Fluctuation-driven feedback allows eukaryotic gene silencing to selectively suppress harmful genetic elements, with aberrant transcription reinforcing silencing locally while modulating it globally.

TLDR: A massive study of 300+ million lab tests from 1+ million women just proved what women have been saying for years: menopause isn't a gradual slope—it's a physiological cliff. Nearly e

The authors present a computational framework that leverages mechanical force inference and spatial transcriptomics to enable analyses of the interplay between the transcriptomic and mechanical state.

The behavior of nonlinear systems near critical transitions has significant implications for stability, transients, and resilience in complex systems. Transient times, $\ensuremath{\tau}$, become extr...

We analyze a generalization of Modern Hopfield networks that emerges naturally in the gene regulatory networks that control cellular identity. Here gene expression patterns correspond to stored memori...

Engineering Turing patterns has been one of the most challenging problems in synthetic biology because even tiny changes in the reaction parameters destroy patterning. Here, the authors construct a more robust three-node genetic circuit in E. coli to generate different kinds of reproducible spot and stripe patterns.

Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...

CFP | Lifelong Development | Development | The Company of Biologists Special Issue – Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues Development invites yo...

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