iiinova — where your digital self keeps evolving

Reposted by Oliver Stegle

Brian Clarke @brianfclarke.bsky.social · 29/07/2026

Our division is recruiting a PhD student through the Helmholtz Information and Data Science School for Health (HIDSS4Health). The supervision will be joint between me, @oliverstegle.bsky.social and @junyanlu.bsky.social. www.hidss4health.de/application/ → Project ID03 Deadline August 18

hidss4health.de

Application - Helmholtz Information & Data Science Academy

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Oliver Stegle @oliverstegle.bsky.social · 31/03/2026

Great opportunity! Bridge academia & industry. Join us on AI in genetics. Also for AI people with no (little) biology exposure.

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Oliver Stegle @oliverstegle.bsky.social · 10/02/2026

Thank you. Looking forward, also to learn more about the HMC approach to metadata!

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Danai Vagiaki @danaivagiaki.bsky.social · 08/02/2026

Delighted to present Latent Interaction Variational Inference (LIVI), a framework for trans-eQTL mapping at single-cell resolution that I developed during my PhD together with colleagues from @steglelab.bsky.social 1/n

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Reposted by Oliver Stegle

Stegle Lab @steglelab.bsky.social · 07/01/2026

Fresh off the press in 2026! Interested in the challenge of how to advance from descriptive atlases to causal mechanisms and counterfactuals? 🔬 Take a look at our recent perspective: "Interpretation, extrapolation and perturbation of single cells"! (rdcu.be/eXeDY)

rdcu.be

Interpretation, extrapolation and perturbation of single cells

Nature Reviews Genetics - Causal and mechanistic modelling strategies, which aim to infer cause–effect relationships, provide insights into cellular responses to perturbations. The authors...

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Reposted by Oliver Stegle

Britta Velten @brittavelten.bsky.social · 03/12/2025

With @leopoldparts.bsky.social and @oliverstegle.bsky.social we comprehensively mapped CRISPRi responses in iPSCs identifying protein complexes as nexus for transcriptional changes and made a first step towards population-scale CRISPR screens to dissect genetic modulation of perturbation responses

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Oliver Stegle @oliverstegle.bsky.social · 08/11/2025

I'm impressed by how far this model class has taken us—MOFA-FLEX may be the final iteration—a framework geared more towards generating models than being a standalone model itself. User-friendly, probabilistic programming rocks! We look forward to your feedback and experiences trying it out!

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Reposted by Oliver Stegle

Ewan Birney @ewanbirney.bsky.social · 08/09/2025

Are you an AI expert who wants to stay in academia and change the world by understanding the most complex things we know - living organisms? Want to lead your own group, based in Heidelberg DE, working language English? @embl.org is hiring in AI embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

embl.wd103.myworkdayjobs.com

Group Leader – AI in Biology

Are you ready to lead groundbreaking research in AI for Biology? Join us at EMBL! We are seeking a visionary scientist to establish their own independent research group bridging innovations in machine...

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Reposted by Oliver Stegle

Ewan Birney @ewanbirney.bsky.social · 08/09/2025

If you want more information please contact @oliverstegle.bsky.social who is leading AI @ EMBL and please do forward this thread / websites to anyone who you think might be interested.

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Oliver Stegle @oliverstegle.bsky.social · 28/08/2025

You are passionate about making data accessible? The Heidelberg Mannheim life science builds a data space - a major step for bridging basic science and translation. Two of more jobs to come. Technical lead and cloud engineer jobs.dkfz.de/en/jobs/1680... jobs.dkfz.de/en/jobs/1680...

jobs.dkfz.de

Technical Lead for the "Health + Life Science Alliance Data Space"

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Oliver Stegle @oliverstegle.bsky.social · 26/06/2025

Job alert: Join us for a postdoc in AI in genetics at @EMBL Heidelberg! Great collaboration with @Adrian Cortes @GSK, aiming to develop new tools to elucidate genetic effects using population-scale cohorts and single-cell readouts. Please share! embl.wd103.myworkdayjobs.com/de-DE/EMBL/d...

embl.wd103.myworkdayjobs.com

Postdoctoral Researcher in Computational Genetics

The research group of Oliver Stegle looks for a postdoctoral researcher to join a collaborative project with GSK with the goal to apply computational methods to investigate the effects of rare variant...

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Reposted by Oliver Stegle

European Research Council (ERC) @erc.europa.eu · 19/05/2025

Are you based in the U.S. 🇺🇸 or Canada 🇨🇦 and thinking of doing research in Europe? ERC grants offer up to €4.5 million to support groundbreaking, investigator-driven frontier research in all fields. Watch the dedicated info session for researchers in your region👉 youtu.be/92QYink1Lik #ChooseEurope

youtu.be

ERC Grants: EU funding for your bottom-up research proposal (2025)

YouTube video by EURAXESS North America

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Oliver Stegle @oliverstegle.bsky.social · 19/05/2025

Super happy and proud of this one. We and others have developed tools for dimensionality reduction for many years. MOFA (linear) and other non-linear generalisations, space/time. scDORI fuses this with GRN inference. It’s a nice and useful piece of software. Here applied to GBM biology.

