iiinova — where your digital self keeps evolving

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Nereo Kalebic @nereokalebic.bsky.social · 21/05/2025

Three amazing days of the #neurogen2025 conference at @humantechnopole.bsky.social in Milan. Many thanks to all the participants, speakers and fellow co-organizers. We heard fantastic talks in #neurodevelopment #brainevolution #cancerneuroscience #neuroimmunology #neurodegeneration #neurodiversity

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Debby Silver @debbysilver.bsky.social · 14/05/2025

Thrilled to share our latest study out in @natureportfolio.nature.com led by the fantastically talented Jing Liu. Our study provides insight into a long standing question in biology: What molecular features make us uniquely human and how do these function? www.nature.com/articles/s41...

nature.com

A human-specific enhancer fine-tunes radial glia potency and corticogenesis - Nature

HARE5, a human accelerated region enhancer, modulates cortical development by influencing neural progenitor cell behaviour, leading to an enlarged neocortex with increased functional independence betw...

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Cedric Boeckx @cedricboeckx.bsky.social · 15/05/2025

Excellent work from @silvianeuro.bsky.social lab, led by a brilliant young scholar, @mveronicapravata.bsky.social, on the impact of a mutation in DCHS1 distinguishing sapiens from Neandertals: shifting the ratio between cortical & striatal progenitors (Nice to see work going beyond the cortex) 🧪🧠🧬🧫

biorxiv.org

DCHS1 Modulates Forebrain Proportions in Modern Humans via a Glycosylation Change

Comparative anatomical studies of primates and extinct hominins, including Neanderthals, show that the modern human brain is characterised by a disproportionately enlarged neocortex relative to the st...

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katja heuer @k4tj4.bsky.social · 19/05/2025

Looking forward to amazing days of talks&discussions #neurogen25 –Neurodev, evolution, de-& regeneration, organoids &more at @humantechnopole.bsky.social with @r3rt0.bsky.social Thanks to organisers @nereokalebic.bsky.social @harschnitz.bsky.social Jose Davila-Velderrain,Giuseppe Testa,Elena Taverna

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katja heuer @k4tj4.bsky.social · 19/05/2025

Yukiko Gotoh discussing Gene regulation in response to neuronal activity. What makes intron length of neuronal genes longer? How do neurons manage to transcribe so long genes? at #neurogen25 @nereokalebic.bsky.social @harschnitz.bsky.social @humantechnopole.bsky.social @r3rt0.bsky.social

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Denis Jabaudon @djabaudon.bsky.social · 05/05/2025

Why does the forebrain expand dramatically while other neural regions grow less? Our new publication reveals progenitor metabolism critically shapes region-specific brain growth. Thread below. authors.elsevier.com/a/1k-udL7PXu...

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Rossella Di Giaimo @rossdg.bsky.social · 18/02/2025

Very happy to have contributed a little bit to this beautiful story! Great job by Francesco Di Matteo and @silvianeuro.bsky.social and the all team! Congrats!

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Sergiu P. Pasca @sergiuppasca.bsky.social · 11/12/2024

Our 2024 CSHL conference on human brain development and stem cell models is in full swing, with over 300 participants! This year’s event features exciting new discoveries and dynamic discussions, driven largely by the energy & insights of trainees #Assembloids #Organoids #Brain #CSHL2024Brain

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Rossella Di Giaimo @rossdg.bsky.social · 22/11/2024

Happy to share our story on how we modeled EPM1 epilepsy in human brain #organoids during #neurodevelopment. Thanks to Silvia Cappello and all the authors!!! #organoids&assembloidsfeed

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M. Veronica Pravata @mveronicapravata.bsky.social · 22/11/2024

My first paper as lead author as a postdoc is out on bioRxiv! We show how CSTB influences ganglionic eminence development via intrinsic and extrinsic mechanisms. Huge thanks to @rossdg.bsky.social, Silvia Cappello, and the team for their collaboration on this exciting work!

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