Breaking: A federal judge on Monday stalled major parts of health secretary Robert F. Kennedy Jr.’s campaign to remake vaccine policy in the U.S.

An ‘off-the-shelf’ neoantigen vaccine shows safety and immunogenicity in individuals with Lynch syndrome, further advancing hopes for preventive vaccines for hereditary cancer syndromes.

Stanley Plotkin, the 93-year-old "godfather of vaccines," is watching his field’s achievements slip away.

In a phase 2 trial evaluating healthy donor fecal microbial transplantation plus either anti-PD-1 in patients with non-small cell lung cancer or anti-PD-1 and anti-CTLA-4 in patients with melanoma, en...

A series of graphics reveals how the Trump administration has sought historic cuts to science and the research workforce.

In a phase 1b/2 trial, an off-the-shelf vaccine using gorilla adenoviral and modified vaccinia Ankara vectors with over 200 mutated peptides known to be present in persons with mismatch-repair-deficie...

A STAT analysis of vaccine recommendations in 38 countries suggests the U.S. is now an outlier.

The absence of equipoise can turn research into harm

Three studies that leverage blood-based gene expression data identify molecular and cellular host response signatures in sepsis and critical illnesses, opening a pathway to mechanism-anchored precision therapy.

When clinical trials are suddenly halted by US funding cuts, there are repercussions for investigators and patients, and they do not stop at borders.

Malaria remains a major cause of childhood death in sub-Saharan Africa. We leveraged the traditional practice of mothers carrying children on their backs in cloth wraps to assess whether treating t...

My 12-year-old son died from brain cancer. The defunding of the Pediatric Brain Tumor Consortium will deny treatments to children like him.

In the final analysis of a phase 1/phase 2 trial of autologous GD2-targeting CAR T cells in pediatric patients with high-risk metastatic, relapsed or refractory neuroblastoma, treatment was overall we...

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In cohort B of the phase 2 SWOG S1512 trial, pembrolizumab monotherapy in patients with unresectable desmoplastic melanoma elicited a complete response rate of 37% and an objective response rate of 89...

As a vaccine for broad public use, mRNA technology has failed to earn the public’s trust.

In the final analysis of a phase 1 trial evaluating a lymph node-targeting mutant KRAS peptide vaccine combined with CpG in the adjuvant setting for patients with KRAS mutant pancreatic or colorectal ...

Its architect's daughter has cystic fibrosis—and benefits from a "miracle drug" backed by an agency he's attacking.

In justifying the government's termination of $500 million in funding for mRNA vaccine projects, Health and Human Services Secretary Robert F. Kennedy Jr. falsely claimed mRNA vaccines "fail to protec...

Jay Bhattacharya’s tenure as NIH director has seen health disparities research swept up in the Trump administration’s attack on DEI

'They’re not interested in the science': Former NIH nutrition scientist Kevin Hall on how his work with MAHA fell apart.

The National Institutes of Health can’t award grants to outside researchers under a new White House restriction.

Robert F. Kennedy Jr.’s leadership at Health and Human Services has led to changes in vaccine recommendations and access, sparking concerns among medical experts.

Gavi, the vaccine provider for the world’s poorest people, needs an extra US$3 billion to protect infants and other vulnerable groups. More donors must step up.

The Global Neurodegeneration Proteomics Consortium is a multi-national database that aims to leverage proteomics and clinical data to understand and improve ...

The decision means that the US biomedical agency has to restore funding to hundreds of research projects, but the government will likely appeal.

Malaria has found a new ally in the concrete jungle — but scientists are fighting back with mosquitoes of their own.

Grants for researchers investigating the gut microbiota and its role in human health.