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Nicolas Di-Poi

@nicolasdipoi.bsky.social
2.8K followers 2.5K following 10 posts

Ecological and Evolutionary Developmental Biologist on craniofacial tissues in reptile models 🐍🦎🐢🐊 Research Director @helsinki-biotech.bsky.social (www.helsinki.fi/en/researchgroups/v…)

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Nicolas Di-Poi @nicolasdipoi.bsky.social · 22/09/2026
Our collaborative paper on snake coiling is now out in the latest issue of @currentbiology.bsky.social and featured on the cover! 🎉 Delighted to see our work highlighted this way. You can read it here: authors.elsevier.com/c/1ni9h3QW8S... @helsinki-biotech.bsky.social @helsinki.fi
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Science Magazine @science.org · 01/09/2026
Unlike the embryos of other vertebrates, early snake embryos coil as they get longer, typically forming clockwise spirals. A new study offers an explanation for why embryonic snakes go through these contortions—and why they tend to curve in one direction. Learn more: scim.ag/4ygkAQk
Snake embryos often coil in one direction. Now, we may know why
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Nicolas Di-Poi @nicolasdipoi.bsky.social · 31/08/2026
And with a nice coverage of our study in Science @science.org ! 🐍🌀 More on the developmental mechanics behind snake coiling here: doi.org/10.1126/scie...
doi.org
Snake embryos often coil in one direction. Now, we may know why
Mismatch between growth of body and digestive system bends the body, study suggests
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Nicolas Di-Poi @nicolasdipoi.bsky.social · 31/08/2026
Ever wondered why snake embryos coil?🐍 A beautifully simple question with a fascinating answer: a growth mismatch between body & gut shapes the coil Our study from @helsinki-biotech.bsky.social @helsinki.fi with T. Miyashita & R.E. Diaz in @currentbiology.bsky.social www.cell.com/current-biol...
cell.com
How snake embryos coil
Snake embryos coil, but how and why they corkscrew remains unexplored. Weber et al. find that the embryos wind up clockwise via buckling of the rapidly elongating axial body against the slow-growing, ...
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Science X / Phys.org @sciencex.bsky.social · 09/08/2026
Around 80 million years ago, early snakes were already living underground, on land and at sea. Fossils suggest they evolved along multiple ecological paths, not just one. doi.org/hcd7vm
phys.org
Early snakes explored life underground, on land and at sea
Snakes are highly modified lizards, with more than 4,000 living species today. The origin of snakes has long been one of evolutionary biology's most debated questions.
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University of Helsinki @helsinki.fi · 04/08/2026
An exceptionally preserved fossil from Brazil from around 80 million years ago shows that the first snakes tried out several different habitats early in their evolution. 🐍 Our researchers led the 3D rendering of the fossil and the comparative analysis of its brain anatomy.
helsinki.fi
Early snakes explored life underground, on land and at sea | HiLIFE – Helsinki Institute of Life Science | University of Helsinki
Snake origins were more dynamic than expected. An exceptionally preserved fossil from Brazil shows that the first snakes tried out several different habitats early in their evolution. Researchers at the University of Helsinki led the 3D rendering of the fossil and the comparative analysis of its brain anatomy.
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Brandon Moore, PhD @rando.insalubrio.us · 03/08/2026
An exceptionally preserved Cretaceous snake fossil, Tametara mirim, reveals evidence of a burrowing lifestyle. Other early snakes inhabited different environments (in water, etc.), showing that snake evolution affected habitat much earlier than previously thought! 🧪 www.nature.com/articles/s41...
Life reconstruction of the burrowing stem snake Tametara mirim against a background of sauropod dinosaurs and the enantiornithean bird Navaornis from the same locality in the Adamantina Formation, Late Cretaceous of Brazil. 

