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Luc Estebanez

@lucestebanez.bsky.social
303 followers 369 following 45 posts

Brain-machine interfaces, Neuroprostheses. CNRS, Paris-Saclay Institute of Neuroscience @NeuroPSI.bsky.social neuropsi.cnrs.fr/annuaire/luc-esteb… Member of team @TouchMoveLab.bsky.social

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Reposted by Luc Estebanez
Gro-Tsen @gro-tsen.bsky.social · 27/08/2026
Leaving aside questions about how desirable or opportune it is for mathematicians to use AI in their research, I am troubled by how many colleagues have told me they pay a “pro” subscription to this-or-that AI model ❊with their own personal money❊.
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Tanuj Gulati @tanujgulati.bsky.social · 18/08/2026
🧠 #Job alert! Postdoctoral position in my lab at Cedars-Sinai: electrophysiology & cortico-cerebellar dynamics in stroke recovery. Full ad below. Please share! #Neuroscience #Postdoc #Neuromodulation #Neuroprosthetics #Cerebellum #BCI #Stroke
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Laetitia Mony @laetitiamony.bsky.social · 06/07/2026
Heading to #FENS2026! First step: 6h50 of train to Bracelona. Please go check the team posters tomorrow morning 👇. I will talk in the photopharmacology session Friday morning. Looking forward to meeting the Neuroscience community !
PS01-07AM-015. Lara Pizzamiglio. GluN1/GluN3 excitatory glycine receptors control ventral hippocampal plasticity and anxiety-related behaviors 

PS01-07AM-016. Sofia Blazquez. Functional expression of GluD1 receptors in the hippocampal CA2 field
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Luc Estebanez @lucestebanez.bsky.social · 06/07/2026
Check out in particular our posters on brain-machine interfacing and mouse upper-limb prostheses on Tuesday morning; my work with James Poulet on sensorimotor integration in forelimb M1 with membrane potential recordings on Wednesday afternoon, and more amazing somatosensory-motor work on Thursday!
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Reposted by Luc Estebanez
Sensori-motor Integration and Plasticity Lab @touchmovelab.bsky.social · 06/07/2026
FENS 2026: We will present our BMI, mouse neuroprosthesis and somatosensory processing work through this week, including chairing a session on circuit neuroscience in freely moving mice! Check out the schedule below 🔽🔽🔽
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Marc Slutzky @marcslutzky.bsky.social · 22/06/2026
Our paper is now in print in Nature @nature.com. If you're interested in local field potentials, especially #high-gamma activity, and/or #spikes, check it out! TL;DR: High gamma is not mainly filtered spikes, but mainly summed nearby PSPs. www.nature.com/articles/s41...
nature.com
Active dissociation of intracortical spiking and high gamma activity - Nature
A brain–machine interface is used in monkeys to investigate the biophysical underpinnings of cortical high gamma-band activity, a signal that is often studied in the context of many brain functions.
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Reposted by Luc Estebanez
Sam Schwarzkopf @sampendu.bsky.social · 27/05/2026
I know this was a labour of love (and blood, sweat, and tears) by my great colleague Susanne Stoll: the first ever tactile maps of the human finger tip! ☝️ #neuroskyence (not really #psychscisky or #visionscience but tagged it anyway 😉) doi.org/10.1162/IMAG...
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Reposted by Luc Estebanez
Arrêt sur images @arretsurimages.net · 11/06/2026
INFO ASI - Étienne Klein perd son doctorat 🚨 Le plagiat de sa thèse, révélé par Arrêt sur images en 2024, vient d'être confirmé à l'issue de 20 mois d’enquête : près de deux tiers des pages seraient concernées. Plus d'infos ⤵️ www.arretsurimages.net/articles/the...
arretsurimages.net
Thèse plagiée : Étienne Klein perd son doctorat - Par Loris Guémart | Arrêt sur images
Peu après les révélations de plagiat dans la thèse d'Étienne Klein par "Arrêt sur images" en 2024, l'Université Paris Cité avait ouvert une enquête. À la suite de 20 mois de procédure, elle a découver...
