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Shawn Baker

@sandiegomics.bsky.social
890 followers 185 following 92 posts

Genomics consultant/advisor/investor sandiegomics.com

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Reposted by Shawn Baker
Jonathan Wosen @jonathanwosen.bsky.social · 24/02/2026
Jeffrey Epstein’s tissue samples ignited a furor in the Harvard lab of George Church, reports @mmolteni.bsky.social in this @statnews.com exclusive. 13 years later, the whereabouts of the sex offender’s skin cells are a mystery www.statnews.com/2026/02/24/e...
statnews.com
Jeffrey Epstein’s tissue samples ignited a furor in the Harvard lab of George Church
Exclusive: Harvard geneticist George Church knew more about Jeffrey Epstein's activities than he has previously said, before accepting new donations from the sex offender.
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Shawn Baker @sandiegomics.bsky.social · 24/02/2026
Illumina officially launches TruPath, their pseudo-long read sequencing kit (formerly called Constellation), at #AGBT #AGBT25 www.illumina.com/company/news...
illumina.com
Illumina launches TruPath Genome, setting a new standard in genomic insight
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Shawn Baker @sandiegomics.bsky.social · 19/02/2026
I have a little more detail and some commentary here - sandiegomics.com/element-join...
sandiegomics.com
Element Joins the High-Throughput Market with the VITARI Platform
Back at JPM Element teased that they would be coming out with the VITARI, a benchtop sequencer capable of generating whole genomes for $100. This would best Illumina’s list price of $200 with the N…
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Shawn Baker @sandiegomics.bsky.social · 19/02/2026
Element reveals more information about their VITARI platform, a foray into the high-throughput sequencing market. sandiegomics.com/element-join...
sandiegomics.com
Element Joins the High-Throughput Market with the VITARI Platform
Back at JPM Element teased that they would be coming out with the VITARI, a benchtop sequencer capable of generating whole genomes for $100. This would best Illumina’s list price of $200 with the N…
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Shawn Baker @sandiegomics.bsky.social · 02/02/2026
PacBio’s very expensive foray into short read sequencing is now officially over. 🙄 www.pacb.com/press_releas...
pacb.com
PacBio Completes Sale of Short-Read Sequencing Assets - PacBio
MENLO PARK, Calif., Feb. 02, 2026 (GLOBE NEWSWIRE) — PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, today announced the completion of the sale of sel...
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Reposted by Shawn Baker
Keith Robison @omicsomics.bsky.social · 02/02/2026
Non-coding DNA's Alpha Moment 🧬🖥️ omicsomics.blogspot.com/2026/02/non-...
omicsomics.blogspot.com
Non-coding DNA's Alpha Moment
I had been meaning to read the AlphaGenome paper on non-coding variant effect prediction from Google DeepMind which recently showed up in N...
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Reposted by Shawn Baker
Kevin Davies @kevinadavies.bsky.social · 10/11/2025
Some close encounters with Jim Watson: www.genengnews.com/topics/omics...
genengnews.com
DNA and the Unraveling of James Watson
A personal reflection on the life, legacy, and controversies of DNA co-discoverer James Watson, following his death at age 97.
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Shawn Baker @sandiegomics.bsky.social · 07/08/2025
Some consolidation in the single cell space - 10X Genomics (@10xgenomics.bsky.social) set to acquire Scale Biosciences www.genengnews.com/topics/omics...
genengnews.com
10x Genomics Scales Up, Agrees to Acquire Scale Biosciences
An exclusive interview with Serge Saxonov of 10x Genomics and Giovanna Prout of Scale Biosciences on what the acquisition means for single cell genomics.
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Reposted by Shawn Baker
Element Biosciences @elembio.bsky.social · 29/07/2025
📢 We are very proud to announce that over 50 of our #AVITI24 5D #multiomic systems have already been installed around the globe enabling scientists to unravel the most complex questions about our biology. bit.ly/458UCky
bit.ly
Element Biosciences Surpasses 50 AVITI24™ 5D Multiomic System Installations In Just Months
Element Biosciences today announced that installations of its flagship AVITI24 5D Multiomic system have surpassed 50 units globally.
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Shawn Baker @sandiegomics.bsky.social · 03/07/2025
Atlas, Twist's DNA data storage spin-off, is claiming that "pretty quickly" the majority of DNA sequencing (by "orders of magnitude") will be for reading data storage. I'm skeptical. Maybe we have different definitions of "pretty quickly". #dnasynth #datastorage www.genomeweb.com/business-new...
genomeweb.com
Twist Spinoff Atlas Data Storage Designing Chip, Seeking Partner for Sequencing DNA-Based Archives
The California startup will have to convince companies across the economy to swap from rolls of magnetic tape to DNA as the vessel for their most important digital data.
