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Fralin Biomedical Research Institute

@fralinbiomed.bsky.social
91 followers 20 following 109 posts

Advancing Health Through Science 🧠🔬🧬🫀 fbri.vtc.vt.edu

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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 14/09/2026
How do we know when cancer treatment works? Come to the Maury Strauss Distinguished Public Lecture on Thursday, Sept. 17, “Why Measure?” news.vt.edu/articles/202...
news.vt.edu
How do we know when cancer treatment works?
Physician-scientist Christopher Hourigan will open the Maury Strauss Distinguished Public Lecture season in Roanoke with insights into precision medicine and the search for residual leukemia.
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 31/08/2026
No more trial and error Psychiatry is moving toward a future in which treatment can be informed by the biology of the individual patient. fbri.vtc.vt.edu/events/speci...
fbri.vtc.vt.edu
Precision Therapeutics for Schizophrenia Symposium
Sept. 23-24, 2026 | Fralin Biomedical Research Institute at VTC | 4 Riverside Circle, Roanoke, Virginia
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 31/08/2026
Scientists, clinicians, and pharmaceutical leaders are gathering at Virginia Tech to consider whether psychiatry can move beyond trial-and-error treatment. The inaugural Precision Psychiatry Symposium will examine how. news.vt.edu/articles/202...
news.vt.edu
Beyond trial and error: A more precise approach to psychiatry
The Fralin Biomedical Research Institute will convene leaders in neuroscience, clinical research, and drug development to Roanoke to examine advances that could enable more individualized care for sch...
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Chris Smith @drchristsmith.bsky.social · 01/07/2026
The Mishra Lab @fralinbiomed.bsky.social seeks a #postdoc to work on AHA-funded research projects focused on cardiometabolic disease, heart failure w/ preserved ejection fraction, mitochondrial biology, cardiac remodeling, & cardiovascular physiology. Apply by 7/6! jobs.apply.vt.edu/jobs/postdoc...
jobs.apply.vt.edu
Postdoctoral Associate - Roanoke, Virginia, United States
Job Description The Fralin Biomedical Research Institute at VTC in Roanoke, VA, is dedicated to the promotion of health and the prevention and treatment of lifestyle-related disease. The Mishra Labo...
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Meike van der Heijden @meikeesther.bsky.social · 26/06/2026
Very proud of Viviana Hernández-Castañón, postdoc in my lab, for receiving a @dystoniafoundation.bsky.social fellowship. She studies how brain signals evolve in dystonia, a debilitating movement disorder. @fralinbiomed.bsky.social @vtneuroscience.bsky.social news.vt.edu/articles/202...
news.vt.edu
Predicting the onset of a debilitating neurological disorder
Viviana Hernández-Castañón, a postdoctoral associate at the Fralin Biomedical Research Institute at VTC, will use a fellowship from the Dystonia Medical Research Foundation to investigate brain activi...
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Meike van der Heijden @meikeesther.bsky.social · 17/06/2026
New Preprint: Competitive Olivocerebellar Input Selection Promotes Resilient Circuit Formation -- Join the ride for some developmental neuroscience, stay for some pretty pictures. doi.org/10.64898/202...
doi.org
Competitive Olivocerebellar Input Selection Promotes Resilient Circuit Formation
Many neural circuits undergo competitive input selection, a process in which supernumerary connections compete for innervation territory on target cells. This process can create atypical circuits when...
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 17/06/2026
Researchers at @virginiatech.bsky.social and @utah.edu identified a protein called PERM1 that may help explain why some patients recover heart function after advanced heart failure treatment. See what PERM1 could reveal about heart recovery ❤️‍🩹 news.vt.edu/articles/202...
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 12/06/2026
Ataxia affects balance, coordination, and mobility. 🧠 @virginiatech.bsky.social researcher Alyssa Lyon is studying whether targeted brain stimulation can improve symptoms by restoring neural communication. See how this work out of @meikeesther.bsky.social's lab could advance ataxia treatment 👇
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 09/06/2026
What’s the most effective way to reduce tobacco use? 🚬 New @virginiatech.bsky.social research examined menthol restrictions, flavor bans, and tobacco taxes, while also tracking how the industry adapts to regulation. Find out more 👇 news.vt.edu/articles/202...
news.vt.edu
‘The right patchwork’: New studies examine tobacco regulation
Three studies led by addiction researcher Roberta Freitas-Lemos examine approaches to reducing tobacco use, including tax policies and menthol bans.
