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Rosa HP Sca

@rosca26.bsky.social
349 followers 897 following 9 posts

Postdoc'ing @WashU 👩🏻‍🔬 AHA fellow 🫀 Rare musculoskeletal diseases & ion channels🔬 Bookworm 📚 avocaddicted 🥑 4strings lover 🎻

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Reposted by Rosa HP Sca
MAGIC @magic-horizon.bsky.social · 12/05/2026
🔬 A closer look at one of our 3D muscle constructs after 14 days in culture. Confocal imaging reveals organised muscle fibres, nuclei, calcium release channels, and mitochondria – key features we check before modelling disease or testing therapies. #Microscopy #MuscleResearch #MAGIC
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CT Rare Advocate @rarectadvocate.com · 17/09/2026
Andersen-Tawil Syndrome (ATS) combines episodic muscle paralysis, dangerous heart arrhythmias, and distinctive facial features, caused mainly by mutations in the KCNJ2 potassium channel gene. Learn more: dub.sh/ATS1 You may be rare, but you're not alone! #rareDisease #rareDiseaseAwareness
Info card for Andersen-Tawil Syndrome (ATS), a rare potassium-channel disorder estimated to affect about one in one million people. The card notes it is caused mainly by KCNJ2 gene mutations and combines episodic muscle paralysis with heart-rhythm abnormalities. Key symptoms include muscle weakness, a prolonged QT interval, and distinctive facial features. Footer reads: "You may be rare, but you're not alone! rarectadvocate.com"
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National Organization for Rare Disorders (NORD) @nordrare.bsky.social · 16/09/2026
NORD applauds Reps. Bilirakis, Barragán, Cammack, Auchincloss, Kean and Mullin for introducing the Priority for Pediatric Cures Act to make the Rare #Pediatric Disease #PRV Program permanent. On behalf of children with #RareDiseases, NORD strongly urges Congress to pass this bipartisan legislation.
"For children and families affected by rare diseases, the need for new treatments is urgent. The Rare Pediatric Disease PRV Program has been an important incentive for encouraging investment and innovation in therapies for serious and life-threatening rare pediatric diseases," Kathryn Lowell, Executive Vice President of Government Affairs at NORD, the National Organization for Rare Disorders.
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St. Louis Public Radio @stlpublicradio.bsky.social · 15/09/2026
St. Louis is now considered a certified safe and welcoming city for immigrants following a designation from Welcoming America. The certification recognizes the city’s work in economic development, civic engagement, equitable access and safe communities.
stlpr.org
St. Louis recognized as a welcoming community by national immigrant group
The nonprofit Welcoming America has designated 50 cities and counties in the U.S. as welcoming for immigrants. It evaluates them based on seven criteria, including economic development, civic…
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Myotonic Dystrophy Foundation @myotonicstrong.bsky.social · 08/09/2026
Myotonic dystrophy is the most common form of adult muscular dystrophy and is considered the most variable of all known conditions. 📣 Help make it the most well-known on International #myotonicDystrophy Awareness Day, September 15! 💚🔗Learn more at: www.myotonic.org/internationa... 
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Colin Nichols Lab @colinnicholslab.bsky.social · 14/09/2026
New lab members, new lab pic! 🧪
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APS Publications @apspublications.bsky.social · 13/04/2026
Check out this great review by Tessa Garrud et al., Potassium channels in vascular smooth muscle cells 🖱️ ow.ly/C2kB50YCOGy #PotassiumChannel #SmoothMuscle #Vascular
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St. Louis Public Library @stlpubliclibrary.bsky.social · 09/09/2026
It’s #WAYRW! This week we’re reading “Dear Genius: The Letters of Ursula Nordstrom” by Ursula Nordstrom. What are you reading this week?
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Kevin Murach @kevinmurachphd.bsky.social · 06/01/2025
A really nice special issue in @jphysiol.bsky.social by Dr. Chris Sundberg “Physiology of ageing skeletal muscle and the protective effects of exercise” feat. some work by our lab and many others! Check it out @myoblue.bsky.social physoc.onlinelibrary.wiley.com/toc/14697793...
physoc.onlinelibrary.wiley.com
Special Issue: Physiology of ageing skeletal muscle and the protective effects of exercise: The Journal of Physiology: Vol 603, No 1
<em>The Journal of Physiology</em> publishes research in all areas of physiology and pathophysiology that illustrates new physiological principles or mechanisms.
