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Heather Brown-Harding

@microscopyed.bsky.social
2.1K followers 1.2K following 660 posts

Light Microscopy Manager at Brandeis University. I help people do cool science. Lover of all things microscopy & microbiology 🔬🦠

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Heather Brown-Harding @microscopyed.bsky.social · 8h
Congratulations to @marianadeniz.bsky.social for winning the Michael W. Davidson Memorial Award! 🎉 #I2KxBINA
Mariana at the podium in front of her presentation titled "Sticks in a bundle are unbreakable"
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Heather Brown-Harding @microscopyed.bsky.social · 11h
One of this morning's talks is @kevin-dean.bsky.social explaining how to do cyclic IF for ExM #I2KxBINA
Kevin at a podium with slide titled "Post-Expansion Cyclic Immunofluorescence"
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Heather Brown-Harding @microscopyed.bsky.social · 30/09/2026
Awesome session with @emiglietta.bsky.social on 'gamification' of co-localization analysis. It did a great job making folks think about the whole acquisition to analysis pipeline.
Esteban standing in front of screens saying "The CoLoc Game."
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Heather Brown-Harding @microscopyed.bsky.social · 29/09/2026
QuPath workshop with Michael Nelson-- going through many new extensions! #I2KxBINA
Michael sitting at the podium with a segmented image on the screen
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Heather Brown-Harding @microscopyed.bsky.social · 29/09/2026
I made it to #I2KxBINA 2026! First keynote by @saramcardle.bsky.social on using QuPath on to study pancreatic tissue sections with multiple staining rounds!
Sara presenting her work with a slide about T1D disrupting islets
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Heather Brown-Harding @microscopyed.bsky.social · 28/09/2026
This is not a drill, there is a plane for me to get on! I might actually make it to BINA in Madison this time
American airlines plan at the gate in Logan airport
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Heather Brown-Harding @microscopyed.bsky.social · 28/09/2026
Ok, not reply department email, but it reminds me of the time several people got vacuum sealed mice in orders of plastic wear (that the did not order). Ahh, the good times of SciTwitter
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Heather Brown-Harding @microscopyed.bsky.social · 28/09/2026
Ok, fingers crossed I get out today so I can get to @bioimagingna.bsky.social!
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Heather Brown-Harding @microscopyed.bsky.social · 27/09/2026
And it's cancelled 😕
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Heather Brown-Harding @microscopyed.bsky.social · 25/09/2026
Nothing like waiting for maintenance to come on a Friday evening because the autoclave next door is leaking into the scope room...
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Richard Sever @richardsever.bsky.social · 24/09/2026
Interesting article from Henning & Ivan prompted by departures at Genentech. As they say the "question is not whether scientists should embrace AI [but] how AI should reshape the role of scientists". Like many, they worry that in a rush to embrace AI some orgs aren't being smart enough...
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Heather Brown-Harding @microscopyed.bsky.social · 24/09/2026
Hopefully, my flight gets out for @bioimagingna.bsky.social 😬 weather.com/2026/09/24/f...
weather.com
Nor'easter bringing impacts from NC to New England
Coastal flooding and gusty winds are already affecting parts of the mid-Atlantic as the powerful nor'easter slides up the East Coast into this weekend.
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Heather Brown-Harding @microscopyed.bsky.social · 23/09/2026
Anyone have any seen red autofluorescence in the agarose pad while imaging c. elegans
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Heather Brown-Harding @microscopyed.bsky.social · 23/09/2026
Next week I'm at @bioimagingna.bsky.social x I2K in Madison, Wisconsin. When I need a break from sessions, what should I check out?
