Among the populations of CD28- T cells, CD8+CD28- T cells show the greatest age-related increase...CD8+CD28- T-cell alterations have been reported in cancer, viral infections, autoimmunity and almost every chronic inflammatory disease. pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov
CD8+CD28- T cells: not only age-related cells but a subset of regulatory T cells