Credit: Gabriel Ugueto
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MU-Peter Shimon 🀄 @mu-peter.bsky.social · 03/08/2026
Exceptional brain and ecological diversity in the earliest snakes🧪 www.nature.com/articles/s41... Cretaceous fossil snake, Tametara mirim gen. et sp. nov. Major ecological transitions occurred early in snake evolution, and known stem species do not represent the ancestral condition of crown snakes
Holotype (MPM 420) of T. mirim.Early snake evolutionary tree depicting placement of T. mirim and major changes in snake brain structure.
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MU-Peter Shimon 🀄 @mu-peter.bsky.social · 03/08/2026
🐍 Snakes We have studied them for a long time, and one of the oldest questions about them is: What turned snakes into snakes? 80‑million‑year‑old snake fossil sheds light on why lizards lost their limbs and started slithering 🧪 theconversation.com/80-million-y...
The new fossil of Tametara mirim reframes how we understand snake evolution. Agustin Martinelli
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Nature Portfolio @natureportfolio.nature.com · 31/07/2026
A newly identified snake species found in Brazil may be the earliest-known snake to have diverged from the stem line, according to research in Nature. go.nature.com/44JIwyI #Paleosly 🧪
Tametara mirim life reconstruction 

Life reconstruction of the burrowing stem snake Tametara mirim against a background of sauropod dinosaurs and the enantiornithean bird Navaornis from the same locality in the Adamantina Formation, Late Cretaceous of Brazil.  

