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Joan Chang

@tranejoan.bsky.social
319 followers 148 following 38 posts

Chasing the👩🏻‍🔬dream: HKG-EDI-LDN-CPH-RDU-MAN| Matrix/⏰ biology | Disease microenvironment | MRC CDA Fellow @mcrcellmatrix.bsky.social @mcf-uom.bsky.social, University of Manchester | Mass Spec aficionado

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Joan Chang @tranejoan.bsky.social · 25/09/2026
The Chang lab has a few things to celebrate...including #MidAutumnFestival! 🌕🥮🏮
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Joan Chang @tranejoan.bsky.social · 03/07/2026
The jury has a very tough job to select the Dick Heinegård awardee! Vastly different topics, equally impressive. The future is very bright #ECMatrix #MBE2026
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Joan Chang @tranejoan.bsky.social · 03/07/2026
The future of #ECMatrix is very bright!! #MBE2026
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Joan Chang @tranejoan.bsky.social · 01/07/2026
The newly minted #RupertTimpl awardee, James Conway, on integrin phosphorylation and presenting really cool native ECM spot array to look at age-related changes in cancer migration. Very well deserved! #MBE2026
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Jan Gebauer @gebauer.bsky.social · 30/06/2026
Workshop #1 at #MBE2026 featured @tranejoan.bsky.social and @collagenyoshi.bsky.social back-to-back: first a wonderful talk on collagen trafficking, then a deep dive into lysine hydroxylation in collagens — asking the important question of how lysyl hydroxylases recognise their specific targets.
Joan Chang giving a talk at MBE 2026 in Oulu. Yoshihiro Ishikawa giving a talk at MBE 2026 in Oulu.
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Joan Chang @tranejoan.bsky.social · 29/06/2026
What an inspirational talk by Fiona Watt - beautiful data since 1990s, and the fact that something first seen in 1999 is followed up right now!! #MBE2026
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Joan Chang @tranejoan.bsky.social · 29/06/2026
What a wonderful first #ECR session hosted by @themeshwork.bsky.social! Join in the vibrant community and the future of #ECMatrix is super bright! #MBE2026
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Joan Chang @tranejoan.bsky.social · 29/06/2026
We are ready to start #MBE2026!! SHOUT-OUT to @valerioizzi.bsky.social for leading this conference, super excited about the next few days #ECMatrix #ScienceNoBoundaries
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Richard Barrett-Jolley @richardbj.bsky.social · 17/06/2026
Guest speaker Joan Chang… taking a break from rainy Manchester to visit Sunny Liverpool… Circadian rhythms in collagen and tissue repair.. @tranejoan.bsky.social
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Naba Lab UIC @nabalabuic.bsky.social · 25/02/2026
Registration for #MBE2026 is now open! Join us in Oulu 🇫🇮 for the flagship European meeting dedicated to fundamental #ECM research. ECRs and trainees, this is a unique chance to connect with leaders in the field, present your work, gain visibility, and build your network! More at www.mbe2026.org
Flyer of the Matrix Biology Europe conference listing invited speakers
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ASMB @amsocmatbio.bsky.social · 23/02/2026
👋Meet your presidents is back! We'll kickstart the week w/past presidents (Mon) followed by another PI (Thurs). Meet Jeff Miner 🥼2022 ASMB President, Prof at Washington University School of Medicine, studying #BasementMembranes and #kidney. Check out the full interview 👉🏻 youtu.be/LX6afqQ-G0k
youtu.be
Meet Our Presidents: Jeff Miner
YouTube video by ASMB - American Society for Matrix Biology
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Valerio Val Izzi @valerioizzi.bsky.social · 20/02/2026
Spatial transcriptomics (ST) should be conductive to anyone who has done microscopy in their lives, but it's not! Resolution vs coverage tradeoffs, static workflows, heavy data analysis still plague it... IT'S TIME TO CHANGE THIS!! INTRODUCING NaVis www.biorxiv.org/content/10.6...