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Luc Estebanez @lucestebanez.bsky.social · 03/05/2026
Worrying development: a Nobel-grade Harvard nanochemist, convicted of treason, and fleeing to China to head a neurotechnology research effort involving massive volumes of monkey research and ASML-levels of chip microfabrication....
japantimes.co.jp
Convicted former Harvard scientist rebuilds brain computer lab in China
Scientists at China's People's Liberation Army have investigated brain interfaces as a way to engineer super soldiers by boosting mental agility and situational awareness.
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Reposted by Luc Estebanez
Nicolas Hénin @nicolashenin.net · 20/04/2026
Moisissures dans les collections, bibliothèque inondée, fissures dans les murs… Alors que le @mnhn.fr célèbre ses 400 ans, fort d’une importante fréquentation et d’une renommée scientifique internationale, son président, Gilles Bloch, alerte sur son état catastrophique.
lemonde.fr
L’appel à l’aide du Muséum national d’histoire naturelle, très délabré : « Les ossements minéralisés explosent littéralement »
Moisissures dans les collections, bibliothèque inondée, fissures dans les murs… Alors que l’établissement célèbre ses 400 ans, fort d’une importante fréquentation et d’une renommée scientifique intern...
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Reposted by Luc Estebanez
PLOS Biology @plosbiology.org · 20/04/2026
How does somatosensory input to the #MotorCortex contribute to limb movement? This study shows that loss of #somatosensory inputs disrupts voluntary forelimb movements & motor cortex neuronal dynamics, highlighting the role of somatosensory input in motor control @plosbiology.org 🧪 plos.io/3QcbXph
Summary of main findings. Left: Main contributions of the somatosensory inputs to the generation of motor activity in M1. Cortical state generation is independent from somatosensory inputs. Right: Schematic Vm modulations of an M1 neuron in an intact mouse (IT Vm) and in a nerve cut mouse (NC Vm) during a Quiet to Movement transition. The removal of forelimb inputs did not impact the occurrence of quiet/active periods in the membrane potential, but (1, vertical line) reduced pre-movement input; (2, gray box) reduced Vm correlations with ongoing forelimb movement; and (3, horizontal line) disrupted the reach reversal potential.
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Luc Estebanez @lucestebanez.bsky.social · 20/04/2026
▶️ In our new @plosbiology.org study with James Poulet, we show somatosensory contributions to M1 Vm in a forelimb reaching task. ▶️ Surgical removal of somatosensation impacted movement encoding, Vm regulation and its transition to active state, and more! ▶️ Learn more: doi.org/10.1371/jour...
Example forelimb reaching movements of a mouse, and simultaneous recording of the membrane potential in the primary motor cortex.
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Reposted by Luc Estebanez
Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · 26/02/2026
▶️ Heike Stein from Sorbonne Université will be the 4th keynote speaker at NeuroControl2026! ▶️ NeuroControl 2026, the conference on the physiology and engineering of limb and prosthesis closed-loop control! Register and submit your abstract: neurocontrol.sciencesconf.org
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Reposted by Luc Estebanez
Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · 19/02/2026
▶️ Henri Lorach from Université de Lausanne will be the 3rd keynote speaker at NeuroControl2026! ▶️ NeuroControl 2026, the conference on the physiology and engineering of limb and prosthesis closed-loop control! Register and submit your abstract: neurocontrol.sciencesconf.org
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Reposted by Luc Estebanez
Patrick Pla @patrickpla.bsky.social · 17/02/2026
First time seeing "for real" the new metro at #Saclay. The line will open (with a higher speed I hope) on October this year.
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Reposted by Luc Estebanez
Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · 16/02/2026
▶️ Daniel Häufle from Tübingen Universität will join us as a keynote speaker at NeuroControl2026! ▶️ NeuroControl 2026, the conference on the physiology and engineering of limb and prosthesis closed-loop control! Register and submit your abstract: neurocontrol.sciencesconf.org
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Luc Estebanez @lucestebanez.bsky.social · 12/02/2026
🎉 We will have a talk by Daniel Huber at the NeuroControl2026 conference! ➡️ Register: neurocontrol.sciencesconf.org
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Julie Carcaud @carcaudjulie.bsky.social · 10/02/2026
🧠 We are pleased to announce that applications for the M2 Systems Neuroscience at the University Paris-Saclay are officially open 🎉 www.universite-paris-saclay.fr/formation/ma... @univparissaclay.bsky.social @neuropsi.bsky.social
universite-paris-saclay.fr
M2 Systems Neuroscience: from cells to brain functions
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Nikolas Karalis @nikolaskaralis.bsky.social · 17/12/2025
We invite applications for postdoctoral researchers with strong expertise in in vivo electrophysiology and circuit neuroscience to join our team at the Paris Brain Institute (ICM).
