iiinova — where your digital self keeps evolving

Reposted by Meera Chand

Pathoplexus @pathoplexus.org · 15/05/2026

1/ 🚀 Pathoplexus now supports Bundibugyo virus (BDBV), a species of Ebolavirus. BDBV has been associated with past outbreaks of Ebola in the DR Congo and Uganda, & a case has been reported today during response to the current Ebola outbreak. pathoplexus.org/ebola-bdbv #ebola #bdbv #ebolaoutbreak

Image of some of the available pathogens on Pathoplexus, with a red rectangle outlining the new tile for Ebola Bundibugyo virus, with 44 sequences.

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Pathoplexus @pathoplexus.org · 09/05/2026

1/ 🚀 Pathoplexus now supports the Andes variant of Hantavirus (ANDV). ANDV is the variant identified in the recent MV Hondius cases, & the Hantavirus variant previously identified as having occasional human-to-human transmission. pathoplexus.org/andv #hantavirus #hondius

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Dr Emma Hodcroft @firefoxx66.bsky.social · 10/05/2026

My ANDV #Hantavirus @nextstrain.org phylogenies now pull directly from @pathoplexus.org to incorporate all seqs I'll continue to improve them, & will keep them updated Change the Tip Labels in the left-hand menu. You can see links to all builds, plus tanglegrams at: nextstrain.org/groups/hodcr...

A phylogenetic tree showing linked sequences from the S and L segment of ANDV virus (Andes Hantavirus)

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Prof Tom Solomon CBE @runningmadprof.bsky.social · 16/03/2026

Great to see the launch of this new #Encephalitis learning collection on BMJ Learning, designed to support doctors, trainees and the wider healthcare workforce with practical, evidence-based education. Well done to everyone involved! www.encephalitis.info/global-training-modules-on-encephalitis/

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Pathoplexus @pathoplexus.org · 12/03/2026

1/ 🦟 Big news: #Pathoplexus now supports Dengue virus & Yellow Fever virus - two arboviruses responsible for over 400 million infections and up to 94,000 deaths per year. Here's what’s new in our latest update 👇🏻 Read the full update: pathoplexus.org/news/2026-03... 📰

A screenshot of the new Pathoplexus homepage showing all viruses now supported, including Dengue and Yellow Fever, which are circled in red

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Dr Emma Hodcroft @firefoxx66.bsky.social · 12/03/2026

If you want to join a team making pathogen sequencing and analysis for public health, surveillance, and research more accessible, more equitable and more ✨awesome✨ - look no further - come join us on this mission at ARTIC! #openscience #opendata #opensource

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Ed Cunningham-Oakes @edcoakes.bsky.social · 16/12/2025

We are recruiting for a number of PhDs in the HPRU in Public Health Genomics, based at @unibirmingham.bsky.social, in collaboration with UKHSA. 🦠🧬 Apply below to work on cutting-edge science and public health priorities! (NB deadline of 9th January / UK only due to funding restrictions) (1/7)

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Adam Kucharski @adamjkucharski.bsky.social · 19/08/2025

Got a number in mind? A new pre-print by @lshtm.bsky.social colleagues surveyed 13,000 participants, and found it's about 9 per day in the current era. It also looks at how social mixing varies with age, ethnicity and social economic status. Link to paper:

medrxiv.org

Post-pandemic social contact patterns in the United Kingdom: the Connect survey

Close-contact and respiratory infectious diseases are spread through social interactions, which were affected by the COVID-19 pandemic and wider demographic and cultural changes. To estimate post-pand...

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NEJM.org @nejm.org · 06/08/2025

Data on treatments for bubonic plague are limited. In this open-label, randomized, controlled trial in Madagascar, ciprofloxacin monotherapy was noninferior to a standard aminoglycoside–ciprofloxacin regimen. Full IMASOY trial results: nej.md/3Ugs0kx #MedSky #IDSky

A figure showing the primary efficacy analyses in the trial populations.

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Reposted by Meera Chand

Respiratory Microbiomes @resp-micro.bsky.social · 21/07/2025

Early notice of NEW Wellcome Conference - AIR 2026: Genomic and Systems Approaches to Respiratory Infection, Microbiomes and Immunity 11th-13th February, sign up below for notifications coursesandconferences.wellcomeconnectingscience.org/our-events/c... It's immunulogy AND it's microbiology 🫁

coursesandconferences.wellcomeconnectingscience.org

Conferences

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Andrew Rambaut (🐏🎀) @arambaut.bsky.social · 15/07/2025

Some great new features and updates from the awesome Pathoplexus project. This is a new open pathogen genome database that can provide access to your sequences under a use-restricted license but also feed directly in to INSDC (EBI, Genbank etc) when you are ready. pathoplexus.org/news/2025-07...

pathoplexus.org

Pathoplexus | Pathoplexus July Update

Pathoplexus is a new, open-source database dedicated to the efficient sharing of human viral pathogen genomic data, fostering global collaboration and public health response.

