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Nicky McGranahan

@nickymcgranahan.bsky.social

162 followers 175 following 1 posts

Professor of Cancer Evolution. UCL Cancer Institute. Interested in cancer genomics, bioinformatics, and somatic evolution. www.ucl.ac.uk/medical-sciences/divi…

Posts Replies Media

Reposted by Nicky McGranahan

Chris Tape @christophertape.bsky.social · 31/10/2025

Paul Nurse describing the main job of a PI (From ‘The Thinking Game’, 2024)

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Nicky McGranahan @nickymcgranahan.bsky.social · 13/10/2025

I wanted my first @bsky.app post to be witty, thoughtful & somewhat self-depreciating. I wanted to make sure I could highlight all the exciting computational cancer evolution research my lab does, without sounding too arrogant. But, instead I posted this. (At least it's within the character limit.)

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Reposted by Nicky McGranahan

Eugene Valkov @eugenevalkov.bsky.social · 29/07/2025

An excellent systematic analysis of RBPs by @quaidmorris.bsky.social and colleagues (with a tiny contribution from us) #RNAsky #RNAbiology

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Reposted by Nicky McGranahan

Trevor Graham @trevorgraham.bsky.social · 10/09/2025

Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...

nature.com

Fluctuating DNA methylation tracks cancer evolution at clinical scale - Nature

Cancer evolutionary dynamics are quantitatively inferred using a method, EVOFLUx, applied to fluctuating DNA methylation.

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Reposted by Nicky McGranahan

Ferriol Calvet @ferriol.bsky.social · 08/10/2025

Very excited to share our new paper on the influence of biological sex and smoking in the clonal landscape of normal human bladder, just published in Nature. A big thank you and congrats to all the authors, specially to @raquelbmi.bsky.social for all the shared efforts in this journey! ⬇️More info⬇️

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Reposted by Nicky McGranahan

Waggoner Lab @labwaggoner.bsky.social · 13/08/2025

Clone copy number diversity is linked to survival in lung cancer @nature.com @zaccasimo.bsky.social @nickymcgranahan.bsky.social www.nature.com/articles/s41...

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