Reposted by Philippe Domenech Manuel Mendoza @longchrom.bsky.social · 22/06/2026This article in Le Monde about French research in general and the CNRS in particular has a few depressing graphs www.lemonde.fr/sciences/art... 46062
Reposted by Philippe Domenech Jon Cooper @joncooper-us.bsky.social · 27/02/2026Every senator who voted to confirm RFK Jr owns this tragedy. Every single one. 541167147014
Reposted by Philippe Domenech the computational brain lab @computationalbrain.bsky.social · 07/02/2026Using 7T fMRI, our team found a representation of the probability of the next event in human dlPFC —and it’s highly non-monotonic. Confidence signals, in contrast, were mostly monotonic. doi.org/10.1038/s414... 🧠🟦🧠🤖 0144
Reposted by Philippe Domenech Joao Barbosa @jbarbosa.org · 28/01/2026Thank you Nicole! Nicole's wonderful book 'Elusive Cures' has played an important role in pushing me out of my comfort zone and join forces w/ @philippedomenech.bsky.social and @bellecguill.bsky.social, here. Exciting times ahead for neuroscience. Go read it, if you haven't yet! 1156
Reposted by Philippe Domenech the computational brain lab @computationalbrain.bsky.social · 07/02/2026Using calcium imaging in macaque PFC during a meta–WM task, we show that PFC jointly encodes remembered locations + uncertainty. PFC integrates WM strength + cues into a meta-WM signal that guides behavior. A collab btw our team and Liping Wang group doi.org/10.1016/j.ne... 🧠🟦🧠🤖 1132
Reposted by Philippe Domenech Joao Barbosa @jbarbosa.org · 27/01/2026Postdoc position in Paris: come help develop new generation human brain computer interfaces ⚡🧠💻 Interested? Contact me if you have experience with machine learning (e.g. simulation-based inference, RL, generative/diffusion models) or dynamical systems. See below for + details and retweet 🙏 37456
Philippe Domenech @philippedomenech.bsky.social · 15/01/2026🚨 !!! New preprint !!! 🚨 MULTIMODHAL (phase 3, multicenter double-blind RCT): fMRI “symptom-capture”–guided neuronavigation significantly improves 1-Hz rTMS outcomes for drug-resistant auditory verbal hallucinations vs standard T3P3 targeting. 🧠🟦 #rTMS #Psychiatry #Schizophrenia #fMRImedrxiv.org 052
Reposted by Philippe Domenech Hannah Ritchie @hannahritchie.bsky.social · 09/06/2025Tuberculosis still kills around 1.3 million people every year. It was once a massive killer in Europe and the US, but not anymore. How did these countries manage to tackle it? Our first article on TB in a three-part series: ourworldindata.org/tuberculosis... 67623
Reposted by Philippe Domenech Stand Up for Science Paris et région parisienne @sufs-paris-rp.bsky.social · 19/06/2025Les visas des chercheurs, des universitaires et des étudiants pour les Etats-Unis ne seront pas accordés à celles et ceux qui ont exprimé de l'hostilité au régime autoritaire de Trump. Ces refus de visa se feront par analyse des posts sur les réseaux sociaux. www.nytimes.com/2025/06/18/u...nytimes.comU.S. to Review Social Media Posts of Student and Scholar Visa Applicants 1094106
Philippe Domenech @philippedomenech.bsky.social · 08/06/2025www.lemonde.fr/economie/art...lemonde.frDerrière la grave pénurie française de médicaments psychotropes, une défaillance industriellePlus de la moitié des pharmacies disposent de moins d’un jour de stock de traitements-clés pour les personnes bipolaires ou en dépression. L’arrêt à l’automne 2024 d’une usine grecque qui fabrique, po... 031
Reposted by Philippe Domenech Vinny Costa @vincentcostaphd.bsky.social · 06/06/2025This is fantastic, causal work demonstrating the basal ganglia’s role in explore-exploit decision making www.nature.com/articles/s41...nature.comBasal ganglia deep brain stimulation restores cognitive flexibility and exploration-exploitation balance disrupted by NMDA-R antagonism - Nature CommunicationsDeep brain stimulation of the basal ganglia restores cognitive flexibility and rebalances exploration disrupted by NMDA receptor antagonism in nonhuman primates, offering insights into the neural basi... 0177
Reposted by Philippe Domenech Jack Kosmicki @jakphd.bsky.social · 06/06/2025Year ago, the prevailing attitude was that deep learning would significantly improve polygenic risk scores (or anything else, to be fair). A rather important set of negative results indicating that isn't the case (though I imagine many will still try). nature.com/articles/s41... 3207
