iiinova — where your digital self keeps evolving

Paolo De Los Rios @paolodelosrios.bsky.social · 22/09/2026

This was really fun to work on. Thanks for leading it!

011

Paolo De Los Rios @paolodelosrios.bsky.social · 16/09/2026

Don't miss the opportunity! Jay's research is inspiring, and Lausanne... come on!

041

Reposted by Paolo De Los Rios

Simon Gosden @simongosden.bsky.social · 15/09/2026

I concur

65716

Reposted by Paolo De Los Rios

BertSaysWoof @bertsayswoof.bsky.social · 21/08/2026

Exactly. If you want to steal with impunity you have to do it for capitalism, not personal enjoyment

0653

Reposted by Paolo De Los Rios

Chance the Lawyer @chancethelawyer.bsky.social · 21/08/2026

say what you will about the myriad valid concerns with current LLMs but I personally will never get over the fact that Aaron Swartz was prosecuted to his literal death for downloading JSTOR and then a decade later, they downloaded & ingested the entire world and our IP laws just went ¯\_(ツ)_/¯

4645461568

Paolo De Los Rios @paolodelosrios.bsky.social · 20/08/2026

Nice fella greeting me at the office this morning

110

Reposted by Paolo De Los Rios

Jules @juleswp.eurosky.social · 15/08/2026

« Le biologiste Paul Ehrlich expliquait qu'il faudrait plutôt voir les espèces comme les rivets d’un avion qui maintiennent ensemble les tôles de l’appareil. On peut perdre quelques rivets, ça tient, mais quand on en perd trop, tout explose. »

lemonde.fr

« Préserver et restaurer la nature coûte moins cher que la détruire : pour 1 euro investi dans la biodiversité, on en récupère 8 »

« Les entretiens de “Chaleur humaine” ». Comment faire face aux menaces qui pèsent sur le vivant et les écosystèmes ? La biologiste Tatiana Giraud propose que cela passe par une réorientation des subv...

3290157

Reposted by Paolo De Los Rios

Prof Bill McGuire @profbillmcguire.bsky.social · 08/08/2026

Instead of annexing, the Trump regime and its supporters are simply doing and taking what they want Denmark and the EU should put a stop to this illegal incursion now - using force if need be It is the only thing these fascists understand www.theguardian.com/world/2026/a...

theguardian.com

Greenland issues ‘strong warning’ as Trump-linked oil firm prepares to drill

Island’s government says no approval given after Greenland Energy brings kit ashore for exploratory drilling

1081234677

Paolo De Los Rios @paolodelosrios.bsky.social · 25/07/2026

We are hiring! In the framework of the NCCR Genesis (nccr-genesis.ch) we have a postdoc position to work on the theory of chemical reaction networks in non-equilibrium settings, also in close contact with experimentalists. If interested, apply here programs-recruiting.epfl.ch/positiondeta...

programs-recruiting.epfl.ch

Selectus - Home

153

Reposted by Paolo De Los Rios

Alisia Fadini @alisiafadini.bsky.social · 21/07/2026

Atomic models powered bioAI's first era. Experiments measure more. @rs-station.bsky.social is joining omsf.io to unlock interpretation of raw exp observables at scale (blog👇); we'll partner with @openfold.io, @openbind.bsky.social , and cryo-EM+X-ray facilities to make this routine. Join us!

omsf.io

Open Molecular Software Foundation

Making bonds Building open source software and communities for the molecular sciences.

095

Paolo De Los Rios @paolodelosrios.bsky.social · 21/07/2026

Ok just some D&D-style art. Crates from #MapEffects tutorial, wall and torch from one of their maps, floor, with all its problems, is mine.

110

Paolo De Los Rios @paolodelosrios.bsky.social · 15/07/2026

Absolutely fascinating! I read that bits of these proteins (collagen I think) were detected in fossils too…

021

Paolo De Los Rios @paolodelosrios.bsky.social · 12/07/2026

Very good analogy. That said, pretty useless research because Italians already know how to make perfect pizzas. No further research needed.

020

Reposted by Paolo De Los Rios

🦋 C.G., PhD 🐸 (🪖"Prima" AKA "Battle" to One)🌻 @tcrg2012.bsky.social · 11/07/2026

The grass is actually greener in "THIS" red, white and blue. #ONEV1 #Pinks 🌸 #Voices4Victory

371174412

Paolo De Los Rios @paolodelosrios.bsky.social · 20/06/2026

All’attenzione di Vannacci: “It also makes killings involving coercive control, hate, sexual violence or exploitation first-degree murder. When the victim is a woman, the offense will be formally recognized as femicide” www.onestnetwork.com/onest-brief-...

onestnetwork.com

ONEST Brief: Canada Rewrites the Law, China Consolidates Power, and the Middle East Truce Falters

June 19, 2026 Canada enacted major criminal justice and election-security reforms, China consolidated political control while preparing its economy for prolonged geopolitical pressure, and renewed fi...