biorxiv.org
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Joan Chang @tranejoan.bsky.social · 17/02/2026
Happy #ChineseNewYear2026 from the Chang lab! #LabDinner #年年有鱼 #福气临门
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ASMB @amsocmatbio.bsky.social · 17/02/2026
Next up: Douglas Gould, PhD 👁️ 2026 President-elect of the ASMB and Professor at the University of California, San Francisco. His work links ECM biology to vision and disease. ✨ Watch: youtu.be/9S3qPxUEBgg #MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
youtu.be
Meet Our Presidents: Doug Gould
YouTube video by ASMB - American Society for Matrix Biology
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ASMB @amsocmatbio.bsky.social · 17/02/2026
Meet Thomas H. Barker, PhD 🔬 2026 President of the American Society for Matrix Biology and Professor at the University of Virginia. His lab studies ECM signaling, repair, fibrosis, and regeneration. 👀 Watch his full #ASMB2025 interview youtu.be/Dw_BVGWkI94 #MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
youtu.be
Meet Our Presidents: Tom Barker
YouTube video by ASMB - American Society for Matrix Biology
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ASMB @amsocmatbio.bsky.social · 17/02/2026
Say hello to Ambra Pozzi, PhD 🧬 Past President of the #ASMB, whose leadership helped shape the community we celebrate in our #ASMB2025 interview series. 🎥 Watch the full interview: youtu.be/7Ys0rsieCiE #MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
youtu.be
Meet Our Presidents: Ambra Pozzi
YouTube video by ASMB - American Society for Matrix Biology
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Madhvi Menon @madhvimenon.bsky.social · 17/02/2026
We're excited to share our latest publication on immune dysfunction in refractory MG! Huge shoutout to the brilliant clinical scientist @katycdodd.bsky.social - from patient recruitment across the country to experiments and data analysis, you did it all! Can't wait to see what you do next 🌟
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Joan Chang @tranejoan.bsky.social · 17/02/2026
Happy Chinese New Year!
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DGMB @matrixbiologie.bsky.social · 05/02/2026
📣Wondering what to expect from our next annual meeting? Planning your journey? Our preliminary program is now live! Don't forget to submit your abstracts!!! #matrixbiology @dsmb-dk.bsky.social @mbsanz.bsky.social @amsocmatbio.bsky.social @themeshwork.bsky.social www.matrixbiologie.de/annual-meeti...
matrixbiologie.de
Annual Meeting 2026 - DGMB
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Joan Chang @tranejoan.bsky.social · 06/11/2025
Had a wonderful time as usual! Really fantastic to see so many new #ECMatrix young scientists from diverse institutions, with exciting projects 💪🏻 and superb hosting (and organisation) from @ccstorytime.bsky.social of course (should've taken more food photos)!
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Joan Chang @tranejoan.bsky.social · 20/10/2025
📢 2 very exciting PhD opportunities, please share! We use a range of technologies+systems to study #collagen, #ECMatrix, and #fibrosis 👇 1) MRC CASE DTP - #3D #biomaterials, #immune cells alter, #drugscreens lnkd.in/e6eMqs8M 2) Bicentenary - #macrophages, #circadian, #omics. lnkd.in/ekZfJfsd
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Joan Chang @tranejoan.bsky.social · 20/10/2025
My office for the next week or so, good to be back at HKU.
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Sandrine Le Goff @sgosfflv.bsky.social · 04/10/2025
Looking for a PhD ? Don’t miss ⬇️ 12 PhDs available in the REMOD-HEALING European doctoral network, funded by Horizon Europe's MCSA-DN program, in Europe and Costa Rica ! www.euraxess.fr/jobs/375945 @themeshwork.bsky.social @matrixbiologie.bsky.social #ECM #collagen #WoundHealing #proteases
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Andrew Porter @retropz.bsky.social · 01/10/2025
Thoughtful (and hopeful) reflections on the state-of-play for #ResearchCulture assessment as part of #REF2029 and the #REFPCE indicators project: wonkhe.com/blogs/is-res... "We don’t need all the answers for 2029, but we shouldn’t discard the tangible progress made"
wonkhe.com
Is research culture really too hard to assess?