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MDI Biological Laboratory @mdibl.org · 16/12/2024
"Muscle Power" This image by Assistant Prof. Romain Madelaine & Research Assistant Caroline Halluin in 2021, depicts muscle tissue in #zebrafish; green slow fibers, magenta fast fibers & red mitochondria in skeletal muscle fibers are lit up using #fluorescentprotein technology. 🧪🤝 #microscopymonday
zebrafish muscle under a microscope
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Colin Nichols Lab @colinnicholslab.bsky.social · 27/08/2026
Check out our new publication "Cognitive Decline, Neurologic Involvement, and Neonatal Crisis in ABCC9-Related Intellectual Disability and Myopathy Syndrome" 🧪 www.neurology.org/doi/10.1212/...
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Journal of General Physiology @jgp.org · 22/06/2026
Will the real KATP please stand up? Kir6.2/SUR2A takes the stand in the tiring case of #SkeletalMuscle fatigue. @rainbowlabuol.bsky.social and @richardbj.bsky.social discuss new work from Scala and Chen et al. @colinnicholslab.bsky.social (rupress.org/jgp/article/...): rupress.org/jgp/article/...
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Journal of General Physiology @jgp.org · 27/05/2026
Subunit composition of the KATP channels that modulate contractility of skeletal muscle during fatigue. New study from Rosa Scala, Yuezhou Chen, Colin G. Nichols @colinnicholslab.bsky.social and colleagues @washumedicine.bsky.social: rupress.org/jgp/article/... #SkeletalMuscle #IonChannels
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Rockefeller University Press @rupress.org · 20/05/2026
In @jgp.org: Using specific gene subunit knockout mice, Scala and Chen et al. @colinnicholslab.bsky.social show that KATP channels formed exclusively of SUR2/Kir6.2 cause delayed fatigue and development of unstimulated force in isolated EDL skeletal muscles rupress.org/jgp/article/...
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C&EN (Chemical & Engineering News) @cenmag.bsky.social · 24/03/2026
The world produces over 450 million metric tons of plastics a year. As these plastics break down, scientists are rushing to get accurate real-world data on how microplastics spread and how exposed we are to them. cen.acs.org/analytical-c... #microplastics #plasticwaste #chemsky 🧪
How do you study microplastics when they’re everywhere?
Microplastics are everywhere, which makes studying them all the more difficult. Labs are doing all they can to be plastic-free but have few common protocols.
by Fintan Burke.
Various samples from the project of Malin Klein, a PhD student in Dr. Fischer’s lab, studying the distribution of microplastics in the air, trees, and soil of Italy’s Abruzzo Apennine region. ----- Dr. Elke Fischer, researcher at the University of Hamburg, heads the microplastics laboratory where environmental samples are analyzed for plastic contamination. The lab focuses on detecting, quantifying, and understanding the impact of microplastics in aquatic and terrestrial ecosystems. Hamburg, Germany, 2026, Foto: © Jonas Wresch
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Stephen Heard @stephenbheard.bsky.social · 20/03/2026
Jeff Houlahan Jeff Houlahan, Ecologist has posted an interesting manuscript about how to do good science. I think parts of it are wrong - but in productive ways, so it's worth reading. My take: scientistseessquirre... 🧪🌍
scientistseessquirrel.wordpress.com
Friday Link: How to do good science
I don’t do Friday Links here on Scientist Sees Squirrel – that’s really more Dynamic Ecology’s jam. But I’m going to make an exception, because I suspect a lot of readers will be interested in a ma…
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Action for Happiness @actionhappiness.bsky.social · 13/03/2026
Sleep is self-care for a happier mind. 😴✨ • Sleep helps regulate our mood and emotions. • Poor sleep is linked to higher stress and anxiety. • Well-rested people cope better with challenges. • Lack of sleep can reduce kindness and empathy. This World Sleep Day, make rest a priority. 💙
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Myasthenia Gravis News @mgnews.bsky.social · 11/03/2026
You are stronger than you think and capable of more than you know. #InvisibleIllness
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EURORDIS-Rare Diseases Europe @eurordis.bsky.social · 12/03/2026
At #ECRD2026, three parallel tracks on 3 June will explore key rare disease challenges: 🔬 Therapies & medical devices 🧬 Diagnosis, research & prevention ❤️ Evidence-based holistic care Discover the sessions shaping these discussions: go.eurordis.org/ecrd-postersbluesky
Audience attentively listening at a conference, with overlapping text saying: be part of the action.
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Colin Nichols Lab @colinnicholslab.bsky.social · 03/03/2026
Check out our new publication "Cantu syndrome–associated SUR2[H60Y] mutation confers selective gain of function on Kir6.1 ATP-sensitive potassium channels" 🧪 www.jbc.org/article/S002... A 🧵 1/n
jbc.org
Cantu syndrome–associated SUR2[H60Y] mutation confers selective gain of function on Kir6.1 ATP-sensitive potassium channels
Gain-of-function (GOF) mutations in either Kir6.1 (encoded by KCNJ8) or SUR2 (encoded by ABCC9) are causally associated with Cantu syndrome (CS), characterized by coarse facial appearance, hypertricho...