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Alex DiFeliceantonio @difeliceantonio.bsky.social · 04/06/2026
New paper out in @amjpublichealth.bsky.social! We used machine learning to identify nutritional charecteristics of foods with addictive potential as rated from a national sample. @fralinbiomed.bsky.social This was a big collaborative effort! 1/7 🧪 ajph.aphapublications.org/doi/suppl/10...
ajph.aphapublications.org
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 02/06/2026
Samar Antar received an @americanheart.bsky.social Career Development Award to study how connexin 43 drives pulmonary fibrosis. 🫁🔬 The goal: identify therapeutic targets that could move beyond slowing disease and help reverse lung damage. @virginiatech.bsky.social
Samar Antar, a postdoctoral associate with the Fralin Biomedical Research Institute at VTC in Roanoke, received a Career Development Award from the American Heart Association to support her research into much-needed therapies for pulmonary fibrosis. Photo by Clayton Metz for Virginia Tech.
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The Journal of Physiology @jphysiol.bsky.social · 25/05/2026
In this recent study, Alyssa M Lyon from @fralinbiomed.bsky.social and colleagues found that steady-state #Purkinje cell activity has limited predictive power for #cerebellar output in disease 🧠 🔎 Read the research 👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 20/05/2026
Researchers at @virginiatech.bsky.social identified a potential new strategy for treating idiopathic pulmonary fibrosis by blocking two proteins linked to lung scarring. 🫁 Preclinical models showed reduced fibrosis and improved lung function. news.vt.edu/articles/202...
news.vt.edu
Blocking two proteins reverses lung scarring in preclinical study
Researchers identified a new therapeutic strategy for idiopathic pulmonary fibrosis, that could move beyond delaying the disease to reversing lung scarring.
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 14/05/2026
🎉🎉🎉
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Shannon Farris @shannonfarris.bsky.social · 08/05/2026
Two recently minted PhD students from my lab were recognized by their program for their impactful contributions to science and education. Congrats @mikels-mitos.bsky.social and Renesa! @fralinbiomed.bsky.social
Four pictures of smiling graduate students being recognized for contributions to education, community, leadership, and science.
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Meike van der Heijden @meikeesther.bsky.social · 21/04/2026
🚨 new paper alert 🚨 Anatomical connectivity does not always predict functional connectivity in disease — a cautionary tale from the cerebellum Steady-state Purkinje cell activity has limited predictive power for cerebellar output in disease 1/
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Virginia Tech @virginiatech.bsky.social · 20/04/2026
Michael Halassa, a professor with @fralinbiomed.bsky.social, is integrating neural circuit experiments with computational tools to better measure and treat mental illness. 👏 🔗: brnw.ch/21x1L1G
brnw.ch
Systems neuroscientist takes a new approach to uncover neural drivers of mental illness
A professor with the Fralin Biomedical Research Institute, Michael Halassa is exploring intricate connections in the brain at the new Virginia Tech Patient Research Center at VTC, where he will conduc...
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 17/04/2026
Even in remission, a few hidden #leukemia cells can remain and drive relapse. @virginiatech.bsky.social researcher @jessetettero.bsky.social is developing DNA tools to detect them earlier and improve relapse prediction. 🧬🔬 See how this could reshape cancer care: news.vt.edu/articles/202...
Clinician-researcher Jesse Tettero studies measurable residual disease in acute myeloid leukemia at the Fralin Biomedical Research Institute’s Cancer Research Center in Washington, D.C. Photo by Lena Ayuk for Virginia Tech.
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Alex DiFeliceantonio @difeliceantonio.bsky.social · 13/04/2026
New preprint from the lab🧵🧪 Eating ultraprocessed foods leads to poor health outcomes, but HOW they do it isn't understood. "HOW?" is important, as "how" can allow targeted policy, reformulaiton, or recommendations to reduce harmful effects. We started to ask that question doi.org/10.64898/202...
doi.org
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 06/04/2026
Can sound waves treat chronic pain? 🔊 A @virginiatech.bsky.social researcher is advancing low-intensity focused ultrasound to target deep brain circuits noninvasively, with personalized fMRI-guided therapy. Explore how this could transform pain treatment 👇 news.vt.edu/articles/202...
