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Brain-wide transcriptomic profiling in mice reveals that reproductive experience remodels the maternal brain by altering dopamine dynamics in the dorsal hippocampal formation, causing dopamine-depende...

Molecular drivers of sex-specific brain plasticity are unknown. Here, authors show estrogen-driven Egr1 controls chromatin accessibility sex-dependently, driving gene expression, structural plasticity...

We know little about the mechanisms underlying well-known perimenopause symptoms in the brain. More research—in animals and humans—is essential.

A biology professor is examining the links between menopause and depression, anxiety, and other mental illnesses, building on a pioneering study she and her team just published.

ALT: a woman is sitting on a couch with her legs crossed

The topographical organization of cells in the hippocampus reflects its ability to regulate mood and cognition. Here the authors generate a spatially resolved gene expression map in the human hippocam...

Ovarian hormones, particularly estradiol, play an important role in the regulation of metabolic function including in food intake, thermogenesis, acti…

To conduct scientifically accurate and socially responsible research, think of “sex” as a complex, multifactorial and context-dependent variable.

Maternal aggression is a core feature of rodent maternal behaviour to defend their offspring from potential threats and is modulated by corticotropin-releasing factor (CRF) and oxytocin (OXT) systems ...