Reposted by Philippe Domenech Stefano Palminteri @stepalminteri.bsky.social · 26/05/2025New in Nature MentalHealth! with Vrizzi, Najar, Lemogne, and @mael-lebreton.bsky.social We tested whether behavioural and RL-based model parameters are test-retest reliable and predict mental health traits. The result? Not really. A cautionary tale for comp. psychiatry doi.org/10.1038/s442...doi.orgBehavioral, computational and self-reported measures of reward and punishment sensitivity as predictors of mental health characteristics - Nature Mental HealthReinforcement learning task-based behavioral and computational measures displayed low test–retest reliability at the individual level. Also in contrast to self-assessed personality measures, behaviora... 25428
Reposted by Philippe Domenech Imaging Neuroscience @imagingneurosci.bsky.social · 07/05/2025New paper in Imaging Neuroscience by Britta U. Westner, Tim M. Tierney, et al: Cycling on the Freeway: The perilous state of open-source neuroscience software doi.org/10.1162/imag... 03522
Reposted by Philippe Domenech American Statistical Association History of Statistics @hos-asa.bsky.social · 11/05/2025#OTD 1920 Edward Kaplan b (d 26 Sep 2006) Best known for 1958 "sleeper hit" paper describing what is now known as the Kaplan–Meier product-limit statistic for survival & lifetime data. Now one of the most cited statistics papers of modern times, it took >12 yrs to catch on. 🧵/6 171
Reposted by Philippe Domenech This skeet will self destruct @pardoguerra.bsky.social · 05/05/2025$500 million is… less than 1.25% of the NIH’s 2024 budget. When I say there is no capacity to absorb the shock, I mean it. 18961336
Reposted by Philippe Domenech Randall Munroe @xkcd.com · 25/04/2025PhD Timeline xkcd.com/3081 5865979520444
Reposted by Philippe Domenech The New York Times @nytimes.com · 25/04/2025Breaking News: A federal prosecutor interrogated the The New England Journal of Medicine — which is considered the world’s most prestigious medical journal — in what its editor described as a “vaguely threatening” letter.nytimes.com‘Vaguely Threatening’: Federal Prosecutor Queries Leading Medical JournalThe New England Journal of Medicine received a letter suggesting that it was biased and compromised by external pressure. Other journals have also received the letter. 20632711524
Reposted by Philippe Domenech Dr Susan Oliver (PhD) @drsusanoliver.bsky.social · 25/04/2025New study in JAMA. Modelling shows that at current state-level vaccination rates, measles may become endemic again in the USA. If rates continue to decline, ditto for rubella, poliomyelitis and diphtheria, leading to many preventable hospitalisations and deaths. jamanetwork.com/journals/jam...jamanetwork.comModeling Reemergence of Vaccine-Eliminated Infectious Diseases Under Declining Vaccination in the USThis study estimates the number of cases and complications in the US under scenarios of declining childhood vaccination for measles, rubella, poliomyelitis, and diphtheria. 16308121
Reposted by Philippe Domenech Cole Hurwitz @colehurwitz.bsky.social · 21/04/2025Thrilled to share our state-of-the-art method for in vivo cell-type classification and brain region localization, NEMO, which is now now a spotlight at @iclr-conf.bsky.social ! We use NEMO to characterize the electrophysiological diversity of cell-types across the entire mouse brain. 🐭 🧪 🧠 16918
Reposted by Philippe Domenech Timothy Caulfield @caulfieldtim.bsky.social · 20/04/2025Such a dangerous idea. US attorney demands scientific journal explain how it ensures 'viewpoint diversity' www.nbcnews.com/science/scie... Process of science – a human endeavour – full of biases. Key to recognize & counter. But can’t let false balance & middle ground fallacies taint research.nbcnews.comU.S. attorney demands scientific journal explain how it ensures 'viewpoint diversity'The unusual letter caught the attention of First Amendment groups and some scientists, who raised concerns it was designed to suppress academic and scientific freedom. 1315039
Reposted by Philippe Domenech Earl K. Miller @earlkmiller.bsky.social · 20/04/2025Trump proposes massive NIH budget cut and reorganization www.science.org/content/arti...science.orgTrump proposes massive NIH budget cut and reorganizationWill Republican-led Congress support a 44% decrease for world’s largest medical research funder? 1149
Philippe Domenech @philippedomenech.bsky.social · 20/04/2025english.elpais.com/internationa...english.elpais.comEU to double funding to attract US scientists fleeing TrumpThe European Commission acknowledges its interest in the ‘opportunity’ generated by the cuts and obstacles promoted by the Republican administration 083