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Virginia Tech @virginiatech.bsky.social · 27/03/2026
Xuansong Mao of @fralinbiomed.bsky.social will use a Lyerly Postdoctoral Excellence Award to research the role of exercise in Alzheimer’s, metabolic conditions, and age-related cognitive decline. 🔗: brnw.ch/21x16Lv
A photo of Xuansong Mao in a lab. Text reads "Understanding how cells adapt after exercise."
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 27/03/2026
Early, high-dose therapy can significantly improve arm and hand function in infants with cerebral palsy 🧠 A @virginiatech.bsky.social-led trial found multiple therapy approaches are equally effective, giving families evidence-based options. 📰 go.vt.edu/champ-bluesky
go.vt.edu
Intensive therapy approaches show benefits for infants and toddlers with cerebral palsy
Filling a long-standing gap in clinical science, multi-institutional researchers led by Virginia Tech find good news when comparing movement therapies.
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Meike van der Heijden @meikeesther.bsky.social · 27/03/2026
🎉 lab’s first data paper 🎉 TL;DR: we found profound changes in vocal calls produced by mice with early-onset dystonia caused by cerebellar dysfunction. Thus, vocal impairments in people with dystonia may, in part, be driven by cerebellar dysfunction. www.frontierspartnerships.org/journals/dys...
frontierspartnerships.org
Frontiers Publishing Partnerships | Assessing vocal changes through spectral analyses of vocalizations in a cerebellar-specific dystonia mouse model
Vocal impairments are a debilitating but understudied feature of several dystonias, including generalized and early-onset genetic forms. Despite growing reco...
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 25/03/2026
Nearly 50 million Americans face substance use disorders, often involving multiple substances. Yet recovery is still defined as full abstinence—an expectation Allison Tegge of @virginiatech.bsky.social says can feel unattainable. 📰 Learn more: go.vt.edu/tegge-substa...
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Alex DiFeliceantonio @difeliceantonio.bsky.social · 10/03/2026
DONNUT Lab at Brain School for Brain Awareness Week! @fralinbiomed.bsky.social
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Virginia Tech @virginiatech.bsky.social · 10/03/2026
A multi-institutional effort led by @fralinbiomed.bsky.social researchers aims to refine relapse prediction by identifying genetic markers in blood samples from patients with a rare blood cancer. 🧬 🔗: go.vt.edu/ummEq
Cancer researchers including senior author Christopher Hourigan (at left) and first author Rasha Al-Ali of Virginia Tech’s Fralin Biomedical Research Institute found that a highly sensitive DNA-based test can help doctors predict which patients with acute myeloid leukemia, or AML, are most likely to relapse.
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 02/03/2026
Can fat fight #diabetes? 🥑 New research from @virginiatech.bsky.social's Sarah Lessard suggests a high-fat #ketogenic diet may help unlock the benefits of #exercise in people with high blood sugar. Listen and subscribe🎙️ fbri.vtc.vt.edu/newsroom/big... Read more 📰 go.vt.edu/lessardketo-...
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Chris Smith @drchristsmith.bsky.social · 11/02/2026
What can honey bee brain chemistry teach us about human learning? Cool work from Dr. Read Montague's Lab @fralinbiomed.bsky.social in collaboration with Dr. Brian Smith at Arizona State University. news.vt.edu/articles/202...
news.vt.edu
What can honey bee brain chemistry teach us about human learning?
A multi-institutional team of researchers led by Virginia Tech’s Fralin Biomedical Research Institute at VTC has for the first time identified specific patterns of brain chemical activity that predict...
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Virginia Tech @virginiatech.bsky.social · 03/02/2026
A fellowship will help support Yunruo 'Trista' Ni’s graduate research at @fralinbiomed.bsky.social as she investigates how low-intensity focused ultrasound can modify brain circuits to treat memory disorders. 🧠 🔗: brnw.ch/21wZCOx
A James R. Carter Sr. Memorial Award is supporting Yunruo “Trista” Ni’s Alzheimer’s research in Assistant Professor Wynn Legon’s lab at the Fralin Biomedical Research Institute at VTC.
