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Malcolm Campbell

@malcolmgcampbell.bsky.social
374 followers 260 following 37 posts

Assistant professor of neuroscience, Columbia University | Bridging theory and biology of animal learning and decision making

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Malcolm Campbell @malcolmgcampbell.bsky.social · 27/09/2026
One of my all time faves
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Daniel Cardozo Pinto @dcardozopinto.bsky.social · 22/06/2026
Delighted to receive the Henry Grass Rising Star in Neuroscience Award! 🎉 A huge thank you to the Grass Foundation for their recognition and support
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Malcolm Campbell @malcolmgcampbell.bsky.social · 23/06/2026
Not this summer, but hopefully in future summers!
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Malcolm Campbell @malcolmgcampbell.bsky.social · 23/06/2026
Thanks, Ishmail!
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Malcolm Campbell @malcolmgcampbell.bsky.social · 23/06/2026
Please reach out if you’re interested in tackling hard neuroscience problems, in a great community, in a cool city! 🧠🌆 @zuckermanbrain.bsky.social
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Malcolm Campbell @malcolmgcampbell.bsky.social · 23/06/2026
I hope to pay it forward by creating a supportive and fun training environment that produces rigorous, badass scientists. 👩‍🔬
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Malcolm Campbell @malcolmgcampbell.bsky.social · 23/06/2026
I'm SO grateful to all the mentors, collaborators, colleagues, and friends who have helped me in uncountable ways on this path so far, especially my primary mentors @naoshigeuchida.bsky.social and @lgiocomo.bsky.social!!
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Malcolm Campbell @malcolmgcampbell.bsky.social · 23/06/2026
I’m excited to closely collaborate with theorists and leverage the latest molecular, optical, and electrophysiological tools in mice. 🐀🔬⚡🧪
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Malcolm Campbell @malcolmgcampbell.bsky.social · 23/06/2026
This includes how key parameters governing learning and decision making, like the time discount rate, arise from synaptic and circuit mechanisms: www.biorxiv.org/content/10.1...
biorxiv.org
A hardwired neural circuit for temporal difference learning
The neurotransmitter dopamine plays a major role in learning by acting as a teaching signal to update the brain’s predictions about rewards. A leading theory proposes that this process is analogous to...
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Malcolm Campbell @malcolmgcampbell.bsky.social · 23/06/2026
The lab will focus on how the mammalian brain implements and tunes learning algorithms across timescales relevant to natural behavior. 🕑🤔
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Malcolm Campbell @malcolmgcampbell.bsky.social · 23/06/2026
Excited to share that I’ll be joining Columbia's Zuckerman Institute as an assistant professor of neuroscience, starting in September! 🧵
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Jeremiah Cohen @jeremiahycohen.bsky.social · 18/06/2026
Excited to move to the Department of Neuroscience at the University of Minnesota in the fall. We will continue our work on neuromodulators and behavior. Positions available in the lab. Please get in touch if interested, and share broadly! hr.myu.umn.edu/jobs/ext/374... hr.myu.umn.edu/jobs/ext/374...
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Malcolm Campbell @malcolmgcampbell.bsky.social · 05/06/2026
Nice to see our study highlighted in the Transmitter!
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Malcolm Campbell @malcolmgcampbell.bsky.social · 10/04/2026
Very cool - congratulations!
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Lisa Giocomo @lgiocomo.bsky.social · 02/04/2026
New paper! Congrats to @markplitt.bsky.social, Konstantin and team! The brain’s spatial map isn’t static but for hippocampus CA1 maps to change with experience, they need postsynaptic membrane fusion. A new link between synaptic machinery and flexible coding! www.sciencedirect.com/science/arti...
sciencedirect.com
Hippocampal place code plasticity in CA1 requires postsynaptic membrane fusion
Rapid delivery of glutamate receptors to the postsynaptic membrane via vesicle fusion is a central component of synaptic plasticity. However, it is un…
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Mark Plitt @markplitt.bsky.social · 03/04/2026
My final paper from grad school is out! Thank you to @marisosa.bsky.social @ellasay.bsky.social and my co-first author Konstantin Kaganovsky! We show that reward and novelty coding in the hippocampus requires a specific membrane fusion protein implicated in activity-dependent AMPAR mobilization!
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Tim Behrens @behrenstimb.bsky.social · 23/03/2026
What are the systems in neuroscience that we really have something that we can call “explanation” at all relevant levels, other than reflexive feed-forward like circuits. Here are a few that I would argue are getting there. Obviously not complete explanations but genuinely satisfying.