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Reposted by Shawn Baker
Kristian G. Andersen @kgandersen.bsky.social · 26/06/2025
Quick update on this - a good one! Thanks to our fantastic colleagues at county HHSA, we're able to continue our wastewater surveillance work, including generating retroactive data from the last few months, as well as new data moving forward. For how long, we'll see, but expect updates soon! 🌟❤️
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Reposted by Shawn Baker
Vincent J Lynch 🐘🦣🦥 🦇🐋🐢🐍 @devoevomed.bsky.social · 12/06/2025
Updated a broken link in my substack post about the #ColossalBio #DeExtinction #DisInformation campaign – dire wolves are still extinct. open.substack.com/pub/devoevom...
open.substack.com
The Extinction of Truth
Or, a Colossal Pile of Bullshit
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Shawn Baker @sandiegomics.bsky.social · 23/06/2025
Illumina goes “all in” on proteomics by purchasing SomaLogic (from Standard BioTools). Can they overtake Olink? www.illumina.com/company/news...
illumina.com
Illumina to acquire SomaLogic, accelerating its proteomics business and advancing the company's multiomics strategy
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Shawn Baker @sandiegomics.bsky.social · 17/06/2025
Can't wait to listen to this one!
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Shawn Baker @sandiegomics.bsky.social · 17/06/2025
www.genengnews.com/topics/artif...
genengnews.com
Xaira Therapeutics Releases Largest Perturb-Seq Dataset to Power the Virtual Cell
The AI unicorn's Perturb-seq atlas is publicly available and detects dose-dependent genetic effects to enhance predictive power for drug discovery.
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Shawn Baker @sandiegomics.bsky.social · 11/06/2025
The most charitable thing I can say about Twist’s (@twistbioscience.com) China tariff request is that it’s “unconvincing”. Tariffs aren’t the way to protect IP. This is just about making Chinese DNA more expensive. endpoints.news/twist-biosci... downloads.regulations.gov/BIS-2025-002...
downloads.regulations.gov
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Shawn Baker @sandiegomics.bsky.social · 29/05/2025
@jaredwhitlock.bsky.social has written an article about the many new companies spun out/spawned by ex-Illuminites. In it he references the crowdsourced "Illumina Diaspora" database Millard Chan and I created to keep track of them all. sandiegomics.com/illumina-dia... endpts.com/how-illumina...
endpts.com
DNA giant Illumina spawned an ecosystem of competitors and customers
For Illumina, its former employees are both a boon and a problem. In the 27 years since its founding, the DNA sequencing company unlocked new frontiers in biology, medicine and ...
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Shawn Baker @sandiegomics.bsky.social · 29/05/2025
Roche has finally given their upcoming DNA sequencer a name - Axelios. So now we can stop calling it "Genia + Stratos". www.genomeweb.com/molecular-di...
genomeweb.com
Roche Highlights New Tests, Instrument Launches at Investor Day
The firm touted new assays, provided an update on its nanopore sequencer, and offered insights into upcoming pipeline launches.
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Shawn Baker @sandiegomics.bsky.social · 06/05/2025
Illumina hasn't had a lot of wins recently. I think they'd count this as a win. endpts.com/sec-expected...
endpts.com
Exclusive: SEC expected to drop investigation of Illumina's $8B Grail deal
The SEC is expected to drop an investigation into Illumina's $8 billion acquisition of cancer test developer Grail, Endpoints News has learned.
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Shawn Baker @sandiegomics.bsky.social · 06/05/2025
This has to be one of the most "anti-science" and "anti-common sense" administrations the US has ever had. Tariffs are a tax, pure and simple and the consumer will be the one to pay the cost.
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Shawn Baker @sandiegomics.bsky.social · 06/05/2025
@twistbioscience.com is spinning out their DNA data storage tech. Atlas Data Storage is kicking off with $155M in "seed" funding 😳 That's a lot of "seed" for a market that doesn't exist yet. Best of luck! #dnasynthesis investors.twistbioscience.com/news-release...
investors.twistbioscience.com
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Shawn Baker @sandiegomics.bsky.social · 12/04/2025
Novartis announced a big commitment/addition to the San Diego biotech scene. www.sandiegouniontribune.com/2025/04/10/a...
sandiegouniontribune.com
Amid tariff turmoil, Swiss drugmaker commits to build $1.1B research hub in San Diego
Novartis plans to make San Diego the center of its West Coast research hub.