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Rare Disease Day Official @rarediseaseday.bsky.social · 28/02/2026
🌍 It’s #RareDiseaseDay 2026! 💜 Today we stand with the 300 million people living with a rare disease. Together, we’re showing our colours, raising awareness, and inspiring change by talking about what equity means to us. 👉 Read more: go.rarediseaseday.org/NEWS
“It’s Rare Disease Day!” with the Rare Disease Day hand logo and the website” The background is a blue and purple gradient.
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Rachel W. Martin @rwmartin.bsky.social · 23/02/2026
If you’re at #BPS2026, go look at Poster B49. Caroline Cannistra has some very detailed all-atom simulations of HIV capsid protein, and SHE CROCHETED A MODEL OF IT to demonstrate the dynamics.
Crocheted model of a two-domain, mostly helical protein next to Caroline’s hand. Each domain is about the same size as her hand.
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Biophysical Society @biophysicalsoc.bsky.social · 21/02/2026
Make your lab more sustainable! Join us for the panel discussion "Small Actions, Big Impact: Practical Steps to a Sustainable Laboratory" on Sunday from 1-2:30PM in room 153. #bps2026
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🎃 Spooky Shoshana 🎃 @shoshana.bsky.social · 23/11/2025
Boston's Mayor Wu playing with Yo-Yo Ma at Symphony Hall
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Action for Happiness @actionhappiness.bsky.social · 14/10/2025
Don’t forget to be grateful for what you DO have. The little things make life big Image: www.instagram.com/happyvibes_w...
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Rosa HP Sca @rosca26.bsky.social · 14/10/2025
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Colin Nichols Lab @colinnicholslab.bsky.social · 07/10/2025
Check out our new publication "Treatment of overactive KATP channels with glibenclamide in a zebrafish model and a clinical trial in humans with Cantú syndrome" 🧪 @nature.com www.nature.com/articles/s41...
nature.com
Treatment of overactive KATP channels with glibenclamide in a zebrafish model and a clinical trial in humans with Cantú syndrome - Scientific Reports
Scientific Reports - Treatment of overactive KATP channels with glibenclamide in a zebrafish model and a clinical trial in humans with Cantú syndrome
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Colin Nichols Lab @colinnicholslab.bsky.social · 07/10/2025
Check out our new publication "Muscle fatigue arising intrinsically from SUR2- but not Kir6.1-dependent gain-of-function in Cantu syndrome mice" 🧪 @rosca26.bsky.social A 🧵 1/n
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Rosa HP Sca @rosca26.bsky.social · 07/10/2025
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Colin Nichols Lab @colinnicholslab.bsky.social · 22/05/2025
Check out our new publication "Paradoxical Maturity-Onset Diabetes of the Young Arising From Loss-of-Function Mutations in ATP-Sensitive Potassium Channels" 🧪 diabetesjournals.org/diabetes/art... @rosca26.bsky.social A 🧵 1/n
diabetesjournals.org
Paradoxical Maturity-Onset Diabetes of the Young Arising From Loss-of-Function Mutations in ATP-Sensitive Potassium Channels
Pancreatic β-cell ATP-sensitive K+ (KATP) channel closure underlies electrical excitability and insulin release, but loss or inhibition of KATP channels ca
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Colin Nichols Lab @colinnicholslab.bsky.social · 17/05/2025
Next Monday! 🧪
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Colin Nichols Lab @colinnicholslab.bsky.social · 05/05/2025
Join us today for a new exciting CIMED seminar! 🧪 @osamaharraz.bsky.social
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Colin Nichols Lab @colinnicholslab.bsky.social · 07/04/2025
Join us today for a new exciting CIMED seminar! 🧪
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Literland @literland.bsky.social · 28/03/2025
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Daniel MacPhee 🇨🇦 @d-macphee.bsky.social · 23/03/2025
“"What we've shown in this paper is that the epithelial cells can communicate with the macrophages,"… "Our hypothesis is that their cross talk potentially provides an environment that's conducive to the development of the disease." 🧪 #ReproSky #MedSky #ObGynSky medicalxpress.com/news/2025-03...
medicalxpress.com
Researchers make progress toward non-hormonal treatment for endometriosis
Roughly 200 million women around the world suffer from endometriosis, a condition that causes tissue from the lining of the uterus to grow in places outside of the uterus. The condition can be excepti...