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NEJM.org @nejm.org · 04/06/2025

A new report describes the genetic epidemiology and antimicrobial-resistance patterns of a surge of cases of 𝘊𝘰𝘳𝘺𝘯𝘦𝘣𝘢𝘤𝘵𝘦𝘳𝘪𝘶𝘮 𝘥𝘪𝘱𝘩𝘵𝘩𝘦𝘳𝘪𝘢𝘦 infection that was identified in migrant populations in Europe. Read the full report: nej.md/3HEF3ZS #MedSky #IDSky

nej.md

Corynebacterium diphtheriae Outbreak in Migrant Populations in Europe | NEJM

A surge of cases of Corynebacterium diphtheriae infection was observed in reception centers for migrants in Europe beginning in the summer of 2022. Most of the cases were cutaneous, although some r...

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Jason Kindrachuk @kindrachukjason.bsky.social · 02/06/2025

Rolling clinical and epi updates for #mpox data from #SierraLeone. Watch for updated versions as additional data becomes available. Heartfelt thanks to our local colleagues in-country led by Dr. Jia Kangbai t.co/D9QosVP1Bq

t.co

https://www.medrxiv.org/content/10.1101/2025.05.30.25328691v1

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Kristian G. Andersen @kgandersen.bsky.social · 27/05/2025

Amazing work from our colleagues in Sierra Leone, Nigeria, and elsewhere, making the first sequences available from the ongoing Mpox epidemic in Sierra Leone. More to come - for now, head over to @pathoplexus.org: pathoplexus.org/seqsets/PP_S...

pathoplexus.org

Pathoplexus | SeqSets

Pathoplexus is a new, open-source database dedicated to the efficient sharing of human viral pathogen genomic data, fostering global collaboration and public health response.

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Andrew Rambaut (🐏🎀) @arambaut.bsky.social · 25/05/2025

A long thread about mpox and the context specific nature of outbreaks prompted by the large outbreak of MPXV Clade IIb happening at the moment in Sierra Leone:

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Theo Sanderson @theo.io · 22/05/2025

Super exciting that we're now up to eight viruses supported on Pathoplexus - with lots of other exciting features in the pipeline too!

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Nick Loman @pathogenomenick.bsky.social · 22/05/2025

Absolutely thrilled to announce the launch of ARTIC2 - a £5.5M 5 year project funded by @wellcometrust.bsky.social to build on the ARTIC approach of low-cost, globally accessible genome sequencing for surveillance of outbreaks, epidemics and endemic diseases: www.birmingham.ac.uk/news/2025/am...

birmingham.ac.uk

Ambitious project to develop low-cost genome sequencing for pathogens known and unknown - University of Birmingham

Project will build on research that helped diagnostic labs to adopt sequencing capacity for COVID-19 and permit characterisation of future infectious threats

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Eurosurveillance journal @eurosurveillance.org · 17/04/2025

Check out our new issue with a study describing and comparing 🦟 Aedes-borne disease (#dengue #chikungunya and #Zika) incidence from 2017-2023, and the surveillance systems and response measures operating in France, Italy and Portugal in 2023 🗞️ bit.ly/EUS3015 #IDSky #EpiSky #MedSky #PublicHealth 🦠

Image showing the table of content of issue 15 in 2025 featuring the following articles:

Surveillance
Increased incidence of human leptospirosis and the effect of temperature and precipitation, the Netherlands, 2005 to 2023

Description and comparison of national surveillance systems and response measures for Aedes-borne diseases in France, Italy and Portugal: a benchmarking study, 2023

Research
Seroprevalence of West Nile virus, Greece, 2020

Prevalence and risk factors for carriage of carbapenem-resistant Acinetobacter baumannii in post-acute care hospitals, Israel, 2021

Letter
Letter to the editor: Statistical methodology critique and alternative approaches in H5Nx avian influenza seroprevalence study among French cats

Authors’ response: Statistical methodology critique and alternative approaches in H5Nx avian influenza seroprevalence study among French cats

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Marion Koopmans @marionkoopmans.bsky.social · 04/04/2025

Mpox Clade I emerged in 2023 in South Kivu and since has spread sustained through direct human to human contact. Controlling this outbreak has turned out to be a major challenge. Through embedded outbreak research coupled with a local capacity building program, we first....