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Shawn Baker @sandiegomics.bsky.social · 04/03/2025
Things just keep getting worse for ILMN. Stagnant growth, increased competition from @elembio.bsky.social and Ultima, the threat of competition from Roche SBX, and now they’re shut down in China where they get 7% of their revenue. Yikes. www.reuters.com/business/hea...
reuters.com
China bans imports of Illumina's gene sequencers right after Trump tariff action
China announced a ban on Tuesday on imports of genetic sequencers from U.S. medical equipment maker Illumina , just minutes after U.S. President Donald Trump's additional 10% tariff on Chinese goods took effect.
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Reposted by Shawn Baker
Eric Topol @erictopol.bsky.social · 01/03/2025
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...
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Shawn Baker @sandiegomics.bsky.social · 28/02/2025
Wow, perhaps Tang Capital was just trying to buy Singular Genomics to shut them down for the cash. I assumed Tang was trying to combine them with other acquisitions. Glad they weren’t the winning bid.
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Reposted by Shawn Baker
Randall Munroe @xkcd.com · 26/02/2025
RNA xkcd.com/3056
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Reposted by Shawn Baker
Catharine.Aquino @catharineaquino.bsky.social · 23/02/2025
Xenium product updates : RNA and protein multiomics workflow @10xgenomics.bsky.social #AGBT2025 #AGBT25
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Reposted by Shawn Baker
Catharine.Aquino @catharineaquino.bsky.social · 23/02/2025
#visiumhd product updates : segmentation , visium HD XL , visium hd 3’ @10xgenomics.bsky.social #agbt25
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Shawn Baker @sandiegomics.bsky.social · 23/02/2025
Looking forward to seeing what 10X has in store for 2025
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Reposted by Shawn Baker
Jared Whitlock @jaredwhitlock.bsky.social · 15/02/2025
I am the features editor at Endpoints News. We're closely reporting on the Trump administration slashing the federal workforce and the impact on biomedical research. I want to hear your stories and tips. Signal at: @jaredwhitlock.73. I can honor requests for anonymity.
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Reposted by Shawn Baker
Jared Whitlock @jaredwhitlock.bsky.social · 20/02/2025
Drug giant Roche has long had a bad reputation in DNA sequencing. But no longer, it appears. Latest here: endpts.com/roche-no-lon...
endpts.com
Roche no longer wants to be where ‘DNA sequencing goes to die’
Has drug giant Roche finally cracked DNA sequencing? The company has claimed it can decode the genome in as little as four hours, potentially a major step forward for an industry that’s vital for diag...
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Shawn Baker @sandiegomics.bsky.social · 20/02/2025
Roche’s Fantasy Sequencer Slowly Turning Into a Fantastic Reality #sequencing #nanopore #genomics sandiegomics.com/roches-fanta...
sandiegomics.com
Roche’s Fantasy Sequencer Slowly Turning Into a Fantastic Reality
After 10+ years of mostly silence, Roche is finally starting to lift the curtain on their nanopore sequencer. It’s based on a combination of Genia’s nanopore platform (acquired in 2014) and Stratos…
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Shawn Baker @sandiegomics.bsky.social · 20/02/2025
I'll post my Roche sequencer update soon (need to wait for the webinar to end), but let's see how ILMN is taking the news...
screen shot of ILMN stock price dropping during the Roche webinar
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Shawn Baker @sandiegomics.bsky.social · 19/02/2025
Maybe a little too much credit to Element and Ultima, but otherwise an excellent story!
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Shawn Baker @sandiegomics.bsky.social · 19/02/2025
#AGBT sounds like it's going to be a banger with lots of big announcements. The latest is Illumina announcing their upcoming high resolution, broad coverage, large surface area spatial transcriptomics platform. Set for launch in 2026. www.genengnews.com/topics/omics...
genengnews.com
Illumina Unveils Spatial Technology Days Before AGBT Meeting
Illumina announces a new NGS-based spatial technology kit and new software platform, Illumina Connected Multiomics.
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Reposted by Shawn Baker
coregenomics.bsky.social @coregenomics.bsky.social · 14/02/2025
Hi everyone on Bluesky working in #genomics #NGS. Today is Valentines day. How many of you are more excited about Feb 20th?! Read my new post on Enseqlopedia Roche emerges from the Lazarus pit to take on Illumina enseqlopedia.com/2025/02/roch...
enseqlopedia.com
Roche emerges from the Lazarus pit
Is Roche going to "knock it out of the park" or "jump the shark"? Everyone I know is excited, even if many of them are sceptical, about the Feb 20th webinar and what we will learn about SBX. Alex Dick...
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Shawn Baker @sandiegomics.bsky.social · 17/02/2025
A sneak peek at Roche’s nanopore sequencer. Really makes me wish I was going to #AGBT this year! #genomics #nanopore #sequencing sandiegomics.com/roche-has-en...
sandiegomics.com
Roche has entered the conversation…
It’s been an exciting couple of years for the sequencing market. Unless you’re a sequencing company, especially one named “Illumina”, and then maybe it’s been more terrifying. But for sequencing cu…
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Reposted by Shawn Baker
Mike Schatz @mikeschatz.bsky.social · 15/01/2025
So long San Diego! Here’s my opinionated meeting report from #PAG2025 | #PAG32. What else did I miss???
