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Lisa Gennai

@lgennai.bsky.social

225 followers 729 following 6 posts

PhD at EPFL | Biophysics and Machine Learning

Lisa Gennai @lgennai.bsky.social · 12/05/2026

Our new preprint is out! With @fcaredda.bsky.social, @chercheurjuteux.com , Andrea Pagnani and @paolodelosrios.bsky.social, we introduce CLAPP to predict interactions between paralogs www.biorxiv.org/content/10.6...

biorxiv.org

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Reposted by Lisa Gennai

Mathieu M.J.E. Rebeaud @chercheurjuteux.com · 12/05/2026

Partner determination from protein sequences using class information with CLAPP New preprint alert! Here @lgennai.bsky.social, @paolodelosrios.bsky.social, and @fcaredda.bsky.social et al. (Including yours truly) worked on this for some time already. www.biorxiv.org/content/10.6...

biorxiv.org

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Reposted by Lisa Gennai

Paolo De Los Rios @paolodelosrios.bsky.social · 21/03/2026

Postdoc opening with us at EPFL! Experimental project on how ATP driven chaperone cycles keep proteins out of equilibrium. We will quantify energy use, kinetics, and functional outcomes, including clients whose native-like functional state is stable only by sustained chaperone action.

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Paolo De Los Rios @paolodelosrios.bsky.social · 20/02/2026

Here it is! Thanks to @fcaredda.bsky.social (who did the heavy lifting) , @lgennai.bsky.social and Andrea Pagnani. It has been a really fun collaboration. journals.plos.org/ploscompbiol...

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Paolo De Los Rios @paolodelosrios.bsky.social · 22/08/2025

Here we are, trying to teach an old, but always fantastic dog (Direct Coupling Analysis) some new tricks! It learns them pretty well. Together with @fcaredda.bsky.social @lgennai.bsky.social and bluesky-absent Andrea Pagnani. www.biorxiv.org/content/10.1...

biorxiv.org

Controllable Protein Design via Autoregressive Direct Coupling Analysis Conditioned on Principal Components

We present FeatureDCA, a statistical framework for protein sequence modeling and generation that extends Direct Coupling Analysis (DCA) with biologically meaningful conditioning. The method can levera...

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