Credit: Gabriel Ugueto
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Nature @nature.com · 29/07/2026
Nature research paper: Exceptional brain and ecological diversity in the earliest snakes go.nature.com/3Rquu24
go.nature.com
Exceptional brain and ecological diversity in the earliest snakes - Nature
A well-preserved fossil snake from the Late Cretaceous of Brazil shows early ecological and brain shape disparity in the group.
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Gabriel Ugueto @serpenillus.bsky.social · 24/07/2026
Congrats to Tiago Simôes and colleagues for this amazing publication. I am really happy that Tiago and his team entrusted me to reconstruct this amazing taxon. Here is a link to the paper in Nature: www.nature.com/articles/s41...
nature.com
Exceptional brain and ecological diversity in the earliest snakes - Nature
A well-preserved fossil snake from the Late Cretaceous of Brazil shows early ecological and brain shape disparity in the group.
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Ferwen @ferwen.bsky.social · 23/07/2026
Exceptional brain and ecological diversity in the earliest snakes www.nature.com/articles/s41...
nature.com
Exceptional brain and ecological diversity in the earliest snakes - Nature
A well-preserved fossil snake from the Late Cretaceous of Brazil shows early ecological and brain shape disparity in the group.
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scienceartnews.bsky.social @scienceartnews.bsky.social · 23/07/2026
trsimoes.bsky.social emphasize that the origin of snakes was not shaped by a single ecological path, but by parallel and overlapping experiments with a burrowing lifestyle and other lifestyles. nature.com/articles/s41586-026-10809-9 2/2
nature.com
Exceptional brain and ecological diversity in the earliest snakes - Nature
A well-preserved fossil snake from the Late Cretaceous of Brazil shows early ecological and brain shape disparity in the group.
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dactylioceras.bsky.social @dactylioceras.bsky.social · 22/07/2026
Exceptional brain and ecological diversity in the earliest snakes Tametara mirim gen. et sp. nov. Art @serpenillus.bsky.social www.nature.com/articles/s41...
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Climate, Ecology, War & More: Dr. Glen Barry BigEarthData.ai @bigearthdata.ai · 22/07/2026
Exceptional brain and ecological diversity in the earliest snakes ->Nature | More on "Ancient snake brain ecological diversity" at BigEarthData.ai | #Ecological
nature.com
Exceptional brain and ecological diversity in the earliest snakes
Micro-CT scanning and digital reconstruction of T. mirim The holotype MPM 420 of T. mirim was scanned in the Laboratório de Caracterização Tecnológica of the Escola Politécnica at the University of São Paulo using a Zeiss Xradia Versa XRM-510 Scanner. The specimen was scanned in three parts: one for the skull and anteriormost cervicals, the second one focusing on posterior cervical vertebrae, and the third one on dorsal vertebrae. Parameters were as follows for all scans: 110 kV, 10 W, 25-s exposure (skull and cervicals) or 8 s (dorsals), and a 0.4× objective with HE6 filter resulting in 1,301 images. Voxel sizes were as follows: skull = 17.19 µm, cervicals = 16.2 µm and dorsals = 34 µm. Reconstruction was made with the software Xradia. Reconstruction and the parameters included a beam hardening of 0.08 and a smooth filter with a 0.5 kernel size. Segmentations of osteological structures, cranial endocasts and inner ear were performed using VGSTUDIO MAX v3.5., and 3D cinematic renderings were produced using the SmARTR pipeline36. Morphological and molecular phylogenetic data Here we used the last iteration41 of the total evidence dataset originally published by Simões et al.5, to assess the placement of Tametara not only among...
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Gabriela Sobral @sobralg.bsky.social · 22/07/2026
I hope you enjoy our paper and that fossil snake ecology and evolution can be approached in new and exciting ways from now on! Again, if you haven't yet, read the full story here: www.nature.com/articles/s41...
nature.com
Exceptional brain and ecological diversity in the earliest snakes - Nature
A well-preserved fossil snake from the Late Cretaceous of Brazil shows early ecological and brain shape disparity in the group.
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Francesca Cesari @francesari.bsky.social · 23/07/2026
An exceptionally preserved fossil snake from the Late Cretaceous of Brazil, likely to have been a burrower, illuminates early ecological disparity in the group.🧪👇 www.nature.com/articles/s41...
nature.com
Exceptional brain and ecological diversity in the earliest snakes - Nature
A well-preserved fossil snake from the Late Cretaceous of Brazil shows early ecological and brain shape disparity in the group.
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Marcos K. Pinheiro / "Marcos Wyvern" (Marcosaurus) @mmarcosaurus.bsky.social · 22/07/2026
www.nature.com/articles/s41...
nature.com
Exceptional brain and ecological diversity in the earliest snakes - Nature
A well-preserved fossil snake from the Late Cretaceous of Brazil shows early ecological and brain shape disparity in the group.
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パンテオン @dinopantheon.bsky.social · 22/07/2026
ブラジル、サンパウロ州、バウル盆地、白亜紀後期の地層から産出した幹系統ヘビ Tametara mirim 属名:先住民トゥピ・グアラニー語で、目立つ矢状稜から、装飾された 種小名:同じく、小さい マイクロCTスキャンにより、その脳神経や内耳の構造を3Dで精密に再現→現生の穴掘り性ヘビに極めて近い、地下生活に特化した感覚機能を持っていた →当時の初期ヘビは既に地下、地上、海へ進出し、多様な生き方を試していた ヘビの進化の初期段階で大きな生態学的転換が起こり、既知の祖先種が現生ヘビの祖先状態を表しているわけではないことを示す 論文OA www.nature.com/articles/s41...
nature.com
Exceptional brain and ecological diversity in the earliest snakes - Nature
A well-preserved fossil snake from the Late Cretaceous of Brazil shows early ecological and brain shape disparity in the group.
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Claude ✡️🦖🦕 @cascoclauda.bsky.social · 22/07/2026
here is the #openaccess study describing tametara www.nature.com/articles/s41...
nature.com
Exceptional brain and ecological diversity in the earliest snakes - Nature
A well-preserved fossil snake from the Late Cretaceous of Brazil shows early ecological and brain shape disparity in the group.
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Nature Portfolio @natureportfolio.nature.com · 23/07/2026
A newly identified snake species found in Brazil may be the earliest-known snake to have diverged from the stem line, according to research in Nature. go.nature.com/44JIwyI #Paleosly 🧪
Tametara mirim life reconstruction 

Life reconstruction of the burrowing stem snake Tametara mirim against a background of sauropod dinosaurs and the enantiornithean bird Navaornis from the same locality in the Adamantina Formation, Late Cretaceous of Brazil.  

