Nature Reviews Immunology, Published online: 22 April 2026; doi:10.1038/s41577-026-01294-2This Review discusses the diverse lymphocyte responses that occur against Leishmania parasites. In particular, the authors highlight how these immune responses contribute to the disease spectrum seen in humans following infection with Leishmania.

Colonic stem cells retain a memory of inflammation following disease resolution and there is a mechanistic link between chronic inflammation and malignancy, suggesting potential strategies to mitigate...

Cytotoxicity-associated genes exhibit heterogeneity at the cellular and tissue levels (left). NKG7 gene expression is strongly associated with a cytotoxic gene signature (middle). NKG7 expression is ...

Nature - Data from 300,000 births reveal how essential biological measurements are altered by carrying and delivering a baby.

Jennifer Rohn delights in the discovery-laden memoir of palaeobiologist Hope Jahren's life scientific.

Resting human CD56Dim natural killer cells utilize exogenous pyruvate to support energy metabolism. A new study shows that these cells take up exogenous pyruvate, which regenerates cytosolic NAD+ via ...

An immunologist and his illustrator friend reveal tips and tricks to help scientists to reach peak performance and creativity.

SciDraw - an open repository of science drawings

Multimodal single-cell RNA sequencing identified a population of CD8+ T cells elevated in tumor tissue enriched for interferon-stimulated genes (ISG). These ISG cells are clonally related to a popula...