptional work by Enya (TU Delft) and Laurell (Frankfurt) 💪 and a great team 👍 & great support by our Exc Cluster @scale-cluster-ffm.bsky.social @goetheuni.bsky.social & we thank our Editor and the Reviewers for their valuable input @natcomms.nature.com #FluorescenceFriday #smartmicroscopy #RNA

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Heilemann Lab @heilemannlab.bsky.social · 28/11/2025

We developed a 'smart STED microscope' to detect rare objects/events in cells, and unraveled the 3D morphology of a nuclear membraneless organelle (paraspeckle). Amazing collaboration with Sjoerd Stallinga, Bernd Rieger (TU Delft) and @mixmue.bsky.social 🙏 (1/3) www.nature.com/articles/s41...

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Heilemann Lab @heilemannlab.bsky.social · 20/11/2025

🚨🔬A great opportunity to work with high-end microscopy in an exciting scientific environment. Please re-post 🙏 @goetheuni.bsky.social @scale-cluster-ffm.bsky.social 👇🏻

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Yvonne Stahl @yvonnestahl.bsky.social · 19/11/2025

A great opportunity to join our newly established imaging centre in Frankfurt as engineer/technician. If you love light microscopy, please apply! Please share!

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Rhein-Main-Universitäten @rheinmainunis.bsky.social · 12/11/2025

💥"RMU-EXCITE": Die Allianz der Rhein-Main-Universitäten (RMU) @goetheuni.bsky.social, @unimainz.bsky.social und @tuda.bsky.social hat ihren gemeinsamen Antrag als #Exzellenzverbund (Förderlinie Exzellenzuniversitäten) eingereicht! Pressemitteilung: www.rhein-main-universitaeten.de/news/rhein-m...

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SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · 14/11/2025

📢 We’re hiring an Office and Financial Coordinator to support our team’s administrative operations. Learn more and apply here 👉

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Goethe-Universität Frankfurt @goetheuni.bsky.social · 12/11/2025

🚀 #Karriere im Blick? #Mentoring Hessen unterstützt #Frauen auf ihrem Weg in Wissenschaft & Wirtschaft – mit vier Mentoring-Programmen für Studentinnen bis hin zu angehenden Professorinnen. Jetzt bis 1. Dezember (15. Dez. für ProProfessur) bewerben 👉 www.mentoringhessen.de/jetzt-bewerb...

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Murphy Lab @bjmurphylab.bsky.social · 05/11/2025

Exciting week in Frankfurt! Our CEOS energy filter and ASI Timepix3 are installed and we're looking forward to running the first tests :) #CryoEM #timepix #REELanalysis #4DSTEM @mpibp.bsky.social

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Journal of Cell Biology @jcb.org · 04/11/2025

Glushkova, Böhm, & Beck @maxplanck.de develop a publicly available computational method to measure the thickness of biological membranes in cryo-electron tomograms. Analysis of algae & human cells reveals systematic membrane thickness variations within & across organelles rupress.org/jcb/article/...

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Desislava Glushkova @deglushk.bsky.social · 06/11/2025

Just published! We share an open-source workflow to measure membrane thickness from tomograms, including a tutorial with 3D visualizations. We analyze thickness variations across organelles and reflect on where to define a membrane boundary. @becklab.bsky.social #teamtomo rupress.org/jcb/article/...

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Max Planck Institute of Biophysics @mpibp.bsky.social · 30/10/2025

SNDing proteins into the membrane! Our new publication from @melaniemcdowell.bsky.social ’s group identifies the SND3 protein as a new route for membrane protein insertion! 🍄 📘 Read more here: www.mpg.de/25599408/102... Image: Louise Duever.

Structure of the ribosome-bound SND3 translocon complex from the heat-tolerant fungus Chaetomium thermophilum. The SND3 translocon inserts proteins into the endoplasmic reticulum membrane as they are produced by the ribosome.

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Goethe-Universität Frankfurt @goetheuni.bsky.social · 27/10/2025

🧬 Der Paul Ehrlich- und Ludwig Darmstaedter-Preis 2026 geht an Davor Solter & Azim Surani – sie entdeckten, dass wir für ein gesundes Leben die Gene beider Eltern brauchen. Ihre Arbeit zur genomischen Prägung öffnete das Tor zur modernen Epigenetik. | tinygu.de/PELD-Preis-2...

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