This study benchmarks 43 computational methods for identifying topologically associating domains (TADs), presents a tool based on a consensus strategy that leads to improved performance, and releases ...

HaploC-tools infer and compare haplotype-specific chromosome 3D structures, copy number, boundaries, and compartments in >100 Hi-C datasets, revealing widespread haplotype-specific chromatin organi...

Cancer evolution is a multi-faceted process and a major clinical challenge. Indeed, tumors constantly change as they progress through multiple mechanisms, the understanding of which is critical to an…

Cancer evolution is a multi-faceted process and a major clinical challenge. Indeed, tumors constantly change as they progress through multiple mechanisms, the understanding of which is critical to an…

Cancer evolution is a multi-faceted process and a major clinical challenge. Indeed, tumors constantly change as they progress through multiple mechanisms, the understanding of which is critical to an…

A novel multistep strategy reveals how parent-of-origin effects shape complex traits in large-scale biobanks.

The 2nd European Cancer Dependency Map Symposium is a scientific event open to the national and international scientific community working in computational genomics, pharmacogenomics, and therapeutic ...

The Institute of Oncology Research (IOR) The IOR, affiliated with the Università della Svizzera italiana (USI), is located in a brand-new, high-tech research building that hosts more than 20 differ

A lack of standardized benchmarks is hindering progress and patient benefits

We a seeking applications for a computational postdoctoral fellow with expertise in cancer epigenomics, chromatin biology, and data-driven research.

Des scientifiques de l'EPFL ont développé des "lymphomoïdes". Ces avatars de tumeurs devraient permettre de tester en laboratoire l'efficacité des traitements du lymphome et de mieux prédire les répon...