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 23/01/2026
Meet doctoral candidate Caleb Mensah, whose research is uncovering how #glioblastoma — one of the most aggressive brain cancers — evades treatment. Supported by a Ray A. Gaskins Fellowship, his work seeks to unlock discoveries that could improve patient survival. More about Caleb in the comments ⤵️
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 15/01/2026
🚨 New episode of Big Science Small Pod 🚨 Listen in as @virginiatech.bsky.social neurobiologist Matthew Weston explains what happens in the brain during seizures and how his lab is researching their genetic roots to help develop new treatments for children. 🎧👇 news.vt.edu/articles/202...
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Biomedical Picture of the Day BPoD @bpodaily.bsky.social · 20/12/2025
Healing of injured blood vessels is driven by gap junction protein connexin 43 at the wound edge 📷 Meghan W. Sedovy et al Scott Johnstone lab @fralinbiomed.bsky.social AJP Heart and Circulatory Physiology ➡️ bpod.org.uk/archive/2025... with @rooph.bsky.social
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 19/12/2025
A study published in eNeuro from @virginiatech.bsky.social scientists, led by @shannonfarris.bsky.social, shows that neurons organize mRNA based on abundance, helping explain how genetic instructions support learning and memory in the 🧠 📰 @sfnjournals.bsky.social 🔗 news.vt.edu/articles/202...
news.vt.edu
Neurons within the brain localize genetic messages using simple rules, study finds
A new eNeuro study from the Fralin Biomedical Research Institute reveals how neurons organize genetic messages that support learning and memory — and what that means for medical conditions.
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Shannon Farris @shannonfarris.bsky.social · 17/12/2025
Happy to share part I of Renesa Tarannum's thesis (my first grad student!) looking at how neuropil localized RNAs are spatially organized in the hippocampus. #Skeetorial #Neuroskyence 🧪 www.eneuro.org/content/12/1...
eneuro.org
Multiplexed smFISH Reveals the Spatial Organization of Neuropil Localized mRNAs Is Linked to Abundance
RNA localization to neuronal axons and dendrites provides spatiotemporal control over gene expression to support synapse function. Neuronal messenger RNAs (mRNAs) localize as ribonucleoprotein particl...
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Shannon Farris @shannonfarris.bsky.social · 17/12/2025
Here is the @fralinbiomed.bsky.social write up in @virginiatech.bsky.social news. news.vt.edu/articles/202...
news.vt.edu
Neurons within the brain localize genetic messages using simple rules, study finds
A new eNeuro study from the Fralin Biomedical Research Institute reveals how neurons organize genetic messages that support learning and memory — and what that means for medical conditions.
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 16/12/2025
What if we could measure infant brain activity during social interaction? 👶🧠 @virginiatech.bsky.social researchers have secured significant support from the NIH to push the boundaries of human #neuroscience using wearable brain-imaging technology. Details ⤵️ news.vt.edu/articles/202...
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 15/12/2025
Jenny Munson has been awarded two new National Institutes of Health grants to advance greater understanding and improved treatment of a deadly brain cancer. 🙌 Full details👇 news.vt.edu/articles/202...
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 10/12/2025
@thelancet.com says 1 in 3 Americans ages 15–24 may meet obesity criteria by 2050. @virginiatech.bsky.social's @davybrenda.bsky.social and @difeliceantonio.bsky.social tested how young adults ate after two weeks on ultra-processed vs. unprocessed diets. Results👇 news.vt.edu/articles/202...
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Virginia Tech @virginiatech.bsky.social · 10/12/2025
#VirginiaTech researchers are developing techniques to study brain activity between parents and their babies, laying the foundation to identify patterns that point to potential risk for disorders. ⬇️
bit.ly
Next-generation neuroscience studies the infant brain in motion
The Human Magnetometry Laboratory at the Fralin Biomedical Research Institute at VTC is developing magnetoencephalography techniques to study brain activity during natural social interactions between parents and their babies.
