iiinova — where your digital self keeps evolving

Reposted by Pugh Lab

Princess Margaret Cancer Centre @pmresearch-uhn.bsky.social · 24/02/2026

Exciting new research in advanced melanoma shows sequencing T-cells can help predict and monitor response to adoptive cell transfer, a treatment using a patient’s own immune cells to attack cancer. @uhnresearch.ca @uhn.ca @oicr.on.ca doi.org/10.1186/s130...

051

Reposted by Pugh Lab

Marathon of Hope Cancer Centres Network @marathonofhope.bsky.social · 11/12/2025

🍁🔬MOHCCN Clinician Scientist Awards 2026 Launch🍁🔬 The MOHCCN Clinician Scientist Awards provide funding to young investigators looking to conduct high-quality, clinically-related research in precision oncology. Letter of Intent due: January 22, 2026 Learn more: tinyurl.com/dn774xa5

082

Reposted by Pugh Lab

Marathon of Hope Cancer Centres Network @marathonofhope.bsky.social · 04/11/2025

Today is a great day for cancer research in Canada and, more importantly, for the health of all Canadians! We sincerely thank the Government of Canada for its ongoing commitment to improve the lives of Canadians diagnosed with cancer through the work of the Network. Full statement ▶️ bit.ly/4oSuFhp

071

Reposted by Pugh Lab

Research at Sinai Health @sinaihealth.bsky.social · 06/10/2025

🎉 Congratulations to LTRI alumna Dr. Mary Brunkow on receiving the 2025 Nobel Prize in Physiology or Medicine for her groundbreaking immune system research. Read the story: www.sinaihealth.ca/news/ltri-al...

042

Reposted by Pugh Lab

Daniel Durocher @durocher1.bsky.social · 28/08/2025

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!

0135169

Reposted by Pugh Lab

Cancer Genomics Consortium @cgconsortium.bsky.social · 25/08/2025

Mark your calendar with #CGCAnnual2026—we look forward to seeing you in Houston next year! #CGCAnnual2026 #genomics #cancer #research #genetics #clinicaltesting #bioinformatics #cytogenetics #molecular

022

Reposted by Pugh Lab

Scott McGrath @smcgrath.phd · 14/06/2025

For those of you who may not have known him, Dr. Atul Butte, a pioneer in informatics, was the winner of the 2024 Morris F. Collen award, a pinnacle achievement in our field, as part of his storied career. His passing is a major loss to us all. RIP Dr. Butte #MedSky

vimeo.com

2024 Morris F. Collen Award Winner - Atul Butte, MD, PhD, FACMI

This is "2024 Morris F. Collen Award Winner - Atul Butte, MD, PhD, FACMI" by AMIA on Vimeo, the home for high quality videos and the people who love them.

43411

Reposted by Pugh Lab

Federico Gaiti @fgaiti.bsky.social · 16/05/2025

Excited to share our first lab paper, now published in Developmental Cell @cellpress.bsky.social ! 🧠 How do glioblastoma (GBM) cells invade the brain, and what enables them to spread so effectively?

2154

Reposted by Pugh Lab

Princess Margaret Cancer Centre @pmresearch-uhn.bsky.social · 12/05/2025

Cell therapy has revolutionized cancer treatment. Now, its potential is expanding far beyond. Join us for the launch of the Centre for Immunology to Immunotherapy at UHN to explore the future of cell therapy: events.myconferencesuite.com/Ci2iSymposiu...

094

Reposted by Pugh Lab

NEJM.org @nejm.org · 13/04/2025

A recent study shows how extrachromosomal DNA contributes to tumor heterogeneity and may drive cancer progression. Learn more: nej.md/42jfYdH #MedSky #Oncology #Genetics

An illustrated diagram of the biologic features of extrachromosomal DNAs

1256

Reposted by Pugh Lab

Princess Margaret Cancer Centre @pmresearch-uhn.bsky.social · 04/04/2025

The Allan Slaight Breakthrough Forum brought together 60+ scientists from Princess Margaret Cancer Centre, Krembil Research Institute, and CAMH to explore the links between cancer, neuroscience, & mental health. Looking forward to the exciting discoveries ahead! www.uhnresearch.ca/news/advanci...

153

Reposted by Pugh Lab

Jim Woodgett @jwoodgett.bsky.social · 03/04/2025

Excellent Op-Ed by Peter Zandstra on improving 🇨🇦 science at a time when 🇺🇸 is throttling their golden goose. Instead of bespoke, targeted & ultimately short term solutions limited to a few people, build a deep, more attractive ecosysyem. The best will thrive. www.theglobeandmail.com/gift/46242ee...

theglobeandmail.com

Canada’s U.S. brain gain is risky without more foundational support for science

Scientists want to come to Canada not only to escape the chaos and uncertainty emerging in U.S. science but also because they are drawn to the energy here

26028

Reposted by Pugh Lab

cBioPortal @cbioportal.bsky.social · 10/03/2025

We're excited to join Bluesky! Follow us for the latest news about cBioPortal.

021

Reposted by Pugh Lab

Mathieu Lupien @matlupien.bsky.social · 12/02/2025

🇨🇦 Fast-track your computational biology/bioinformatics career in cancer research! 🇨🇦 The Lupien Lab is looking to recruit a Postdoctoral Fellow in computational biology/bioinformatics ready for a challenge. Apply now: www.nature.com/naturecareer...

nature.com

Postdoctoral Fellow - Computational - Toronto (Region), Ontario (CA) job with Princess Margaret Cancer Centre | 12836915

We a seeking applications for a computational postdoctoral fellow with expertise in cancer epigenomics, chromatin biology, and data-driven research.

12117

Reposted by Pugh Lab

Nature Reviews Cancer @natrevcancer.nature.com · 27/01/2025

#REVIEW Vallot, Lupien and Lasine describe how epigenomic heterogeneity generates dynamic reservoirs of tumour cell states, which can be leveraged in the design of novel therapies. 📖 👉 bit.ly/40PCQ...

bit.ly

Epigenomic heterogeneity as a source of tumour evolution - Nature Reviews Cancer

Single-cell epigenomic technologies are refining our understanding of cancer evolution.

0148

Reposted by Pugh Lab

Jim Woodgett @jwoodgett.bsky.social · 23/01/2025

Indeed, there are a number of open positions for early career investigators in Toronto. It's a great city in a great country to pursue impactful science.

1117

Reposted by Pugh Lab

Vuk Stambolic @vukstambolic.bsky.social · 23/01/2025

Seems like a perfect day to consider continuing your research career in beautiful Canada! Recruiting an ECR in cancer research, a week left to apply.

1138

Pugh Lab @pughlab.bsky.social · 16/01/2025

Absolutely thrilled to see the next next-generation sequencer arrive on our doorstep. Looking forward to affordable deep dives into cell-free genomes. Will we be able to reconstruct cancer genomes from blood without a biopsy, even for early cancers? We think so!

010