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Jenna Norton @jenna-m-norton.bsky.social · 23/09/2026
What. A. Day. NIH grant-making was paused for several hours today. Not sure who gave the order. But in light of the Friday night Bhattacharya-Vought feud & threatened EO to implement #ScienceDeathPanels, my money is on Russell Vought. I learned of the pause from a colleague around 11:30. 🧵
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MadScientist @mads100tist.bsky.social · 23/09/2026
"embrace slop to create things that do not exist from a sample that was probably donated by some kid with the premise of studying their disease" Conflating AI and genAI on purpose is loser behavior and Nikon Small World will always have that label to me 🧪
A screencap from the interview where the researcher says"

His advice to other researchers considering entering the competition is straightforward: “Take care of the sample, use as little light as possible when working with living cells, and embrace AI to reveal the hidden beauty in your data. Most importantly, keep recording. The best moment usually appears right after you decide to stop.”
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Heather Brown-Harding @microscopyed.bsky.social · 21/09/2026
My Spinn coffee maker has died 🥺 The one I want is nearly $2k😬 What's the best one for people that want a delicious coffee, but doesn't want to faff about in the morning? www.terrakaffe.com/products/tk-...
terrakaffe.com
Terra Kaffe TK-02 - Best Fully Automatic Espresso Machine
Get $200 Off now with a coffee subscription. TK-02 is the most advanced super automatic espresso machine from Terra Kaffe. Smart technology with the included app makes for a truly seamless and connect...
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BioImaging North America @bioimagingna.bsky.social · 18/09/2026
Can’t join us in Madison? You can still be part of I2KxBINA 2026 virtually via Zoom Events! - Virtual registration is FREE! buff.ly/qoZqTbm - Virtual registration closes September 27, 2026
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MadScientist @mads100tist.bsky.social · 17/09/2026
You know what's also interactive? Reading the paper. Talk to your colleagues about the paper you just read. Tell them why you loved it. Tell them why you hated it. And even better: invite the authors to talk about their paper 🧪
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Heather Brown-Harding @microscopyed.bsky.social · 16/09/2026
I had a dream that I came into work and the lightsheet was filled with tater tots. How's your morning going? 🤣
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Heather Brown-Harding @microscopyed.bsky.social · 11/09/2026
I may have planted too many things for the 7th year in a row. 😬 I don't have it in me to process another 4 quarts of beans this week, so neighbors will be getting care packages
Bench with 2 containers of tomatoes, a container and a bag of beans, a spaghetti squash and a zucchini
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Heather Brown-Harding @microscopyed.bsky.social · 10/09/2026
I'm quite busy right now and I'm trying to finish up a poster for #BINA. I wanted an updated list of Comms WG Members. Please see the glory of Gemini. #1
Image of comms group with 2 Heathers, 2 Hiphys, & an  Eduardo with Hiphy's image
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Florian Wollweber @florianwollweber.bsky.social · 05/09/2026
Exciting news! Our @erc.europa.eu StG project ARCHAEAOLOGY got funded 🎉 We’ll combine cryoET/EM, ExM & spatial omics to explore the subcellular organization of Asgard archaea. Job ads coming soon! 🦠 ❄️ 🔬 #TeamTomo #ArchaeaSky #MicroSky
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Heather Brown-Harding @microscopyed.bsky.social · 04/09/2026
Last week, @whipkclark.bsky.social visited Brandeis to meet with the @turrigiano.bsky.social lab. She stopped by the light microscopy core, where we showed her what the support of the state and federal grants can achieve.
Picture of me standing in a microscope suite with Rep. Katherine Clark. You can see a STED image in green and red on the computer screen of a neuron
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Erin Fogg says Free Link @criminalerin.bsky.social · 30/08/2026
"The zoo was in Durham County on Aug. 16 and Aug. 23 for separate private events. The zoo also made stops in Statesville, Lexington, Watauga County, Burke County and Mocksville between July 28 and Aug. 27. In Lexington, the zoo was part of a back-to-school bash." RABID! GOATS! AT! SCHOOL!
wral.com
4 rabid goats linked to traveling petting zoo that visited Durham County
Health officials are warning of a possible rabies exposure after four goats from a traveling petting zoo tested positive following stops in Durham County and several other North Carolina communities.
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Marco Dalla Vecchia @marcodv.bsky.social · 27/08/2026
Interested in image analysis and a service role in a dynamic and growing facility? Come and joy our image analysis team! Feel free to reach out for any questions or doubts. ista.ac.at/en/job/?titl...
ista.ac.at
Job details
Job details
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MapQuest @mapquest.com · 27/08/2026
We’re not changing it.