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Laetitia Mony @laetitiamony.bsky.social · 28/01/2026
If you are a PhD student or post-doc who wants to learn everything about #electrophysiology or #imaging, consider registering to the Paris Spring school in optical imaging and electrophysiology, that will take place in the center of Paris 11-23 May 2026. Application deadline Feb 2nd parisneuro.ovh
parisneuro.ovh
Paris NeuroCourse | Optical Imaging and Electrophysiological Recording in Neuroscience
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Luc Estebanez @lucestebanez.bsky.social · 20/01/2026
We are organizing a conference on closed-loop limb control, looking at both robotic and physiological control. ▶️ Register, submit your abstract!
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Reposted by Luc Estebanez
Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · 20/01/2026
🦾/💪 Interested in the physiology of motor control? In robotics? In neuroprosthetics? ▶️ Join us in NeuroPSI for NeuroControl 2026, the conference on the physiology and engineering of limb and prosthesis closed-loop control! ▶️ Register and submit your abstract: neurocontrol.sciencesconf.org
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Pierre Le Merre @pierrelemerre.bsky.social · 20/01/2026
Main postdoc study out! We can redefine prefrontal cortex regions with single-unit activity! Grateful to @carlenlab.bsky.social and @weltgeischt.bsky.social who made this crazy project real. Thanks to all co-authors, collaborators, and reviewers. www.nature.com/articles/s41...
nature.com
A prefrontal cortex map based on single-neuron activity - Nature Neuroscience
The authors mapped spontaneous and choice activity across mouse prefrontal cortex. The activity maps aligned with intrinsic connectivity rather than anatomical subregions, suggesting that connectivity...
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Luc Estebanez @lucestebanez.bsky.social · 05/01/2026
🦾 🧠 Are you interested in building and experimenting with the second version of our mouse forelimb prosthesis? Apply to our Post-Doc position at Université paris-Saclay. Neuroscientists with interest for engineering, and engineers with interest for neurosciences all welcome! Apply now 🔽🔽🔽
emploi.cnrs.fr
Portail Emploi CNRS - Offre d'emploi - Chercheuse/chercheur post-doctorant en Neurotechnologie (H/F)
Assurez-vous que votre profil candidat soit correctement renseigné avant de postuler
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Idoia Quintana-Urzainqui @idoiaeu.bsky.social · 22/12/2025
Really happy to join NeuroPSI at Paris Saclay to lead a research group funded by an ERC Consolidator grant #ERCCoG . We'll study the origins of the vertebrate brain using shark embryos. 🦈 🧠 Reach out if you are interested in joining the team 🤍
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Luc Estebanez @lucestebanez.bsky.social · 10/12/2025
We have opened a call for a post-doctoral researcher ! Our team @touchmovelab.bsky.social researches strategies to provide direct cortical feedback during brain-machine interface control of an upper limb prosthesis in the mouse model.