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UK Health Security Agency @ukhsa.bsky.social · 02/04/2025

We need the help of academics, health & policy professionals, and people with lived experience of tuberculosis (TB) to shape our next TB Action Plan. Together we can improve how we prevent, detect, and control TB. 🛡️ 🗓️ Deadline: 2 May 🔗 www.gov.uk/government/n...

Dr Esther Robinson, Head of the TB Unit at UKHSA, said:

"TB is curable and preventable, but the disease remains a serious public health issue in England. While England is still considered a low-incidence country for TB, the rise in cases over recent years means that we are now just below that threshold.

This call for evidence will help us develop an action plan that prioritises the most effective interventions to reverse this trend, focusing particularly on the needs of those most affected."

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Marion Koopmans @marionkoopmans.bsky.social · 26/03/2025

Another arbovirus popping up in our enhanced surveillance pubmed.ncbi.nlm.nih.gov/40133068/ Not too surprising but a first for our country. No human disease noted, but first indication that we may need to start considering it. First step is to understand if this is a one off finding or not

pubmed.ncbi.nlm.nih.gov

Local Circulation of Sindbis Virus in Wild Birds and Horses, the Netherlands, 2021-2022 - PubMed

We report Sindbis virus circulation in the Netherlands based on serologic evidence found in 6 resident wild birds and 3 horses (2021-2022). Tested mosquitoes were molecularly negative, and humans were...

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UK Health Security Agency @ukhsa.bsky.social · 25/03/2025

Today we have published our first annual report on infectious disease trends. 📊 The report brings together all the key data from 2023 to early 2025 and outlines the steps our organisation is taking to tackle these threats. Read the full report 🔗🔽 www.gov.uk/government/p...

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Bloom lab @jbloomlab.bsky.social · 12/03/2025

In study led by @csimonich.bsky.social & Teagan McMahon, we quantify antigenic evolution of RSV F Important because: 1️⃣ RSV top cause of infant hospitalization in USA 2️⃣ New antibodies & vax can prevent hospitalizations 3️⃣ Will virus evolution erode their efficacy? www.biorxiv.org/content/10.1...

biorxiv.org

RSV F evolution escapes some monoclonal antibodies but does not strongly erode neutralization by human polyclonal sera

Vaccines and monoclonal antibodies targeting the respiratory syncytial virus (RSV) fusion protein (F) have recently begun to be widely used to protect infants and high-risk adults. Some other viral pr...

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Tom Peacock @peacockflu.bsky.social · 08/02/2025

Core-funded postdoc position at The Pirbright Institute, Surrey, UK (just outside London), in the group of Professor Ian Brown. Working on H5N1 avian influenza virus evolution and development of cross-reactive vaccines. www.pirbright.ac.uk/careers-and-...

pirbright.ac.uk

Postdoctoral Scientist

The Pirbright Institute delivers world-leading research to understand, predict, detect, and respond to viral disease outbreaks. We study viruses of livestock that are endemic and exotic to the UK, inc...

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Andrew Rambaut (🐏🎀) @arambaut.bsky.social · 03/02/2025

First genome sequence from the Ugandan Ebolavirus outbreak with analysis: virological.org/t/990 and first filovirus genome submitted to Pathoplexus database: pathoplexus.org/seq/PP_0011C.... Great (and rapid) work from the National Health Laboratory, UVRI and partners.

virological.org

Near Real-Time Genomic Characterization of the 2025 Sudan Ebolavirus Outbreak in Uganda’s Index Case: Insights into Evolutionary Origins

Introduction Case History: On January 30, 2025, the Ministry of Health declared an outbreak of Sudan Ebola Virus (SUDV) Disease in Kampala, Uganda, following the death of a healthcare worker at Mula...

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Meera Chand @meerac.bsky.social · 30/01/2025

Great to be able to share this today - looking forward to working with partners all over the country for the next phase

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Jason Kindrachuk @kindrachukjason.bsky.social · 28/01/2025

Please see the risk evaluation guidance docs on Clade Ia and Clade Ib mpox from the WHO Technical Advisory Group on Virus Evolution (www.who.int/groups/techn...) - excellent work from a great group of colleagues www.who.int/groups/techn... #mpox #PHEIC 1/2

lnkd.in

This link will take you to a page that’s not on LinkedIn

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Amy Maxmen, PhD @amymaxmen.bsky.social · 08/01/2025

Since the USDA launched its Bird Flu milk testing strategy in December, 28 states have enrolled, representing nearly 65% of the nation’s milk production. And there's a dashboard. This was a long time coming but an impressive start. www.aphis.usda.gov/livestock-po...

aphis.usda.gov

National Milk Testing Strategy | Animal and Plant Health Inspection Service

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Adam Kucharski @adamjkucharski.bsky.social · 07/01/2025

Suppose a new flu pandemic were to emerge. How quickly could we get going with key epidemiological analysis and modelling? To find out, I went back through the dozens of reports I was involved in for SPI-M for COVID and estimated where we currently stand: epiverse-trace.github.io/posts/covid-...