Yolana Pringle and Ben Tatler make the case that the REF pause should be the moment to build on the most substantial sector-wide collaboration ever undertaken on research environments
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Judi Allen @profjudiallen.bsky.social · 30/09/2025
Become part of our new MRC Centre, working across Manchester and Oxford to solve a major challenge of our time - how does the immune system become dysregulated by environmental exposures to cause chronic disease. www.manchester.ac.uk/exposome-jobs @exposomeimmunology.bsky.social
bmh.manchester.ac.uk
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PLOS Biology @plosbiology.org · 29/09/2025
The liver #transcriptome is highly sensitive to metabolic cues. By characterizing nuclear protein #OGlcNAcylation in mouse #liver during the day, @joanna-chiu.bsky.social &co show how shifts in a nutrient-sensitive #PTM may shape transcriptional regulation @plosbiology.org 🧪 plos.io/3KuS7m1
Model describing how daily rhythmic O-GlcNAc proteome integrates environmental and metabolic signals to regulate transcriptomic and physiological rhythms. Environmental cues signaling through the molecular clock and metabolic cues from feeding–fasting cycles regulate daily rhythms in the O-GlcNAc proteome. Rhythmic O-GlcNAcylation can directly shape daily rhythmicity in transcriptome and physiology. In addition, rhythmic O-GlcNAcylation can also interact with rhythmic phosphorylation. Different forms of crosstalk between O-GlcNAc proteome and phosphoproteome are shown in the middle box. The red solid arrows indicate the regulations described in this study, while the dashed arrow indicates regulations discovered by previous studies. Figure created using BioRender.com.
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Joan Chang @tranejoan.bsky.social · 30/09/2025
New review! Towards a unified framework for the function of ER exit sites www.nature.com/articles/s41...
nature.com
Towards a unified framework for the function of endoplasmic reticulum exit sites - Nature Reviews Molecular Cell Biology
Endoplasmic reticulum exit sites (ERES) are specialized ER subdomains that regulate the export of secreted cargo. This Roadmap explores how ERES integrate biochemical and mechanical signals to coordinate trafficking and proposes a multidisciplinary strategy to investigate their function, including in disease.
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ASMB @amsocmatbio.bsky.social · 18/09/2025
🎉 Happy Postdoc Appreciation Week 2025! 🎉 At ASMB, we’re celebrating the innovators of tomorrow — our incredible PhD students & postdocs who are driving discovery every day. 👉ASMB members, want to be featured?: We are still accepting Submissions! #ASMBPAW2025 #ASMBTrainees #ECMatrix
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Joan Chang @tranejoan.bsky.social · 29/07/2025
It's been a great conference hearing all the other research findings and lots of new ideas - food for thought for everyone! Wish I didn't have to leave earlier...
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Stockmann Lab University of Zurich @stockmannlab.bsky.social · 28/07/2025
Great to meet with @tranejoan.bsky.social
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Joan Chang @tranejoan.bsky.social · 27/07/2025
Awesome talk (as expected) by @stockmannlab.bsky.social on targeting fibrogenesis, at the #SclerodermaWorkshop - first reunion since #KeystoneFobrosis2022!
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Joan Chang @tranejoan.bsky.social · 11/07/2025
Yesterday I attended the #graduation of my #firstPhD student Katie Lowles. What a moment! No longer her PI but still feeling very proud @mcf-uom.bsky.social @mcrcellmatrix.bsky.social (Oh and I also attended my first ever #GRCCollagen...it was awesome even though I had to leave early!)
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The Meshwork @themeshwork.bsky.social · 18/06/2025
Our final online seminar of the season is just around the corner!!! Save the date: June 25, 3pm CET. Register for FREE now and join us next week to discuss all things Hyaluronan in Medicine with Dr Laura Alaniz!!! Follow the QR code or click here: forms.gle/iSjnrLBVZmkD... @amsocmatbio.bsky.social
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ASMB @amsocmatbio.bsky.social · 02/06/2025
📢 IMPORTANT DATE ALLERT! Excited for the ASMB 2025 Biennial Meeting in Baltimore, Nov 16–19! Early Bird Registrations and Abstract submission deadline approaching—Don't forget to sign up first, then submit your abstract. See you there! #ASMB2025 #ASMBaltimore2025 #ECMatrix
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Joan Chang @tranejoan.bsky.social · 27/05/2025
Looking forwards to talking about #collagen and #circadian (or otherwise!) tomorrow!
