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Mark Lambie

@mlambie.bsky.social
864 followers 357 following 3 posts

Nephrologist, especially dialysis, especially at home, and clinical studies about these things

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Reposted by Mark Lambie
kireports.bsky.social @kireports.bsky.social · 18/12/2025
New RCTs Advance #Incremental #Dialysis With Clinically-Guided HD and HDF-Based Prescriptions doi.org/10.1016/j.ekir.2025.10.002 Original Article: doi.org/10.1016/j.ekir.2025.09.048 doi.org/10.1016/j.ekir.2025.08.043 #KIRCommentary
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Reposted by Mark Lambie
Saloni @scientificdiscovery.dev · 28/12/2025
New post! There was a lot of innovation in medicine and biomedical research this year, and I've tried to summarize the biggest ones in this blogpost. Medical breakthroughs in 2025. Plus a serious note at the end. www.scientificdiscovery.dev/p/medical-br...
scientificdiscovery.dev
Medical breakthroughs in 2025
... and a happy new year.
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Eric Goffin @er-goffin.bsky.social · 17/07/2025
Really interesting ; this study emphasises the influence of genetic variants to explain the great inter-individual variability of ultrafiltration in Peritoneal Dialysis patients even at PD onset together with the emerging role of peritoneal adipocytes and prostaglandins in peritoneal physiology 👏👏👏
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Mark Lambie @mlambie.bsky.social · 17/07/2025
journals.lww.com/jasn/abstrac... Great work led by @rajmehrotra.bsky.social substantially improving our understanding of UF in PD
journals.lww.com
Genetic Variation and Ultrafiltration with Peritoneal... : Journal of the American Society of Nephrology
tration and explored one mechanistic pathway identified by genetic studies. Methods: We generated estimates of heritability and undertook genome-wide and gene-wise studies, adjusted for peritoneal ...
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Reposted by Mark Lambie
Johann Morelle @johannmorelle.bsky.social · 31/01/2025
Will Xylocore® be the magic ELIXIR for peritoneal dialysis? @ispd.org @pdi-journal.bsky.social @drnikhilshah.bsky.social @pd-perls.bsky.social @mlambie.bsky.social Editorial: journals.sagepub.com/eprint/ENYAN... Original article: journals.sagepub.com/doi/10.1177/...
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UK Kidney Association @ukkidney.org · 07/01/2025
Upcoming highlights in Advanced Kidney Care... ✅ AKC Symposium 2025 27 February, London bit.ly/3ZTMXFt ✅ AKC Summit 2025 25 March, Birmingham bit.ly/49GOl1v ✅ Transform AKC Programme www.ukkidney.org/about-us/new...
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Reposted by Mark Lambie
Niakhaleen Keita NephroGalsen @niakhaleenkeita.bsky.social · 15/01/2025
💥Conakry PD Workshop Insert PD catheter to manage AKI complications is crucial where indications are not lacking. Training to save (young) lives is essential @sosendt.bsky.social @er-goffin.bsky.social @ispd1.bsky.social @theisn.org @sfndt.bsky.social
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Reposted by Mark Lambie
Kidney Care UK @kidneycareuk.bsky.social · 18/12/2024
The National Institute for Health and Care Excellence has recommended a new treatment called Vadadustat as an option for treating anaemia caused by chronic kidney disease in adults on dialysis. You can find out more about this here: kidneycareuk.org/news-from-ki...
kidneycareuk.org
New treatment recommended for anaemia in adults on dialysis
The National Institute for Health and Care Excellence have recommended a new treatment called Vadadustat as an option for treating anaemia caused by chronic kidney disease in adults on dialysis.
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Reposted by Mark Lambie
BK. Titanji @boghuma.bsky.social · 12/12/2024
Wow just wow. I did not have on my bingo card an mRNA therapeutic for treating pre eclampsia. A VEGF tropic mRNA resolved maternal hypertension until pregnancy in a mouse model of the condition. Really fascinating science. 🧪 www.nature.com/articles/s41...
nature.com
Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia - Nature
A platform for mRNA lipid nanoparticle delivery to the placenta to treat pre-eclampsia is shown to improve fetal and maternal health in mice and has potential clinical applications in obstetric d...
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Florian Buchkremer @swissnephro.bsky.social · 08/12/2024
1/5 The #SWEETSTONE results were presented at the Swiss Society of Nephrology meeting: Impact of #empagliflozin on urinary supersaturations in kidney stone formers. Randomised, double-blind, placebo-controlled, cross-over trial. #nephsky #nephrolithiasis #flozinator
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William Bonnaud Dowell @bonnaud-dowell.bsky.social · 29/11/2024
I guess this answers the question : pubmed.ncbi.nlm.nih.gov/27890698/
pubmed.ncbi.nlm.nih.gov
Clementine juice has the potential for drug interactions - In vitro comparison with grapefruit and mandarin juice - PubMed
Adverse drug interactions due to grapefruit juice are well known prompting warnings even in drug labels. Similar issues have not been reported for clementines and available data is scarce, despite of ...
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Sunil Badve @sunilbadve.bsky.social · 26/11/2024
Sharing the free access link here (for 50 days only) authors.elsevier.com/a/1k9u77tNuc...
authors.elsevier.com
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kireports.bsky.social @kireports.bsky.social · 25/11/2024
1/ Hello, #NephSky! Excited to share a 🆕 #Skeetorial on Automated Peritoneal Dialysis (APD) as a modality for Urgent Start Dialysis! Brought to you by the fantastic team at @kireports.bsky.social Let's dive in! #skeetorial
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ISPD - International Society for Peritoneal Dialysis @ispd.org · 25/11/2024
We just added to www.ispd.org/guidelines the German translation for our ISPD 2022 Peritonitis Guidelines. We thank Dr V. Schwenger for making these important guidelines available beyond language barriers. Wanna help us translate ISPD guidelines? Please DM us for more info.
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Dr Martha Gulati @drmarthagulati.bsky.social · 16/11/2024
@TheLancet session at #AHA24 starting now! #obesity 🫀Malnutrition was a problem but now obesity is taking over worldwide with few exceptions 🫀Severe obesity has also ⤴️ 🫀BMI doesn’t reflect obesity as well as waist-to-height ratio 🫀⤴️ diabetes follows obesity
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Eric Topol @erictopol.bsky.social · 14/11/2024
We've already seen remarkable results for lupus and other autoimmune diseases with CD19 B cell depletion therapy. Now add IgG4 related disease (which has no treatment) in a new randomized trial nejm.org/doi/full/10....
nejm.org
Inebilizumab for Treatment of IgG4-Related Disease | NEJM
IgG4-related disease is a multiorgan, relapsing, fibroinflammatory, immune-mediated disorder with no approved therapy. Inebilizumab targets and depletes CD19+ B cells and may be effective for treat...
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Parham Eshtehardi MD @cardioobdoc.bsky.social · 14/11/2024
#Tirzepatide for Obesity Treatment & Diabetes Prevention SURMOUNT-1 Trial ✅ Reduced progression to T2DM by 93% #CardioSky #EndoSky #MedSky #NEJM www.nejm.org/doi/full/10....
nejm.org
Tirzepatide for Obesity Treatment and Diabetes Prevention | NEJM
Obesity is chronic disease and causal precursor to myriad other conditions, including type 2 diabetes. In an earlier analysis of the SURMOUNT-1 trial, tirzepatide was shown to provide substantial a...
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