Reposted by @madlybarmy.bsky.social
🐒 In monkeys, how COVID gets in beats dose
Pooling 107 experiments on 721 monkeys and other primates shows the entry route shapes infection more than dose, age, sex, or species. Route also decides which tissues get infected.
🔗 doi.org/10.1126/sciadv.aei4853
#COVID19 #Virology #Health 🧪
doi.org
Exposure route, not dose, is the primary driver of infection patterns for a respiratory virus
Infectious disease severity, shedding, and within-host kinetics can vary substantially with exposure dose, inoculation route, and host factors. However, the relative contributions of these variables t...