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Joan Chang @tranejoan.bsky.social · 12/05/2025
Not sure I'm the expert, but definitely we're all about the #ECMatrix with a dabble of #CircadianRhythms 😆
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Rasmus Jensen @rasmusjensen.bsky.social · 28/04/2025
Are you into cryo-ET, in-cell discovery, protein translocation and folding or just cool integration of structural biology, proteomics and bioinformatics? Then see our new work: www.biorxiv.org/content/10.1... Thank you to all coauthors for your amazing work!
biorxiv.org
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Joan Chang @tranejoan.bsky.social · 14/04/2025
It's starting! #BSMB2025 with a very international delegate pool #ECMatrix #ScienceNoBoundaries
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Joan Chang @tranejoan.bsky.social · 10/04/2025
So professional (until it got to my part, so flustered!) - it's been a wonderful meeting and it's exciting to see a YouTube channel!! #ECMatrix #ScienceNoBoundaries
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Joan Chang @tranejoan.bsky.social · 06/04/2025
Incredible. "David Liu – a professor at the Broad Institute of MIT and Harvard, a biomedical research facility in Massachusetts – has marked Thanksgiving by handing over his entire annual salary to the staff and students in his laboratory." www.theguardian.com/science/2025...
theguardian.com
Biologist whose innovation saved the life of British teenager wins $3m Breakthrough prize
Prof David Liu is among the winners of 2025’s ‘Oscars of science’, with honours also going to researchers for landmark work on multiple sclerosis, particle physics and ‘skinny jabs’
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ASMB @amsocmatbio.bsky.social · 17/03/2025
Join us 3/26! #MeetTheSpeaker #2: Dr. Simona Plesselova (@simastatina), postdoc in @delapuente_lab who will share here latest work on Targeting #ECM to Reprogram Hypoxic Immunologically Cold #OvarianTumor Info & registration: asmb.net/e-symposia #ECMatrixIsEverywhere #WomensHealth
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ASMB @amsocmatbio.bsky.social · 14/03/2025
Don't forget to join our next #eSymposium organized by @delapuente_lab & @GonzalezPLab on the Intersection of Women’s Health & the ECM. #MeetTheSpeaker: Brandon J Vogt (www.linkedin.com/in/brandon-vogt-1028/) Info & registration: www.asmb.net/e-symposia #ECMatrixIsEverywhere #WomensHealth
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Joan Chang @tranejoan.bsky.social · 11/03/2025
We're ready for #BritishScienceWeek @ManchesterMuseum! All about #secretion, #ECMatrix assembly, from cells to #zebrafish! @mcrcellmatrix.bsky.social @mcf-uom.bsky.social
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Joan Chang @tranejoan.bsky.social · 07/03/2025
Standing in spirit with my US colleagues 💪🏻 #ScienceNoBoundaries #ECMatrix
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Joan Chang @tranejoan.bsky.social · 05/03/2025
Our lab's #1st manuscript from our #1st #PhD Katie is on #bioRxiv! Check it out 👇🏻 #macrophage regulation of fibroblast #collagen #circadian rhythm. #ImmunoECMatrix w/ @profandrewmac.bsky.social @tracyh9494.bsky.social @mcrcellmatrix.bsky.social @mcf-uom.bsky.social www.biorxiv.org/content/10.1...
biorxiv.org
Macrophages promote collagen deposition through circadian regulation of fibroblasts
Collagen deposition in fibroblasts, the primary collagen-producing cells, is regulated by both macrophages and the circadian rhythm, although how these regulatory processes interact with one another i...
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ASMB @amsocmatbio.bsky.social · 03/03/2025
We #ASMB stand up for #science on March 7 2025 - Because science is for and impacts everyone! Find your local rally site and other ways to get involve here: standupforscience2025.org #ECMatrixIsEverywhere #StandUpForScience2025 #ScienceNotSilence #ScienceForAll
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ASMB @amsocmatbio.bsky.social · 26/02/2025
We are #celebrating #BlackHistoryMonth by highlighting some of our members! New entries are still welcomed, so keep them coming!
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Joan Chang @tranejoan.bsky.social · 21/02/2025
Today we're seeing @KatieLowles off to her new adventure in #SciComm #ScientificWriting (with me being sad but proud about it) #proudPI
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Joan Chang @tranejoan.bsky.social · 18/02/2025
#ECMatrix guides #CellFate and patterning www.nature.com/articles/s41...
nature.com
Coupling of cell shape, matrix and tissue dynamics ensures embryonic patterning robustness - Nature Cell Biology
Moghe et al. show that mouse embryonic primitive endoderm cells migrate towards the inner cell mass-cavity interface, depositing an extracellular matrix gradient that may guide migration. Primitive en...
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Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 14/02/2025
It’s been buried in all the news today, but every scientist in the US should pay attention to this: Mike Lauer went out on a limb for us all, sending out a memo saying institutes should start awarding grants. And it looks like Trump/Musk fired him for that. 🧪
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