000

Paolo De Los Rios @paolodelosrios.bsky.social · 17/06/2026

Not to be missed! Delft is a fantastic place, and the Biophysics/Synthetic Life community in the Netherlands is second to none.

041

Reposted by Paolo De Los Rios

MC Gambetta @mcgambetta.bsky.social · 04/05/2026

Hello all, our lab is recruiting a PhD candidate to study how 3D genome folding impacts gene regulation in development. We're located at the Center for Integrative Genomics department of the University of Lausanne, Switzerland. Please email me if interested. #PhDPosition, #PhDOpportunity

05844

Reposted by Paolo De Los Rios

Juan C. Landoni @jclandoni.bsky.social · 24/04/2026

We're hiring! 🔬🏔️ Looking for curious, open-minded, and multidisciplinary #PhD candidates to research at the intersection of #mitochondria, #metabolism, #imaging & #physiology, with the #Alps as a backdrop. Sounds like you or someone you know? Link below! @fbm-unil.bsky.social @unil.bsky.social

15743

Reposted by Paolo De Los Rios

Mathieu M.J.E. Rebeaud @chercheurjuteux.com · 15/04/2026

Dans cette revue écrite avec Pierre et @paolodelosrios.bsky.social nous partons du postulat que les interactions entre Hsp70 et Hsp110 existant dans les eukaryotes peuvent potentiellement déjà exister dans les prokaryotes. Si on regarde plus précisément certains dérivés des Hsp70, il est probable

111

Reposted by Paolo De Los Rios

Melanie Blokesch @mblokesch.bsky.social · 10/04/2026

Excited to share our new paper out today in @science.org 🎉 We show that HGT via natural competence drives diversification of chromosomal integrons in V. cholerae 🤩 Below a 🧵 on key findings incl. background on natural competence in V. cholerae 1/ #microsky #phagesky www.science.org/doi/10.1126/...

science.org

1322689

Paolo De Los Rios @paolodelosrios.bsky.social · 21/03/2026

Postdoc opening with us at EPFL! Experimental project on how ATP driven chaperone cycles keep proteins out of equilibrium. We will quantify energy use, kinetics, and functional outcomes, including clients whose native-like functional state is stable only by sustained chaperone action.

2811

Reposted by Paolo De Los Rios

IMPRS for Living Matter @imprs-lm.bsky.social · 18/03/2026

Interested in uncovering how the #Golgi reacts to stress? Apply NOW to the @hellerschmiedlab.bsky.social @imprs-lm.bsky.social #chembio #cellbio #biochemistry

043

Paolo De Los Rios @paolodelosrios.bsky.social · 19/03/2026

I subscribe each and every statement here. What I am just afraid of is that it might not work. Say that we were able to replace all present oil consumption by other (preferably renewable) sources. Oil would still be there to be used, ON TOP OF the renewables, ... 1/2

120

Reposted by Paolo De Los Rios

Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 16/03/2026

We are hiring a postdoc in computational biophysics and machine learning studies of intrinsically disordered proteins We aim to study the function of IDPs by combining CG MD, ML and bioinformatics in collaboration with @tanjamittag.bsky.social & @rhp-lab.bsky.social tinyurl.com/REWIRE-PD

Postdoc position:Computational Biophysics of Disordered Proteins, Lindorff-Larsen group, University of Copenhagen, Denmark

https://tinyurl.com/REWIRE-PD
Deadline May 3rd, 2026

07142

Paolo De Los Rios @paolodelosrios.bsky.social · 14/03/2026

You can't miss it. It is one in a lifetime meeting! (technically, it is one every third year, but each of them is one in a lifetime). See you there!

000

Reposted by Paolo De Los Rios

EPFL Library @epfllibrary.bsky.social · 24/02/2026

🗃️ EPFL adheres to the F.A.I.R. data principles, advocating for the proper management of data and code. In this course, you will gain a foundational understanding of Research Data Management, and explore the EPFL services that can better meet your needs. Register here: bookwhen.com/fr/epfl_libr...

023

Paolo De Los Rios @paolodelosrios.bsky.social · 20/02/2026

Here it is! Thanks to @fcaredda.bsky.social (who did the heavy lifting) , @lgennai.bsky.social and Andrea Pagnani. It has been a really fun collaboration. journals.plos.org/ploscompbiol...

051

Reposted by Paolo De Los Rios

Suliana Manley @sulianamanley.bsky.social · 19/02/2026

Thanks for highlighting our work on combining AI-based organelle dynamics detection in phase contrast with fluorescence! www.nature.com/ncomms/edito... @natcomms.nature.com and Nelio Rodriguez. Spearheaded by @wl-stepp.bsky.social with collaborators @jclandoni.bsky.social @maweigert.bsky.social

02911

Paolo De Los Rios @paolodelosrios.bsky.social · 16/02/2026

... and here it is. If you must produce TDP-43 in a P2 lab (as it is increasingly the case as it is recognised as dangerous), take a look at what Subhasis and Satyam have come up with. Any further feedback is most welcome. www.sciencedirect.com/science/arti...

sciencedirect.com

Refolding-assisted purification of native full-length TDP-43 compatible with BSL-2 safety regulations

TAR DNA-binding protein 43 (TDP-43) is a prion-like RNA-binding protein that plays a key role in amyotrophic lateral sclerosis and frontotemporal deme…

061

Reposted by Paolo De Los Rios

David Balchin @davidbalchin.bsky.social · 13/02/2026

Join us at the @crick.ac.uk for the 2026 meeting of the UK proteostasis community! We especially encourage students and postdocs to attend and share their work. All talks (except the keynotes) will be selected from abstracts.