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Malcolm Campbell @malcolmgcampbell.bsky.social · 14/03/2026
Congrats, Matt!!! Super cool work.
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Christine Grienberger @cgrienberger.bsky.social · 02/03/2026
We’re looking for a new Research Tech! Our research tech is heading to graduate school (very exciting!), which means we’re recruiting someone new to join our team. The position involves hands-on neuroscience research in a collaborative environment. brandeis.wd5.myworkdayjobs.com/Jobs/job/Bra...
brandeis.wd5.myworkdayjobs.com
Research Technician
Research Technician position available in the Grienberger lab at Brandeis University. We are a new neuroscience group studying the cellular basis of learning and memory in the mammalian brain. This is...
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Jaeeon Lee @jel0624.bsky.social · 21/02/2026
🚨🚨New Preprint Alert!🚨🚨 www.biorxiv.org/content/10.6... Animal learning is painfully slow (at least initially). Yet, well trained animals can learn very fast, sometimes displaying few-shot inference. How does this transition occur?
biorxiv.org
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Malcolm Campbell @malcolmgcampbell.bsky.social · 05/01/2026
Isn’t calcium likely to be more compartmentalized than voltage?
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Mark Plitt @markplitt.bsky.social · 15/12/2025
I am incredibly excited and proud to share my first preprint from my postdoc! Thank you to all of the co-authors for all your hard work! Check out the paper for big insights into plasticity mechanisms in navigation circuits! And surprising motifs for inhibitory synaptic plasticity!
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Catherine Dulac @dulaclab.bsky.social · 13/12/2025
New paper alert!!...🤩 Led by @blogeman.bsky.social, we identify how cell type-specific hormonal responses in the hypothalamus tunes parenting behavior in males and females 🐭🧠🍼. Highlights in thread 👇 1/6 www.biorxiv.org/content/10.6...
biorxiv.org
Cell Type-Specific Hormonal Signaling Configures Hypothalamic Circuits for Parenting
Parenting behavior emerges from hormonally sensitive circuits, but how distinct circuit components are affected by, and contribute to, sex and state dependent changes in infant caregiving remains uncl...
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Catherine Dulac @dulaclab.bsky.social · 09/12/2025
I am thrilled to share our latest work led by @zurisullivan.bsky.social in collaboration with @moffittlab.bsky.social ! We find that the brain encodes distinct, pathogen-specific sickness states across behavior, physiology, neural activity, and gene expression 1/6 www.biorxiv.org/content/10.6...
biorxiv.org
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Malcolm Campbell @malcolmgcampbell.bsky.social · 10/12/2025
This is insane
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Catherine Dulac @dulaclab.bsky.social · 25/11/2025
Congratulations to my wonderful colleague Nao Uchida @naoshigeuchida.bsky.social now Jeff C. Tarr Professor! 👏🤩🧠🎉
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Malcolm Campbell @malcolmgcampbell.bsky.social · 21/11/2025
Gorgeous. The trumpet player is Nils Petter Molvær, a well known jazz musician. Love the combination.
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MwahahahahahadScientist @mads100tist.bsky.social · 16/11/2025
"Postdoc in the job market"
A headline:

Scientists have discovered a 'third state' between life and death
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Kelsey Tyssowski @kelseytea.bsky.social · 13/11/2025
Heading to San Diego for #sfn25 today! I’ll be presenting a poster on this work Monday afternoon! looking forward to meeting neuroscientists! please stop by my poster or reach out if you’re going and want to talk motor neuro/behavior, evolution, neuroethology…or whatever else! 🧠🥳 #neuroskyence
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Malcolm Campbell @malcolmgcampbell.bsky.social · 13/11/2025
For anyone attending the pre-SFN Molecular and Cellular Cognition Society meeting, I'll be giving a short talk there on Friday (Nov 14) at 4:20 pm event.fourwaves.com/MCCS25/pages
event.fourwaves.com
Molecular and Cellular Cognition Society 2025 Annual Meeting
Fourwaves - Molecular and Cellular Cognition Society 2025 Annual Meeting
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Malcolm Campbell @malcolmgcampbell.bsky.social · 13/11/2025
I'll be presenting a poster on this at SFN on Monday morning, poster QQ5. Come say hi! Looking forward to hearing about all the great science everyone's been doing!