Reposted by Philippe Domenech Nature @nature.com · 20/04/2025The world now has a plan for when the next global pandemic hits go.nature.com/43X27wggo.nature.comFirst global pandemic treaty agreed — without the USThe World Health Organization accord promotes sharing scientific data in exchange for more equitable distribution of drugs and vaccines. 515044
Reposted by Philippe Domenech Laura Haynes👩🔬⚾️🐾💙 @drlaurahaynes.bsky.social · 19/04/2025My first Saturday morning coffee on my deck this season 😎☕️ 408202732518
Philippe Domenech @philippedomenech.bsky.social · 18/04/2025www.lemonde.fr/sciences/art...lemonde.frEmmanuel Macron appelle les chercheurs internationaux à « choisir » la France et l’Europe, avec un « rendez-vous le 5 mai »Avant ce rendez-vous, une plateforme baptisée « Choose France for Science » a été lancée jeudi par le gouvernement. Il la présente comme « une première étape pour préparer l’accueil des chercheurs int... 010
Reposted by Philippe Domenech Paul Chopelin @paulchopelin.bsky.social · 17/04/2025Intéressante tribune sur l'illusion d'une université française attractive pour les chercheurs américains tentés par l'exil. Ou de l'incapacité de regarder en face les conséquences de sa propre politique. Terrible absence de sens des responsabilités... www.lemonde.fr/sciences/art...lemonde.frAccueillir les chercheurs américains en France , « une ambition louable, mais irréaliste »TRIBUNE. L’universitaire Théo Besson rappelle, dans une tribune au « Monde », que le manque criant d’investissement ainsi que le niveau des salaires dans la recherche française interdisent de fantasme... 615467
Reposted by Philippe Domenech Randy McIntosh @ar0mcintosh.bsky.social · 13/04/2025"The work we reviewed here supports an alternative view that the manifold and circuit approaches to cognition are inseparable." Can I get an amen? 😊 www.nature.com/articles/s41...nature.comA unifying perspective on neural manifolds and circuits for cognition - Nature Reviews NeuroscienceNeural manifolds can shed light on how heterogeneous neuronal population activity drives neural computations, but linking these insights to the underlying neuronal connectivity is challenging. Engel a... 15611
Reposted by Philippe Domenech David Masson @psymassondavid.bsky.social · 12/04/2025"Quand Nicolas Demorand "révèle" qu'il souffre de trouble bipolaire de type 2, il ne dit rien de son affaire" 😡 En tant que psychiatre, je suis vraiment très en colère à la lecture de cet article de Charlie Hebdo de cette semaine. Un post n'est pas suffisant pour l'exprimer⬇️ 1416777
Reposted by Philippe Domenech Marieke van Vugt @mvugt.bsky.social · 11/04/2025Tips for getting started with Bayesian statistics dx.plos.org/10.1371/jour...dx.plos.orgTen quick tips to get you started with Bayesian statistics 12713
Reposted by Philippe Domenech Nils Kolling @nilskolling.bsky.social · 08/04/2025Registrations for the Symposium for the Biology of decision making (SBDM) in Lyon 2025 are finally open! sbdm2025.github.io Please spread the message! 02310
Reposted by Philippe Domenech Sami Beaumont @samibeaumont.bsky.social · 04/04/2025Excited to share our preprint: "Recasting adaptation as strategy inference". This work explores how humans spontaneously adapt to changes by inferring strategies, rather than relying on incremental learning.@philippedomenech.bsky.social @khamascience.bsky.social @computationalbrain.bsky.social 🧠🟦 🧠🤖tinyurl.comRecasting adaptation as strategy inferenceFlexible adaptation to uncertain and changing environments requires dynamic adjustments in behavioral strategies. While classical learning theories emphasize incremental strengthening of local stimulu... 22913
Reposted by Philippe Domenech Dr. Thibault Le Hégarat @thibaultlh.bsky.social · 07/04/2025L’excellent Soulcié pour L’Est Républicain. 9879285
Reposted by Philippe Domenech Lucie Berkovitch @lucieberko.bsky.social · 07/04/2025📣 🌈 🩺 Pétition et tribune dans @lemonde.fr : "Avant de mourir, peut-on mieux vivre ? Pour un accès compassionnel aux psychédéliques en fin de vie" par la Section Médecine Psychédélique de l'AFPBNchange.orgSignez la pétitionPour un accès compassionnel aux traitements psychédéliques en fin de vie 152
Reposted by Philippe Domenech Die Sankoré-Schriften @sankoreschriften.bsky.social · 04/04/2025Improvements to brain-computer interfaces are bringing the technology closer to natural conversational speed. #neuroskyence #braincomputerinterface #speechnature.comBrain implant translates thoughts to speech in an instantImprovements to brain–computer interfaces are bringing the technology closer to natural conversational speed. 2298