Credit: Gabriel Ugueto
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Henry Gee 亨利·纪 @endofthepier.bsky.social · 22/07/2026
Early-diverging stem snake illuminates early diversity of our serpentine friends. Paper in @nature.com @trsimoes.bsky.social www.nature.com/articles/s41...
nature.com
Exceptional brain and ecological diversity in the earliest snakes - Nature
A well-preserved fossil snake from the Late Cretaceous of Brazil shows early ecological and brain shape disparity in the group.
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Tiago Simões @trsimoes.bsky.social · 22/07/2026
Proud to share our latest paper in out in Nature today on the origin of #snakes. We present Tametara mirim, an articulated 3D preserved stem snake from the Late Cretaceous of Brazil. Tametara helped us re-tell the story of snake origins in a novel way... www.nature.com/articles/s41...
nature.com
Exceptional brain and ecological diversity in the earliest snakes - Nature
A well-preserved fossil snake from the Late Cretaceous of Brazil shows early ecological and brain shape disparity in the group.
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Gabriela Sobral @sobralg.bsky.social · 22/07/2026
Our work is out! Meet Tametara mirim, a new fossil snake 🐍 from Brazil that has challenged our views on early snake evolution! A jewel 💎 from the Cretaceous brought to you by an amazing team of colleagues among which @trsimoes.bsky.social and @nicolasdipoi.bsky.social! www.nature.com/articles/s41...
nature.com
Exceptional brain and ecological diversity in the earliest snakes - Nature
A well-preserved fossil snake from the Late Cretaceous of Brazil shows early ecological and brain shape disparity in the group.
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Nicolas Di-Poi @nicolasdipoi.bsky.social · 22/07/2026
🎥 Also, check out our video abstract highlighting the main findings: youtu.be/_Csv11XnhoU
youtu.be
The Queen of Snakes: Tametara and the Dawn of Snake Evolution
YouTube video by Di-Poï Evo-Devo LAB Helsinki
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Nicolas Di-Poi @nicolasdipoi.bsky.social · 22/07/2026
Excited to see our work with @trsimoes.bsky.social and @anniehsiou.bsky.social published in Nature @nature.com 🐍 Early snake evolution was more dynamic than expected, spanning diverse habitats and sensory strategies 🐍 @helsinki-biotech.bsky.social @helsinki.fi www.nature.com/articles/s41...
nature.com
Exceptional brain and ecological diversity in the earliest snakes - Nature
A well-preserved fossil snake from the Late Cretaceous of Brazil shows early ecological and brain shape disparity in the group.
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bioRxiv Developmental Biology @biorxiv-devbio.bsky.social · 12/03/2026
An alternative patterning mechanism for vertebrate tooth complexity www.biorxiv.org/content/10.64898/20…
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Ryan N. Felice @rnf.bsky.social · 21/12/2024
turns out you can do some pretty cool stuff with the power of diceCT, SPROUT (www.biorxiv.org/content/10.1...), and the SmARTR pipeline (www.sciencedirect.com/science/arti...)
a 3d rendering of the skull and cranial muscles of the Eurasian oystercatcher (Haematopus ostralegus)
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Nicolas Di-Poi @nicolasdipoi.bsky.social · 10/12/2024
Any publicly accessible scans can be used. Stained scans such as diceCT are needed for visualizing soft tissues. Segmentation of the tissues of interest is required before rendering (see steps 4-5 of our pipeline). We are happy to provide assistance or advice if needed during the process.
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Nicolas Di-Poi @nicolasdipoi.bsky.social · 10/12/2024
Thanks 😊
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Nicolas Di-Poi @nicolasdipoi.bsky.social · 09/12/2024
New snake renderings from CT scan data, created using our recently published SmARTR photorealistic pipeline! 🐍 Our manuscript is now in its final published form: doi.org/10.1016/j.is...
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Nicolas Di-Poi @nicolasdipoi.bsky.social · 02/12/2024
Excited to regularly share squamate renderings created with our recently published SmARTR photorealistic pipeline—all derived from solely CT scan data! Check out the networks to create your own also here: github.com/MeVisLab/SmA...
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Nicolas Di-Poi @nicolasdipoi.bsky.social · 23/11/2024
Do you use 3D imaging like CT or MRI for research, teaching, outreach, or art? Check out our new article featuring a detailed workflow for producing 3D cinematic renderings―from tissue-level to whole-organism details―with stunning realism! doi.org/10.1016/j.is... @helsinkiuni.bsky.social
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