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Nick Desnoyer @nickdesnoyer.bsky.social · 01/12/2025
The hidden danger of Biorender (& the death of scientific illustration) A short thread 🧵
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PLOS Biology @plosbiology.org · 16/10/2025
How to restore #motor function after #stroke? This study shows in mice that a combination of #RoboticRehabilitation & non-invasive gamma band #neuromodulation improves motor recovery by restoring movement-related oscillations & parvalbumin #interneuron dynamics @plosbiology.org 🧪 plos.io/4n7QJng
Enduring reduction of resting state functional connectivity (FC) of parvalbumin-positive interneurons (PV-INs) after stroke. Top left: Experimental timeline, with the cranial optical window implanted one week before the first imaging session. Imaging time point at −1 (PRE), 2, 5, 8, 14, 21, and 28 days after stroke. Top right: Left, representative image sequence of cortical PV-IN activity before stroke. The black dot indicates bregma. L: lateral; M: medial; R: rostral; C: caudal (Scale bar, 1 mm). Right, wide-field calcium imaging field-of-view aligned with the surface of the Allen Institute Mouse Brain atlas. The green area on the left hemisphere locates the damaged region. Yellow squares represent cortical areas defined in both left (L, contralesional) and right (R, ipsilesional) hemispheres. Red dot indicates bregma (Scale bar, 1 mm). Middle row: Pairwise Pearson’s correlation coefficients of cortical activity were visualized as averaged correlation matrices for each imaging time point after hemodynamic correction. Bottom row: Network diagrams of statistically significant FC alterations after 2, 5, 8, 14, 21, or 28 days from injury. Blue and red lines denote significant hyper-correlation and hypo-correlation compared to prestroke values, respectively.
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Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · 11/10/2025
🤯 👁️ Did you know the primary visual cortex tracks head movements even in complete darkness? Guy Bouvier and colleagues managed to decode multiple head movement variables in V1 without light in the room, and discovered two distinct brain sources delivering these signals! Read more in PNAS 🔽🔽
pnas.org
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Virginie van Wassenhove @virginievanw.bsky.social · 29/09/2025
Evenement à diffuser pour la fête de la science en @iledefrance.bsky.social @poncerlab.bsky.social @bathellierlab.bsky.social @clairewyart.bsky.social
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Luc Estebanez @lucestebanez.bsky.social · 04/09/2025
1/4 Today we introduce the first upper limb prosthesis for the mouse model, controlled by a brain-machine interface! We show that mice can control this prosthesis via a brain-machine interface to solve a rewarded task.
Left: the upper-limb prosthesis can collect water from a tank, and bring it close to the mouth. Right: skeleton of the prosthesis with 4 DOF. THis prosthesis relies on Bowden cables.
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Juan Gallego @juangallego.bsky.social · 07/08/2025
🚨 New preprint + thread 🧵 We've gone back to studying motoneuron control principles and their applications & here's paper #1: A proof-of-concept study showing that people with tetraplegic spinal cord injury can control up to 2DoF from a single intramuscular implant www.medrxiv.org/content/10.1...
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Micah G. Allen @micahgallen.com · 01/08/2025
Never thought I’d see the day when LinkedIn is the biggest driver of engagement in our papers, but we live in some strange times.
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Luc Estebanez @lucestebanez.bsky.social · 01/08/2025
1/6 We have a new/updated preprint out, led by Anton Dogadov, demonstrating operant conditioning of large cortical waves over mouse S1 thanks to a mesoscale GCamp6 brain-machine interface! www.biorxiv.org/content/10.1...
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Tanuj Gulati @tanujgulati.bsky.social · 21/07/2025
(1/8) Excited to share our new paper in @cp-cellreports.bsky.social , led by grad student @rohitrangwani.bsky.social ! 🧠🤖 We show that robust #BrainMachineInterface (#BMI) control is possible using #cerebellar activity- even in a #stroke-affected brain. #Neuroscience www.cell.com/cell-reports...
doi.org
Redirecting
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Science Magazine @science.org · 22/07/2025
Octopuses fall for the “rubber arm” illusion, just like us. Learn more: scim.ag/40xyT4y
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Michael Lin, MD PhD @michaelzlin.bsky.social · 17/07/2025
Two voltage imaging studies in two days using ASAP fluorescent indicators. First, visualizing electrical brain waves with ASAP3, in Cell. Free link below. Though recorded by EEG for 100 years, how brain waves arise from different neuron types has been unclear. authors.elsevier.com/sd/article/S...
authors.elsevier.com
ScienceDirect.com | Science, health and medical journals, full text articles and books.