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Michael Marks @drmichaelmarks.bsky.social · 05/01/2025

Are you London ID trainee post-PhD & interested in an ACL. May be able to create posts in 2025. Opportunities in Syphilis & STIs (UK & Global), Group A Strep (Global), Leishmaniasis & NTDs. If interested get in touch. @gpollara.bsky.social @drneilstone.bsky.social @thushan-desilva.bsky.social

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Pathoplexus @pathoplexus.org · 09/12/2024

Today Pathoplexus announces the inclusion of a new viral pathogen: mpox (previously known as monkeypox). Within the context of the current mpox outbreaks and ongoing health concerns, Pathoplexus aims to support sequence sharing to improve both understanding and response. 1/7

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WHO @who.int · 08/12/2024

Disease outbreak news on undiagnosed disease in #DRCongo bit.ly/3Zpj12M

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Kristian G. Andersen @kgandersen.bsky.social · 06/12/2024

Interesting follow-up on this. We're running automated analyses on H5N1 data on the SRA to look for potentially important mutations in the virus. Following the study 👇, we looked to see if we could find *any* evidence of the HA Q226L mutation. We did. In a mouse from June of this year. Short 🧵

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Duncan MacCannell @drm.bsky.social · 06/12/2024

The Rise of Mpox in a Post-Smallpox World wwwnc.cdc.gov/eid/article/...

wwwnc.cdc.gov

The Rise of Mpox in a Post-Smallpox World

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Caitlin Rivers @cmyeaton.bsky.social · 17/11/2024

What data should be reported to the public during an outbreak? That's the question my colleagues and I set out to answer in a new(ish) preprint. We developed consensus guidelines for situation reports to enable transparency 🧪https://www.medrxiv.org/content/10.1101/2024.10.24.24315886v1

medrxiv.org

Public reporting guidelines for outbreak data: Enabling accountability for effective outbreak response by developing standards for transparency and uniformity

Currently, there are few standards for what essential information about an infectious disease outbreak should be reported to the public and when. The content and timeliness of public reporting (e.g. s...

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Duncan MacCannell @drm.bsky.social · 13/11/2024

Update and typing for British Columbian H5N1 patient. Virus is clade 2.3.4.4b/D.1.1. Genotype is not associated with the ongoing dairy cattle outbreak south of the border, but reminder of ongoing zoonotic risk of HPAI. www.canada.ca/en/public-he...

canada.ca

Statement from the Public Health Agency of Canada: Update on Avian Influenza and Risk to Canadians

The Public Health Agency of Canada (PHAC) today confirmed a human case of avian influenza (also known as bird flu) caused by influenza A(H5N1) virus in Canada.

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Marion Koopmans @marionkoopmans.bsky.social · 12/11/2024

Update on the H5n1 case in a teenager. Unfortunately very severe. Source remains unknown. Wastewater testing ongoing www.cidrap.umn.edu/avian-influe.... Not clear which lineage yet

cidrap.umn.edu

Canadian teen with suspected avian flu in critical condition

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Marion Koopmans @marionkoopmans.bsky.social · 10/11/2024

news.gov.bc.ca/releases/202... Still on X, but hear that many people mention bsky becoming more sciency. So will try to post every now and then. This one is something to keep an eye on. I am sure we will hear more from the Canadian public health office in the coming days

news.gov.bc.ca

First presumptive positive case of H5 avian influenza detected in B.C.

An individual in British Columbia has tested presumptive positive for avian influenza (also known as bird flu) caused by the H5 influenza virus, the first detection of avian influenza due to the H5 vi...

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Susan Hopkins @smhopkins.bsky.social · 30/10/2024

The UK has detected its first imported case of mpox clade Ib. Detected through alert patient, alert clinicians, diagnostic testing. Whole system response with @ukhsa and @nhse www.gov.uk/government/n...

gov.uk

UKHSA detects first case of Clade Ib mpox

The UK Health Security Agency (UKHSA) has detected a single confirmed human case of Clade Ib mpox.

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