02115

Reposted by Paolo De Los Rios

MPI for Multidisciplinary Sciences @mpi-nat.bsky.social · 04/02/2026

📣 Our department @compbiophys.bsky.social is hiring a PhD Student or Postdoc in the field of theory and methods for non-equilibrium theory and atomistic simulations of complex biomolecules. Check out our website for the possible projects & further information: ⬇️ www.mpinat.mpg.de/5199181/01-26

075

Reposted by Paolo De Los Rios

Mathieu M.J.E. Rebeaud @chercheurjuteux.com · 21/01/2026

Distribution and evolutionary significance of the DnaK–DnaJ–GrpE (KJE) chaperone system in Archaea The paper is already here in its pre-proof form! I'll do a small thread on it a bit later. Really happy to share it. www.sciencedirect.com/science/arti...

sciencedirect.com

Distribution and evolutionary significance of the DnaK–DnaJ–GrpE (KJE) chaperone system in Archaea

A prevailing hypothesis for the emergence of life on Earth holds that it might have originated in hydrothermal vents, where the environmental conditio…

32710

Paolo De Los Rios @paolodelosrios.bsky.social · 18/01/2026

Meloni : "riprendere il dialogo ed evitare una escalation" Se parla di escalation militare e/o economica con gli USA, forse Meloni dovrebbe porsi delle domande

000

Reposted by Paolo De Los Rios

Cristian Farias @cristianfarias.com · 03/01/2026

Best thing I’ve read this morning, from a human rights lawyer in Mexico. Translation is in the ALT-text.

Twitter thread in Spanish by José Mario de la Garza, a human rights lawyer in Mexico, translated using Google Translate:

1. Overthrowing a dictator sounds morally right. No one mourns a tyrant. But international law wasn't built to protect the good, but to restrain the powerful. That's why it prohibits force almost without exception: not because it ignores injustice, but because it knows that if each country decides whom to "liberate" by force, the world reverts to the law of the strongest.

2. The problem is not Maduro. The problem is the precedent. When military force is used to change governments without clear rules, sovereignty ceases to be a limit and becomes an obstacle. Today it is “overthrowing a dictator”; tomorrow it will be “correcting an election,” “protecting interests,” “restoring order.” The law does not absolve dictatorships, but neither does it legitimize unilateral crusades.

Cont’d:

3. The uncomfortable question is not whether a tyrant deserves to fall, but who decides when and how. Because history teaches something brutal: removing a dictator is easy; building justice afterward is not. And when legality is broken in the name of good, what almost always follows is not freedom, but chaos, violence, and new victims. The law exists to remind us of this, even when it makes us uncomfortable.

Maduro isn't the problem: he's the face of the problem. Removing him from power would be merely opening the door. Behind him is the machine: Rodríguez, Cabello, the military command, the operators of repression and plunder. If you only change the person at the top and leave the system intact, what follows isn't democracy: it's a reshuffling.

And there's something even more difficult: Chavismo didn't just capture institutions, it captured daily life. Economy, media, bureaucracy, employment, fear, favors, blackmail. A country can't be "de-Chavistaized" by decree or by an electoral miracle. The real transition begins when that network is broken without setting the country ablaze.

The challenge is enormous, and it's also a moral one: to unite without vengeance, but without impunity. Targeted justice for those most responsible, truth for the victims, guarantees that the rest will dismantle the system, and a plan for people to live again—not just survive. Because freedom doesn't come with a new president: it comes when the state ceases to be a threat.

3927971346

Reposted by Paolo De Los Rios

Just Jack @just-jack-1.bsky.social · 04/01/2026

With this regime anything is possible…

28095382358

Paolo De Los Rios @paolodelosrios.bsky.social · 19/12/2025

The sun behind the mountains, their shadows on the clouds, their reflections on the lake

030

Paolo De Los Rios @paolodelosrios.bsky.social · 15/12/2025

Cool work by Satyam and Subhasis! They show how to purify native-like TDP-43 while respecting all the safety rules that could limit the kind of instruments and procedures that can be used. A lot of small gems hidden in it, by the way. www.biorxiv.org/content/10.6...

biorxiv.org

Native, full-length, refolding-assisted purification of TDP-43 compatible with BSL-2 safety regulations

TAR DNA-binding protein 43 (TDP-43) is a prion-like RNA-binding protein that plays a key role in amyotrophic lateral sclerosis and frontotemporal dementia. Producing full-length TDP-43 consistently is...

051