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Heather Brown-Harding @microscopyed.bsky.social · 26/08/2026
Acquired a new sticker today 🎉
Black note book with a sticker that says "I'm not a bug. I'm a feature." With a caterpillar on it
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Heather Brown-Harding @microscopyed.bsky.social · 26/08/2026
Ahh, so we are repeating 2020
static.klipy.com
Théoden: So It Begins
Alt: Théoden: So It Begins
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Heather Brown-Harding @microscopyed.bsky.social · 26/08/2026
And this is why I emphasized how important running antibody controls during a pilot experiment (and every new lot) was if you didn't want to waste time and money on data that turned out un-usable
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Avital Rodal @rodallab.bsky.social · 25/08/2026
Our first manuscript from the wonderful Dr. Anne Silveira's thesis work!
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Reese Richardson @reeserichardson.bsky.social · 25/08/2026
A massive update: At least ~15 companies~ are selling scientists antibodies using faked validation data. We've documented 18,000+ manipulated images on 17,000+ products sold by leading laboratory suppliers including Thermo Fisher, Abcam, Santa Cruz Biotechnology, Millipore Sigma and Bio-Techne. 1/🧵
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Rolling Stone @rollingstone.com · 25/08/2026
Dolly Parton's family asked that, in lieu of flowers, fans make a donation to the singer's Imagination Library. Here's what the charity does ⬇️ www.rollingstone.com/music/music-...
rollingstone.com
Turning Pages: Inside Dolly Parton's Imagination Library
Core team of 15 staff and thousands of volunteers and partners help the country-music philanthropist deliver books to kids around the world.
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Heather Brown-Harding @microscopyed.bsky.social · 21/08/2026
Folks, it was a parking miracle! My spot was still there. Now if the microscope gods wanted to allow micro-manager to communicate to ALC and a 6 laser sled...
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Heather Brown-Harding @microscopyed.bsky.social · 21/08/2026
I got to work at 7:30 so I could get through things before there were more requests. I haven't taken more than 5 minutes for lunch all week, so I think I'll treat myself to Five Guys. But I also don't want to give up my clutch parking spot I got so early. #FirstWorldProblems
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Heather Brown-Harding @microscopyed.bsky.social · 21/08/2026
I got to work at 7:30 so I could get through things before there were more requests. I haven't taken more than 5 minutes for lunch all week, so I think I'll treat myself to Five Guys. But I also don't want to give up my clutch parking spot I got so early. #FirstWorldProblems
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Image Cooperative @image.coop · 19/08/2026
Our next office hours session is coming up in just under 22h! 2026-08-20 at 9am Paris/12:30pm Delhi/5pm Melbourne. Ask us anything about OME-Zarr and/or watch @jni.codes attempt to live-release the experimental 0.9dev1 version (including RFCs 3 & 4) with @joshmoore.bsky.social's help!
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Heilemann Lab @heilemannlab.bsky.social · 17/08/2026
🚨 2x PhD opportunities: single-molecule/super-resolution microscopy & image analysis of membrane proteins 🔬(DM for details) 👉🏻 tinyurl.com/5dt7ncby 👉🏻 tinyurl.com/5e52dth2 🙏 Dear colleagues & friends, pls distribute - Thank you! 🙏 @crc1507.bsky.social imol.uni-frankfurt.de @goetheuni.bsky.social
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Jenna Norton @jenna-m-norton.bsky.social · 14/08/2026
Of course this RFI drops late on Friday. NIH proposes to stop providing specific scores and instead bin grants into 3 broad categories: most competitive, competitive, not discussed. A score would be calculated but not provided to the PI (or PO). grants.nih.gov/grants/guide...
grants.nih.gov
NOT-OD-26-088: Request for Information (RFI) on Proposed Changes to Reporting Outcomes from NIH Peer Review
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information (RFI) on Proposed Changes to Reporting Outcomes from NIH Peer Review NOT-OD-26-088. NIH
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Richard Sever @richardsever.bsky.social · 13/08/2026
bioRxiv/medRxiv have been dealing with endless bot attacks recently (plus usual DDOS stuff, etc). Tricky to address without impacting genuine users - many of you affected. Apologies. We're working with our hosting service on solutions & think we're getting there [he shouts in his Red Queen costume].