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Julien Bouvier @jul-bouvier.bsky.social · 16/07/2025
Don't miss this upcoming informal gathering on the theme of SEARCHING FOR PRINCIPLES IN MOTOR CONTROL on Sept 23-24, 25 in Sorbonne University. It will enable you to present your work to the French motor community. Registration is free! motorconference.sciencesconf.org
motorconference.sciencesconf.org
Searching for Principles in Motor Control - Sciencesconf.org
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Brice Bathellier @bathellierlab.bsky.social · 13/07/2025
If you have missed it, wonderful workshop in Montpellier on most recent optical imaging techniques for neurosciences. One week left to register lnkd.in/etEmGyMm Visit workshop 284 Free registration, accomodation possible on site.
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Science Magazine @science.org · 07/07/2025
Scientists have developed OpenExo, an open source exoskeleton framework that could make wearable robotics more accessible and accelerate the development of new devices. Read more in #ScienceRobotics: scim.ag/4koYIKY
scim.ag
OpenExo: An open-source modular exoskeleton to augment human function
We present an open-source, open-hardware exoskeleton to aid in accelerating the growth of robotic exoskeleton research.
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CNRS Biologie @cnrsbiologie.bsky.social · 05/07/2025
Les souris ont-elles aussi une représentation cognitive de leur corps ? 🤝 @cnrs-paris-saclay.bsky.social @univparissaclay.bsky.social @lucestebanez.bsky.social @touchmovelab.bsky.social @neuropsi.bsky.social 👉 Lire l'article dans @plosbiology.org buff.ly/2JK2msI
buff.ly
Les souris ont aussi une représentation cognitive riche de leur corps
L’illusion de la « main en caoutchouc » montre que la manipulation astucieuse de perceptions visuelles et tactiles peut nous convaincre en quel
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Reposted by Luc Estebanez
Dominika Radziun @nikaradziun.bsky.social · 04/07/2025
How does the brain integrate artificial body extensions? Using a custom-built finger-extending exoskeleton, we show that wearable augmentations are quickly integrated into body representation, with proprioceptive space adapting to the device’s structure and function. www.biorxiv.org/content/10.1...
biorxiv.org
Dynamics of sensorimotor plasticity during exoskeletal finger augmentation
How does the brain integrate artificial body extensions into its somatosensory representation? While prior work has shown that tool use alters body representation, little is known about how artificial...
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Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · 02/07/2025
🎉 L'interdisciplinarité est à l'oeuvre dans notre institut. 🤝 Nos liens forts avec la communauté des ingénieurs du L2S @centralesupelec.bsky.social nous valent le label PRIME de @cnrs.fr !
miti.cnrs.fr
Le projet Neurocontrol : où les neurosciences rencontrent l’automatique – MITI
Retrouver l'interview des porteurs du projet Neurocontrol, fruit d’une collaboration entre neuroscientifiques et automaticiens
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Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · 28/06/2025
🔬🐁 We have a new position open! ➡️ Our "Chaire Professeur Junior" position focuses on multi-omics during brain development. This research-heavy position follows a tenure-track scheme, leading to a full professor position. 🗓️ Application deadline: 22/08/2025
universite-paris-saclay.fr
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Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · 25/06/2025
C'est notre grande tristesse d'annoncer le décès de Heather McLean, Maitresse de Conférence en neuroscience à @univparissaclay.bsky.social, chercheuse à @neuropsi.bsky.social.
Notre chère collègue et amie, Heather McLean, nous a quittés le 16 juin 2025, après s’être battue comme une lionne, avec beaucoup de courage et de détermination, contre le cancer. Canadienne de naissance, elle est arrivée en France en 1992 pour effectuer un postdoctorat dans le laboratoire de Jean Champagnat à Gif-sur-Yvette, où elle a étudié les réseaux de neurones impliqués dans les rythmes respiratoires. Après un second postdoctorat dans l’équipe de Yehezkel Ben-Ari en 1998, elle a été recrutée comme maître de conférences dans notre université. Elle y a enseigné la physiologie et les neurosciences avec passion, dynamisme et bonne humeur. Elle s’est également beaucoup investie dans la formation des professeurs des écoles en étant tout d’abord responsable d’un parcours dédié au sein de la Licence Sciences de la Vie, puis responsable de la Licence Sciences, Enseignement, Médiation. Heather McLean a contribué en première ligne à l'internationalisation des formations de l’Université Paris-Saclay, en tant que coordinatrice Erasmus+ pour le service des relations internationales, ainsi qu’en tant que directrice adjointe déléguée aux relations internationales de la graduate school Life Sciences and Health.
