iiinova — where your digital self keeps evolving

Reposted by Yuning Wang

Katharina Geißler @kgeissler.bsky.social · 21/04/2026

Out now in Nature Communications! We show that Dictyostelium vaults associate with ER and NE membranes in situ and encapsulate ribosomes with defined orientations, shining new light on their cellular function! #TeamTomo #TeamMassSpec #ProtistsOnSky www.nature.com/articles/s41...

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Reposted by Yuning Wang

Katharina Geißler @kgeissler.bsky.social · 16/12/2025

It’s out! Using cryo-ET in Dicty cells, we take a fresh in situ look at vaults. Surprisingly, we uncover vaults associated with ER and NE membranes, and find that many vaults enclose ribosomes in defined orientations, opening new avenues to their cellular function! www.biorxiv.org/lookup/conte...

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Reposted by Yuning Wang

Desislava Glushkova @deglushk.bsky.social · 06/11/2025

Just published! We share an open-source workflow to measure membrane thickness from tomograms, including a tutorial with 3D visualizations. We analyze thickness variations across organelles and reflect on where to define a membrane boundary. @becklab.bsky.social #teamtomo rupress.org/jcb/article/...

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Reposted by Yuning Wang

Max Planck Institute of Biophysics @mpibp.bsky.social · 10/10/2025

Fantastic new work from our researchers! Check out their work on 🐯 cryoTIGER for cryoET 🐯

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Reposted by Yuning Wang

Jan Philipp Kreysing @jpkreysing.bsky.social · 23/07/2025

New from my colleagues Markus Schreiber & Beata Turoňová: TANGO, an #opensource tool for more holistic spatial analysis of cryo-ET particles. It can clean or cluster particles, analyze lattices, and identify patterns. #TeamTomo www.biorxiv.org/content/10.1...

biorxiv.org

Twist and Scout: Analysis and Curation of Particles in Cryo-Electron Tomography Using TANGO

Cryo-electron tomography (cryo-ET) enables the visualization of cellular structures in near-native environments, but its potential for spatial analysis has been underutilized due to a lack of versatil...

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Reposted by Yuning Wang

Uri Manor @manorlaboratory.bsky.social · 02/07/2025

Excited and honored to speak at the @royalmicrosoc.bsky.social meeting tomorrow where I'll talk about our latest AI tools. Meanwhile, check out Vijay&Arlo's Napari "bootstrapper" plugin for massively accelerated segmentation of multidimensional imaging datasets Github: github.com/ucsdmanorlab...

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Reposted by Yuning Wang

bioRxivpreprint @biorxivpreprint.bsky.social · 14/03/2025

In situ evidence for systematic membrane thickness variation across cellular organelles www.biorxiv.org/content/10.1101/202…

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Reposted by Yuning Wang

bioRxivpreprint @biorxivpreprint.bsky.social · 15/03/2025

Automated Removal of Corrupted Tilts in Cryo-Electron Tomography www.biorxiv.org/content/10.1101/202…

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