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Ilana Witten @ilanawitten.bsky.social · 07/11/2025
How do VTA DA neurons sculpt downstream representations to reinforce actions? VERY excited about our new preprint (by Alex Pan Vazquez & @czimmerman.bsky.social )
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Alex @alexattinger.bsky.social · 24/10/2025
How does the brain balance learning new things without overwriting what it already knows? Our new paper tackles this long-standing stability–plasticity dilemma during active navigation. With Tony Drinnenberg from the Deisseroth Lab (@deisseroth.bsky.social) doi.org/10.1101/2025...
doi.org
Environmental Novelty Modulates Rapid Cortical Plasticity During Navigation
In novel environments, animals quickly learn to navigate, and position-correlated spatial representations rapidly emerge in both the retrosplenial cortex (RSC) and primary visual cortex (V1). However,...
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Kelsey Tyssowski @kelseytea.bsky.social · 22/10/2025
🧠🌟🐭 Excited to share some of my postdoc work on the evolution of dexterity! We compared deer mice evolved in forest vs prairie habitats. We found that forest mice have: (1) more corticospinal neurons (CSNs) (2) better hand dexterity (3) more dexterous climbing, which is linked to CSN number🧵
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Malcolm Campbell @malcolmgcampbell.bsky.social · 15/10/2025
Thanks Ben!
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Malcolm Campbell @malcolmgcampbell.bsky.social · 11/10/2025
Ezra Klein show?
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Ann Kennedy @antihebbiann.bsky.social · 09/10/2025
Finally out: our recent work with Nick Betley is a view into how the brain reshapes its behavior in the face of competing survival needs- and also a potential angle on treatment targets for enduring pain. A brief rundown... www.nature.com/articles/s41...
nature.com
A parabrachial hub for need-state control of enduring pain - Nature
Activity in a set of parabranchial neurons in the mouse brain is increased during chronic pain, predicts coping behaviour, and can be modulated by circuits activated by survival threats.
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Nick Jourjine @nickjourjine.bsky.social · 06/10/2025
Had a blast writing about this new @currentbiology.bsky.social study from @leo-perrier.bsky.social, Lény Lego et al. on African striped mice The paper: doi.org/10.1016/j.cu... Dispatch with some context about why it's so cool: authors.elsevier.com/a/1luVG3QW8S... #bioacoustics #neuroskyence
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Fanny Cazettes @fannycazettes.bsky.social · 30/09/2025
Did you know that facial expressions reveal more than meets the eye? 🤯 Our new study shows that even a mouse's face 🐭 can reflect hidden neural computations🧠. Turns out, facial expressions are more than just emotions! We're so excited to see this paper out @natneuro.nature.com 🎉 🔗: rdcu.be/eIQzO
rdcu.be
Facial expressions in mice reveal latent cognitive variables and their neural correlates
Nature Neuroscience - The face reveals more than just emotion. Cazettes, Reato and colleagues show that subtle facial movements reveal hidden cognitive states, reflecting the brain’s ongoing...
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Malcolm Campbell @malcolmgcampbell.bsky.social · 29/09/2025
Thanks Kameron!
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Malcolm Campbell @malcolmgcampbell.bsky.social · 29/09/2025
Also thank you, I’m really glad you enjoyed it!
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Malcolm Campbell @malcolmgcampbell.bsky.social · 29/09/2025
It didn’t make it into the preprint but dopamine neurons respond to D2 stim as a sign-flipped TD error, which fits nicely in that framework
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Malcolm Campbell @malcolmgcampbell.bsky.social · 29/09/2025
Great question… my current thinking based on plasticity rules is that they learn pessimistically biased sign-flipped value from dopamine dips, as in @sromeropinto.bsky.social’s and Adam Lowet’s papers
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Malcolm Campbell @malcolmgcampbell.bsky.social · 21/09/2025
Thanks Alex!
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Malcolm Campbell @malcolmgcampbell.bsky.social · 20/09/2025
Thank you!
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Malcolm Campbell @malcolmgcampbell.bsky.social · 20/09/2025
Thank you Laura!
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Malcolm Campbell @malcolmgcampbell.bsky.social · 19/09/2025
Thanks Adrien! Yes, that’s exactly right!
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Malcolm Campbell @malcolmgcampbell.bsky.social · 19/09/2025
Thanks Eddy!
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Malcolm Campbell @malcolmgcampbell.bsky.social · 19/09/2025
Thank you Sam! It was super fun to present in your lab!
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Malcolm Campbell @malcolmgcampbell.bsky.social · 19/09/2025
Thanks so much to all co-authors, especially my mentor Naoshige Uchida @naoshigeuchida.bsky.social! It has been a joy to work on this (ongoing) project!
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