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Reposted by Shawn Baker
Ewan Birney @ewanbirney.bsky.social · 03/01/2025
Some thoughts about what I am looking forward this year from my vantage point of computational molecular biology. One mega-trend for me; we will definitely see more AI methods of all sorts emerge.
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Reposted by Shawn Baker
Randall Munroe @xkcd.com · 24/12/2024
What if we put a pool on the moon? Watch the latest What If? video collaboration with Minute Earth! www.youtube.com/watch?v=aIIB...
youtube.com
What if we put a pool on the moon?
YouTube video by xkcd's What If?
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Shawn Baker @sandiegomics.bsky.social · 09/12/2024
Coastal Redwood fairy ring
A ring of coastal redwoods as seen from the center looking up into the canopy with the light shining through.
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Shawn Baker @sandiegomics.bsky.social · 30/11/2024
A gorgeous #sandiego #sunset tonight!
Sunset over the Pacific Ocean with deep red clouds and red reflected on the water
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Reposted by Shawn Baker
Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · 25/11/2024
Look who's here @pnas.org ✔️ @science.org ✔️ @naturecellbiology.bsky.social ✔️ @natrevgenet.bsky.social ✔️ @naturebiotech.bsky.social ✔️ @naturemicrobiol.bsky.social ✔️ @naturechemistry.bsky.social ✔️ @genesdev.bsky.social ✔️ @cellchembiol.bsky.social ✔️ @genomeresearch.bsky.social ✔️ @jcellbiol.bsky.social ✔️
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Keith Robison @omicsomics.bsky.social · 25/11/2024
www.nature.com/articles/s41...
nature.com
A functional microbiome catalogue crowdsourced from North American rivers - Nature
GROWdb defines US river microbiomes at the genome level.
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Reposted by Shawn Baker
Matthew Freeman @mjafreeman.bsky.social · 19/11/2024
Here’s my spreadsheet of starter packs (>80!) related to broadly ‘mechanistic biology’ plus some intriguing extras Complete with collective nouns I’ve been tracking these but now can’t keep up Hope it’s helpful 2/2 docs.google.com/spreadsheets...
docs.google.com
@mjafreeman.bsky.social's BlueSky starter packs for 'mechanistic' biologists
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Jonathan Jacobs @bioinformer.bsky.social · 11/11/2024
During lunch I starting moving my lists over from Twitter to Blue - first one is done: "Genomics Biz" list. It's much smaller here vs. on Twitter as many companies - including ILMN and ONT - don't have a presence on Blue. @pacbio.bsky.social does though! 🙌 Bsky list here: bsky.app/profile/did:...
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Shawn Baker @sandiegomics.bsky.social · 07/11/2024
PacBio’s Vega system - the new (small) thing in long reads sandiegomics.com/pacbios-vega...
sandiegomics.com
PacBio’s Vega system – the new (small) thing in long reads
PacBio has announced their anticipated desktop HiFi sequencer, the Vega sequencing platform, something they’ve been talking about since early 2023. The platform, which is slated to ship in Q1 2025,…
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Shawn Baker @sandiegomics.bsky.social · 29/10/2024
PacBio’s new SPRQ chemistry brings down the LR human genome to $500. Is it enough to move the needle (faster)? sandiegomics.com/pacbio-sprq/
sandiegomics.com
PacBio Brings Down Long Read Human Genome to $500
PacBio announced their new SPRQ long read sequencing chemistry ahead of ASHG. While it improves a couple of things, the headline is that it brings down the cost of a long read HiFi human genome to …
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Shawn Baker @sandiegomics.bsky.social · 28/06/2024
After another year of fresh competition in the DNA sequencing space, there’s a clear loser and clear winner. Surprise twist: it’s the same company! sandiegomics.com/2023-sequenc... #genomics #sequencing
sandiegomics.com
2023 Sequencing Market Share – The Tide is Turning… Very Slowly
It’s an exciting time in the sequencing industry. After years of dominance, Illumina started facing competition on all fronts in 2022. Element Biosciences and Singular Genomics launched their deskt…
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Reposted by Shawn Baker
Keith Robison @omicsomics.bsky.social · 30/04/2024
omicsomics.blogspot.com/2024/04/a-pe...
omicsomics.blogspot.com
A Peek At QuantumSI's Protein Sequencer
A number of academic labs and startups have been trying to build new ways of parallel sequencing of large numbers of peptides using schemes ...
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