iiinova — where your digital self keeps evolving

Luca Sclisizzo @luca-sclisizzo.bsky.social · 14/09/2026

I’m very happy to share my first “step in science” and I’m incredibly grateful to my coauthors and mentors who made it possible: @ecjohnson.bsky.social @davidbaranger.bsky.social @mclapps.bsky.social @alexanderhatoum.bsky.social Marco Del Giudice

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Luca Sclisizzo @luca-sclisizzo.bsky.social · 14/09/2026

These findings support a nuanced view of the psychosis spectrum, highlighting how different dimensions of genetic risk may contribute to its clinical and biological heterogeneity.

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Luca Sclisizzo @luca-sclisizzo.bsky.social · 14/09/2026

Using Genomic SEM we identified 4 components ranging from cognition-related psychosis to more affective components. We characterized the factors through enrichment analyses to better understand their biological similarities and differences, and looked at their genetic correlations with other traits.

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Luca Sclisizzo @luca-sclisizzo.bsky.social · 27/06/2026

#BGA26 was a blast! Happy to have had the opportunity to present my work in Amsterdam and share one of my favorite research topics. Thanks to @lydiarader.bsky.social, @tabeasch.bsky.social, and @evangiangrande.bsky.social for such a great discussion and for their amazing talks!

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Reposted by Luca Sclisizzo

Michel Nivard @michelnivard.bsky.social · 09/06/2026

Javier and Elliot (and the rest of us, all methodological credit them) did very smart methodological work to speed up GenomicSEM GWAS 800x... Basically they found and implemented a key closed form solution. Go do SEM over millions of SNPs, for tens of traits on a macbook, and it even wont heat up..

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Luca Sclisizzo @luca-sclisizzo.bsky.social · 28/11/2025

A desk I won't forget! This week I completed my internship at WashU: such an amazing period! Thanks to @ecjohnson.bsky.social to open her lab to me and all the people I worked, discussed and learned with (pumpkin included🎃).

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Reposted by Luca Sclisizzo

Ted Schwaba @tedmond.bsky.social · 17/11/2025

The paper you linked is one of my all time faves. It really forced me to consider the fundamental constraints on the research I do for a living. Yes! And also, what *is* stochasticity? is it true randomness, or some emergent chaos-emerging-from-minute-differences-in-environment thing?

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Luca Sclisizzo @luca-sclisizzo.bsky.social · 16/11/2025

Cool! I do remember attending a session in ECP21 were this paper (doi.org/10.1038/ncom...) was discussed, cool stuff! Would you think that stocasticity might be the key factor here? And could it actually be a source of variability behind individual differences in humans?

doi.org

Behavioural individuality in clonal fish arises despite near-identical rearing conditions - Nature Communications

Genetically-identical animals experiencing the same environmental conditions should develop, in theory, identical behavioral traits. However, Bierbachet al. show here that behavioral differences still...

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Reposted by Luca Sclisizzo

Psychiatric Genomics Consortium (PGC) @pgcgenetics.bsky.social · 24/09/2025

A new preprint reports the largest genetic study of schizophrenia in people of African ancestry, identifying 3 genetic signals unique to this group using data from the Million Veteran Program (MVP) and the All of Us Research Program: pubmed.ncbi.nlm.nih.gov/39252912/

pubmed.ncbi.nlm.nih.gov

Biological Insights from Schizophrenia-associated Loci in Ancestral Populations - PubMed

Large-scale genome-wide association studies of schizophrenia have uncovered hundreds of associated loci but with extremely limited representation of African diaspora populations. We surveyed electroni...

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Reposted by Luca Sclisizzo

Emanuele Esposito @emanueleesposito.bsky.social · 23/08/2025

Are you a clinician and you want to understand how an evolutionary framework can be applied in psychotherapy? 🧬🧠 Here's a good news for you! A new workshop will be held in the beautiful city of Erice, Sicily, in April 2026! centromajorana.it/evopsychothe...

centromajorana.it

Evolution in psychotherapy: Current approaches and new directions

'Ettore Majorana' Foundation and International Centre for Scientific Culture Schools

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