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Oliver Stegle @oliverstegle.bsky.social · 19/05/2025

Happy birthday! What a trajectory in just 3y. More exciting tools & packages and of course community.

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Reposted by Oliver Stegle

Eric Topol @erictopol.bsky.social · 18/05/2025

This week's genome editing triumph is a big deal. Here's why erictopol.substack.com/p/the-first-...

Multiple headlines about the first CRISPR 2.0 personalized genome editing and photo of the baby treated

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Reposted by Oliver Stegle

Deutsches Krebsforschungszentrum (DKFZ) @dkfz.bsky.social · 07/05/2025

The next #ScienceatDKFZ event will take place on Monday, 12 May 2025, at 4 pm. In addition to the keynote lecture by Christoph Plass, there will be four 5-minute short talks by DKFZ junior scientists on recent highlight publications. ➡️ dkfz.de/en/news/even...

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Reposted by Oliver Stegle

ELLIS Unit Heidelberg @ellisheidelberg.bsky.social · 30/04/2025

Our unit is connecting @dkfz.bsky.social, @uniheidelberg.bsky.social & @embl.org - @oliverstegle.bsky.social, @lena-maier-hein.bsky.social, @wkhuber.bsky.social, @brittavelten.bsky.social, Anna Kreshuk, Carsten Rother, Fred Hamprecht, Jan Korbel, Ullrich Köthe, Klaus Maier-Hein, Tilman Plehn, ...

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Reposted by Oliver Stegle

Karsten Rippe @karsten-rippe.bsky.social · 31/03/2025

“We all rely on science.” U.S. scientists are speaking out for scientific integrity and academic freedom. What they’re doing matters. We owe them our solidarity and a clear stand beside them. www.nytimes.com/2025/03/31/s...

nytimes.com

Trump Administration Has Begun a War on Science, Researchers Say (Gift Article)

Nearly 2,000 scientists urged that Congress restore funding to federal agencies decimated by recent cuts.

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Oliver Stegle @oliverstegle.bsky.social · 27/03/2025

Reverse brain drain? But yes, science in Europe is great!

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Reposted by Oliver Stegle

EMBL @embl.org · 26/03/2025

Are you a young researcher and want to access state-of-the-art technology? The Corporate Partnership Programme is your chance! 💥 CPP cover: 💡 opportunity to build new networks 💰 short-term fellows up to 4.000€ 🌍 eligible to stay at EMBL sites Apply until 31 March: www.embl.org/about/info/s...

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Reposted by Oliver Stegle

Health + Life Science Alliance Heidelberg Mannheim @hlsalliance.bsky.social · 26/03/2025

Interview von Wolfgang Wick mit der Deutschen Welle zum Thema "Brain Drain" von Wissenschaflter*innen in den USA als Chance für Deutschland. Dieses Video ist nur auf deutsch erhältlich. youtu.be/0GtZ_lfL8Rc?...

youtu.be

Wie Europa von Trumps Krieg gegen die Wissenschaft profitieren könnte | DW Nachrichten

YouTube video by DW Deutsch

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Reposted by Oliver Stegle

Wolfgang Huber @wkhuber.bsky.social · 19/03/2025

Interested in doing a sabbatical at EMBL, at one of its 6 sites in Barcelona, Cambridge, Grenoble, Hamburg, Heidelberg or Rome? Funding call with deadline 15 June, decisions in July. www.embl.org/about/info/s...

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Reposted by Oliver Stegle

EMBL-EBI @ebi.embl.org · 19/03/2025

We’re thrilled to announce that the EMBL-EBI Thornton Building has been officially opened by Lord Vallance of Balham, the UK’s Minister for Science, Research and Innovation. We hope it will be a space where collaboration, translation, and science can thrive! 🌱

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Oliver Stegle @oliverstegle.bsky.social · 19/03/2025

I could not really motivate myself to start properly on Bluesky following my departure from twitter. Maybe this picture is a good place to start. Antwerpen central station. What a building m!! Looking forward to www.vibconferences.be/events/revol...

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Oliver Stegle @oliverstegle.bsky.social · 19/03/2025

Really great collab with @moritzgerstung.bsky.social and Dana Pe’er lab. Excited to hear what you all think. Cell segmentation is just hard… more to Come! Will also show a bit of it tomorrow at www.vibconferences.be/events/revol....

vibconferences.be

Revolutionizing Next-Generation Sequencing (6th edition)

19-21 March 2025, Antwerp, Belgium A VIB Tools and Technologies conference

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Oliver Stegle @oliverstegle.bsky.social · 12/03/2024

Next up: Melissa Sanabria on LLMs for genomic data. What is the best vocabulary to tokenise DNA sequences? #EESAIBio.

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Oliver Stegle @oliverstegle.bsky.social · 12/03/2024

New Symposium on AI and Biology starting now! #EMBL #EESAIBio. www.embl.org/about/info/c...

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