Reposted by Philippe Domenech Darren Dahly @statsepi.bsky.social · 06/04/2025American scientists aren't special. It's the institutions, and willingness to spend on research, that set them apart. Similarly invest here, and you will naturally attract the best talent from *everywhere*. www.politico.eu/article/euro...politico.euEurope to burned American scientists: We’ll take you inThe EU’s body for scientific research, as well as local, regional and national governments, are mobilizing to poach top U.S. scholars. 515044
Reposted by Philippe Domenech Kevin Korb @kbkorb.bsky.social · 05/04/2025Eric Topol reviews recent studies of the shingles vaccine and dementia. 🧪erictopol.substack.comThe Shingles Vaccine and Reduction of DementiaA compelling new study adds to the body of data supporting some protection provided by the vaccine 17015
Reposted by Philippe Domenech Ethan Solomon @esolomon.bsky.social · 03/04/2025When we use TMS to treat depression, we think it alters neural activity in a deep brain structure known as the subgenual anterior cingulate (sgACC). But this is hard to test directly, until our preprint with @coreykeller.bsky.social, @neuro-engineer.bsky.social, Nick Trapp, and Aaron Boes (UIowa) 1/biorxiv.orgDLPFC Stimulation Suppresses High-Frequency Neural Activity in the Human sgACCTranscranial magnetic stimulation (TMS) to the dorsolateral prefrontal cortex (DLPFC) is hypothesized to relieve symptoms of depression by inhibiting activity in the subgenual anterior cingulate corte... 13416
Reposted by Philippe Domenech Earl K. Miller @earlkmiller.bsky.social · 02/04/2025New results! Working memory is read out via a theta (3-6 Hz) traveling wave sweeping across cortex. Working memory readout varies with frontal theta rhythms www.biorxiv.org/content/10.1... #neurosciencebiorxiv.orgWorking memory readout varies with frontal theta rhythmsIncreasing evidence suggests that attention varies rhythmically, phase-locked to ongoing cortical oscillations. Here, we report that the phase of theta oscillations (3 to 6 Hz) in the frontal eye fiel... 3488
Philippe Domenech @philippedomenech.bsky.social · 04/04/2025🚨 !!! New preprint !!! 🚨 Excited to share my student @samibeaumont’s latest work, where we demonstrate that inference over putative strategies is sufficient to fully accounts for human adaptation across diverse statistical contexts, when reinforcement learning cannot. 🧠🟦 🧠🤖 #Neuroscience #Preprint 0142
Reposted by Philippe Domenech Michael Okun @michaelokun.bsky.social · 30/03/2025Wouldn't it be cool to be able to stimulate deep w/in the brain w/o the need for brain surgery, and without actually making a physical lesion in the brain (i.e. FUS or pallidotomy)? This paper provides 'proof of concept' that a transcranial ultrasound stimulation (TUS) approach may be achievable. 04013
Reposted by Philippe Domenech -Boulet- @bouletcorp.bsky.social · 29/03/2025Aussi aujourd'hui je retombe par hasard sur ce banger: 111273140
Reposted by Philippe Domenech Nature @nature.com · 25/03/2025An immigration crackdown in the United States is rattling the global research community, with high-profile detentions and deportations of academics stoking fears even for travellers with valid entry documents go.nature.com/4iMw7PVgo.nature.com‘Anxiety is palpable’: detention of researchers at US border spurs travel worriesSeveral high-profile incidents in the past month have scientists on edge. 47426
Reposted by Philippe Domenech David Masson @psymassondavid.bsky.social · 23/03/2025À faire absolument savoir. Le safran n'est PAS un traitement à recommander dans le #TDAH. Ça n'a aucune efficacité démontrée. Ce qui est vendu, c'est du rêve en réalité. Pour 32,90€ par mois (!!!) non remboursé, ça fait cher pour du vent. #SanteMentaleBusiness 87337
Reposted by Philippe Domenech Carl T. Bergstrom @carlbergstrom.com · 19/03/20251. For the past thirty years I've had the best job in the world. I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all. 382585927
Reposted by Philippe Domenech Don Moynihan @donmoyn.bsky.social · 19/03/2025If you are visiting the United States, having a negative view of Trump is enough to get you denied entry. If this was coming out of Russia or China, we would deplore such an authoritarian attack on freedom of expression. 17864602891
Reposted by Philippe Domenech Joao Barbosa @jbarbosa.org · 19/02/2025Are you a (computational) neuroscientist looking for a postdoc? Come to Paris! There are plenty of great labs always looking for talent, including our own 0207