 
Parallèlement, Heather a mené des recherches sur les récepteurs métabotropiques au glutamate et à l’adénosine dans le cortex cérébelleux, dans l’équipe d’Hervé Daniel. En 2020, elle a rejoint l’équipe de Valérie Doyère où elle a développé une thématique centrée sur l’étude des effets de la manipulation des circuits neuronaux sur l’apparition d'états anxieux et de peurs à l’adolescence. Son HDR, intitulée From Synapses to Cognition, reflète bien son parcours : un véritable voyage au cœur du cerveau et au sein de NeuroPSI. 
 
Heather McLean était très appréciée de ses collègues et des étudiant·e·s envers qui elle se montrait toujours à l’écoute et bienveillante. Sa bonne humeur, son esprit collaboratif et sa curiosité nous manqueront à toutes et à tous, énormément.
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Pierre Le Merre @pierrelemerre.bsky.social · 26/06/2025
I am extremely grateful and beyond happy to share that I have been awarded an @inserm.fr #ATIP-Avenir fellowship to start my own lab to study neuronal circuits for auditory categorization! Thanks to everyone who made this possible.
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Zero-Noise Lab @zeronoiselab.bsky.social · 10/06/2025
Now out in @natcomms.nature.com‬: Mice and monkeys spontaneously shift through comparable cognitive states - and it's written all over their faces! (1/7) www.nature.com/articles/s41...
nature.com
Inferring internal states across mice and monkeys using facial features - Nature Communications
Here, the authors created a virtual reality task for monkeys and mice to explore if internal states like attention are similar across species. Their facial expressions during the task were similar, su...
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Brice Bathellier @bathellierlab.bsky.social · 15/06/2025
Two postdoc positions in the lab within the ERC Synergy project "Chronology" in collaboration with S. Ostojic, M. Jazayeri and V. van Wassenhove @virginievanw.bsky.social . Two focuses: sound sequences representations across the brain & novel all-optical technology. Contact: brice.bathellier@cnrs.fr
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Pierre Bataille @pierrebat.cpesr.fr · 12/06/2025
Du poids indéniable de l'école dans la production des inégalités genrées face aux mathématiques "Rapid emergence of a maths gender gap in first grade" par P. Martinot et al. Une étude sur 3 million d'enfants en France (!!!) qui va faire du bruit #LaRAC @nature.com www.nature.com/articles/s41...
Preventing gender disparities in mathematics is a worldwide preoccupation1,2. In infancy and early childhood, boys and girls exhibit similar core knowledge of number and space3,4,5,6,7,8. Gender disparities in maths are, therefore, thought to primarily reflect an internalization of the sociocultural stereotype that ‘girls are bad at maths’. However, where, when and how widely this stereotype becomes entrenched remains uncertain. Here, we report the results of a 4-year longitudinal assessment of language and mathematical performance of all French first and second graders (2,653,082 children). Boys and girls exhibited very similar maths scores upon school entry, but a gender gap in favour of boys became highly significant after 4 months of schooling and reached an effect size of about 0.20 after 1 year. These findings were repeated each year and varied only slightly across family, class or school type and socio-economic level. Although schooling correlated with age, exploiting the near-orthogonal variations indicated that the gender gap increased with schooling rather than with age. These findings point to the first year of school as the time and place where a maths gender gap emerges in favour of boys, thus helping focus the search for solutions and interventions.Ecart de genre en maths à T1 (début CP), T2 (janvier CP) et T3 (début CE1) en fonction de l'âge des enfants en mois lors de la passation du test, pour les quatre années de cohorte (d de Cohen). Étant donné que l'entrée à l'école est strictement déterminée par la date de naissance, les enfants du même âge peuvent différer dans leur durée de scolarisation (couleurs et lignes de régression). Quel que soit l'âge auquel ils ont passé le test, les enfants présentaient un écart minime ou nul entre les sexes en mathématiques à T1, mais l'effet s'est accentué après 4 mois (T2) et 12 mois (T3) de scolarisation.
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