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 02/12/2025
How does early-life trauma change the brain? 🧠 New research from @virginiatech.bsky.social's Sora Shin reveals a shared biological mechanism linking aggression and self-harm, tied to how the brain processes pain. Learn more 👇 news.vt.edu/articles/202...
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Bruker @brukercorporation.bsky.social · 25/11/2025
At the @fralinbiomed.bsky.social, cancer scientists are redefining what’s possible in preclinical #imaging. Michael Friedlander, PhD, Jenny Munson, PhD, & core manager Maosen Wang, PhD, share their insights. Watch the full video here: youtu.be/16W2Joqun2g?... @virginiatech.bsky.social #Oncology
youtu.be
Pushing the Boundaries of Preclinical Research: Inside The Fralin Biomedical Research Institute, VTC
YouTube video by Bruker
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 24/11/2025
Surgeons perform nearly 600,000 stent and bypass surgeries in the U.S. each year.🫀 The Johnstone lab at @virginiatech.bsky.social found that the protein connexin 43 helps blood vessels heal — a discovery that could lead to smarter recovery therapies. Learn more 👇 news.vt.edu/articles/202...
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Virginia Tech @virginiatech.bsky.social · 24/11/2025
In a new @fralinbiomed.bsky.social study, 18- to 21-year-olds put on to a diet high in ultra-processed foods were more likely to overeat — even when full. ⬇️🔬Learn more.
news.vt.edu
All you can eat: Ultra-processed foods affect young adults differently
In a new study, 18- to 21-year-olds put on to a diet high in ultra-processed foods were more likely to overeat — even when full.
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Alex DiFeliceantonio @difeliceantonio.bsky.social · 18/11/2025
The lab was on Good Morning America! Absolutely surreal. Everyone did so great on the filming day. I work with the best people ever.
Picture of Good Morning America played on a laptop. Alex DiFeliceantonio at Virginia tech. Picture of a laptop playing good morning America. Zach Hutelin in lab coat in metabolic kitchen. Picture of good morning America on a laptop. Mary Fowler drawing blood in metabolic chamber from Darien Sutton.
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 14/11/2025
A weightlifting mouse? 🐭💪 @virginiatech.bsky.social researchers in Zhen Yan's lab created a mouse model to compare resistance vs. endurance. Both helped reduce fat and improve blood sugar, but weightlifting was more effective. 🔗 news.vt.edu/articles/202...
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 23/10/2025
The same drugs used for diabetes and weight loss may also impact alcohol use. 🍷 A pilot study with @virginiatech.bsky.social and @carilionclinic.bsky.social found that GLP-1 drugs such as Ozempic slow alcohol absorption, lessening its impact on the brain. news.vt.edu/articles/202...
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 21/10/2025
“Chemo brain” affects many #cancer survivors, but why? 🧠 A new @virginiatech.bsky.social study suggests post-chemotherapy memory and focus issues may stem from poor lymphatic drainage triggered by cancer drugs. Learn more 👇 news.vt.edu/articles/202...
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 20/10/2025
By combining #nanotechnology and #immunology, @virginiatech.bsky.social's DaeYong Lee and his collaborators are redefining how the immune system can be harnessed to battle cancer 🧫 Learn more ⤵️ news.vt.edu/articles/202...
news.vt.edu
Cancer researchers shape emerging strategies for immunotherapy
Nanotechnology, the research shows, could reprogram the immune system and help overcome tumors’ defenses, addressing the limitations of current immunotherapies, particularly in treating solid tumors.
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Chris Smith @drchristsmith.bsky.social · 17/10/2025
Postdoc position available @fralinbiomed.bsky.social working in the Addiction Recovery Research Center examining long-term trajectories of addiction recovery. Salary at NIH NRSA stipend level along w/ excellent benefits. Apply by Oct 29! careers.pageuppeople.com/968/cw/en-us...
careers.pageuppeople.com
Details | Postdoctoral Associate | Careers | Division of Human Resources | Virginia Tech
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Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 01/10/2025
Glioblastoma is a lethal #brain #cancer. Patients survive ~15 months on average. Here at @virginiatech.bsky.social's Fralin Biomedical Research Institute, Jenny Munson's team has built a tool to spot hidden cancer cells & predict where tumors will grow next. 📰 ⤵️ news.vt.edu/articles/202...
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