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Biophysical Society @biophysicalsoc.bsky.social · 22/03/2025
To celebrate the Biophysics Week, the Spanish Biophysical Society has coordinated a series of "Biophyzza Connection" Affiliate Events locally organized by its members and sponsored by Domino’s Pizza. Explore and find an event close to you!
buff.ly
The Biophyzza Connection 2025 | Spanish Biophysical Society
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WWF EU @wwf.eu · 20/03/2025
🔔Join us on 25 March to discuss the green steel transition! #EuropeanSteel is at a crossroads: 🔥 Stick with outdated, coal-based tech 💚 Upgrade to #GreenSteel & boost #recycling Register 👇 www.eventbrite.com/e/report-lau... @e3g.bsky.social @beyondfossilfuels.bsky.social
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Action for Happiness @actionhappiness.bsky.social · 19/03/2025
March 20th is the UN International Day of Happiness. This year’s theme is 'Caring and Sharing' and we’re encouraging 1 million extra acts of caring and sharing. You can be part of it! Please help spread the word 🙏💕🌎 #InternationalDayOfHappiness dayofhappiness.net
dayofhappiness.net
International Day of Happiness - 20 March
Celebrate #InternationalDayOfHappiness on 20 March. Join the Action for Happiness community and help create a happier and kinder world, together.
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Compound Interest | Chemistry infographics @compoundchem.com · 17/03/2025
Happy #StPatricksDay! ☘️ What makes the bubbles in a glass of Guinness fall, and what gives the beer its dark colour? This graphic in @cenmag.bsky.social has the answers: cen.acs.org/articles/93/... #ChemSky 🧪
Infographic on the chemistry of Guinness. It details how a mix of carbon dioxide and nitrogen is responsible for the bubbles, iso-alpha-acids are responsible for bitterness, and melanoidins are responsible for the beer's dark colour.
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Rosa HP Sca @rosca26.bsky.social · 17/03/2025
«Ridateci la Statua della Libertà» www.ilpost.it/2025/03/17/r...
ilpost.it
«Ridateci la Statua della Libertà» - Il Post
Lo ha chiesto un politico francese criticando le politiche di Donald Trump contro la ricerca scientifica
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Ian L Morgan @ianlmorgan.bsky.social · 17/03/2025
I just read this study on using humor to be a better science communicator. What's your favorite use of humor in a paper or talk? Here's one related to my field. jcom.sissa.it/article/pubi... 🧪
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Rosa HP Sca @rosca26.bsky.social · 15/03/2025
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WHO @who.int · 14/03/2025
If you don’t get your child vaccinated against measles, it can put them at a high risk of this serious infection, which can lead to severe complications or even death. Make sure your child’s measles vaccination is up to date.
If you don’t get your child vaccinated against measles, it can put them at a high risk of this serious infection, which can lead to severe complications or even death.

Make sure your child’s measles vaccination is up to date.
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Rosa HP Sca @rosca26.bsky.social · 08/03/2025
@standupforscience.bsky.social in Jefferson City MO 🧪👩🏻‍🔬🥼🔬 www.stlpr.org/government-p...
stlpr.org
SLU, WashU researchers among those at state Capitol protesting science funding cuts
The protest was organized as part of a nationwide Stand Up for Science effort, with thousands gathering at dozens of rallies across the country.
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Rosa HP Sca @rosca26.bsky.social · 08/03/2025
@standupforscience.bsky.social in St. Louis MO 🧪👩🏻‍🔬🥼🔬 www.stltoday.com/news/local/m...
stltoday.com
St. Louis joins nation in 'Stand Up For Science' protests
Researchers, doctors, patients and supporters ventured out of labs, hospitals and offices Friday to fight against what they call a blitz on life-saving science by the Trump administration.
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Bethany Brookshire @beebrookshire.bsky.social · 07/03/2025
At @standupforscience.bsky.social and the signs are statistically significantly excellent
A person in a mask holding a painting that says “hands off my transgenic mice”
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Rebekah Evans @cellularscale.bsky.social · 07/03/2025
#standupforscience
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Stand Up for Science! @standupforscience.net · 07/03/2025
TODAY IS THE DAY! 🧪☀️⬇️ Join us at the Lincoln Memorial or your local site to Stand Up for Science!
Flyer for stand up for science--more information available at www.standupforscience2025.org
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Colin Nichols Lab @colinnicholslab.bsky.social · 03/03/2025
Join us today for a new exciting CIMED seminar! 🧪
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George Takei @georgetakei.bsky.social · 01/03/2025
A reminder for these times.
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