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voigtvision.bsky.social @voigtvision.bsky.social · 12/08/2026
🚨 Now out in @aaas.org Science Advances 🚨: aDISCO: a protocol for clearing & antibody-staining human formalin-fixed paraffin-embedded (FFPE) tissue by Anna Maria Reuss! 🧠🔬#lightsheet #Microscopy @mesospim.bsky.social @ptrrupprecht.bsky.social www.science.org/doi/10.1126/...
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Harvard Brain Science Initiative @harvardbrainsci.bsky.social · 11/08/2026
Nuria Domínguez-Iturza and Paola Arlotta present new research describing the molecular signals that promote myelination in the cerebral cortex and show that these signals are expressed at varying levels across neuronal types. brain.harvard.edu/hbi_news/how...
brain.harvard.edu
How Different Neurons Shape Myelination in the Cerebral Cortex
Nuria Domínguez-Iturza and Paola Arlotta present new research describing the molecular signals that promote myelination in the cerebral cortex and show that these signals are expressed at varying leve...
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Heather Brown-Harding @microscopyed.bsky.social · 12/08/2026
Ask Kesley about her 100s of TBs of lightsheet data 😉
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Kelsey Tyssowski @kelseytea.bsky.social · 11/08/2026
At the 2026 BRAIN Initiative Conference! if you‘re coming and want to meet up, lmk! 🧠
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Heather Brown-Harding @microscopyed.bsky.social · 11/08/2026
So if the session chair and two speakers are the same gender, do I need to worry about this? Like it only becomes a problem if it's 4+, right? How do we feel about this science folks?
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Jeremy Baskin @jeremybaskin.bsky.social · 06/08/2026
Thrilled to share our new work, co-developed w/Adrian Salic's lab: bioorthogonal probes for labeling PE, a multifunctional membrane lipid and source of important protein modifications. Congrats to Yuan-Ting Cho, Brittany White-Mathieu, Jade Xia, & Cindy Jao! onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Bioorthogonal Tools for Ethanolamine Lipids and Protein Conjugates
An alkyne-tagged ethanolamine analog (AlkEA) enables bioorthogonal, metabolic labeling of endogenous phosphatidylethanolamine (PE) and its protein modifications. AlkEA is incorporated into PE via the...
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Cédric Moisy @cedric-moisy.bsky.social · 07/08/2026
2/3 – 🌱 Nature doesn't have a pause button... Fortunately, Fijiyama does the next best thing: it aligns 3D scans over time so scientists can follow the same tissues as plants grow. 👀 A time-lapse — in 3D. 🔬🌱🍇 🔗 doi.org/10.1093/bioi... 🔗 doi.org/10.1016/j.pl... #Science #Time #Fiji #3D #SMIYC
infographic showing how Fijiyama tracks plant growth over time. Four aligned 3D reconstructions of the same grapevine tissue are displayed along a timeline from day 0 to day 105. Perfect registration allows scientists to compare the exact same structures as the plant develops.
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Heather Brown-Harding @microscopyed.bsky.social · 07/08/2026
LinkedIn keeps emailing me that I should apply for my old job. I mean, sure the skills match impressively well, but their algorithm can't figure out that it is in fact the same job? 😝
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Juan C. Landoni @jclandoni.bsky.social · 05/08/2026
Collecting recent-ish papers for a Cell Bio 101 course I'm teaching this fall. Ideally microscopy-driven breakthroughs that are also experimentally elegant and well written. Any favourites I should check out? 🔬
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Heather Brown-Harding @microscopyed.bsky.social · 03/08/2026
First day of managing my very own core. Let's do this @brandeisuniversity.bsky.social !
Heather points at a sign on a door that says "Brandeis Imaging Research Community Hub"
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